Ignacio Melero Bermejo (Ignacio Melero)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 86

Top Topics

Endometrial Cancer

Monoclonal Antibody

Top Venues

Journal for immunotherapy of cancer

Clinical cancer research : an official journal of the American Association for Cancer Research

Nature communications

Cancer discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Iñaki Eguren, Eva Fernández de Piérola, Gracián Camps, Paula Martín-Muñoz, María Campos, Doina Cuculescu, Inmaculada Aguilera-Buenosvinos, Inmaculada Rodríguez López, Rafael Salido-Vallejo, Raluca Alexandru, Carlos E De Andrea, Laura Álvarez-Gigli, Pedro Berraondo, Ignacio Melero Bermejo, Miguel F Sanmamed
MHC class I and II-deficient humanized mice are suitable tools to test the long-term antitumor efficacy of immune checkpoint inhibitors and T-cell engagers. Journal for immunotherapy of cancer 12 (9) (2024)
Paolo Antonio Ascierto, Milena Casula, Jenny Bulgarelli, Marina Pisano, Claudia Piccinini, Luisa Piccin, Antonio Cossu, Mario Mandala, Pier Francesco Ferrucci, Massimo Guidoboni, Piotr Lukasz Rutkowski, Virginia Ferraresi, Ana M Arance, Michele Guida, Evaristo Maiello, Helen Gogas, Erika Richtig, Maria Teresa Fierro, Celeste Lebbè, Hildur Helgadottir, Paola Queirolo, Francesco Spagnolo, Marco Tucci, Michele Del Vecchio, Maria Gonzales Cao, Alessandro Marco Minisini, Sabino De Placido, Miguel F Sanmamed, Domenico Mallardo, Miriam Paone, Maria Grazia Vitale, Ignacio Melero Bermejo, Antonio M Grimaldi, Diana Giannarelli, Reinhard Dummer, Vanna Chiarion Sileni, Giuseppe Palmieri
Sequential immunotherapy and targeted therapy for metastatic BRAF V600 mutated melanoma: 4-year survival and biomarkers evaluation from the phase II SECOMBIT trial. Nature communications 15 (1) (2024)
Álvaro López-Janeiro, Eduardo Miraval Wong, Daniel Jiménez-Sánchez, Carlos Ortiz de Solorzano, Maria D Lozano, Alvaro Teijeira, Kurt A Schalper, Ignacio Melero Bermejo, Carlos E De Andrea
Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densities. Journal for immunotherapy of cancer 12 (5) (2024)
Paolo Antonio Ascierto, Milena Casula, Jenny Bulgarelli, Marina Pisano, Claudia Piccinini, Luisa Piccin, Antonio Cossu, Mario Mandala, Pier Francesco Ferrucci, Massimo Guidoboni, Piotr Lukasz Rutkowski, Virginia Ferraresi, Ana M Arance, Michele Guida, Evaristo Maiello, Helen Gogas, Erika Richtig, Maria Teresa Fierro, Celeste Lebbè, Hildur Helgadottir, Paola Queirolo, Francesco Spagnolo, Marco Tucci, Michele Del Vecchio, Maria Gonzales Cao, Alessandro Marco Minisini, Sabino De Placido, Miguel F Sanmamed, Domenico Mallardo, Miriam Paone, Maria Grazia Vitale, Ignacio Melero Bermejo, Antonio M Grimaldi, Diana Giannarelli, Reinhard Dummer, Vanna Chiarion Sileni, Giuseppe Palmieri
Sequential immunotherapy and targeted therapy for metastatic BRAF V600 mutated melanoma: 4-year survival and biomarkers evaluation from the phase II SECOMBIT trial. Nature communications 15 (1) (2024)
Solange Peters, Eric Angevin, Teresa Alonso Gordoa, Kristoffer Staal Rohrberg, Ignacio Melero Bermejo, Begona Mellado, Jose-Luis Perez-Gracia, Josep Tabernero, Celine Adessi, Christophe Boetsch, Carl Watson, Joseph Dal Porto, David Dejardin, Christopher Del Nagro, Valeria Nicolini, Stefan Evers, Christiane Neumann, Barbara Leutgeb, Pavel Pisa, Eva Rossmann, José Saro, Pablo Umaña, Jehad Charo, Volker Teichgräber, Neeltje Steeghs
