Ultan McDermott

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 22

Top Venues

Cancer discovery

Nature communications

Communications biology

Scientific reports

AstraZeneca UK Ltd

This page only lists publications with an associated author ORCID identifier.

Affiliation History

AstraZeneca UK Ltd Dec 01 2017

United Kingdom

Chief Scientist :: Oncology

Cambridge University Hospitals Nov 01 2009

United Kingdom

Honorary Consultant Oncologist :: Oncology

Wellcome Sanger Institute Jun 15 2009

United Kingdom

Honorary Faculty

Publications

Azadeh C Bashi, Elizabeth A Coker, Krishna C Bulusu, Patricia Jaaks, Claire Crafter, Howard Lightfoot, Marta Milo, Katrina McCarten, David F Jenkins, Dieudonne van der Meer, James T Lynch, Syd Barthorpe, Courtney L Andersen, Simon T Barry, Alexandra Beck, Justin Cidado, Jacob A Gordon, Caitlin Hall, James A Hall, Iman Mali, Tatiana Mironenko, Kevin Mongeon, James Morris, Laura Richardson, Paul D Smith, Omid Tavana, Charlotte Tolley, Frances Thomas, Brandon S Willis, Wanjuan Yang, Lenka Oplustil O'Connor, Ultan McDermott, Susan E Critchlow, Lisa Drew, Stephen E Fawell, Jerome T Mettetal, Mathew J Garnett
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations. Cancer discovery 14 (5) (2024)
Matthias Pfeifer, Jonathan S Brammeld, Stacey Price, James Pilling, Deepa Bhavsar, Anca Farcas, Jessica Bateson, Anjana Sundarrajan, Ricardo J Miragaia, Nin Guan, Stephanie Arnold, Laiba Tariq, Michael Grondine, Sarah Talbot, Maria Lisa Guerriero, Daniel J O'Neill, Jamie Young, Carlos Company, Shanade Dunn, Hannah Thorpe, Matthew J Martin, Kimberly Maratea, Daniel Barrell, Miika Ahdesmaki, Jerome T Mettetal, null null, James Brownell, Ultan McDermott
Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer. Communications biology 7 (1) (2024)
Matthias Pfeifer, Jonathan S Brammeld, Stacey Price, James Pilling, Deepa Bhavsar, Anca Farcas, Jessica Bateson, Anjana Sundarrajan, Ricardo J Miragaia, Nin Guan, Stephanie Arnold, Laiba Tariq, Michael Grondine, Sarah Talbot, Maria Lisa Guerriero, Daniel J O'Neill, Jamie Young, Carlos Company, Shanade Dunn, Hannah Thorpe, Matthew J Martin, Kimberly Maratea, Daniel Barrell, Miika Ahdesmaki, Jerome T Mettetal, null null, James Brownell, Ultan McDermott
Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer. Communications biology 7 (1) (2024)
Matthias Pfeifer, Jonathan S Brammeld, Stacey Price, James Pilling, Deepa Bhavsar, Anca Farcas, Jessica Bateson, Anjana Sundarrajan, Ricardo J Miragaia, Nin Guan, Stephanie Arnold, Laiba Tariq, Michael Grondine, Sarah Talbot, Maria Lisa Guerriero, Daniel J O'Neill, Jamie Young, Carlos Company, Shanade Dunn, Hannah Thorpe, Matthew J Martin, Kimberly Maratea, Daniel Barrell, Miika Ahdesmaki, Jerome T Mettetal, null null, James Brownell, Ultan McDermott
Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer. Communications biology 7 (1) (2024)
Matthias Pfeifer, Jonathan S Brammeld, Stacey Price, James Pilling, Deepa Bhavsar, Anca Farcas, Jessica Bateson, Anjana Sundarrajan, Ricardo J Miragaia, Nin Guan, Stephanie Arnold, Laiba Tariq, Michael Grondine, Sarah Talbot, Maria Lisa Guerriero, Daniel J O'Neill, Jamie Young, Carlos Company, Shanade Dunn, Hannah Thorpe, Matthew J Martin, Kimberly Maratea, Daniel Barrell, Miika Ahdesmaki, Jerome T Mettetal, null null, James Brownell, Ultan McDermott
Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer. Communications biology 7 (1) (2024)
Azadeh C Bashi, Elizabeth A Coker, Krishna C Bulusu, Patricia Jaaks, Claire Crafter, Howard Lightfoot, Marta Milo, Katrina McCarten, David F Jenkins, Dieudonne van der Meer, James T Lynch, Syd Barthorpe, Courtney L Andersen, Simon T Barry, Alexandra Beck, Justin Cidado, Jacob A Gordon, Caitlin Hall, James A Hall, Iman Mali, Tatiana Mironenko, Kevin Mongeon, James Morris, Laura Richardson, Paul D Smith, Omid Tavana, Charlotte Tolley, Frances Thomas, Brandon S Willis, Wanjuan Yang, Lenka Oplustil O'Connor, Ultan McDermott, Susan E Critchlow, Lisa Drew, Stephen E Fawell, Jerome T Mettetal, Mathew J Garnett
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations. Cancer discovery (2024)
Azadeh C Bashi, Elizabeth A Coker, Krishna C Bulusu, Patricia Jaaks, Claire Crafter, Howard Lightfoot, Marta Milo, Katrina McCarten, David F Jenkins, Dieudonne van der Meer, James T Lynch, Syd Barthorpe, Courtney L Andersen, Simon T Barry, Alexandra Beck, Justin Cidado, Jacob A Gordon, Caitlin Hall, James A Hall, Iman Mali, Tatiana Mironenko, Kevin Mongeon, James Morris, Laura Richardson, Paul D Smith, Omid Tavana, Charlotte Tolley, Frances Thomas, Brandon S Willis, Wanjuan Yang, Lenka Oplustil O'Connor, Ultan McDermott, Susan E Critchlow, Lisa Drew, Stephen E Fawell, Jerome T Mettetal, Mathew J Garnett
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations. Cancer discovery 14 (5) (2024)
Azadeh C Bashi, Elizabeth A Coker, Krishna C Bulusu, Patricia Jaaks, Claire Crafter, Howard Lightfoot, Marta Milo, Katrina McCarten, David F Jenkins, Dieudonne van der Meer, James T Lynch, Syd Barthorpe, Courtney L Andersen, Simon T Barry, Alexandra Beck, Justin Cidado, Jacob A Gordon, Caitlin Hall, James A Hall, Iman Mali, Tatiana Mironenko, Kevin Mongeon, James Morris, Laura Richardson, Paul D Smith, Omid Tavana, Charlotte Tolley, Frances Thomas, Brandon S Willis, Wanjuan Yang, Lenka Oplustil O'Connor, Ultan McDermott, Susan E Critchlow, Lisa Drew, Stephen E Fawell, Jerome T Mettetal, Mathew J Garnett
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations. Cancer discovery 14 (5) (2024)
Azadeh C Bashi, Elizabeth A Coker, Krishna C Bulusu, Patricia Jaaks, Claire Crafter, Howard Lightfoot, Marta Milo, Katrina McCarten, David F Jenkins, Dieudonne van der Meer, James T Lynch, Syd Barthorpe, Courtney L Andersen, Simon T Barry, Alexandra Beck, Justin Cidado, Jacob A Gordon, Caitlin Hall, James A Hall, Iman Mali, Tatiana Mironenko, Kevin Mongeon, James Morris, Laura Richardson, Paul D Smith, Omid Tavana, Charlotte Tolley, Frances Thomas, Brandon S Willis, Wanjuan Yang, Lenka Oplustil O'Connor, Ultan McDermott, Susan E Critchlow, Lisa Drew, Stephen E Fawell, Jerome T Mettetal, Mathew J Garnett
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations. Cancer discovery 14 (5) (2024)
