Francesco Iorio (F Iorio)

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 26

Top Topics

Multiple Myeloma

Dna Methylation

Top Venues

Nature communications

Molecular systems biology

The CRISPR journal

This page only lists publications with an associated author ORCID identifier.

Publications

Raffaele M Iannuzzi, Ichcha Manipur, Clare Pacini, Fiona M Behan, Mario R Guarracino, Mathew J Garnett, Aurora Savino, Francesco Iorio
Benchmark Software and Data for Evaluating CRISPR-Cas9 Experimental Pipelines Through the Assessment of a Calibration Screen. The CRISPR journal (2024)
Alessandro Vinceti, Raffaele M Iannuzzi, Isabella Boyle, Lucia Trastulla, Catarina D Campbell, Francisca Vazquez, Joshua M Dempster, Francesco Iorio
A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data. Genome biology 25 (1) (2024)
Lucia Trastulla, Georgii Dolgalev, Sylvain Moser, Laura T Jiménez-Barrón, Till F M Andlauer, Moritz von Scheidt, null null, Monika Budde, Urs Heilbronner, Sergi Papiol, Alexander Teumer, Georg Homuth, Henry Völzke, Marcus Dörr, Peter Falkai, Thomas G Schulze, Julien Gagneur, Francesco Iorio, Bertram Müller-Myhsok, Heribert Schunkert, Michael J Ziller
Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature communications 15 (1) (2024)
Alessandro Vinceti, Raffaele M Iannuzzi, Isabella Boyle, Lucia Trastulla, Catarina D Campbell, Francisca Vazquez, Joshua M Dempster, Francesco Iorio
A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data. Genome biology 25 (1) (2024)
Lucia Trastulla, Georgii Dolgalev, Sylvain Moser, Laura T Jiménez-Barrón, Till F M Andlauer, Moritz von Scheidt, null null, Monika Budde, Urs Heilbronner, Sergi Papiol, Alexander Teumer, Georg Homuth, Henry Völzke, Marcus Dörr, Peter Falkai, Thomas G Schulze, Julien Gagneur, Francesco Iorio, Bertram Müller-Myhsok, Heribert Schunkert, Michael J Ziller
Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature communications 15 (1) (2024)
Alessandro Vinceti, Raffaele M Iannuzzi, Isabella Boyle, Lucia Trastulla, Catarina D Campbell, Francisca Vazquez, Joshua M Dempster, Francesco Iorio
A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data. Genome biology 25 (1) (2024)
Raffaele M Iannuzzi, Ichcha Manipur, Clare Pacini, Fiona M Behan, Mario R Guarracino, Mathew J Garnett, Aurora Savino, Francesco Iorio
Benchmark Software and Data for Evaluating CRISPR-Cas9 Experimental Pipelines Through the Assessment of a Calibration Screen. The CRISPR journal (2024)
Lucia Trastulla, Georgii Dolgalev, Sylvain Moser, Laura T Jiménez-Barrón, Till F M Andlauer, Moritz von Scheidt, null null, Monika Budde, Urs Heilbronner, Sergi Papiol, Alexander Teumer, Georg Homuth, Henry Völzke, Marcus Dörr, Peter Falkai, Thomas G Schulze, Julien Gagneur, Francesco Iorio, Bertram Müller-Myhsok, Heribert Schunkert, Michael J Ziller
Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature communications 15 (1) (2024)
Lucia Trastulla, Georgii Dolgalev, Sylvain Moser, Laura T Jiménez-Barrón, Till F M Andlauer, Moritz von Scheidt, null null, Monika Budde, Urs Heilbronner, Sergi Papiol, Alexander Teumer, Georg Homuth, Henry Völzke, Marcus Dörr, Peter Falkai, Thomas G Schulze, Julien Gagneur, Francesco Iorio, Bertram Müller-Myhsok, Heribert Schunkert, Michael J Ziller
Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature communications 15 (1) (2024)
Katia Grillone, Serena Ascrizzi, Paolo Cremaschi, Jussara Amato, Nicoletta Polerà, Ottavio Croci, Roberta Rocca, Caterina Riillo, Francesco Conforti, Raffaele Graziano, Diego Brancaccio, Daniele Caracciolo, Stefano Alcaro, Bruno Pagano, Antonio Randazzo, Pierosandro Tagliaferri, Francesco Iorio, Pierfrancesco Tassone
An unbiased lncRNAs dropout CRISPR-Cas9 screen reveals RP11-350G8.5 as a novel therapeutic target for Multiple Myeloma. Blood (2024)
Alessandro Vinceti, Lucia Trastulla, Umberto Perron, Andrea Raiconi, Francesco Iorio
A heuristic algorithm solving the mutual-exclusivity-sorting problem. Bioinformatics (Oxford, England) 39 (1) (2023)
Lucia Trastulla, Aurora Savino, Pedro Beltrao, Isidro Cortés Ciriano, Peter Fenici, Mathew J Garnett, Ilaria Guerini, Nuria Lòpez Bigas, Iain Mattaj, Evangelia Petsalaki, Laura Riva, Christopher J Tape, Sumana Sharma, Francisca Vazquez, Francesco Iorio
Highlights from the 1st European cancer dependency map symposium and workshop. FEBS letters (2023)
Lucia Trastulla, Javad Noorbakhsh, Francisca Vazquez, James M McFarland, Francesco Iorio
Computational estimation of quality and clinical relevance of cancer cell lines. Molecular systems biology 18 (7) (2022)
