Zhiqiang An

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 77

Top Venues

Nature communications

PLoS pathogens

NPJ vaccines

Expert opinion on investigational drugs

University of Texas Health Science Center at Houston

University of Kentucky (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Texas Health Science Center at Houston

United States

Director :: The Texas Therapeutics Institute

The Universty of Texas Health Science Center at Houston

United States

Professor :: The Brown Foundation Institute of Molecular Medicine

Epitomics, Inc.

United States

Chief Scientific Officer

Merck Research Laboratories

United States

Director :: Vaccines & Biologics Research

Merck Research Laboratories

United States

Senior Research Fellow :: Vaccines & Biologics Research

Merck Research Rahway

United States

Research Fellow :: Natural products drug discovery

Millenium Pharmaceuticals, Inc.

United States

Scientist

University of Wisconsin - Madison

United States

Post-doctoral scholar, Microbial genetics :: Plant pathology

University of Wisconsin - Madison

United States

Post-doctoral scholar, Microbial genetics :: Biomolecular Chemistry

University of Kentucky

United States

Post-doctoral scholar, Microbial genetics :: Plant Biology

Education History

University of Kentucky

United States

PHD :: Plant Pathology

China Agricultural University

China

MSC :: Biology

Shanxi Agricultural University

China

BSC :: Biology

Publications

Anjali Geethadevi, Zhiqiang Ku, Shirng-Wern Tsaih, Deepak Parashar, Ishaque P Kadamberi, Wei Xiong, Hui Deng, Jasmine George, Sudhir Kumar, Sonam Mittal, Ningyan Zhang, Sunila Pradeep, Zhiqiang An, Pradeep Chaluvally-Raghavan
Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer. NPJ precision oncology 8 (1) (2024)
Ryan Huang, Xiaoye Liu, Jaehyup Kim, Hui Deng, Mi Deng, Xun Gui, Heyu Chen, Guojin Wu, Wei Xiong, Jingjing Xie, Cheryl M Lewis, Jade Homsi, Xing Yang, Chengcheng Zhang, Yubo He, Qi Lou, Caroline Smith, Samuel John, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
LILRB3 Supports Immunosuppressive Activity of Myeloid Cells and Tumor Development. Cancer immunology research 12 (3) (2024)
Ryan Huang, Xiaoye Liu, Jaehyup Kim, Hui Deng, Mi Deng, Xun Gui, Heyu Chen, Guojin Wu, Wei Xiong, Jingjing Xie, Cheryl M Lewis, Jade Homsi, Xing Yang, Chengcheng Zhang, Yubo He, Qi Lou, Caroline Smith, Samuel John, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
LILRB3 Supports Immunosuppressive Activity of Myeloid Cells and Tumor Development. Cancer immunology research 12 (3) (2024)
Xiaohua Ye, David J H Shih, Zhiqiang Ku, Junping Hong, Diane F Barrett, Richard E Rupp, Ningyan Zhang, Tong-Ming Fu, W Jim Zheng, Zhiqiang An
Transcriptional signature of durable effector T cells elicited by a replication defective HCMV vaccine. NPJ vaccines 9 (1) (2024)
Alexander H Flannery, Dawei Bu, Madison Botkins, Fabiola Gianella, Ningyan Zhang, Zhiqiang An, Orson W Moe, Jan-Bernd Funcke, Javier A Neyra
Endotrophin as a Biomarker for Severe Acute Kidney Injury and Major Adverse Kidney Events. Kidney360 5 (8) (2024)
Hsuan-Yuan Sherry Wang, Leike Li, Cody S Nelson, Richard Barfield, Sarah M Valencia, Cliburn Chan, Hiromi Muramatsu, Paulo J C Lin, Norbert Pardi, Zhiqiang An, Drew Weissman, Sallie R Permar
Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth. NPJ vaccines 9 (1) (2024)
