Tobias Claff

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 15

Top Topics

Molecular Dynamics Simulations

Neuropathic Pain

Respiratory Syndrome Coronavirus

Structure Activity Relationship

Top Venues

Science (New York, N.Y.)

Journal of medicinal chemistry

ACS pharmacology & translational science

Communications chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Julian Breidenbach, Rabea Voget, Yaoyao Si, Alexandra Hingst, Tobias Claff, Katharina Sylvester, Valentina Wolf, Vesa Krasniqi, Abibe Useini, Norbert Sträter, Yukino Ogura, Atsushi Kawaguchi, Christa Elisabeth Müller, Michael Gütschow
Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV-2 Main Protease Inhibitors as Antiviral Drugs. Journal of medicinal chemistry 67 (11) (2024)
Julian Breidenbach, Rabea Voget, Yaoyao Si, Alexandra Hingst, Tobias Claff, Katharina Sylvester, Valentina Wolf, Vesa Krasniqi, Abibe Useini, Norbert Sträter, Yukino Ogura, Atsushi Kawaguchi, Christa Elisabeth Müller, Michael Gütschow
Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV-2 Main Protease Inhibitors as Antiviral Drugs. Journal of medicinal chemistry (2024)
Angelo Oneto, Ghazl Al Hamwi, Laura Schäkel, Nadine Krüger, Katharina Sylvester, Marvin Petry, Rasha Abu Shamleh, Thanigaimalai Pillaiyar, Tobias Claff, Anke C Schiedel, Norbert Sträter, Michael Gütschow, Christa Elisabeth Müller
Nonpeptidic Irreversible Inhibitors of SARS-CoV-2 Main Protease with Potent Antiviral Activity. Journal of medicinal chemistry (2024)
Tobias Claff, Andhika B Mahardhika, Victoria J Vaaßen, Jonathan G Schlegel, Christin Vielmuth, Renato H Weiße, Norbert Sträter, Christa E Müller
Structural Insights into Partial Activation of the Prototypic G Protein-Coupled Adenosine A 2A Receptor. ACS pharmacology & translational science 7 (5) (2024)
Julian Breidenbach, Rabea Voget, Yaoyao Si, Alexandra Hingst, Tobias Claff, Katharina Sylvester, Valentina Wolf, Vesa Krasniqi, Abibe Useini, Norbert Sträter, Yukino Ogura, Atsushi Kawaguchi, Christa Elisabeth Müller, Michael Gütschow
Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV-2 Main Protease Inhibitors as Antiviral Drugs. Journal of medicinal chemistry (2024)
Tobias Claff, Andhika B Mahardhika, Victoria J Vaaßen, Jonathan G Schlegel, Christin Vielmuth, Renato H Weiße, Norbert Sträter, Christa E Müller
Structural Insights into Partial Activation of the Prototypic G Protein-Coupled Adenosine A 2A Receptor. ACS pharmacology & translational science 7 (5) (2024)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Tobias Claff, Jonathan G Schlegel, Jan Hendrik Voß, Victoria J Vaaßen, Renato H Weiße, Robert K Y Cheng, Sandra Markovic-Mueller, Denis Bucher, Norbert Sträter, Christa Elisabeth Müller
Crystal structure of adenosine A 2A receptor in complex with clinical candidate Etrumadenant reveals unprecedented antagonist interaction. Communications chemistry 6 (1) (2023)
Christa E Müller, Tobias Claff
Activated microglia nibbling glycosaminoglycans from spinal cord perineural nets: a new mechanism for neuropathic pain. Signal transduction and targeted therapy 7 (1) (2022)
Ahmed Temirak, Jonathan G Schlegel, Jan Hendrik Voß, Victoria J Vaaßen, Christin Vielmuth, Tobias Claff, Christa Elisabeth Müller
Irreversible Antagonists for the Adenosine A 2B Receptor. Molecules (Basel, Switzerland) 27 (12) (2022)
Tobias Claff, Tim A Klapschinski, Udaya K Tiruttani Subhramanyam, Victoria J Vaaßen, Jonathan G Schlegel, Christin Vielmuth, Jan Hendrik Voß, Jörg Labahn, Christa Elisabeth Müller
Single Stabilizing Point Mutation Enables High-Resolution Co-Crystal Structures of the Adenosine A 2A Receptor with Preladenant Conjugates. Angewandte Chemie (International ed. in English) 61 (22) (2022)
Tobias Claff, Jing Yu, Véronique Blais, Nilkanth Patel, Charlotte Martin, Li-Jie Wu, Gye Won Han, Brian J Holleran, Olivier Van der Poorten, Kate L White, Michael A Hanson, Philippe Sarret, Louis Gendron, Vadim Cherezov, Vsevolod Katritch, Steven Ballet, Zhi-Jie Liu, Christa Elisabeth Müller, Raymond C Stevens
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists. Science advances 5 (11) (2019)