Christiane Neumann (Christian Klein, C Klein)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 73

Top Topics

Combination Therapy

Monoclonal Antibody

Dendritic Cells

Chronic Lymphocytic Leukemia

Top Venues

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Christiane Neumann, Ulrich Brinkmann, Janice M Reichert, Roland E Kontermann
The present and future of bispecific antibodies for cancer therapy. Nature reviews. Drug discovery 23 (4) (2024)
Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac B Woodhouse, Alexander Bujotzek, Christiane Neumann, Nicola Ternette
The physiological interactome of TCR-like antibody therapeutics in human tissues. Nature communications 15 (1) (2024)
Christiane Neumann, Ulrich Brinkmann, Janice M Reichert, Roland E Kontermann
The present and future of bispecific antibodies for cancer therapy. Nature reviews. Drug discovery (2024)
Solange Peters, Eric Angevin, Teresa Alonso Gordoa, Kristoffer Staal Rohrberg, Ignacio Melero Bermejo, Begona Mellado, Jose-Luis Perez-Gracia, Josep Tabernero, Celine Adessi, Christophe Boetsch, Carl Watson, Joseph Dal Porto, David Dejardin, Christopher Del Nagro, Valeria Nicolini, Stefan Evers, Christiane Neumann, Barbara Leutgeb, Pavel Pisa, Eva Rossmann, José Saro, Pablo Umaña, Jehad Charo, Volker Teichgräber, Neeltje Steeghs
Obinutuzumab Pretreatment as a Novel Approach to Mitigate Formation of Anti-Drug Antibodies Against Cergutuzumab Amunaleukin in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Christiane Neumann, Ulrich Brinkmann, Janice M Reichert, Roland E Kontermann
The present and future of bispecific antibodies for cancer therapy. Nature reviews. Drug discovery 23 (4) (2024)
Solange Peters, Eric Angevin, Teresa Alonso Gordoa, Kristoffer Staal Rohrberg, Ignacio Melero Bermejo, Begona Mellado, Jose-Luis Perez-Gracia, Josep Tabernero, Celine Adessi, Christophe Boetsch, Carl Watson, Joseph Dal Porto, David Dejardin, Christopher Del Nagro, Valeria Nicolini, Stefan Evers, Christiane Neumann, Barbara Leutgeb, Pavel Pisa, Eva Rossmann, José Saro, Pablo Umaña, Jehad Charo, Volker Teichgräber, Neeltje Steeghs
Obinutuzumab Pretreatment as a Novel Approach to Mitigate Formation of Anti-Drug Antibodies Against Cergutuzumab Amunaleukin in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Christiane Neumann, Ulrich Brinkmann, Janice M Reichert, Roland E Kontermann
The present and future of bispecific antibodies for cancer therapy. Nature reviews. Drug discovery 23 (4) (2024)
Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac B Woodhouse, Alexander Bujotzek, Christiane Neumann, Nicola Ternette
The physiological interactome of TCR-like antibody therapeutics in human tissues. Nature communications 15 (1) (2024)
Gerulf Hänel, Anne Schönle, Anne-Sophie Neumann, Daniel Nixdorf, Nora Philipp, Monika Sponheimer, Alexandra Leutbecher, Alica-Joana Emhardt, Giulia Magno, Veit L Bücklein, Jan Eckmann, Diana Dunshee, Vesna Kramar, Koorosh Korfi, Sara Colombetti, Pablo Umaña, Christiane Neumann, Marion Subklewe
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment. Leukemia 38 (2) (2024)
Gerulf Hänel, Anne Schönle, Anne-Sophie Neumann, Daniel Nixdorf, Nora Philipp, Monika Sponheimer, Alexandra Leutbecher, Alica-Joana Emhardt, Giulia Magno, Veit L Bücklein, Jan Eckmann, Diana Dunshee, Vesna Kramar, Koorosh Korfi, Sara Colombetti, Pablo Umaña, Christiane Neumann, Marion Subklewe
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment. Leukemia 38 (2) (2024)
