Adam McCluskey

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 39

Top Venues

ChemMedChem

RSC medicinal chemistry

Nature communications

Antibiotics (Basel, Switzerland)

The University of Strathclyde (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

The University of Strathclyde - Nov 04 1988

United Kingdom

PHD :: Pure and Applied Chemistry

Publications

Nicholas S O'Brien, Jayne Gilbert, Adam McCluskey, Jennette A Sakoff
2,3-Dihydroquinazolin-4(1 H )-ones and quinazolin-4(3 H )-ones as broad-spectrum cytotoxic agents and their impact on tubulin polymerisation. RSC medicinal chemistry 15 (5) (2024)
Nicholas S O'Brien, Jayne Gilbert, Adam McCluskey, Jennette A Sakoff
2,3-Dihydroquinazolin-4(1 H )-ones and quinazolin-4(3 H )-ones as broad-spectrum cytotoxic agents and their impact on tubulin polymerisation. RSC medicinal chemistry 15 (5) (2024)
Jayden Sterling, Jennifer R Baker, Adam McCluskey, Lenka Munoz
Systematic literature review reveals suboptimal use of chemical probes in cell-based biomedical research. Nature communications 14 (1) (2023)
Kathleen M Wright, Michael C Bowyer, Adam McCluskey, Clovia I Holdsworth
Molecular Imprinting of Benzylpiperazine: A Comparison of the Self-Assembly and Semi-Covalent Approaches. International journal of molecular sciences 24 (6) (2023)
Kathleen M Wright, Michael C Bowyer, Adam McCluskey, Clovia I Holdsworth
Molecular Imprinting of Benzylpiperazine: A Comparison of the Self-Assembly and Semi-Covalent Approaches. International journal of molecular sciences 24 (6) (2023)
Jufeng Sun, Jennifer R Baker, Cecilia C Russell, Hong Ngoc Thuy Pham, Chloe D Goldsmith, Peter J Cossar, Jennette A Sakoff, Christopher J Scarlett, Adam McCluskey
Novel piperazine-1,2,3-triazole leads for the potential treatment of pancreatic cancer. RSC medicinal chemistry 14 (11) (2023)
Luke R Odell, Nigel C Jones, Ngoc Chau, Mark J Robertson, Joseph I Ambrus, Fiona M Deane, Kelly A Young, Ainslie Whiting, Jing Xue, Kate Prichard, James A Daniel, Nick N Gorgani, Terence J O'Brien, Phillip J Robinson, Adam McCluskey
The sulfonadyns: a class of aryl sulfonamides inhibiting dynamin I GTPase and clathrin mediated endocytosis are anti-seizure in animal models. RSC medicinal chemistry 14 (8) (2023)
Kathleen M Wright, Michael C Bowyer, Adam McCluskey, Clovia I Holdsworth
Molecular Imprinting of Benzylpiperazine: A Comparison of the Self-Assembly and Semi-Covalent Approaches. International journal of molecular sciences 24 (6) (2023)
Hang Thi Nguyen, Henrietta Venter, Lucy Woolford, Kelly Young, Adam McCluskey, Sanjay Garg, Stephen W Page, Darren J Trott, Abiodun David Ogunniyi
Impact of a Novel Anticoccidial Analogue on Systemic Staphylococcus aureus Infection in a Bioluminescent Mouse Model. Antibiotics (Basel, Switzerland) 11 (1) (2022)
Qisi Zhang, Cyrille S Kounde, Milon Mondal, Jake L Greenfield, Jennifer R Baker, Sergei Kotelnikov, Mikhail Ignatov, Christopher P Tinworth, Leran Zhang, Daniel Conole, Elena De Vita, Dima Kozakov, Adam McCluskey, John D Harling, Matthew John Fuchter, Edward William Tate
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs). Chemical communications (Cambridge, England) 58 (78) (2022)
Jennifer R Baker, Peter J Cossar, Mark A T Blaskovich, Alysha G Elliott, Johannes Zuegg, Matthew A Cooper, Peter J Lewis, Adam McCluskey
Amino Alcohols as Potential Antibiotic and Antifungal Leads. Molecules (Basel, Switzerland) 27 (7) (2022)
Andrew J Stevens, Rebecca Abraham, Kelly A Young, Cecilia C Russell, Siobhann N McCluskey, Jennifer R Baker, Bertha Rusdi, Stephen W Page, Ryan O'Handley, Mark A O'Dea, Sam Abraham, Adam McCluskey
Antigiardial Activity of Novel Guanidine Compounds. ChemMedChem 17 (21) (2022)
Luke R Odell, Mark J Robertson, Kelly A Young, Andrew B McGeachie, Annie Quan, Phillip J Robinson, Adam McCluskey