Xiaohua Ye, David J H Shih, Zhiqiang Ku, Junping Hong, Diane F Barrett, Richard E Rupp, Ningyan Zhang, Tong-Ming Fu, W Jim Zheng, Zhiqiang An
Transcriptional signature of durable effector T cells elicited by a replication defective HCMV vaccine. NPJ vaccines 9 (1) (2024)
Hsuan-Yuan Sherry Wang, Leike Li, Cody S Nelson, Richard Barfield, Sarah M Valencia, Cliburn Chan, Hiromi Muramatsu, Paulo J C Lin, Norbert Pardi, Zhiqiang An, Drew Weissman, Sallie R Permar
Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth. NPJ vaccines 9 (1) (2024)
Anjali Geethadevi, Zhiqiang Ku, Shirng-Wern Tsaih, Deepak Parashar, Ishaque P Kadamberi, Wei Xiong, Hui Deng, Jasmine George, Sudhir Kumar, Sonam Mittal, Ningyan Zhang, Sunila Pradeep, Zhiqiang An, Pradeep Chaluvally-Raghavan
Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer. NPJ precision oncology 8 (1) (2024)
Hsuan-Yuan Sherry Wang, Leike Li, Cody S Nelson, Richard Barfield, Sarah M Valencia, Cliburn Chan, Hiromi Muramatsu, Paulo J C Lin, Norbert Pardi, Zhiqiang An, Drew Weissman, Sallie R Permar
Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth. NPJ vaccines 9 (1) (2024)
Alexander H Flannery, Dawei Bu, Madison Botkins, Fabiola Gianella, Ningyan Zhang, Zhiqiang An, Orson W Moe, Jan-Bernd Funcke, Javier A Neyra
Endotrophin as a Biomarker for Severe Acute Kidney Injury and Major Adverse Kidney Events. Kidney360 5 (8) (2024)
Alexander H Flannery, Dawei Bu, Madison Botkins, Fabiola Gianella, Ningyan Zhang, Zhiqiang An, Orson W Moe, Jan-Bernd Funcke, Javier A Neyra
Endotrophin as a Biomarker for Severe Acute Kidney Injury and Major Adverse Kidney Events. Kidney360 (2024)
Ryan Huang, Xiaoye Liu, Jaehyup Kim, Hui Deng, Mi Deng, Xun Gui, Heyu Chen, Guojin Wu, Wei Xiong, Jingjing Xie, Cheryl M Lewis, Jade Homsi, Xing Yang, Chengcheng Zhang, Yubo He, Qi Lou, Caroline Smith, Samuel John, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
LILRB3 Supports Immunosuppressive Activity of Myeloid Cells and Tumor Development. Cancer immunology research 12 (3) (2024)
Anjali Geethadevi, Zhiqiang Ku, Shirng-Wern Tsaih, Deepak Parashar, Ishaque P Kadamberi, Wei Xiong, Hui Deng, Jasmine George, Sudhir Kumar, Sonam Mittal, Ningyan Zhang, Sunila Pradeep, Zhiqiang An, Pradeep Chaluvally-Raghavan
Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer. NPJ precision oncology 8 (1) (2024)
Anjali Geethadevi, Zhiqiang Ku, Shirng-Wern Tsaih, Deepak Parashar, Ishaque P Kadamberi, Wei Xiong, Hui Deng, Jasmine George, Sudhir Kumar, Sonam Mittal, Ningyan Zhang, Sunila Pradeep, Zhiqiang An, Pradeep Chaluvally-Raghavan
Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer. NPJ precision oncology 8 (1) (2024)
Hsuan-Yuan Sherry Wang, Leike Li, Cody S Nelson, Richard Barfield, Sarah M Valencia, Cliburn Chan, Hiromi Muramatsu, Paulo J C Lin, Norbert Pardi, Zhiqiang An, Drew Weissman, Sallie R Permar
Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth. NPJ vaccines 9 (1) (2024)
Ryan Huang, Xiaoye Liu, Jaehyup Kim, Hui Deng, Mi Deng, Xun Gui, Heyu Chen, Guojin Wu, Wei Xiong, Jingjing Xie, Cheryl M Lewis, Jade Homsi, Xing Yang, Chengcheng Zhang, Yubo He, Qi Lou, Caroline Smith, Samuel John, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
LILRB3 Supports Immunosuppressive Activity of Myeloid Cells and Tumor Development. Cancer immunology research 12 (3) (2024)
