Meritxell Canals

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Venues

ACS chemical neuroscience

Science signaling

The Journal of biological chemistry

British journal of pharmacology

University of Nottingham

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Nottingham Oct 01 2018

United Kingdom

Professor in Cellular Pharmacology

Monash University - Sep 14 2018

Australia

Monash Fellow, Lab Head :: Drug Discovery Biology

Publications

Owen Underwood, Sebastian Fritzwanker, Jaqueline Glenn, Nina Kathleen Blum, Arisbel Batista-Gondin, Julia Drube, Carsten Hoffmann, Stephen J Briddon, Stefan Schulz, Meritxell Canals
Key phosphorylation sites for robust β-arrestin2 binding at the MOR revisited. Communications biology 7 (1) (2024)
Meng-Hua M Tsai, Li Chen, Michael H Baumann, Meritxell Canals, Jonathan A Javitch, J Robert Lane, Lei Shi
In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling. ACS chemical neuroscience 15 (4) (2024)
Owen Underwood, Sebastian Fritzwanker, Jaqueline Glenn, Nina Kathleen Blum, Arisbel Batista-Gondin, Julia Drube, Carsten Hoffmann, Stephen J Briddon, Stefan Schulz, Meritxell Canals
Key phosphorylation sites for robust β-arrestin2 binding at the MOR revisited. Communications biology 7 (1) (2024)
Meng-Hua M Tsai, Li Chen, Michael H Baumann, Meritxell Canals, Jonathan A Javitch, J Robert Lane, Lei Shi
In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling. ACS chemical neuroscience (2024)
Meng-Hua M Tsai, Li Chen, Michael H Baumann, Meritxell Canals, Jonathan A Javitch, J Robert Lane, Lei Shi
In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling. ACS chemical neuroscience 15 (4) (2024)
Meng-Hua M Tsai, Li Chen, Michael H Baumann, Meritxell Canals, Jonathan A Javitch, J Robert Lane, Lei Shi
In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling. ACS chemical neuroscience 15 (4) (2024)
Owen Underwood, Raphael Silvanus Haider, Julie Sanchez, Meritxell Canals
Arrestin-centred interactions at the membrane and their conformational determinants. British journal of pharmacology (2024)
Meng-Hua M Tsai, Li Chen, Michael H Baumann, Meritxell Canals, Jonathan A Javitch, J Robert Lane, Lei Shi
In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling. ACS chemical neuroscience 15 (4) (2024)
Owen Underwood, Sebastian Fritzwanker, Jaqueline Glenn, Nina Kathleen Blum, Arisbel Batista-Gondin, Julia Drube, Carsten Hoffmann, Stephen J Briddon, Stefan Schulz, Meritxell Canals
Key phosphorylation sites for robust β-arrestin2 binding at the MOR revisited. Communications biology 7 (1) (2024)
Rob Hill, Julie Sanchez, Laura Lemel, Mirjana Antonijevic, Yselkla Hosking, Shailesh N Mistry, Andrew C Kruegel, Jonathan A Javitch, J Robert Lane, Meritxell Canals
Assessment of the potential of novel and classical opioids to induce respiratory depression in mice. British journal of pharmacology (2023)
Sebastian Dekkers, Dehan Comez, Noemi Karsai, Marta Arimont-Segura, Meritxell Canals, Birgit Caspar, Chris de Graaf, Laura E Kilpatrick, Rob Leurs, Barrie Kellam, Stephen J Hill, Stephen J Briddon, Michael J Stocks
Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3). ACS medicinal chemistry letters 15 (1) (2023)
Sebastian Dekkers, Dehan Comez, Noemi Karsai, Marta Arimont-Segura, Meritxell Canals, Birgit Caspar, Chris de Graaf, Laura E Kilpatrick, Rob Leurs, Barrie Kellam, Stephen J Hill, Stephen J Briddon, Michael J Stocks
Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3). ACS medicinal chemistry letters 15 (1) (2023)
Alessandro Bonifazi, Elizabeth Saab, Julie Sanchez, Antonina L Nazarova, Saheem A Zaidi, Khorshada Jahan, Vsevolod Katritch, Meritxell Canals, J Robert Lane, Amy Hauck Newman
Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D 3 (D 3 R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics. Journal of medicinal chemistry (2023)