Prodrugs of the Archetypal Dynamin Inhibitor Bis-T-22. ChemMedChem (2022)
Hongfei Pi, Henrietta Venter, Cecilia C Russell, Kelly A Young, Adam McCluskey, Stephen W Page, Abiodun David Ogunniyi, Darren J Trott
In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens. Antibiotics (Basel, Switzerland) 11 (10) (2022)
David T Stanton, Jennifer R Baker, Adam McCluskey, Stefan Paula
Development and interpretation of a QSAR model for in vitro breast cancer (MCF-7) cytotoxicity of 2-phenylacrylonitriles. Journal of computer-aided molecular design 35 (5) (2021)
Jennifer R Baker, Cecilia C Russell, Jayne Gilbert, Adam McCluskey, Jennette A Sakoff
Amino alcohol acrylonitriles as broad spectrum and tumour selective cytotoxic agents. RSC medicinal chemistry 12 (6) (2021)
Luke R Odell, Ngoc Chau, Cecilia C Russell, Kelly A Young, Jayne Gilbert, Phillip J Robinson, Jennette A Sakoff, Adam McCluskey
Pyrimidyn-Based Dynamin Inhibitors as Novel Cytotoxic Agents. ChemMedChem (2021)
Hang Thi Nguyen, Lisa A O'Donovan, Henrietta Venter, Cecilia C Russell, Adam McCluskey, Stephen W Page, Darren J Trott, Abiodun David Ogunniyi
Comparison of Two Transmission Electron Microscopy Methods to Visualize Drug-Induced Alterations of Gram-Negative Bacterial Morphology. Antibiotics (Basel, Switzerland) 10 (3) (2021)
Jufeng Sun, Joey I Ambrus, Cecilia C Russell, Jennifer R Baker, Peter J Cossar, Melanie J Pirinen, Jennette A Sakoff, Christopher J Scarlett, Adam McCluskey
Targeting the S100A2-p53 Interaction with a Series of 3,5-Bis(trifluoromethyl)benzene Sulfonamides: Synthesis and Cytotoxicity. ChemMedChem 16 (18) (2021)
Jufeng Sun, Jennifer R Baker, Cecilia C Russell, Peter J Cossar, Hong Ngoc Thuy Pham, Jennette A Sakoff, Christopher J Scarlett, Adam McCluskey
Cytotoxic 1,2,3-Triazoles as Potential Leads Targeting the S100A2-p53 Complex: Synthesis and Cytotoxicity. ChemMedChem 16 (18) (2021)
Jennifer R Baker, Brett L Pollard, Andrew J S Lin, Jayne Gilbert, Stefan Paula, Xiao Zhu, Jennette A Sakoff, Adam McCluskey
Modelling and Phenotypic Screening of NAP-6 and 10-Cl-BBQ, AhR Ligands Displaying Selective Breast Cancer Cytotoxicity in Vitro. ChemMedChem 16 (9) (2021)
Cedric S Tremblay, Sung Kai Chiu, Jesslyn Saw, Hannah McCalmont, Veronique Litalien, Jacqueline Boyle, Stefan E Sonderegger, Ngoc Chau, Kathryn Evans, Loretta Cerruti, Jessica M Salmon, Adam McCluskey, Richard B Lock, Phillip J Robinson, Stephen M Jane, David J Curtis
Author Correction: Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells. Nature communications 12 (1) (2021)
Jufeng Sun, Cecilia C Russell, Christopher J Scarlett, Adam McCluskey
Small molecule inhibitors in pancreatic cancer. RSC medicinal chemistry 11 (2) (2020)
Cedric S Tremblay, Sung Kai Chiu, Jesslyn Saw, Hannah McCalmont, Veronique Litalien, Jacqueline Boyle, Stefan E Sonderegger, Ngoc Chau, Kathryn Evans, Loretta Cerruti, Jessica M Salmon, Adam McCluskey, Richard B Lock, Phillip J Robinson, Stephen M Jane, David J Curtis
Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells. Nature communications 11 (1) (2020)
Matthew G Alteen, Christina Gros, Richard W Meek, David A Cardoso, Jil A Busmann, Gontran Sangouard, Matthew C Deen, Hong-Yee Tan, David L Shen, Cecilia C Russell, Gideon J Davies, Phillip J Robinson, Adam McCluskey, David J Vocadlo
A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High-Throughput Screening: Application to O-GlcNAc Transferase. Angewandte Chemie (International ed. in English) 59 (24) (2020)
Jennifer R Baker, Cecilia C Russell, Jayne Gilbert, Jennette A Sakoff, Adam McCluskey
Amino Alcohol Acrylonitriles as Activators of the Aryl Hydrocarbon Receptor Pathway: An Unexpected MTT Phenotypic Screening Outcome. ChemMedChem 15 (6) (2020)