Obinutuzumab Pretreatment as a Novel Approach to Mitigate Formation of Anti-Drug Antibodies Against Cergutuzumab Amunaleukin in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Celia Gomar, Claudia Augusta Di Trani, Angela Bella, Leire Arrizabalaga, Jose Gonzalez-Gomariz, Myriam Fernandez-Sendin, Maite Alvarez, Joan Salvador Russo-Cabrera, Nuria Ardaiz, Fernando Aranda, Timo Schippers, Marisol Quintero, Ignacio Melero Bermejo, Klaus K Orlinger, Henning Lauterbach, Pedro Berraondo
Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C. Journal for immunotherapy of cancer 12 (4) (2024)
Celia Gomar, Claudia Augusta Di Trani, Angela Bella, Leire Arrizabalaga, Jose Gonzalez-Gomariz, Myriam Fernandez-Sendin, Maite Alvarez, Joan Salvador Russo-Cabrera, Nuria Ardaiz, Fernando Aranda, Timo Schippers, Marisol Quintero, Ignacio Melero Bermejo, Klaus K Orlinger, Henning Lauterbach, Pedro Berraondo
Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C. Journal for immunotherapy of cancer 12 (4) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Solange Peters, Eric Angevin, Teresa Alonso Gordoa, Kristoffer Staal Rohrberg, Ignacio Melero Bermejo, Begona Mellado, Jose-Luis Perez-Gracia, Josep Tabernero, Celine Adessi, Christophe Boetsch, Carl Watson, Joseph Dal Porto, David Dejardin, Christopher Del Nagro, Valeria Nicolini, Stefan Evers, Christiane Neumann, Barbara Leutgeb, Pavel Pisa, Eva Rossmann, José Saro, Pablo Umaña, Jehad Charo, Volker Teichgräber, Neeltje Steeghs
Obinutuzumab Pretreatment as a Novel Approach to Mitigate Formation of Anti-Drug Antibodies Against Cergutuzumab Amunaleukin in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Celia Gomar, Claudia Augusta Di Trani, Angela Bella, Leire Arrizabalaga, Jose Gonzalez-Gomariz, Myriam Fernandez-Sendin, Maite Alvarez, Joan Salvador Russo-Cabrera, Nuria Ardaiz, Fernando Aranda, Timo Schippers, Marisol Quintero, Ignacio Melero Bermejo, Klaus K Orlinger, Henning Lauterbach, Pedro Berraondo
Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C. Journal for immunotherapy of cancer 12 (4) (2024)
Ana Martinez-Riaño, Laura Mosteo, Paula Molero-Glez, Ivan Marquez-Rodas, Ignacio Melero Bermejo
Double-stranded RNA to mimic viral infection for cancer immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Jason John Luke, Diwakar Davar, Robert H Andtbacka, Nina Bhardwaj, Joshua D Brody, Jason A Chesney, Robert Coffin, Thierry de Baere, Tanja D de Gruijl, Matthew Fury, Gregory Goldmacher, Kevin J Harrington, Howard Kaufman, Ciara M Kelly, Anuradha D Khilnani, Ke Liu, Sherene Loi, Georgina V Long, Ignacio Melero Bermejo, Mark Ross Middleton, Bart Neyns, David James Pinato, Rahul A Sheth, Stephen B Solomon, Philippe Szapary, Aurélien Marabelle
Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. Journal for immunotherapy of cancer 12 (4) (2024)
Ana Martinez-Riaño, Laura Mosteo, Paula Molero-Glez, Ivan Marquez-Rodas, Ignacio Melero Bermejo
Double-Stranded RNA to Mimic Viral Infection for Cancer Immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (16) (2024)
Iñaki Eguren-Santamaría, Inmaculada Rodríguez, Claudia Herrero-Martin, Eva Fernández de Piérola, Arantza Azpilikueta, Sandra Sánchez-Gregorio, Elixabet Bolaños, Gabriel Gomis, Paula Molero-Glez, Enrique Chacón, José Ángel Mínguez, Santiago Chiva, Fernando Diez-Caballero, Carlos de Andrea, Álvaro Teijeira, Miguel F Sanmamed, Ignacio Melero Bermejo
