Wei Zheng

ResearcherID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 35

Top Venues

Orphanet journal of rare diseases

British journal of pharmacology

PloS one

Cell discovery

National Institutes of Health

University at Buffalo - The State University of New York (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Institutes of Health

United States

Group Leader :: Therapeutics for Rare and Neglected Diseases

Merck and Co Inc West Point

United States

Sr. Research Fellow :: Automatic Biotechnology

Berlex Biosciences

United States

Scientist :: Biology

University at Buffalo - The State University of New York

United States

Postdoctoral fellow :: Biochemical Pharmacology

Education History

University at Buffalo - The State University of New York

United States

PHD :: Biochemical Pharmacology

Zhejiang University School of Medicine

China

MSC :: Pharmacology

Publications

Peng Gao, Qi Zhang, Devin Keely, Don W Cleveland, Yihong Ye, Wei Zheng, Min Shen, Haiyang Yu
Molecular Graph-Based Deep Learning Algorithm Facilitates an Imaging-Based Strategy for Rapid Discovery of Small Molecules Modulating Biomolecular Condensates. Journal of medicinal chemistry (2023)
Qi Zhang, Weichun Tang, Eduardo Stancanelli, Eunkyung Jung, Zulfeqhar A Syed, Vijayakanth Pagadala, Layla Saidi, Catherine Z Chen, Peng Gao, Miao Xu, Ivan Pavlinov, Bing Li, Wenwei Huang, Liqiang Chen, Jian Liu, Hang Xie, Wei Zheng, Yihong Ye
Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation. Nature communications 14 (1) (2023)
Ivan Pavlinov, Mitali Tambe, Joshua M Abbott, Ha Nam Nguyen, Miao Xu, Manisha Pradhan, Atena Farkhondeh, Wei Zheng
In depth characterization of midbrain organoids derived from wild type iPSC lines. PloS one 18 (10) (2023)
Qi Zhang, Wei-Chun Tang, Eduardo Stancanelli, Eunkyung Jung, Zulfeqhar A Syed, Vijayakanth Pagadala, Layla Saidi, Catherine Z Chen, Peng Gao, Miao Xu, Ivan Pavlinov, Bing Li, Wenwei Huang, Liqiang Chen, Jian Liu, Hang Xie, Wei Zheng, Yihong Ye
Heparan sulfate promotes ACE2 super-cluster assembly to enhance SARS-CoV-2-associated syncytium formation. Research square (2023)
Holly Y Chen, Manju Swaroop, Samantha Papal, Anupam Mondal, Hyun Beom Song, Laura Campello, Gregory Tawa, Florian Regent, Hiroko Shimada, Kunio Nagashima, Natalia de Val, Samuel G Jacobson, Wei Zheng, Anand Swaroop
Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects. eLife 12 (2023)
Phillip R Sanchez, Sarah A Head, Shan Qian, Haibo Qiu, Avishek Roy, Zhendong Jin, Wei Zheng, Jun O Liu
Modulation of the Endomembrane System by the Anticancer Natural Product Superstolide/ZJ-101. International journal of molecular sciences 24 (11) (2023)
Seung Bum Park, Parker Irvin, Zongyi Hu, Mohsin Khan, Xin Hu, Qiru Zeng, Catherine Chen, Miao Xu, Madeleine Leek, Ruochen Zang, James Brett Case, Wei Zheng, Siyuan Ding, Tsanyang Jake Liang
Targeting the Fusion Process of SARS-CoV-2 Infection by Small Molecule Inhibitors. mBio (2022)
Ying Fu, Juliana da Fonseca Rezende E Mello, Bryan D Fleming, Alex Renn, Catherine Z Chen, Xin Hu, Miao Xu, Kirill Gorshkov, Quinlin Hanson, Wei Zheng, Emily M Lee, Lalith Perera, Robert Petrovich, Manisha Pradhan, Richard T Eastman, Zina Itkin, Thomas B Stanley, Allen L Hsu, Venkata Dandey, Kedar Sharma, William Gillette, Troy Taylor, Nitya Ramakrishnan, Shelley Perkins, Dominic Esposito, Eunkeu Oh, Kimihiro Susumu, Mason Wolak, Marc Ferrer, Matthew D Hall, Mario J Borgnia, Anton Simeonov