Xiaohua Ye, David J H Shih, Zhiqiang Ku, Junping Hong, Diane F Barrett, Richard E Rupp, Ningyan Zhang, Tong-Ming Fu, W Jim Zheng, Zhiqiang An
Transcriptional signature of durable effector T cells elicited by a replication defective HCMV vaccine. NPJ vaccines 9 (1) (2024)
Ryan Huang, Xiaoye Liu, Jaehyup Kim, Hui Deng, Mi Deng, Xun Gui, Heyu Chen, Guojin Wu, Wei Xiong, Jingjing Xie, Cheryl M Lewis, Jade Homsi, Xing Yang, Chengcheng Zhang, Yubo He, Qi Lou, Caroline Smith, Samuel John, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
LILRB3 Supports Immunosuppressive Activity of Myeloid Cells and Tumor Development. Cancer immunology research 12 (3) (2024)
Zhuan Zhang, Gerald F Bills, Zhiqiang An
Advances in the treatment of invasive fungal disease. PLoS pathogens 19 (5) (2023)
Zhuan Zhang, Gerald F Bills, Zhiqiang An
Advances in the treatment of invasive fungal disease. PLoS pathogens 19 (5) (2023)
Zhuan Zhang, Gerald F Bills, Zhiqiang An
Advances in the treatment of invasive fungal disease. PLoS pathogens 19 (5) (2023)
Joshua W Morse, Margarita Rios, John Ye, Adan Rios, Cheng Cheng Zhang, Naval G Daver, Courtney D D DiNardo, Ningyan Zhang, Zhiqiang An
Antibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets. Expert opinion on investigational drugs 32 (2) (2023)
Zhuan Zhang, Gerald F Bills, Zhiqiang An
Advances in the treatment of invasive fungal disease. PLoS pathogens 19 (5) (2023)
Christopher J LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K Sood
Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nature communications 14 (1) (2023)
Joshua W Morse, Margarita Rios, John Ye, Adan Rios, Cheng Cheng Zhang, Naval G Daver, Courtney D D DiNardo, Ningyan Zhang, Zhiqiang An
Antibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets. Expert opinion on investigational drugs 32 (2) (2023)
Christopher J LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K Sood
Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nature communications 14 (1) (2023)
Sarah M Valencia, Eric Rochat, Melissa J Harnois, Maria Dennis, Helen S Webster, Bhavna Hora, Amit Kumar, Hsuan-Yuan Sherry Wang, Leike Li, Daniel Freed, Ningyan Zhang, Zhiqiang An, Dai Wang, Sallie R Permar
Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection. NPJ vaccines 8 (1) (2023)
Joshua W Morse, Margarita Rios, John Ye, Adan Rios, Cheng Cheng Zhang, Naval G Daver, Courtney D D DiNardo, Ningyan Zhang, Zhiqiang An
Antibody Therapies for the Treatment of Acute Myeloid Leukemia: Exploring Current and Emerging Therapeutic Targets. Expert opinion on investigational drugs (2023)
Junquan Liu, Huai-Chin Chiang, Wei Xiong, Victor Laurent, Samuel C Griffiths, Jasmin Dülfer, Hui Deng, Xiujie Sun, Y Whitney Yin, Wenliang Li, Laurent P Audoly, Zhiqiang An, Thomas Schürpf, Rong Li, Ningyan Zhang
A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer. Journal for immunotherapy of cancer 11 (6) (2023)
Shangang Zhao, Qian Lin, Wei Xiong, Li Li, Leon G Straub, Dinghong Zhang, Rizaldy C Zapata, Qingzhang Zhu, Xue-Nan Sun, Zhuzhen Zhang, Jan-Bernd Funcke, Chao Li, Shiuhwei Chen, Yi Zhu, Nisi Jiang, Guannan Li, Ziying Xu, Steven C Wyler, May-Yun Wang, Juli Bai, Xianlin Han, Christine M Kusminski, Ningyan Zhang, Zhiqiang An, Joel K Elmquist, Olivia Osborn, Chen Liu, Jan-Bernd Funcke
Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders. Science translational medicine 15 (723) (2023)
Joshua W Morse, Margarita Rios, John Ye, Adan Rios, Cheng Cheng Zhang, Naval G Daver, Courtney D D DiNardo, Ningyan Zhang, Zhiqiang An
Antibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets. Expert opinion on investigational drugs 32 (2) (2023)
Christopher J LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K Sood
Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nature communications 14 (1) (2023)
Zhuan Zhang, Gerald F Bills, Zhiqiang An
Advances in the treatment of invasive fungal disease. PLoS pathogens 19 (5) (2023)
Joshua W Morse, Xun Gui, Mi Deng, Ryan Huang, Xiaohua Ye, Peng Zhao, Xuejun Fan, Wei Xiong, Chengcheng Zhang, Ningyan Zhang, Zhiqiang An
Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML. Antibody therapeutics 7 (1) (2023)
Joshua W Morse, Xun Gui, Mi Deng, Ryan Huang, Xiaohua Ye, Peng Zhao, Xuejun Fan, Wei Xiong, Chengcheng Zhang, Ningyan Zhang, Zhiqiang An
Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML. Antibody therapeutics 7 (1) (2023)
Christopher J LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K Sood
Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nature communications 14 (1) (2023)
Zhuan Zhang, Gerald F Bills, Zhiqiang An
Advances in the treatment of invasive fungal disease. PLoS pathogens 19 (5) (2023)
Ryan Huang, Xiaoye Liu, Jaehyup Kim, Hui Deng, Mi Deng, Xun Gui, Heyu Chen, Guojin Wu, Wei Xiong, Jingjing Xie, Cheryl M Lewis, Jade Homsi, Xing Yang, Chengcheng Zhang, Yubo He, Qi Lou, Caroline Smith, Samuel John, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
LILRB3 supports immunosuppressive activity of myeloid cells and tumor development. Cancer immunology research (2023)
Joshua W Morse, Margarita Rios, John Ye, Adan Rios, Cheng Cheng Zhang, Naval G Daver, Courtney D D DiNardo, Ningyan Zhang, Zhiqiang An
Antibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets. Expert opinion on investigational drugs 32 (2) (2023)
Joshua W Morse, Xun Gui, Mi Deng, Ryan Huang, Xiaohua Ye, Peng Zhao, Xuejun Fan, Wei Xiong, Chengcheng Zhang, Ningyan Zhang, Zhiqiang An
Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML. Antibody therapeutics 7 (1) (2023)
Joshua W Morse, Xun Gui, Mi Deng, Ryan Huang, Xiaohua Ye, Peng Zhao, Xuejun Fan, Wei Xiong, Chengcheng Zhang, Ningyan Zhang, Zhiqiang An
Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML. Antibody therapeutics 7 (1) (2023)
Joshua W Morse, Xun Gui, Mi Deng, Ryan Huang, Xiaohua Ye, Peng Zhao, Xuejun Fan, Wei Xiong, Chengcheng Zhang, Ningyan Zhang, Zhiqiang An
Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML. Antibody therapeutics 7 (1) (2023)
Joshua W Morse, Margarita Rios, John Ye, Adan Rios, Cheng Cheng Zhang, Naval G Daver, Courtney D D DiNardo, Ningyan Zhang, Zhiqiang An
Antibody Therapies for the Treatment of Acute Myeloid Leukemia: Exploring Current and Emerging Therapeutic Targets. Expert opinion on investigational drugs (2023)
Joshua W Morse, Margarita Rios, John Ye, Adan Rios, Cheng Cheng Zhang, Naval G Daver, Courtney D D DiNardo, Ningyan Zhang, Zhiqiang An
Antibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets. Expert opinion on investigational drugs (2023)
Christopher J LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K Sood
Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nature communications 14 (1) (2023)