Lacey Hizartzidis, Jayne Gilbert, Christopher P Gordon, Jennette A Sakoff, Adam McCluskey
Synthesis and Cytotoxicity of Octahydroepoxyisoindole-7-carboxylic Acids and Norcantharidin-Amide Hybrids as Norcantharidin Analogues. ChemMedChem 14 (12) (2019)
Jennifer R Baker, Jennette A Sakoff, Adam McCluskey
The aryl hydrocarbon receptor (AhR) as a breast cancer drug target. Medicinal research reviews 40 (3) (2019)
Ahmed Al Otaibi, Fiona M Deane, Cecilia C Russell, Lacey Hizartzidis, Siobhann N McCluskey, Jennette A Sakoff, Adam McCluskey
A methanol and protic ionic liquid Ugi multicomponent reaction path to cytotoxic α-phenylacetamido amides. RSC advances 9 (14) (2019)
Melanie J Predebon, Danielle R Bond, Joshua S Brzozowski, Helen Jankowski, Fiona Deane, Mark Tarleton, Aron A Shaw, Adam McCluskey, Michael C Bowyer, Judith Weidenhofer, Christopher J Scarlett
The Bispidinone Derivative 3,7-Bis-[2-(S)-amino-3-(1H-indol-3-yl)-propionyl]-1,5-diphenyl-3,7-diazabicyclo[3.3.1]nonan-9-one Dihydrochloride Induces an Apoptosis-Mediated Cytotoxic Effect on Pancreatic Cancer Cells In Vitro. Molecules (Basel, Switzerland) 24 (3) (2019)
Cecilia C Russell, Andrew J Stevens, Kelly A Young, Jennifer R Baker, Siobhann N McCluskey, Manouchehr Khazandi, Hongfei Pi, Abiodun David Ogunniyi, Stephen W Page, Darren J Trott, Adam McCluskey
Discovery of 4,6-bis(2-((E)-benzylidene)hydrazinyl)pyrimidin-2-Amine with Antibiotic Activity. ChemistryOpen 8 (7) (2019)
Peter J Cossar, Peter J Lewis, Adam McCluskey
Protein-protein interactions as antibiotic targets: A medicinal chemistry perspective. Medicinal research reviews 40 (2) (2018)
Trieu N Trinh, Eileen A McLaughlin, Christopher P Gordon, Ilana R Bernstein, Victoria J Pye, Kate A Redgrove, Adam McCluskey
Small molecule Hedgehog pathway antagonists. Organic & biomolecular chemistry 15 (14) (2018)
Dane D Jensen, TinaMarie Lieu, Michelle L Halls, Nicholas A Veldhuis, Wendy L Imlach, Quynh N Mai, Daniel P Poole, Tim Quach, Luigi Aurelio, Joshua W Conner, Carmen Klein Herenbrink, Nicholas Barlow, Jamie S Simpson, Martin J Scanlon, Bimbil Graham, Adam McCluskey, Phillip J Robinson, Virginie Escriou, Romina Nassini, Serena Materazzi, Pierangelo Geppetti, Gareth A Hicks, Macdonald J Christie, Christopher J H Porter, Meritxell Canals, Nigel W Bunnett
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief. Science translational medicine 9 (392) (2018)
Cecilia C Russell, Andrew J Stevens, Hongfei Pi, Manouchehr Khazandi, Abiodun David Ogunniyi, Kelly A Young, Jennifer R Baker, Siobhann N McCluskey, Stephen W Page, Darren J Trott, Adam McCluskey
Gram-Positive and Gram-Negative Antibiotic Activity of Asymmetric and Monomeric Robenidine Analogues. ChemMedChem 13 (23) (2018)
Azadeh Ghods, Jayne Gilbert, Jennifer R Baker, Cecilia C Russell, Jennette A Sakoff, Adam McCluskey
A focused library synthesis and cytotoxicity of quinones derived from the natural product bolinaquinone. Royal Society open science 5 (4) (2018)
Jennifer R Baker, Jayne Gilbert, Stefan Paula, Xiao Zhu, Jennette A Sakoff, Adam McCluskey
Dichlorophenylacrylonitriles as AhR Ligands That Display Selective Breast Cancer Cytotoxicity in vitro. ChemMedChem 13 (14) (2018)
Peter J Cossar, Jennifer R Baker, Nicholas Cain, Adam McCluskey
In situ epoxide generation by dimethyldioxirane oxidation and the use of epichlorohydrin in the flow synthesis of a library of β-amino alcohols. Royal Society open science 5 (4) (2018)
Luke R Odell, Mohammed K Abdel-Hamid, Timothy A Hill, Ngoc Chau, Kelly A Young, Fiona M Deane, Jennette A Sakoff, Sofia Andersson, James A Daniel, Phillip J Robinson, Adam McCluskey
Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain. Journal of medicinal chemistry 60 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Adam McCluskey