Angela A Wang, Felix Luessi, Tradite Neziraj, Elisabeth Pössnecker, Michelle Zuo, Sinah Engel, Nicholas Hanuscheck, Alexandra Florescu, Eryn Bugbee, Xianjie Iris Ma, Fatima Rana, Dennis Lee, Lesley A Ward, Jens Kuhle, Johannes Himbert, Muriel Schraad, Erwin van Puijenbroek, Christiane Neumann, Eduard Urich, Valeria Ramaglia, Anne-Katrin Pröbstel, Frauke Zipp, Jennifer L Gommerman
B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans. Science translational medicine 16 (737) (2024)
Johannes Sam, Thomas Hofer, Christine Kuettel, Christina Claus, Jenny Thom, Sylvia Herter, Guy Georges, Koorosh Korfi, Martin Lechmann, Miro Julian Eigenmann, Daniel Marbach, Candice Jamois, Katharina Lechner, Sreenath M Krishnan, Brenda Gaillard, Joana Marinho, Sven Kronenberg, Leo Kunz, Sabine Wilson, Stefanie Briner, Samuel Gebhardt, Ahmet Varol, Birte Appelt, Valeria Nicolini, Dario Speziale, Miriam Bez, Esther Bommer, Jan Eckmann, Carina Hage, Florian Limani, Silvia Jenni, Anne Schoenle, Marine Le Clech, Jean-Baptiste Pierre Vallier, Sara Colombetti, Marina Bacac, Stephan Gasser, Christiane Neumann, Pablo Umaña
CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy. Blood 143 (21) (2024)
Gerulf Hänel, Anne Schönle, Anne-Sophie Neumann, Daniel Nixdorf, Nora Philipp, Monika Sponheimer, Alexandra Leutbecher, Alica-Joana Emhardt, Giulia Magno, Veit L Bücklein, Jan Eckmann, Diana Dunshee, Vesna Kramar, Koorosh Korfi, Sara Colombetti, Pablo Umaña, Christiane Neumann, Marion Subklewe
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment. Leukemia 38 (2) (2024)
Gerulf Hänel, Anne Schönle, Anne-Sophie Neumann, Daniel Nixdorf, Nora Philipp, Monika Sponheimer, Alexandra Leutbecher, Alica-Joana Emhardt, Giulia Magno, Veit L Bücklein, Jan Eckmann, Diana Dunshee, Vesna Kramar, Koorosh Korfi, Sara Colombetti, Pablo Umaña, Christiane Neumann, Marion Subklewe
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment. Leukemia 38 (2) (2024)
Gerulf Hänel, Anne Schönle, Anne-Sophie Neumann, Daniel Nixdorf, Nora Philipp, Monika Sponheimer, Alexandra Leutbecher, Alica-Joana Emhardt, Giulia Magno, Veit L Bücklein, Jan Eckmann, Diana Dunshee, Vesna Kramar, Koorosh Korfi, Sara Colombetti, Pablo Umaña, Christiane Neumann, Marion Subklewe
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment. Leukemia (2024)
Johannes Sam, Thomas Hofer, Christine Kuettel, Christina Claus, Jenny Thom, Sylvia Herter, Guy Georges, Koorosh Korfi, Martin Lechmann, Miro Julian Eigenmann, Daniel Marbach, Candice Jamois, Katharina Lechner, Sreenath M Krishnan, Brenda Gaillard, Joana Marinho, Sven Kronenberg, Leo Kunz, Sabine Wilson, Stefanie Briner, Samuel Gebhardt, Ahmet Varol, Birte Appelt, Valeria Nicolini, Dario Speziale, Miriam Bez, Esther Bommer, Jan Eckmann, Carina Hage, Florian Limani, Silvia Jenni, Anne Schoenle, Marine Le Clech, Jean-Baptiste Pierre Vallier, Sara Colombetti, Marina Bacac, Stephan Gasser, Christiane Neumann, Pablo Umaña
CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy. Blood 143 (21) (2024)
Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac B Woodhouse, Alexander Bujotzek, Christiane Neumann, Nicola Ternette
The physiological interactome of TCR-like antibody therapeutics in human tissues. Nature communications 15 (1) (2024)
Marlena Surowka, Christiane Neumann
A pivotal decade for bispecific antibodies? mAbs 16 (1) (2024)
Gerulf Hänel, Anne Schönle, Anne-Sophie Neumann, Daniel Nixdorf, Nora Philipp, Monika Sponheimer, Alexandra Leutbecher, Alica-Joana Emhardt, Giulia Magno, Veit L Bücklein, Jan Eckmann, Diana Dunshee, Vesna Kramar, Koorosh Korfi, Sara Colombetti, Pablo Umaña, Christiane Neumann, Marion Subklewe
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment. Leukemia 38 (2) (2024)