Azadeh C Bashi, Elizabeth A Coker, Krishna C Bulusu, Patricia Jaaks, Claire Crafter, Howard Lightfoot, Marta Milo, Katrina McCarten, David F Jenkins, Dieudonne van der Meer, James T Lynch, Syd Barthorpe, Courtney L Andersen, Simon T Barry, Alexandra Beck, Justin Cidado, Jacob A Gordon, Caitlin Hall, James A Hall, Iman Mali, Tatiana Mironenko, Kevin Mongeon, James Morris, Laura Richardson, Paul D Smith, Omid Tavana, Charlotte Tolley, Frances Thomas, Brandon S Willis, Wanjuan Yang, Lenka Oplustil O'Connor, Ultan McDermott, Susan E Critchlow, Lisa Drew, Stephen E Fawell, Jerome T Mettetal, Mathew J Garnett
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations. Cancer discovery (2024)
Anna Gogleva, Dimitris Polychronopoulos, Matthias Pfeifer, Vladimir Poroshin, Michaël Ughetto, Matthew J Martin, Hannah Thorpe, Aurelie Bornot, Paul D Smith, Ben Sidders, Jonathan R Dry, Miika Ahdesmäki, Ultan McDermott, Eliseo Papa, Krishna C Bulusu
Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer. Nature communications 13 (1) (2022)
Jonathan C M Wan, Katrin Heider, Davina Gale, Suzanne Murphy, Eyal Fisher, Florent Mouliere, Andrea Ruiz-Valdepenas, Angela Santonja, James Morris, Dineika Chandrananda, Andrea Marshall, Andrew B Gill, Pui Ying Chan, Emily Barker, Gemma Young, Wendy N Cooper, Irena Hudecova, Francesco Marass, Richard Mair, Kevin M Brindle, Grant D Stewart, Jean E Abraham, Carlos Caldas, Doris M Rassl, Robert C Rintoul, Constantine Alifrangis, Mark Ross Middleton, Ferdia A Gallagher, Christine Parkinson, Amer Durrani, Ultan McDermott, Christopher G Smith, Charles E Massie, Philippa Corrie, Nitzan Rosenfeld
ctDNA monitoring using patient-specific sequencing and integration of variant reads. Science translational medicine 12 (548) (2021)
Monique B Nilsson, Huiying Sun, Jacqulyne P Robichaux, Matthias Pfeifer, Ultan McDermott, Jon Travers, Lixia Diao, Yuanxin Xi, Pan Tong, Li Shen, Mia Hofstad, Masanori Kawakami, Xiuning Le, Xi Liu, Youhong Fan, Alissa Poteete, Limei Hu, Marcelo Vailati Negrão, Hai T Tran, Ethan Dmitrovsky, David H Peng, Don L Gibbons, Jing Wang, John Victor Heymach
A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components. Science translational medicine 12 (559) (2021)
Hayley E Francies, Ultan McDermott, Mathew J Garnett
Genomics-guided pre-clinical development of cancer therapies. Nature cancer 1 (5) (2020)
Francesco Iorio, Luz Garcia-Alonso, Jonathan S Brammeld, Iňigo Martincorena, David R Wille, Ultan McDermott, Julio Saez-Rodriguez
Pathway-based dissection of the genomic heterogeneity of cancer hallmarks' acquisition with SLAPenrich. Scientific reports 8 (1) (2018)
Grace Collord, Patrick Tarpey, Natalja Kurbatova, Inigo Martincorena, Sebastian Moran, Manuel Castro, Tibor Nagy, Graham Bignell, Francesco Maura, Matthew D Young, Jorge Berna, Jose M C Tubio, Christopher E McMurran, Adam M H Young, Mathijs Sanders, Imran Noorani, Stephen J Price, Colin Watts, Elke Leipnitz, Matthias Kirsch, Gabriele Schackert, Danita Pearson, Abel Devadass, Zvi Ram, V Peter Collins, Kieren Allinson, Michael D Jenkinson, Rasheed Zakaria, Khaja Syed, C Oliver Hanemann, Jemma Dunn, Michael W McDermott, Ramez W Kirollos, George S Vassiliou, Manel Esteller, Sam Behjati, Alvis Brazma, Thomas Santarius, Ultan McDermott
An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures. Scientific reports 8 (1) (2018)