Short-term cultured tumor fragments to study immunotherapy combinations based on CD137 (4-1BB) agonism. Oncoimmunology 13 (1) (2024)
Alvaro Teijeira, Saray Garasa, María Carmen Ochoa, Sandra Sanchez-Gregorio, Gabriel Gomis, Carlos Luri-Rey, Rafael Martinez-Monge, Beatrice Pinci, Karmele Valencia, Belen Palencia, Benigno Barbes, Elixabet Bolaños, Arantza Azpilikueta, Marina Garcia-Cardosa, Javier Burguete, Iñaki Eguren, Eneko Garate-Soraluze, Pedro Berraondo, Jose-Luis Perez-Gracia, Carlos E De Andrea, Maria E Rodríguez-Ruiz, Ignacio Melero Bermejo
Low-dose ionizing γ-radiation elicits the extrusion of neutrophil extracellular traps. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Iñaki Eguren-Santamaría, Inmaculada Rodríguez, Claudia Herrero-Martin, Eva Fernández de Piérola, Arantza Azpilikueta, Sandra Sánchez-Gregorio, Elixabet Bolaños, Gabriel Gomis, Paula Molero-Glez, Enrique Chacón, José Ángel Mínguez, Santiago Chiva, Fernando Diez-Caballero, Carlos de Andrea, Álvaro Teijeira, Miguel F Sanmamed, Ignacio Melero Bermejo
Short-term cultured tumor fragments to study immunotherapy combinations based on CD137 (4-1BB) agonism. Oncoimmunology 13 (1) (2024)
Neeltje Steeghs, Carlos Alberto Gomez Roca, Kristoffer Staal Rohrberg, Morten Mau Sorensen, Debbie G J Robbrecht, Josep Tabernero, Samreen Ahmed, Maria E Rodríguez-Ruiz, Caroline Ardeshir, Daniela Schmid, Nassim Sleiman, Carl Watson, Hanna Piper-Lepoutre, David Dejardin, Stefan Evers, Christophe Boetsch, Jehad Charo, Volker Teichgräber, Ignacio Melero Bermejo
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (13) (2024)
Nikhil I Khushalani, Patrick A Ott, Matthew J Ferris, Tina Cascone, Dirk Schadendorf, Dung T Le, Manish R Sharma, Fabrice Barlesi, William Sharfman, Jason John Luke, Ignacio Melero Bermejo, Deanne Lathers, Jaclyn Neely, Satyendra Suryawanshi, Abanti Sanyal, James L Holloway, Rasika Suryawanshi, Scott Ely, Neil H Segal
Final results of urelumab, an anti-CD137 agonist monoclonal antibody, in combination with cetuximab or nivolumab in patients with advanced solid tumors. Journal for immunotherapy of cancer 12 (3) (2024)
Iñaki Eguren-Santamaría, Inmaculada Rodríguez, Claudia Herrero-Martin, Eva Fernández de Piérola, Arantza Azpilikueta, Sandra Sánchez-Gregorio, Elixabet Bolaños, Gabriel Gomis, Paula Molero-Glez, Enrique Chacón, José Ángel Mínguez, Santiago Chiva, Fernando Diez-Caballero, Carlos de Andrea, Álvaro Teijeira, Miguel F Sanmamed, Ignacio Melero Bermejo
Short-term cultured tumor fragments to study immunotherapy combinations based on CD137 (4-1BB) agonism. Oncoimmunology 13 (1) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Jason John Luke, Diwakar Davar, Robert H Andtbacka, Nina Bhardwaj, Joshua D Brody, Jason A Chesney, Robert Coffin, Thierry de Baere, Tanja D de Gruijl, Matthew Fury, Gregory Goldmacher, Kevin J Harrington, Howard Kaufman, Ciara M Kelly, Anuradha D Khilnani, Ke Liu, Sherene Loi, Georgina V Long, Ignacio Melero Bermejo, Mark Ross Middleton, Bart Neyns, David James Pinato, Rahul A Sheth, Stephen B Solomon, Philippe Szapary, Aurélien Marabelle
Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. Journal for immunotherapy of cancer 12 (4) (2024)
Paula Molero-Glez, Arantza Azpilikueta, Laura Mosteo, Javier Glez-Vaz, Belen Palencia, Ignacio Melero Bermejo