Amanda Lillywhite, Stephen G Woodhams, Sara V Gonçalves, David J G Watson, Li Li, James J Burston, Peter R W Gowler, Meritxell Canals, David Andrew Walsh, Gareth J Hathway, Victoria Chapman
Anxiety enhances pain in a model of osteoarthritis and is associated with altered endogenous opioid function and reduced opioid analgesia. Pain reports 6 (4) (2022)
Rob Hill, Andrew C Kruegel, Jonathan A Javitch, J Robert Lane, Meritxell Canals
The respiratory depressant effects of mitragynine are limited by its conversion to 7-OH mitragynine. British journal of pharmacology 179 (14) (2022)
Alessandro Bonifazi, Francisco O Battiti, Julie Sanchez, Saheem A Zaidi, Eric Bow, Mariia Makarova, Jianjing Cao, Anver Basha Shaik, Agnieszka Sulima, Kenner C Rice, Vsevolod Katritch, Meritxell Canals, J Robert Lane, Amy Hauck Newman
Novel Dual-Target μ-Opioid Receptor and Dopamine D3 Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management. Journal of medicinal chemistry 64 (11) (2021)
Siyao Wang, Simon R Foster, Julie Sanchez, Leo Corcilius, Mark Larance, Meritxell Canals, Richard J Payne, Richard J Payne
Glycosylation Regulates N-Terminal Proteolysis and Activity of the Chemokine CCL14. ACS chemical biology 16 (6) (2021)
Alexander Gillis, Arisbel B Gondin, Andrea Kliewer, Julie Sanchez, Herman D Lim, Claudia Alamein, Preeti Manandhar, Marina J Santiago, Sebastian Fritzwanker, Frank Schmiedel, Timothy A Katte, Tristan A Reekie, Natasha L Grimsey, Michael Kassiou, Barrie Kellam, Cornelius Krasel, Michelle L Halls, Mark Connor, J Robert Lane, Stefan Schulz, Macdonald J Christie, Meritxell Canals
Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists. Science signaling 13 (625) (2020)
Cheng Huang, Simon R Foster, Anup D Shah, Oded Kleifeld, Meritxell Canals, Ralf Bernd Schittenhelm, Richard J Payne
Phosphoproteomic characterization of the signaling network resulting from activation of the chemokine receptor CCR2. The Journal of biological chemistry 295 (19) (2020)
Srgjan Civciristov, Cheng Huang, Bonan Liu, Elsa A Marquez, Arisbel B Gondin, Ralf Bernd Schittenhelm, Andrew M Ellisdon, Meritxell Canals, Michelle L Halls
Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks. The Journal of biological chemistry 294 (44) (2019)
Elke Miess, Arisbel B Gondin, Arsalan Yousuf, Ralph Steinborn, Nadja Mösslein, Yunshi Yang, Martin Göldner, Julia G Ruland, Moritz Bünemann, Cornelius Krasel, Macdonald J Christie, Michelle L Halls, Stefan Schulz, Meritxell Canals
Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization. Science signaling 11 (539) (2018)
Dane D Jensen, TinaMarie Lieu, Michelle L Halls, Nicholas A Veldhuis, Wendy L Imlach, Quynh N Mai, Daniel P Poole, Tim Quach, Luigi Aurelio, Joshua W Conner, Carmen Klein Herenbrink, Nicholas Barlow, Jamie S Simpson, Martin J Scanlon, Bimbil Graham, Adam McCluskey, Phillip J Robinson, Virginie Escriou, Romina Nassini, Serena Materazzi, Pierangelo Geppetti, Gareth A Hicks, Macdonald J Christie, Christopher J H Porter, Meritxell Canals, Nigel W Bunnett
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief. Science translational medicine 9 (392) (2018)
Srgjan Civciristov, Andrew M Ellisdon, Ryan Suderman, Cindy K Pon, Bronwyn A Evans, Oded Kleifeld, Steven J Charlton, William S Hlavacek, Meritxell Canals, Michelle L Halls
Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations. Science signaling 11 (551) (2018)
Jenni Hayward, Julie Sanchez, Andrew Perry, Cheng Huang, Manuel Rodriguez Valle, Meritxell Canals, Richard J Payne, Richard J Payne
Ticks from diverse genera encode chemokine-inhibitory evasin proteins. The Journal of biological chemistry 292 (38) (2017)
Zil E Huma, Julie Sanchez, Herman D Lim, Jessica L Bridgford, Cheng Huang, Bradyn J Parker, Jiann G Pazhamalil, Benjamin T Porebski, Kevin D G Pfleger, J Robert Lane, Meritxell Canals, Richard J Payne
Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2. Science signaling 10 (480) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Meritxell Canals