A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike. PloS one 17 (8) (2022)
Oscar Solis, Andrea Rosario Beccari, Daniela Iaconis, Carmine Talarico, Camilo A Ruiz-Bedoya, Jerome C Nwachukwu, Annamaria Cimini, Vanessa Castelli, Riccardo Bertini, Monica Montopoli, Veronica Cocetta, Stefano Borocci, Ingrid Guarnetti Prandi, Kelly Flavahan, Melissa Bahr, Anna Napiorkowski, Giovanni Chillemi, Masato Ooka, Xiaoping Yang, Shiliang Zhang, Menghang Xia, Wei Zheng, Jordi Bonaventura, Martin G Pomper, Jody E Hooper, Marisela Morales, Avi Z Rosenberg, Kendall W Nettles, Sanjay K Jain, Marcello Allegretti, Michael Michaelides
The SARS-CoV-2 spike protein binds and modulates estrogen receptors. Science advances 8 (48) (2022)
Durbadal Ojha, Clayton W Winkler, Jacqueline M Leung, Tyson A Woods, Catherine Z Chen, Vinod Nair, Katherine Taylor, Charles D Yeh, Gregory J Tawa, Charles L Larson, Wei Zheng, Cathryn L Haigh, Karin E Peterson
Rottlerin inhibits La Crosse virus-induced encephalitis in mice and blocks release of replicating virus from the Golgi body in neurons. Nature microbiology 6 (11) (2021)
Yu-Shan Cheng, Jose Santinni Roma, Min Shen, Caroline Mota Fernandes, Patricia S Tsang, He Eun Forbes, Helena Boshoff, Cristina Lazzarini, Maurizio Del Poeta, Wei Zheng, Peter R Williamson
Identification of Antifungal Compounds against Multidrug-Resistant Candida auris Utilizing a High-Throughput Drug-Repurposing Screen. Antimicrobial agents and chemotherapy 65 (4) (2021)
Ruili Huang, Miao Xu, Hu Zhu, Catherine Z Chen, Wei Zhu, Emily M Lee, Shihua He, Li Zhang, Jinghua Zhao, Khalida Shamim, Danielle Bougie, Wenwei Huang, Menghang Xia, Matthew D Hall, Donald Lo, Anton Simeonov, Christopher P Austin, Xiangguo Qiu, Hengli Tang, Wei Zheng
Biological activity-based modeling identifies antiviral leads against SARS-CoV-2. Nature biotechnology 39 (6) (2021)
Kirill Gorshkov, Desarey Morales Vasquez, Kevin Chiem, Chengjin Ye, Bruce Nguyen Tran, Juan Carlos de la Torre, Thomas Moran, Catherine Z Chen, Luis Martinez-Sobrido, Wei Zheng
A SARS-CoV-2 nucleocapsid protein TR-FRET assay amenable to high-throughput screening. bioRxiv : the preprint server for biology (2021)
Jing Li, Ruiqin Wu, Mingo M H Yung, Jing Sun, Zhuqing Li, Hai Yang, Yi Zhang, Stephanie S Liu, Annie N Y Cheung, Hextan Y S Ngan, John C Braisted, Wei Zheng, Huiqiang Wei, Yingtang Gao, Peter Nemes, Huadong Pei, David W Chan, Yiliang Li, Wenge Zhu
SENP1-mediated deSUMOylation of JAK2 regulates its kinase activity and platinum drug resistance. Cell death & disease 12 (4) (2021)
Wei Zhu, Catherine Z Chen, Kirill Gorshkov, Miao Xu, Donald C Lo, Wei Zheng
RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery. SLAS discovery : advancing life sciences R & D 25 (10) (2020)
Angela Johana Espejo-Mojica, Edwin Alexander Rodriguez-López, Rong Li, Wei Zheng, Carlos Javier Alméciga-Díaz, Cindy Dulcey-Sepúlveda, Germán Combariza, Luis A Barrera
Human recombinant lysosomal β-Hexosaminidases produced in Pichia pastoris efficiently reduced lipid accumulation in Tay-Sachs fibroblasts. American journal of medical genetics. Part C, Seminars in medical genetics 184 (4) (2020)