CD137 (4-1BB) and T-Lymphocyte Exhaustion. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Álvaro López-Janeiro, Eduardo Miraval Wong, Daniel Jiménez-Sánchez, Carlos Ortiz de Solorzano, Maria D Lozano, Alvaro Teijeira, Kurt A Schalper, Ignacio Melero Bermejo, Carlos E De Andrea
Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densities. Journal for immunotherapy of cancer 12 (5) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Neeltje Steeghs, Carlos Alberto Gomez Roca, Kristoffer Staal Rohrberg, Morten Mau Sorensen, Debbie G J Robbrecht, Josep Tabernero, Samreen Ahmed, Maria E Rodríguez-Ruiz, Caroline Ardeshir, Daniela Schmid, Nassim Sleiman, Carl Watson, Hanna Piper-Lepoutre, David Dejardin, Stefan Evers, Christophe Boetsch, Jehad Charo, Volker Teichgräber, Ignacio Melero Bermejo
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (13) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Jason John Luke, Diwakar Davar, Robert H Andtbacka, Nina Bhardwaj, Joshua D Brody, Jason A Chesney, Robert Coffin, Thierry de Baere, Tanja D de Gruijl, Matthew Fury, Gregory Goldmacher, Kevin J Harrington, Howard Kaufman, Ciara M Kelly, Anuradha D Khilnani, Ke Liu, Sherene Loi, Georgina V Long, Ignacio Melero Bermejo, Mark Ross Middleton, Bart Neyns, David James Pinato, Rahul A Sheth, Stephen B Solomon, Philippe Szapary, Aurélien Marabelle
Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. Journal for immunotherapy of cancer 12 (4) (2024)
Celia Gomar, Claudia Augusta Di Trani, Angela Bella, Leire Arrizabalaga, Jose Gonzalez-Gomariz, Myriam Fernandez-Sendin, Maite Alvarez, Joan Salvador Russo-Cabrera, Nuria Ardaiz, Fernando Aranda, Timo Schippers, Marisol Quintero, Ignacio Melero Bermejo, Klaus K Orlinger, Henning Lauterbach, Pedro Berraondo
Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C. Journal for immunotherapy of cancer 12 (4) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Nikhil I Khushalani, Patrick A Ott, Matthew J Ferris, Tina Cascone, Dirk Schadendorf, Dung T Le, Manish R Sharma, Fabrice Barlesi, William Sharfman, Jason John Luke, Ignacio Melero Bermejo, Deanne Lathers, Jaclyn Neely, Satyendra Suryawanshi, Abanti Sanyal, James L Holloway, Rasika Suryawanshi, Scott Ely, Neil H Segal
Final results of urelumab, an anti-CD137 agonist monoclonal antibody, in combination with cetuximab or nivolumab in patients with advanced solid tumors. Journal for immunotherapy of cancer 12 (3) (2024)
Neeltje Steeghs, Carlos Alberto Gomez Roca, Kristoffer Staal Rohrberg, Morten Mau Sorensen, Debbie G J Robbrecht, Josep Tabernero, Samreen Ahmed, Maria E Rodríguez-Ruiz, Caroline Ardeshir, Daniela Schmid, Nassim Sleiman, Carl Watson, Hanna Piper-Lepoutre, David Dejardin, Stefan Evers, Christophe Boetsch, Jehad Charo, Volker Teichgräber, Ignacio Melero Bermejo
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (13) (2024)
Nikhil I Khushalani, Patrick A Ott, Matthew J Ferris, Tina Cascone, Dirk Schadendorf, Dung T Le, Manish R Sharma, Fabrice Barlesi, William Sharfman, Jason John Luke, Ignacio Melero Bermejo, Deanne Lathers, Jaclyn Neely, Satyendra Suryawanshi, Abanti Sanyal, James L Holloway, Rasika Suryawanshi, Scott Ely, Neil H Segal
Final results of urelumab, an anti-CD137 agonist monoclonal antibody, in combination with cetuximab or nivolumab in patients with advanced solid tumors. Journal for immunotherapy of cancer 12 (3) (2024)