Marlena Surowka, Christiane Neumann
A pivotal decade for bispecific antibodies? mAbs 16 (1) (2024)
Marlena Surowka, Christiane Neumann
A pivotal decade for bispecific antibodies? mAbs 16 (1) (2024)
Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac B Woodhouse, Alexander Bujotzek, Christiane Neumann, Nicola Ternette
The physiological interactome of TCR-like antibody therapeutics in human tissues. Nature communications 15 (1) (2024)
Johannes Sam, Thomas Hofer, Christine Kuettel, Christina Claus, Jenny Thom, Sylvia Herter, Guy Georges, Koorosh Korfi, Martin Lechmann, Miro Julian Eigenmann, Daniel Marbach, Candice Jamois, Katharina Lechner, Sreenath M Krishnan, Brenda Gaillard, Joana Marinho, Sven Kronenberg, Leo Kunz, Sabine Wilson, Stefanie Briner, Samuel Gebhardt, Ahmet Varol, Birte Appelt, Valeria Nicolini, Dario Speziale, Miriam Bez, Esther Bommer, Jan Eckmann, Carina Hage, Florian Limani, Silvia Jenni, Anne Schoenle, Marine Le Clech, Jean-Baptiste Pierre Vallier, Sara Colombetti, Marina Bacac, Stephan Gasser, Christiane Neumann, Pablo Umaña
CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy. Blood 143 (21) (2024)
Gerulf Hänel, Anne Schönle, Anne-Sophie Neumann, Daniel Nixdorf, Nora Philipp, Monika Sponheimer, Alexandra Leutbecher, Alica-Joana Emhardt, Giulia Magno, Veit L Bücklein, Jan Eckmann, Diana Dunshee, Vesna Kramar, Koorosh Korfi, Sara Colombetti, Pablo Umaña, Christiane Neumann, Marion Subklewe
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment. Leukemia 38 (2) (2024)
Angela A Wang, Felix Luessi, Tradite Neziraj, Elisabeth Pössnecker, Michelle Zuo, Sinah Engel, Nicholas Hanuscheck, Alexandra Florescu, Eryn Bugbee, Xianjie Iris Ma, Fatima Rana, Dennis Lee, Lesley A Ward, Jens Kuhle, Johannes Himbert, Muriel Schraad, Erwin van Puijenbroek, Christiane Neumann, Eduard Urich, Valeria Ramaglia, Anne-Katrin Pröbstel, Frauke Zipp, Jennifer L Gommerman
B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans. Science translational medicine 16 (737) (2024)
Marlena Surowka, Christiane Neumann
A pivotal decade for bispecific antibodies? mAbs 16 (1) (2024)
Marlena Surowka, Christiane Neumann
A pivotal decade for bispecific antibodies? mAbs 16 (1) (2024)
Florian Märkl, Mohamed-Reda Benmebarek, Julius Keyl, Bruno L Cadilha, Martina Geiger, Clara Karches, Hannah Obeck, Melanie Schwerdtfeger, Stefanos Michaelides, Daria Briukhovetska, Sophia Stock, Jakob Jobst, Philipp Jie Müller, Lina Majed, Matthias Seifert, Anna-Kristina Klüver, Theo Lorenzini, Ruth Grünmeier, Moritz Thomas, Adrian Gottschlich, Richard Klaus, Carsten Marr, Michael von Bergwelt-Baildon, Simon Rothenfusser, Mitchell P Levesque, Markus Vincent Heppt, Stefan Endres, Christiane Neumann, Sebastian Kobold
Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma. Journal for immunotherapy of cancer 11 (5) (2023)
Laura Codarri Deak, Masao Hashimoto, Pablo Umaña, Christiane Neumann
Beyond checkpoint inhibition: PD-1 cis-targeting of an IL-2Rβγ-biased interleukin-2 variant as a novel approach to build on checkpoint inhibition. Oncoimmunology 12 (1) (2023)
Florian Märkl, Mohamed-Reda Benmebarek, Julius Keyl, Bruno L Cadilha, Martina Geiger, Clara Karches, Hannah Obeck, Melanie Schwerdtfeger, Stefanos Michaelides, Daria Briukhovetska, Sophia Stock, Jakob Jobst, Philipp Jie Müller, Lina Majed, Matthias Seifert, Anna-Kristina Klüver, Theo Lorenzini, Ruth Grünmeier, Moritz Thomas, Adrian Gottschlich, Richard Klaus, Carsten Marr, Michael von Bergwelt-Baildon, Simon Rothenfusser, Mitchell P Levesque, Markus Vincent Heppt, Stefan Endres, Christiane Neumann, Sebastian Kobold
Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma. Journal for immunotherapy of cancer 11 (5) (2023)
Susanne C M Reinhardt, Luciano A Masullo, Isabelle Baudrexel, Philipp R Steen, Rafal Kowalewski, Alexandra S Eklund, Sebastian Strauss, Eduard M Unterauer, Thomas Schlichthaerle, Maximillian T Strauss, Christiane Neumann, Ralf Jungmann
Ångström-resolution fluorescence microscopy. Nature 617 (7962) (2023)
Gabrielle Leclercq-Cohen, Nathalie Steinhoff, Llucia Alberti Servera, Sina Nassiri, Sabrina Danilin, Emily Piccione, Emilio Yángüez, Tamara Hüsser, Sylvia Herter, Stephan Schmeing, Petra Gerber, Petra C Schwalie, Johannes Sam, Stefanie Briner, Silvia Jenni, Roberta Bianchi, Marlene Biehl, Floriana Cremasco, Katerina Apostolopoulou, Hélène Haegel, Christiane Neumann, Pablo Umaña, Marina Bacac
Dissecting the mechanisms underlying the Cytokine Release Syndrome (CRS) mediated by T Cell Bispecific Antibodies. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Raffaella Iurlaro, Inja Waldhauer, Ester Planas-Rigol, Ester Bonfill-Teixidor, Alexandra Arias, Valeria Nicolini, Anne Freimoser-Grundschober, Isabel Cuartas, Alba Martínez-Moreno, Francisco Martínez-Ricarte, Esteban Cordero, Marta Cicuéndez, Simona Casalino, Xavier Guardia-Reyes, Linda Fahrni, Thomas Pöschinger, Virginie Steinhart, Marine Richard, Stefanie Briner, Joerg Mueller, Franz Osl, Johannes Sam, Sara Colombetti, Marina Bacac, Christiane Neumann, Estela Pineda Losada, Luis Reyes-Figueroa, Alberto Di Somma, Josep González, Paolo G Nuciforo, Joan Carles, Maria Vieito, Josep Tabernero, Pablo Umaña, Joan Seoane
A Novel EGFRvIII T-Cell Bispecific Antibody for the Treatment of Glioblastoma. Molecular cancer therapeutics 21 (10) (2022)
Andrew Davies, Arnon P Kater, Jeff P Sharman, Stephan Stilgenbauer, Umberto Vitolo, Christiane Neumann, Joana Parreira, Gilles Andre Salles
Obinutuzumab in the treatment of B-cell malignancies: a comprehensive review. Future oncology (London, England) 18 (26) (2022)
Masao Hashimoto, Koichi Araki, Maria Andrea Cardenas, Peng Li, Rohit R Jadhav, Haydn T Kissick, William H Hudson, Donald J McGuire, Rebecca C Obeng, Andreas Wieland, Judong Lee, Daniel T McManus, James L Ross, Se Jin Im, Junghwa Lee, Jian-Xin Lin, Bin Hu, Erin E West, Christopher D Scharer, Gordon J Freeman, Arlene H Sharpe, Suresh R Ramalingam, Alex Pellerin, Volker Teichgräber, William J Greenleaf, Christiane Neumann, Jorg J Goronzy, Pablo Umaña, Warren J Leonard, Kendall A Smith, Rajesh M Valanparambil
PD-1 combination therapy with IL-2 modifies CD8 + T cell exhaustion program. Nature 610 (7930) (2022)
Gabrielle Leclercq-Cohen, Nathalie Steinhoff, Hélène Haegel, Donata De Marco, Marina Bacac, Christiane Neumann
Novel strategies for the mitigation of cytokine release syndrome induced by T cell engaging therapies with a focus on the use of kinase inhibitors. Oncoimmunology 11 (1) (2022)
Morgane Denis, Chloé Grasselly, Pierre-Antoine Choffour, Anne Wierinckx, Doriane Mathé, Kamel Chettab, Anne Tourette, Nolan Talhi, Aurore Bourguignon, Fabian Birzele, Elsa Kress, Lars Petter Jordheim, Christiane Neumann, Eva-Laure Matera, Charles Dumontet
In Vivo Syngeneic Tumor Models with Acquired Resistance to Anti-PD-1/PD-L1 Therapies. Cancer immunology research 10 (8) (2022)
Gabrielle Leclercq-Cohen, Hélène Haegel, Alberto Toso, Tina Zimmermann, Luke Green, Nathalie Steinhoff, Johannes Sam, Vesna Pulko, Anneliese Schneider, Anna Maria Giusti, John Challier, Anne Freimoser-Grundschober, Laurent Larivière, Alex Odermatt, Martin Stern, Pablo Umana, Marina Bacac, Christiane Neumann
JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy. Journal for immunotherapy of cancer 10 (1) (2022)
Marina Natoli, Klas Hatje, Pratiksha Gulati, Fabian Junker, Petra Herzig, Zhiwen Jiang, Iakov I Davydov, Markus Germann, Marta Trüb, Daniel Marbach, Adrian Zwick, Patrick Weber, Stefan Seeber, Mark Wiese, Didier Lardinois, Viola Heinzelmann-Schwarz, Robert Rosenberg, Lothar Tietze, Kirsten D Mertz, Pablo Umaña, Christiane Neumann, Laura Codarri-Deak, Henry Kao, Alfred Zippelius
Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors. Journal for immunotherapy of cancer 10 (11) (2022)
Sophia Stock, Mohamed-Reda Benmebarek, Anna-Kristina Kluever, Diana Darowski, Christian Jost, Kay-Gunnar Stubenrauch, Joerg Benz, Anne Freimoser-Grundschober, Ekkehard Moessner, Pablo Umana, Marion Subklewe, Stefan Endres, Christiane Neumann, Sebastian Kobold
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors. Journal for immunotherapy of cancer 10 (7) (2022)
Gabrielle Leclercq-Cohen, Llucia Alberti Servera, Sabrina Danilin, John Challier, Nathalie Steinhoff, Claudia Bossen, Alex Odermatt, Valeria Nicolini, Pablo Umaña, Christiane Neumann, Marina Bacac, Anna-Maria Giusti, Anneliese Schneider, Hélène Haegel
Dissecting the mechanism of cytokine release induced by T-cell engagers highlights the contribution of neutrophils. Oncoimmunology 11 (1) (2022)
Laura Codarri Deak, Valeria Nicolini, Masao Hashimoto, Maria Karagianni, Petra C Schwalie, Laura Lauener, Eleni Maria Varypataki, Marine Richard, Esther Bommer, Johannes Sam, Stefanie Joller, Mario Perro, Floriana Cremasco, Leo Kunz, Emilio Yanguez, Tamara Hüsser, Ramona Schlenker, Marisa Mariani, Vinko Tosevski, Sylvia Herter, Marina Bacac, Inja Waldhauer, Sara Colombetti, Xavier Gueripel, Stephan Wullschleger, Melanie Tichet, Douglas Hanahan, Haydn T Kissick, Stephane Leclair, Anne Freimoser-Grundschober, Stefan Seeber, Volker Teichgräber, Rajesh M Valanparambil, Christiane Neumann, Pablo Umaña
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8 + T cells. Nature 610 (7930) (2022)
Cornelia Fischer, Michael W Munks, Ann B Hill, Richard A Kroczek, Stefan Bissinger, Verena Brand, Martina Schmittnaegel, Sabine Imhof-Jung, Eike Hoffmann, Frank Herting, Christiane Neumann, Hendrik Knoetgen
Vaccine-induced CD8 T cells are redirected with peptide-MHC class I-IgG antibody fusion proteins to eliminate tumor cells in vivo. mAbs 12 (1) (2021)
Vittoria Massafra, Sofia Tundo, Aline Dietzig, Axel Ducret, Christian Jost, Christiane Neumann, Roland E Kontermann, Hendrik Knoetgen, Martin Steegmaier, Andrea Romagnani, Yvonne A Nagel
Proteolysis-Targeting Chimeras Enhance T Cell Bispecific Antibody-Driven T Cell Activation and Effector Function through Increased MHC Class I Antigen Presentation in Cancer Cells. Journal of immunology (Baltimore, Md. : 1950) 207 (2) (2021)
Florian Kast, Christiane Neumann, Pablo Umaña, Alena Gros, Stephan Gasser
Advances in identification and selection of personalized neoantigen/T-cell pairs for autologous adoptive T cell therapies. Oncoimmunology 10 (1) (2021)
Inja Waldhauer, Valeria Gonzalez-Nicolini, Anne Freimoser-Grundschober, Tapan K Nayak, Linda Fahrni, Ralf J Hosse, Danny Gerrits, Edwin J W Geven, Johannes Sam, Sabine Lang, Esther Bommer, Virginie Steinhart, Elisabeth Husar, Sara Colombetti, Erwin Van Puijenbroek, Markus Neubauer, J Mark Cline, Pradeep K Garg, Gregory Dugan, Federica Cavallo, Gonzalo Acuna, Jehad Charo, Volker Teichgräber, Stefan Evers, Otto C Boerman, Marina Bacac, Ekkehard Moessner, Pablo Umaña, Christiane Neumann
Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy. mAbs 13 (1) (2021)