Jacob Househam, Timon Heide, George D Cresswell, Inmaculada Spiteri, Chris Kimberley, Luis Zapata, Claire Lynn, Chela James, Maximilian Mossner, Javier Fernandez-Mateos, Alessandro Vinceti, Ann-Marie C Baker, Calum Gabbutt, Alison Berner, Melissa Schmidt, Bingjie Chen, Eszter Lakatos, Vinaya Gunasri, Daniel Nichol, Helena Costa, Miriam Mitchinson, Daniele Ramazzotti, Benjamin Werner, Francesco Iorio, Marnix Jansen, Giulio Caravagna, Christopher P Barnes, Darryl Shibata, John A Bridgewater, Manuel Rodriguez, Luca Magnani, Andrea Sottoriva, Trevor A Graham
Phenotypic plasticity and genetic control in colorectal cancer evolution. Nature 611 (7937) (2022)
Nicola A Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona M Behan, Emanuel Gonçalves, Anneliese O Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J Garnett, Stephen P Jackson, David J Adams
Combinatorial CRISPR screen identifies fitness effects of gene paralogues. Nature communications 12 (1) (2021)
Clare Pacini, Joshua M Dempster, Isabella Boyle, Emanuel Gonçalves, Hanna Najgebauer, Emre Karakoc, Dieudonne van der Meer, Andrew Barthorpe, Howard Lightfoot, Patricia Jaaks, James M McFarland, Mathew J Garnett, Aviad Tsherniak, Francesco Iorio
Integrated cross-study datasets of genetic dependencies in cancer. Nature communications 12 (1) (2021)
Bachisio Ziccheddu, Matteo Claudio Da Via, Marta Lionetti, Akihiro Maeda, Silvia Morlupi, Matteo Dugo, Katia Todoerti, Stefania Oliva, Mattia D'Agostino, Paolo Corradini, Carl Ola Landgren, Francesco Iorio, Loredana Pettine, Alessandra Pompa, Martina Manzoni, Luca Baldini, Antonino Neri, Francesco Maura, Niccolo' Bolli
Functional Impact of Genomic Complexity on the Transcriptome of Multiple Myeloma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (23) (2021)
Alessandro Vinceti, Emre Karakoc, Clare Pacini, Umberto Perron, Riccardo Roberto De Lucia, Mathew J Garnett, Francesco Iorio
CoRe: a robustly benchmarked R package for identifying core-fitness genes in genome-wide pooled CRISPR-Cas9 screens. BMC genomics 22 (1) (2021)
Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, Gabriele Picco, Fiona M Behan, Patricia Jaaks, Elizabeth A Coker, Donny van der Meer, Andrew Barthorpe, Howard Lightfoot, Tatiana Mironenko, Alexandra Beck, Laura Richardson, Wanjuan Yang, Ermira Lleshi, James Hall, Charlotte Tolley, Caitlin Hall, Iman Mali, Frances Thomas, James Morris, Andrew R Leach, James T Lynch, Ben Sidders, Claire Crafter, Francesco Iorio, Stephen Fawell, Mathew J Garnett
Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens. Molecular systems biology 16 (7) (2021)
Eirini Christodoulou, Mamunur Rashid, Clare Pacini, Alastair Droop, Holly Robertson, Tim van Groningen, Amina F A S Teunisse, Francesco Iorio, Aart G Jochemsen, David J Adams, Remco van Doorn
Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma. Pigment cell & melanoma research 34 (1) (2020)
Gabriele Picco, Elisabeth D Chen, Luz Garcia Alonso, Fiona M Behan, Emanuel Gonçalves, Graham Bignell, Angela Matchan, Beiyuan Fu, Ruby Banerjee, Elizabeth Anderson, Adam Butler, Cyril H Benes, Ultan McDermott, David Dow, Francesco Iorio, Euan Stronach, Fengtang Yang, Kosuke Yusa, Julio Saez-Rodriguez, Mathew J Garnett
Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening. Nature communications 10 (1) (2019)
Joshua M Dempster, Clare Pacini, Sasha Pantel, Fiona M Behan, Thomas Green, John Michael Krill-Burger, Charlotte M Beaver, Scott T Younger, Victor Zhivich, Hanna Najgebauer, Felicity Allen, Emanuel Gonçalves, Rebecca Shepherd, John G Doench, Kosuke Yusa, Francisca Vazquez, Leopold Parts, Jesse S Boehm, Todd R Golub, William C Hahn, David E Root, Mathew J Garnett, Aviad Tsherniak, Francesco Iorio
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets. Nature communications 10 (1) (2019)
Francesco Iorio, Luz Garcia-Alonso, Jonathan S Brammeld, Iňigo Martincorena, David R Wille, Ultan McDermott, Julio Saez-Rodriguez
Pathway-based dissection of the genomic heterogeneity of cancer hallmarks' acquisition with SLAPenrich. Scientific reports 8 (1) (2018)
Michael P Menden, Francesco Paolo Casale, Johannes Stephan, Graham R Bignell, Francesco Iorio, Ultan McDermott, Mathew J Garnett, Julio Saez-Rodriguez, Oliver Stegle
The germline genetic component of drug sensitivity in cancer cell lines. Nature communications 9 (1) (2018)
Francesco Iorio, Marti Bernardo-Faura, Andrea Gobbi, Thomas Cokelaer, Giuseppe Jurman, Julio Saez-Rodriguez
Efficient randomization of biological networks while preserving functional characterization of individual nodes. BMC bioinformatics 17 (1) (2016)
Annalisa Mupo, M Seiler, V Sathiaseelan, A Pance, Y Yang, A A Agrawal, Francesco Iorio, R Bautista, S Pacharne, K Tzelepis, N Manes, P Wright, E Papaemmanuil, D G Kent, P C Campbell, S Buonamici, Niccolo' Bolli, G S Vassiliou
Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts. Leukemia 31 (3) (2016)