Qun Yue, Jie Meng, Yue Qiu, Miaomiao Yin, Liwen Zhang, Weiping Zhou, Zhiqiang An, Zihe Liu, Qipeng Yuan, Wentao Sun, Chun Li, Huimin Zhao, István Molnár, Yuquan Xu, Shuobo Shi
A polycistronic system for multiplexed and precalibrated expression of multigene pathways in fungi. Nature communications 14 (1) (2023)
Zhiqiang Ku, Xuping Xie, Jian Qing Lin, Peng Gao, Bin Wu, Abbas El Sahili, Hang Su, Yang Liu, Xiaohua Ye, Eddie Yongjun Tan, Xin Li, Xuejun Fan, Boon Chong Goh, Wei Xiong, Hannah Boyd, Antonio E Muruato, Hui Deng, Hongjie Xia, Jing Zou, Birte K Kalveram, Vineet D Menachery, Ningyan Zhang, Julien Lescar, Pei-Yong Shi, Zhiqiang An
Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth. Nature communications 13 (1) (2022)
Summer Y Y Ha, Yasuaki Anami, Chisato M Yamazaki, Wei Xiong, Candice M Haase, Scott D Olson, Jangsoon Lee, Naoto Tada Ueno, Ningyan Zhang, Zhiqiang An, Kyoji Tsuchikama
An Enzymatically Cleavable Tripeptide Linker for Maximizing the Therapeutic Index of Antibody-Drug Conjugates. Molecular cancer therapeutics 21 (9) (2022)
Xuejun Fan, Zihao Yuan, Yueshui Zhao, Wei Xiong, Hao-Ching Hsiao, Rahmawati Pare, Jianmin Ding, Ahmad Almosa, Kai Sun, Songlin Zhang, Robert E Jordan, Cheok Song Lee, Zhiqiang An, Ningyan Zhang
Impairment of IgG Fc functions promotes tumor progression and suppresses NK cell antitumor actions. Communications biology 5 (1) (2022)
Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Zhiqiang Ku, Leike Li, Xiaoye Liu, Mi Deng, Hisashi Arase, Jay-Jiguang Zhu, Timothy Y Huang, Yingjun Zhao, Chengcheng Zhang, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang An
LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Molecular neurodegeneration 17 (1) (2022)
Mason Ruiz, Ningyan Zhang, Anil K Sood, Zhiqiang An
Antibody therapeutics for epithelial ovarian cancer. Expert opinion on biological therapy 22 (11) (2022)
Peng Zhao, Yuanzhong Xu, Xuejun Fan, Leike Li, Xin Li, Hisashi Arase, Qingchun Tong, Ningyan Zhang, Zhiqiang An
Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice. mAbs 14 (1) (2022)
Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Leike Li, Xin Li, Hisashi Arase, Yingjun Zhao, Wei Cao, Hui Zheng, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang An
A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease. Science translational medicine 14 (661) (2022)
Daniel Wrapp, Xiaohua Ye, Zhiqiang Ku, Hang Su, Harrison G Jones, Nianshuang Wang, Akaash K Mishra, Daniel C Freed, Fengsheng Li, Aimin Tang, Leike Li, Dabbu Kumar Jaijyan, Hua Zhu, Dai Wang, Tong Ming Fu, Ningyan Zhang, Zhiqiang An, Jason S Mclellan
Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Science advances 8 (10) (2022)
Yasuaki Anami, Wei Xiong, Aiko Yamaguchi, Chisato M Yamazaki, Ningyan Zhang, Zhiqiang An, Kyoji Tsuchikama
Homogeneous antibody-angiopep 2 conjugates for effective brain targeting. RSC advances 12 (6) (2022)
Jennifer A Jenks, Cody S Nelson, Hunter K Roark, Matthew L Goodwin, Robert F Pass, David I Bernstein, Emmanuel B Walter, Kathryn M Edwards, Dai Wang, Tong Ming Fu, Zhiqiang An, Cliburn Chan, Sallie R Permar
Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans. Science translational medicine 12 (568) (2021)
Ila Mishra, Clemens Duerrschmid, Zhiqiang Ku, Yang He, Wei Xie, Elizabeth Sabath Silva, Jennifer Hoffman, Wei Xin, Ningyan Zhang, Yong Xu, Zhiqiang An, Atul R Chopra