Maud Mayoux, Andreas Roller, Vesna Pulko, Stefano Sammicheli, Stanford Chen, Eva Sum, Christian Jost, Marieke F Fransen, Regula B Buser, Marcin Kowanetz, Karolin Rommel, Ines Matos, Sara Colombetti, Anton Belousov, Vaios Karanikas, Ferry Ossendorp, Priti S Hegde, Daniel C Chen, Pablo Umaña, Mario Perro, Christiane Neumann, Wei Xu
Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy. Science translational medicine 12 (534) (2021)
Mohamed-Reda Benmebarek, Bruno L Cadilha, Monika Herrmann, Stefanie Lesch, Saskia Schmitt, Stefan Stoiber, Abbass Darwich, Christian Augsberger, Bettina Brauchle, Lisa Rohrbacher, Arman Oner, Matthias Seifert, Melanie Schwerdtfeger, Adrian Gottschlich, Felicitas Rataj, Nadja C Fenn, Christiane Neumann, Marion Subklewe, Stefan Endres, Karl-Peter Hopfner, Sebastian Kobold
A modular and controllable T cell therapy platform for acute myeloid leukemia. Leukemia 35 (8) (2021)
Enrique J Arenas Lahuerta, Alex Martínez-Sabadell, Irene Rius Ruiz, Macarena Román Alonso, Marta Escorihuela, Antonio Luque, Carlos Alberto Fajardo, Alena Gros, Christiane Neumann, Joaquín Arribas
Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation. Nature communications 12 (1) (2021)
Raquel Delgado, Karoline Kielbassa, Johanna Ter Burg, Christiane Neumann, Christine Trumpfheller, Koen de Heer, Arnon P Kater, Eric Eldering
Co-Stimulatory versus Cell Death Aspects of Agonistic CD40 Monoclonal Antibody Selicrelumab in Chronic Lymphocytic Leukemia. Cancers 13 (12) (2021)
Daphne N Dorst, Arjan P M van Caam, Elly L Vitters, Birgitte Walgreen, Monique M A Helsen, Christiane Neumann, Shreya Gudi, Tirza Wubs, Jyoti Kumari, Madelon C Vonk, Peter M van der Kraan, Marije I Koenders
Fibroblast Activation Protein Targeted Photodynamic Therapy Selectively Kills Activated Skin Fibroblasts from Systemic Sclerosis Patients and Prevents Tissue Contraction. International journal of molecular sciences 22 (23) (2021)
Miro Julian Eigenmann, Tine Veronica Karlsen, Marek Wagner, Olav Tenstad, Tina Weinzierl, Tanja Fauti, Hans Peter Grimm, Trude Skogstrand, Christiane Neumann, Johannes Sam, Pablo Umana, Marina Bacac, Helge Wiig, Antje-Christine Walz
Pharmacokinetics and Pharmacodynamics of T-Cell Bispecifics in the Tumour Interstitial Fluid. Pharmaceutics 13 (12) (2021)
Marlena Surowka, Wolfgang Schaefer, Christiane Neumann
Ten years in the making: application of CrossMab technology for the development of therapeutic bispecific antibodies and antibody fusion proteins. mAbs 13 (1) (2021)
Christian Jost, Diana Darowski, John Challier, Vesna Pulko, Lydia J Hanisch, Wei Xu, Ekkehard Mössner, Alexander Bujotzek, Stefan Klostermann, Pablo Umana, Roland E Kontermann, Christiane Neumann
CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins. mAbs 12 (1) (2021)
Christina Claus, Claudia Ferrara, Wei Xu, Johannes Sam, Sabine Lang, Franziska Uhlenbrock, Rosmarie Albrecht, Sylvia Herter, Ramona Schlenker, Tamara Hüsser, Sarah Diggelmann, John Challier, Ekkehard Mössner, Ralf J Hosse, Thomas Hofer, Peter Brünker, Catherine Joseph, Jörg Benz, Philippe Ringler, Henning Stahlberg, Matthias Lauer, Mario Perro, Stanford Chen, Christine Küttel, Preethi L Bhavani Mohan, Valeria Nicolini, Martina Carola Birk, Amandine Ongaro, Christophe Prince, Reto Gianotti, Gregory Dugan, Christopher T Whitlow, Kiran Kumar Solingapuram Sai, David L Caudell, Armando G Burgos-Rodriguez, J Mark Cline, Michael Hettich, Maurizio Ceppi, Anna Maria Giusti, Flavio Crameri, Wouter Driessen, Peter N Morcos, Anne Freimoser-Grundschober, Victor Levitsky, Maria Amann, Sandra Grau-Richards, Thomas von Hirschheydt, Stella Tournaviti, Michael Mølhøj, Tanja Fauti, Viola Heinzelmann-Schwarz, Volker Teichgräber, Sara Colombetti, Marina Bacac, Alfred Zippelius, Christiane Neumann, Pablo Umaña
Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy. Science translational medicine 11 (496) (2020)
Ivana Spasevska, Eva Laure Matera, Kamel Chettab, Jade Ville, Marie Potier-Cartereau, Lars Petter Jordheim, Catherine Thieblemont, Denis Sahin, Christiane Neumann, Charles Dumontet
Calcium Channel Blockers Impair the Antitumor Activity of Anti-CD20 Monoclonal Antibodies by Blocking EGR-1 Induction. Molecular cancer therapeutics 19 (11) (2020)
Mercedes Herrera, Artur Mezheyeuski, Lisa Villabona, Sara Corvigno, Carina Strell, Christiane Neumann, Gabriele Hölzlwimmer, Bengt Glimelius, Giuseppe V Masucci, Tobias Sjöblom, Arne Östman
Prognostic Interactions between FAP+ Fibroblasts and CD8a+ T Cells in Colon Cancer. Cancers 12 (11) (2020)
Christiane Neumann, Candice Jamois, Tina Nielsen
Anti-CD20 treatment for B-cell malignancies: current status and future directions. Expert opinion on biological therapy 21 (2) (2020)
Christoph M Griessinger, Tove Olafsen, Alessandro Mascioni, Ziyue Karen Jiang, Charles Zamilpa, Fang Jia, Michael Torgov, Jason M Romero, Filippo Marchioni, Daulet Satpayev, Chenyu Lee, Green Zhang, Tapan K Nayak, Mudita Pincha, Maria Amann, Preethi L B Mohan, Marine Richard, Valeria G Nicolini, Johannes Sam, Christina Claus, Claudia Ferrara, Peter Brünker, Marina Bacac, Pablo Umana, Dominik Rüttinger, Ian A Wilson, Jean Gudas, Christiane Neumann, Jean J L Tessier
The PET-Tracer 89Zr-Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment. Cancer research 80 (13) (2020)
Martina Geiger, Kay-Gunnar Stubenrauch, Johannes Sam, Wolfgang F Richter, Gregor Jordan, Jan Eckmann, Carina Hage, Valeria Nicolini, Anne Freimoser-Grundschober, Mirko Ritter, Matthias E Lauer, Henning Stahlberg, Philippe Ringler, Jigar Patel, Eric Sullivan, Sandra Grau-Richards, Stefan Endres, Sebastian Kobold, Pablo Umaña, Peter Brünker, Christiane Neumann
Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody. Nature communications 11 (1) (2020)
Priyanka Banerjee, Ronghua Zhang, Cristina Ivan, Giovanni Galletti, Karen Clise-Dwyer, Federica Barbaglio, Lydia Scarfò, Miguel Aracil, Christiane Neumann, William Wierda, William Plunkett, Federico Caligaris-Cappio, Varsha Gandhi, Michael J Keating, Maria Teresa S Bertilaccio
Trabectedin Reveals a Strategy of Immunomodulation in Chronic Lymphocytic Leukemia. Cancer immunology research 7 (12) (2019)
Morgane Agez, Elodie Desuzinges Mandon, Thomas Iwema, Reto Gianotti, Florian Limani, Sylvia Herter, Ekkehard Mössner, Eric A Kusznir, Sylwia Huber, Matthias E Lauer, Philippe Ringler, Claudia Ferrara, Christiane Neumann, Anass Jawhari
Biochemical and biophysical characterization of purified native CD20 alone and in complex with rituximab and obinutuzumab. Scientific reports 9 (1) (2019)
Irene Rius Ruiz, Rocio Vicario, Beatriz Morancho, Cristina Bernadó Morales, Enrique J Arenas Lahuerta, Sylvia Herter, Anne Freimoser-Grundschober, Jitka Somandin, Johannes Sam, Oliver Ast, Águeda Martinez Barriocanal, Antonio Luque, Marta Escorihuela, Ismael Varela, Isabel Cuartas, Paolo G Nuciforo, Roberta Fasani, Vicente Peg, Isabel Rubio, Javier Cortes, Violeta Serra, Santiago Escriva-de-Romani, Jeff Sperinde, Ahmed Chenna, Weidong Huang, John Winslow, Joan Albanell, Joan Seoane, Maurizio Scaltriti, Jose Baselga, Josep Tabernero, Pablo Umana, Marina Bacac, Cristina Saura, Christiane Neumann, Joaquín Arribas
p95HER2-T cell bispecific antibody for breast cancer treatment. Science translational medicine 10 (461) (2019)