Nikhil I Khushalani, Patrick A Ott, Matthew J Ferris, Tina Cascone, Dirk Schadendorf, Dung T Le, Manish R Sharma, Fabrice Barlesi, William Sharfman, Jason John Luke, Ignacio Melero Bermejo, Deanne Lathers, Jaclyn Neely, Satyendra Suryawanshi, Abanti Sanyal, James L Holloway, Rasika Suryawanshi, Scott Ely, Neil H Segal
Final results of urelumab, an anti-CD137 agonist monoclonal antibody, in combination with cetuximab or nivolumab in patients with advanced solid tumors. Journal for immunotherapy of cancer 12 (3) (2024)
Celia Gomar, Claudia Augusta Di Trani, Angela Bella, Leire Arrizabalaga, Jose Gonzalez-Gomariz, Myriam Fernandez-Sendin, Maite Alvarez, Joan Salvador Russo-Cabrera, Nuria Ardaiz, Fernando Aranda, Timo Schippers, Marisol Quintero, Ignacio Melero Bermejo, Klaus K Orlinger, Henning Lauterbach, Pedro Berraondo
Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C. Journal for immunotherapy of cancer 12 (4) (2024)
Jason John Luke, Diwakar Davar, Robert H Andtbacka, Nina Bhardwaj, Joshua D Brody, Jason A Chesney, Robert Coffin, Thierry de Baere, Tanja D de Gruijl, Matthew Fury, Gregory Goldmacher, Kevin J Harrington, Howard Kaufman, Ciara M Kelly, Anuradha D Khilnani, Ke Liu, Sherene Loi, Georgina V Long, Ignacio Melero Bermejo, Mark Ross Middleton, Bart Neyns, David James Pinato, Rahul A Sheth, Stephen B Solomon, Philippe Szapary, Aurélien Marabelle
Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. Journal for immunotherapy of cancer 12 (4) (2024)
Nikhil I Khushalani, Patrick A Ott, Matthew J Ferris, Tina Cascone, Dirk Schadendorf, Dung T Le, Manish R Sharma, Fabrice Barlesi, William Sharfman, Jason John Luke, Ignacio Melero Bermejo, Deanne Lathers, Jaclyn Neely, Satyendra Suryawanshi, Abanti Sanyal, James L Holloway, Rasika Suryawanshi, Scott Ely, Neil H Segal
Final results of urelumab, an anti-CD137 agonist monoclonal antibody, in combination with cetuximab or nivolumab in patients with advanced solid tumors. Journal for immunotherapy of cancer 12 (3) (2024)
Álvaro López-Janeiro, Eduardo Miraval Wong, Daniel Jiménez-Sánchez, Carlos Ortiz de Solorzano, Maria D Lozano, Alvaro Teijeira, Kurt A Schalper, Ignacio Melero Bermejo, Carlos E De Andrea
Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densities. Journal for immunotherapy of cancer 12 (5) (2024)
Neeltje Steeghs, Carlos Alberto Gomez Roca, Kristoffer Staal Rohrberg, Morten Mau Sorensen, Debbie G J Robbrecht, Josep Tabernero, Samreen Ahmed, Maria E Rodríguez-Ruiz, Caroline Ardeshir, Daniela Schmid, Nassim Sleiman, Carl Watson, Hanna Piper-Lepoutre, David Dejardin, Stefan Evers, Christophe Boetsch, Jehad Charo, Volker Teichgräber, Ignacio Melero Bermejo
Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity from a Phase I Study of Simlukafusp Alfa (FAP-IL2v) in Advanced/Metastatic Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Praveen Weeratunga, Laura Denney, Joshua A Bull, Emmanouela Repapi, Martin J Sergeant, Rachel Etherington, Chaitanya Vuppussetty, Gareth D H Turner, Colin Clelland, Jeongmin Woo, Amy Cross, Fadi Issa, Carlos Eduardo de Andrea, Ignacio Melero Bermejo, David Sims, Simon J McGowan, Yasemin-Xiomara Zurke, David J Ahern, Eddie C Gamez, Justin P Whalley, Duncan B Richards, Paul Klenerman, Claudia Monaco, Irina A Udalova, Tao Dong, Agne Antanaviciute, Graham S Ogg, Julian C Knight, Helen M Byrne, Stephen Taylor, Ling-Pei Ho
Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs. Nature communications 14 (1) (2023)
Javier Glez-Vaz, Arantza Azpilikueta, María Carmen Ochoa, Irene Olivera, Gabriel Gomis, Assunta Cirella, Carlos Luri-Rey, Maite Alvarez, Jose-Luis Perez-Gracia, Sergio Ciordia, Iñaki Eguren, Raluca Alexandru, Pedro Berraondo, Carlos E De Andrea, Alvaro Teijeira, Fernando Corrales, Juan M Zapata, Ignacio Melero Bermejo
CD137 (4-1BB) requires physically associated cIAPs for signal transduction and antitumor effects. Science advances 9 (33) (2023)
Irene Olivera, Carlos Luri-Rey, Alvaro Teijeira, Iñaki Eguren, Gabriel Gomis, Belen Palencia, Pedro Berraondo, Ignacio Melero Bermejo
Facts and hopes on neutralization of protumor inflammatory mediators in cancer immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Maria E Rodríguez-Ruiz, Irantzu Serrano-Mendioroz, Eneko Garate-Soraluze, Paloma Sánchez-Mateos, Celia Barrio-Alonso, Inmaculada Rodríguez López, Victor Diaz Pascual, Leire Arbea Moreno, Maite Alvarez, Miguel F Sanmamed, Jose Luis Perez-Gracia, Helena Escuin-Ordinas, Marisol Quintero, Ignacio Melero Bermejo
Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control. Journal for immunotherapy of cancer 11 (1) (2023)
Jara Palomero, Carla Panisello, Maria Lozano-Rabella, Ricky Tirtakasuma, Judit Díaz-Gómez, Daniela Grases, Helena Pasamar, Laura Arregui, Eduard Dorca Duch, Esther Guerra Fernández, Ana Vivancos, Carlos E de Andrea, Ignacio Melero Bermejo, Jordi Ponce, August Vidal, Josep Maria Piulats, Xavier Matias-Guiu, Alena Gros
Biomarkers of tumor-reactive CD4 + and CD8 + TILs associate with improved prognosis in endometrial cancer. Journal for immunotherapy of cancer 10 (12) (2023)
Carlos Luri-Rey, Gabriel Gomis, Javier Glez-Vaz, Almudena Manzanal, Ana Martinez Riaño, Maria E Rodriguez Ruiz, Alvaro Teijeira, Ignacio Melero Bermejo
Cytotoxicity as a form of immunogenic cell death leading to efficient tumor antigen cross-priming. Immunological reviews (2023)
Carlos Luri-Rey, Iñaki Eguren, Ignacio Matos, Pedro Berraondo, Ignacio Melero Bermejo
Druggable targets in cytokine release syndromes. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Ignacio Melero Bermejo, Tamara Tanos, Mariana Bustamante, Miguel F Sanmamed, Emiliano Calvo, Irene Moreno-Candilejo, Victor Moreno, Tatiana Hernández, Maria Martinez-García, Alejo Rodriguez-Vida, Josep Tabernero, Analia Azaro, Mariano Ponz-Sarvisé, Iben Spanggaard, Kristoffer Staal Rohrberg, Ernesto Guarin, Eveline Nüesch, Iakov I Davydov, Chia-Huey Ooi, José Duarte, Evelyne Chesne, Christine McIntyre, Maurizio Ceppi, Marta Cañamero, Oliver Krieter
A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors. Science translational medicine 15 (695) (2023)
Jara Palomero, Carla Panisello, Maria Lozano-Rabella, Ricky Tirtakasuma, Judit Díaz-Gómez, Daniela Grases, Helena Pasamar, Laura Arregui, Eduard Dorca Duch, Esther Guerra Fernández, Ana Vivancos, Carlos E de Andrea, Ignacio Melero Bermejo, Jordi Ponce, August Vidal, Josep Maria Piulats, Xavier Matias-Guiu, Alena Gros
Biomarkers of tumor-reactive CD4 + and CD8 + TILs associate with improved prognosis in endometrial cancer. Journal for immunotherapy of cancer 10 (12) (2023)
Jara Palomero, Carla Panisello, Maria Lozano-Rabella, Ricky Tirtakasuma, Judit Díaz-Gómez, Daniela Grases, Helena Pasamar, Laura Arregui, Eduard Dorca Duch, Esther Guerra Fernández, Ana Vivancos, Carlos E de Andrea, Ignacio Melero Bermejo, Jordi Ponce, August Vidal, Josep Maria Piulats, Xavier Matias-Guiu, Alena Gros