Asprosin-neutralizing antibodies as a treatment for metabolic syndrome. eLife 10 (2021)
Yang Liu, Jianying Liu, Kenneth S Plante, Jessica A Plante, Xuping Xie, Xianwen Zhang, Zhiqiang Ku, Zhiqiang An, Dionna Scharton, Craig Schindewolf, Steven G Widen, Vineet D Menachery, Pei-Yong Shi, Scott C Weaver
The N501Y spike substitution enhances SARS-CoV-2 infection and transmission. Nature (2021)
Guojin Wu, Yixiang Xu, Robbie D Schultz, Heyu Chen, Jingjing Xie, Mi Deng, Xiaoye Liu, Xun Gui, Samuel John, Zhigang Lu, Hisashi Arase, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2-cFLIP-NF-κB signaling axis. Nature cancer 2 (11) (2021)
Zhao Shan, Leike Li, Constance Lynn Atkins, Meng Wang, Yankai Wen, Jongmin Jeong, Nicolas F Moreno, Dechun Feng, Xun Gui, Ningyan Zhang, Chun Geun Lee, Jack A Elias, William M Lee, Bin Gao, Fong Wilson Lam, Zhiqiang An, Cynthia Ju
Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment. eLife 10 (2021)
Zhiqiang Ku, Xuping Xie, Edgar Davidson, Xiaohua Ye, Hang Su, Vineet D Menachery, Yize Li, Zihao Yuan, Xianwen Zhang, Antonio E Muruato, Ariadna Grinyo I Escuer, Breanna Tyrell, Kyle Doolan, Benjamin J Doranz, Daniel Wrapp, Paul F Bates, Jason S Mclellan, Susan R Weiss, Ningyan Zhang, Pei-Yong Shi, Zhiqiang An
Author Correction: Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape. Nature communications 12 (1) (2021)
Chisato M Yamazaki, Aiko Yamaguchi, Yasuaki Anami, Wei Xiong, Yoshihiro Otani, Jangsoon Lee, Naoto Tada Ueno, Ningyan Zhang, Zhiqiang An, Kyoji Tsuchikama
Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance. Nature communications 12 (1) (2021)
Xiujie Sun, Bogang Wu, Huai-Chin Chiang, Hui Deng, Xiaowen Zhang, Wei Xiong, Junquan Liu, Aaron M Rozeboom, Brent T Harris, Eline Blommaert, Antonio Gómez, Roderic Espin Garcia, Yufan Zhou, Payal Mitra, Madeleine Prevost, Deyi Zhang, Debarati Banik, Claudine Isaacs, Deborah Berry, Catherine Lai, Krysta Chaldekas, Patricia S Latham, Christine A Brantner, Anastas Popratiloff, Victor X Jin, Ningyan Zhang, Yanfen Hu, Miguel Angel Pujana, Tyler J Curiel, Zhiqiang An, Rong Li
Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. Nature 599 (7886) (2021)
Bryan A Johnson, Xuping Xie, Adam L Bailey, Birte Kalveram, Kumari G Lokugamage, Antonio Muruato, Jing Zou, Xianwen Zhang, Terry Juelich, Jennifer K Smith, Lihong Zhang, Nathen Bopp, Craig Schindewolf, Michelle Vu, Abigail Vanderheiden, Emma S Winkler, Daniele M Swetnam, Jessica A Plante, Patricia Aguilar, Kenneth S Plante, Vsevolod Popov, Benhur Lee, Scott C Weaver, Mehul S Suthar, Andrew L Routh, Ping Ren, Zhiqiang Ku, Zhiqiang An, Kari Debbink, Michael S Diamond, Pei-Yong Shi, Alexander N Freiberg, Vineet D Menachery
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis. Nature 591 (7849) (2021)
Hang Su, Xiaohua Ye, Daniel C Freed, Leike Li, Zhiqiang Ku, Wei Xiong, Peng Gao, Xinli Liu, Diana Montgomery, Weifeng Xu, Amy S Espeseth, Dai Wang, Ningning Ma, Tong-Ming Fu, Ningyan Zhang, Zhiqiang An
Potent Bispecific Neutralizing Antibody Targeting Glycoprotein B and the gH/gL/pUL128/130/131 Complex of Human Cytomegalovirus. Antimicrobial agents and chemotherapy 65 (3) (2021)