Magdalena Klanova, Mikkel Z Oestergaard, Marek Trněný, Wolfgang Hiddemann, Robert Marcus, Laurie H Sehn, Umberto Vitolo, Alexandra Bazeos, Valentin Goede, Harald Zeuner, Andrea Knapp, Deniz Sahin, Nathalie Spielewoy, Christopher R Bolen, Andres Cardona, Christiane Neumann, Jeffrey M Venstrom, Tina Nielsen, Günter Fingerle-Rowson
Prognostic Impact of Natural Killer Cell Count in Follicular Lymphoma and Diffuse Large B-cell Lymphoma Patients Treated with Immunochemotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (15) (2019)
Diana Darowski, Sebastian Kobold, Christian Jost, Christiane Neumann
Combining the best of two worlds: highly flexible chimeric antigen receptor adaptor molecules (CAR-adaptors) for the recruitment of chimeric antigen receptor T cells. mAbs 11 (4) (2019)
Claudio Sustmann, Steffen Dickopf, Jörg T Regula, Hubert Kettenberger, Michael Mølhøj, Christian Gassner, Diana Weininger, Sebastian Fenn, Tobias Manigold, Lothar Kling, Klaus-Peter Künkele, Manfred Schwaiger, Birgit Bossenmaier, Julia J Griese, Karl-Peter Hopfner, Alexandra Graff-Meyer, Henning Stahlberg, Philippe Ringler, Matthias E Lauer, Ulrich Brinkmann, Wolfgang Schaefer, Christiane Neumann
DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity. mAbs 11 (8) (2019)
Daniela S Thommen, Viktor H Koelzer, Petra Herzig, Andreas Roller, Marcel Philipp Trefny, Sarah Dimeloe, Anna Kiialainen, Jonathan Hanhart, Catherine Schill, Christoph Hess, Spasenija Savic Prince, Mark Wiese, Didier Lardinois, Ping-Chih Ho, Christiane Neumann, Vaios Karanikas, Kirsten D Mertz, Ton N Schumacher, Alfred Zippelius
A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade. Nature medicine 24 (7) (2018)
Cédric Rossi, Pauline Gravelle, Emilie Decaup, Julie Bordenave, Mary Poupot, Marie Tosolini, Don-Marc Franchini, Camille Laurent, Renaud Morin, Jean-Michel Lagarde, Loïc Ysebaert, Laetitia Ligat, Christine Jean, Ariel Savina, Christiane Neumann, Alba Matas Céspedes, Patricia Perez-Galan, Jean-Jacques Fournié, Christine Bezombes
Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma. Oncoimmunology 8 (3) (2018)
Adam Palazzo, Sylvia Herter, Laura Grosmaire, Randy Jones, Christian R Frey, Florian Limani, Marina Bacac, Pablo Umana, Robert J Oldham, Michael J E Marshall, Kerry L Cox, Anna H Turaj, Mark S Cragg, Christiane Neumann, Matthew J Carter, Stacey Tannheimer
The PI3Kδ-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo. Journal of immunology (Baltimore, Md. : 1950) 200 (7) (2018)
Marina Bacac, Sara Colombetti, Sylvia Herter, Johannes Sam, Mario Perro, Stanford Chen, Roberta Bianchi, Marine Richard, Anne Freimoser-Grundschober, Valeria Nicolini, Sarah Diggelmann, Florian Limani, Ramona Schlenker, Tamara Hüsser, Wolfgang Richter, Katharine Bray-French, Heather Hinton, Anna Maria Giusti, Anne Freimoser-Grundschober, Laurent Lariviere, Christiane Neumann, Christian Klein, Pablo Umaña
CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research 24 (19) (2018)
Frank Herting, Thomas Friess, Pablo Umaña, Steven Middleton, Christiane Neumann
Chemotherapy-free, triple combination of obinutuzumab, venetoclax and idasanutlin: antitumor activity in xenograft models of non-Hodgkin lymphoma. Leukemia & lymphoma 59 (6) (2017)
Christiane Neumann, Marina Bacac, Pablo Umana, Günter Fingerle-Rowson
Combination therapy with the type II anti-CD20 antibody obinutuzumab. Expert opinion on investigational drugs 26 (10) (2017)
E J Cheadle, G Lipowska-Bhalla, S J Dovedi, E Fagnano, Christiane Neumann, J Honeychurch, T M Illidge
A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells. Leukemia 31 (7) (2017)