Kirill Gorshkov, Manisha Pradhan, Miao Xu, Shu Yang, Emily M Lee, Catherine Z Chen, Min Shen, Wei Zheng
Cell-Based No-Wash Fluorescence Assays for Compound Screens Using a Fluorescence Cytometry Plate Reader. The Journal of pharmacology and experimental therapeutics 374 (3) (2020)
Junjie Xu, Lin Ji, Yuelong Liang, Zhe Wan, Wei Zheng, Xiaomin Song, Kirill Gorshkov, Qiming Sun, Hui Lin, Xueyong Zheng, Jiang Chen, Ren-An Jin, Xiao Liang, Xiujun Cai
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1. Signal transduction and targeted therapy 5 (1) (2020)
Qi Zhang, Catherine Zhengzheng Chen, Manju Swaroop, Miao Xu, Lihui Wang, Juhyung Lee, Amy Qiu Wang, Manisha Pradhan, Natalie Hagen, Lu Chen, Min Shen, Zhiji Luo, Xin Xu, Yue Xu, Wenwei Huang, Wei Zheng, Yihong Ye
Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro. Cell discovery 6 (1) (2020)
Kirill Gorshkov, Amy Q Wang, Wei Sun, Ethan Fisher, Marta Frigeni, Marc Singleton, Natasha Thorne, Bradley Class, Wenwei Huang, Nicola Longo, Minh-Ha T Do, Elizabeth A Ottinger, Xin Xu, Wei Zheng
Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts. Pharmacology research & perspectives 7 (6) (2020)
Kirill Gorshkov, Catherine Z Chen, Robert Bostwick, Lynn Rasmussen, Bruce Nguyen Tran, Yu-Shan Cheng, Miao Xu, Manisha Pradhan, Mark J Henderson, Wei Zhu, Eunkeu Oh, Kimihiro Susumu, Mason Wolak, Khalida Shamim, Wenwei Huang, Xin Hu, Min Shen, Carleen Klumpp-Thomas, Zina Itkin, Paul Shinn, Juan Carlos de la Torre, Anton Simeonov, Sam G Michael, Matthew D Hall, Donald C Lo, Wei Zheng
The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules. ACS infectious diseases 7 (6) (2020)
Yu-Shan Cheng, Shu Yang, Junjie Hong, Rong Li, Jeanette Beers, Jizhong Zou, Wenwei Huang, Wei Zheng
Modeling CNS Involvement in Pompe Disease Using Neural Stem Cells Generated from Patient-Derived Induced Pluripotent Stem Cells. Cells 10 (1) (2020)
Xinyuan Wang, Fei Ye, Zhexing Wen, Ziyuan Guo, Chuan Yu, Wei-Kai Huang, Francisca Rojas Ringeling, Yijing Su, Wei Zheng, Guomin Zhou, Kimberly M Christian, Hongjun Song, Mingjie Zhang, Guo-Li Ming
Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Molecular psychiatry 26 (4) (2019)
Sheng Dai, Shu Yang, Xin Hu, Wei Sun, Gregory Tawa, Wenge Zhu, Aaron D Schimmer, Chao He, Bingliang Fang, Hongbo Zhu, Wei Zheng
17-Hydroxy Wortmannin Restores TRAIL's Response by Ameliorating Increased Beclin 1 Level and Autophagy Function in TRAIL-Resistant Colon Cancer Cells. Molecular cancer therapeutics 18 (7) (2019)
Kevin J Frankowski, Chen Wang, Samarjit Patnaik, Frank J Schoenen, Noel T Southall, Dandan Li, Yaroslav Teper, Wei Sun, Irawati Kandela, Deqing Hu, Christopher Dextras, Zachary Knotts, Yansong Bian, John Norton, Steve Titus, Marzena A Lewandowska, Yiping Wen, Katherine I Farley, Lesley Mathews Griner, Jamey Sultan, Zhaojing Meng, Ming Zhou, Tomas Vilimas, Astin S Powers, Serguei Kozlov, Kunio Nagashima, Humair S Quadri, Min Fang, Charles Long, Ojus Khanolkar, Warren Chen, Jinsol Kang, Helen Huang, Eric Chow, Esthermanya Goldberg, Coral Feldman, Romi Xi, Hye Rim Kim, Gary Sahagian, Susan J Baserga, Andrew Mazar, Marc Ferrer, Wei Zheng, Ali Shilatifard, Jeffrey Aube, Rushikesh Sable, Juan Jose Marugan, Sui Huang
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Science translational medicine 10 (441) (2019)
Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M H Yung, Jing Sun, Jing Li, Chi Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S Liu, Annie N Y Cheung, Hextan Yuen-Sheung Ngan, David W Chan, Wei Zheng, Wenge Zhu
ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (19) (2019)
Ni Sima, Rong Li, Wei Huang, Miao Xu, Jeanette Beers, Jizhong Zou, Steven Titus, Elizabeth A Ottinger, Juan J Marugan, Xing Xie, Wei Zheng
Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses. Orphanet journal of rare diseases 13 (1) (2018)
Shu Yang, Miao Xu, Emily M Lee, Kirill Gorshkov, Sergey A Shiryaev, Shihua He, Wei Sun, Yu-Shan Cheng, Xin Hu, Anil Mathew Tharappel, Billy Lu, Antonella Pinto, Chen Farhy, Chun-Teng Huang, Zirui Zhang, Wenjun Zhu, Yuying Wu, Yi Zhou, Guang Song, Heng Zhu, Khalida Shamim, Carles Martínez-Romero, Adolfo García-Sastre, Richard A Preston, Dushyantha T Jayaweera, Ruili Huang, Wenwei Huang, Menghang Xia, Anton Simeonov, Guo-Li Ming, Xiangguo Qiu, Alexey V Terskikh, Hengli Tang, Hongjun Song, Wei Zheng
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell discovery 4 (2018)
Mylinh Vu, Rong Li, Amanda Baskfield, Billy Lu, Atena Farkhondeh, Kirill Gorshkov, Omid Motabar, Jeanette Beers, Guokai Chen, Jizhong Zou, Angela J Espejo-Mojica, Alexander Rodríguez-López, Carlos J Alméciga-Díaz, Luis A Barrera, Xuntian Jiang, Daniel S Ory, Juan J Marugan, Wei Zheng
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease. Orphanet journal of rare diseases 13 (1) (2018)
Venkatesh Krishnan, Yanfei L Ma, Catherine Z Chen, Natasha Thorne, Heather Bullock, Gregory Tawa, Christy Javella-Cauley, Shaoyou Chu, Weiming Li, Wayne Kohn, Mary D Adrian, Charles Benson, Lifei Liu, Masahiko Sato, Wei Zheng, Andre M Pilon, N Nora Yang, Henry U Bryant
Repurposing a novel parathyroid hormone analogue to treat hypoparathyroidism. British journal of pharmacology 175 (2) (2017)
Francis Aguisanda, Charles D Yeh, Catherine Z Chen, Rong Li, Jeanette Beers, Jizhong Zou, Natasha Thorne, Wei Zheng
Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics. Orphanet journal of rare diseases 12 (1) (2017)
Sheng Dai, Andrés E Dulcey, Xin Hu, Christopher A Wassif, Forbes D Porter, Christopher P Austin, Daniel S Ory, Juan Marugan, Wei Zheng
Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy 13 (8) (2017)
Bill X Huang, Kenny Newcomer, Karl Kevala, Elena Barnaeva, Wei Zheng, Xin Hu, Samarjit Patnaik, Noel T Southall, Juan Marugan, Marc Ferrer, Hee-Yong Kim
Identification of 4-phenylquinolin-2(1H)-one as a specific allosteric inhibitor of Akt. Scientific reports 7 (1) (2017)
Elma Aflaki, Daniel K Borger, Nima Moaven, Barbara K Stubblefield, Steven A Rogers, Samarjit Patnaik, Frank J Schoenen, Wendy Westbroek, Wei Zheng, Patricia Sullivan, Hideji Fujiwara, Rohini Sidhu, Zayd M Khaliq, Grisel J Lopez, David S Goldstein, Daniel S Ory, Juan Marugan, Ellen Sidransky
A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism. The Journal of neuroscience : the official journal of the Society for Neuroscience 36 (28) (2017)
Wei Zheng, Wei Sun, Anton Simeonov
Drug repurposing screens and synergistic drug-combinations for infectious diseases. British journal of pharmacology 175 (2) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Wei Zheng