Zhiqiang Ku, Xuping Xie, Paul R Hinton, Xinli Liu, Xiaohua Ye, Antonio E Muruato, Dean C Ng, Sujit Biswas, Jing Zou, Yang Liu, Deepal Pandya, Vineet D Menachery, Sachi Rahman, Yu-An Cao, Hui Deng, Wei Xiong, Kevin B Carlin, Junquan Liu, Hang Su, Elizabeth J Haanes, Bruce A Keyt, Ningyan Zhang, Stephen F Carroll, Pei-Yong Shi, Zhiqiang An
Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants. Nature 595 (7869) (2021)
Mi Deng, Heyu Chen, Xiaoye Liu, Ryan Huang, Yubo He, Byounggyu Yoo, Jingjing Xie, Samuel John, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
Leukocyte immunoglobulin-like receptor subfamily B: therapeutic targets in cancer. Antibody therapeutics 4 (1) (2021)
Zhiqiang Ku, Xuping Xie, Edgar Davidson, Xiaohua Ye, Hang Su, Vineet D Menachery, Yize Li, Zihao Yuan, Xianwen Zhang, Antonio E Muruato, Ariadna Grinyo I Escuer, Breanna Tyrell, Kyle Doolan, Benjamin J Doranz, Daniel Wrapp, Paul F Bates, Jason S Mclellan, Susan R Weiss, Ningyan Zhang, Pei-Yong Shi, Zhiqiang An
Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape. Nature communications 12 (1) (2021)
Leike Li, Daniel C Freed, Yaping Liu, Fengsheng Li, Diane F Barrett, Wei Xiong, Xiaohua Ye, Stuart P Adler, Richard E Rupp, Dai Wang, Ningyan Zhang, Tong-Ming Fu, Zhiqiang An
A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial. NPJ vaccines 6 (1) (2021)
Zihao Yuan, Xuejun Fan, Jay-Jiguang Zhu, Tong Ming Fu, Jiaqian Wu, Hua Xu, Ningyan Zhang, Zhiqiang An, Wenjin Jim Zheng
Presence of complete murine viral genome sequences in patient-derived xenografts. Nature communications 12 (1) (2021)
Nan Lan, Bruno Perlatti, Daniel J Kvitek, Philipp Wiemann, Colin J B Harvey, Jens Frisvad, Zhiqiang An, Gerald F Bills
Acrophiarin (antibiotic S31794/F-1) from Penicillium arenicola shares biosynthetic features with both Aspergillus- and Leotiomycete-type echinocandins. Environmental microbiology 22 (6) (2020)
Xiaohua Ye, Hang Su, Daniel Wrapp, Daniel C Freed, Fengsheng Li, Zihao Yuan, Aimin Tang, Leike Li, Zhiqiang Ku, Wei Xiong, Dabbu Jaijyan, Hua Zhu, Dai Wang, Jason S Mclellan, Ningyan Zhang, Tong Ming Fu, Zhiqiang An
Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step. PLoS pathogens 16 (8) (2020)
Xiaohua Ye, Xun Gui, Daniel C Freed, Zhiqiang Ku, Leike Li, Yuanzhi Chen, Wei Xiong, Xuejun Fan, Hang Su, Xi He, Richard R Rustandi, John W Loughney, Ningning Ma, Amy S Espeseth, Jian Liu, Hua Zhu, Dai Wang, Ningyan Zhang, Tong Ming Fu, Zhiqiang An
Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection. PLoS pathogens 15 (7) (2019)
Nan Lan, Qun Yue, Zhiqiang An, Gerald F Bills
Apc.LaeA and Apc.VeA of the velvet complex govern secondary metabolism and morphological development in the echinocandin-producing fungus Aspergillus pachycristatus. Journal of industrial microbiology & biotechnology 47 (1) (2019)
Leike Li, Weixu Meng, Melanie Horton, Daniel R DiStefano, Elizabeth A Thoryk, Jennifer M Pfaff, Qihui Wang, Georgina T Salazar, Trevor Barnes, Benjamin J Doranz, Andrew J Bett, Danilo R Casimiro, Kalpit A Vora, Zhiqiang An, Ningyan Zhang
Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes. PLoS pathogens 15 (6) (2019)
Hao-Ching Hsiao, Xuejun Fan, Robert E Jordan, Ningyan Zhang, Zhiqiang An
Proteolytic single hinge cleavage of pertuzumab impairs its Fc effector function and antitumor activity in vitro and in vivo. Breast cancer research : BCR 20 (1) (2018)

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Zhiqiang An