Michael P Menden, Francesco Paolo Casale, Johannes Stephan, Graham R Bignell, Francesco Iorio, Ultan McDermott, Mathew J Garnett, Julio Saez-Rodriguez, Oliver Stegle
The germline genetic component of drug sensitivity in cancer cell lines. Nature communications 9 (1) (2018)
Steven P Williams, Andrew S Barthorpe, Howard Lightfoot, Mathew J Garnett, Ultan McDermott
High-throughput RNAi screen for essential genes and drug synergistic combinations in colorectal cancer. Scientific data 4 (2017)
Niedzica Camacho, Peter Van Loo, Sandra Edwards, Jonathan D Kay, Lucy Matthews, Kerstin Haase, Jeremy Clark, Nening Dennis, Sarah Thomas, Barbara Kremeyer, Jorge Zamora, Adam P Butler, Gunes Gundem, Sue Merson, Hayley Luxton, Steve Hawkins, Mohammed Ghori, Luke Marsden, Adam Lambert, Katalin Karaszi, Gill Pelvender, Charlie E Massie, ZSofia Kote-Jarai, Keiran M Raine, David Jones, William J Howat, Steven Hazell, Naomi Livni, Cyril Fisher, Christopher Ogden, Pardeep Kumar, Alan Thompson, David Nicol, Erik K Mayer, Timothy J Dudderidge, Yongwei Yu, Hongwei Zhang, Nimish C Shah, Vincent J Gnanapragasam, null null, William Isaacs, Tapio Visakorpi, Freddie C Hamdy, Daniel M Berney, Clare Verrill, Anne Y Warren, David C Wedge, Andrew G Lynch, Christopher S Foster, Yong Jie Lu, G Steven Bova, Hayley C Whitaker, Ultan McDermott, David E Neal, Rosalind A Eeles, Colin S Cooper, Daniel S Brewer
Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data. PLoS genetics 13 (9) (2017)
Sam Behjati, Patrick S Tarpey, Kerstin Haase, Hongtao Ye, Matthew D Young, Ludmil B Alexandrov, Sarah J Farndon, Grace Collord, David C Wedge, Inigo Martincorena, Susanna L Cooke, Helen Davies, William Mifsud, Mathias Lidgren, Sancha Martin, Calli Latimer, Mark Maddison, Adam P Butler, Jon W Teague, Nischalan Pillay, Adam Shlien, Ultan McDermott, P Andrew Futreal, Daniel Baumhoer, Olga Zaikova, Bodil Bjerkehagen, Ola Myklebost, M Fernanda Amary, Roberto Tirabosco, Peter Van Loo, Michael R Stratton, Adrienne M Flanagan, Peter J Campbell
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma. Nature communications 8 (2017)
Moritz Gerstung, Elli Papaemmanuil, Inigo Martincorena, Lars Bullinger, Verena I Gaidzik, Peter Paschka, Michael Heuser, Felicitas Thol, Niccolo Bolli, Peter Ganly, Arnold Ganser, Ultan McDermott, Konstanze Döhner, Richard F Schlenk, Hartmut Döhner, Peter J Campbell
Precision oncology for acute myeloid leukemia using a knowledge bank approach. Nature genetics 49 (3) (2017)
Sam Behjati, Gunes Gundem, David C Wedge, Nicola D Roberts, Patrick S Tarpey, Susanna L Cooke, Peter Van Loo, Ludmil B Alexandrov, Manasa Ramakrishna, Helen Davies, Serena Nik-Zainal, Claire Hardy, Calli Latimer, Keiran M Raine, Lucy Stebbings, Andy Menzies, David Jones, Rebecca Shepherd, Adam P Butler, Jon W Teague, Mette Jorgensen, Bhavisha Khatri, Nischalan Pillay, Adam Shlien, P Andrew Futreal, Christophe Badie, null null, Ultan McDermott, G Steven Bova, Andrea L Richardson, Adrienne M Flanagan, Michael R Stratton, Peter J Campbell
Mutational signatures of ionizing radiation in second malignancies. Nature communications 7 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ultan McDermott