Biomarkers of tumor-reactive CD4 + and CD8 + TILs associate with improved prognosis in endometrial cancer. Journal for immunotherapy of cancer 10 (12) (2023)
Ignacio Melero Bermejo, Miguel F Sanmamed, Javier Glez-Vaz, Carlos Luri-Rey, Jun Wang, Lieping Chen
CD137 (4-1BB)-Based Cancer Immunotherapy on Its 25th Anniversary. Cancer discovery 13 (3) (2023)
Maria E Rodríguez-Ruiz, Irantzu Serrano-Mendioroz, Eneko Garate-Soraluze, Paloma Sánchez-Mateos, Celia Barrio-Alonso, Inmaculada Rodríguez López, Victor Diaz Pascual, Leire Arbea Moreno, Maite Alvarez, Miguel F Sanmamed, Jose Luis Perez-Gracia, Helena Escuin-Ordinas, Marisol Quintero, Ignacio Melero Bermejo
Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control. Journal for immunotherapy of cancer 11 (1) (2023)
Ignacio Melero Bermejo, Tamara Tanos, Mariana Bustamante, Miguel F Sanmamed, Emiliano Calvo, Irene Moreno-Candilejo, Victor Moreno, Tatiana Hernández, Maria Martinez-García, Alejo Rodriguez-Vida, Josep Tabernero, Analia Azaro, Mariano Ponz-Sarvisé, Iben Spanggaard, Kristoffer Staal Rohrberg, Ernesto Guarin, Eveline Nüesch, Iakov I Davydov, Chia-Huey Ooi, José Duarte, Evelyne Chesne, Christine McIntyre, Maurizio Ceppi, Marta Cañamero, Oliver Krieter
A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors. Science translational medicine 15 (695) (2023)
Ignacio Melero Bermejo, Maria C Ochoa, Carmen Molina, Sandra Sanchez-Gregorio, Saray Garasa, Carlos Luri-Rey, Sandra Hervas-Stubbs, Noelia Casares, Edurne Elizalde, Gabriel Gomis, Assunta Cirella, Pedro Berraondo, Alvaro Teijeira, Maite Alvarez
Intratumoral co-injection of NK cells and NKG2A-neutralizing monoclonal antibodies. EMBO molecular medicine (2023)
Maite Alvarez, Carmen Molina, Saray Garasa, Maria C Ochoa, Maria E Rodriguez-Ruiz, Gabriel Gomis, Assunta Cirella, Irene Olivera, Javier Glez-Vaz, Jose Gonzalez-Gomariz, Carlos Luri-Rey, Arantza Azpilikueta, Elixabet Bolaños, Alvaro Teijeira, Pedro Berraondo, Marisol Quintero, Ignacio Melero Bermejo
Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic. Oncoimmunology 12 (1) (2023)
Maria E Rodríguez-Ruiz, Irantzu Serrano-Mendioroz, Eneko Garate-Soraluze, Paloma Sánchez-Mateos, Celia Barrio-Alonso, Inmaculada Rodríguez López, Victor Diaz Pascual, Leire Arbea Moreno, Maite Alvarez, Miguel F Sanmamed, Jose Luis Perez-Gracia, Helena Escuin-Ordinas, Marisol Quintero, Ignacio Melero Bermejo
Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control. Journal for immunotherapy of cancer 11 (1) (2023)
Maria E Rodríguez-Ruiz, Irantzu Serrano-Mendioroz, Eneko Garate-Soraluze, Paloma Sánchez-Mateos, Celia Barrio-Alonso, Inmaculada Rodríguez López, Victor Diaz Pascual, Leire Arbea Moreno, Maite Alvarez, Miguel F Sanmamed, Jose Luis Perez-Gracia, Helena Escuin-Ordinas, Marisol Quintero, Ignacio Melero Bermejo
Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control. Journal for immunotherapy of cancer 11 (1) (2023)
Ángela Bella, Leire Arrizabalaga, Claudia Augusta Di Trani, Jose Gonzalez-Gomariz, Celia Gomar, Joan Salvador Russo-Cabrera, Irene Olivera, Assunta Cirella, Myriam Fernandez-Sendin, Maite Alvarez, Alvaro Teijeira, Cigdem Atay, José Medina-Echeverz, Maria Hinterberger, Hubertus Hochrein, Ignacio Melero Bermejo, Pedro Berraondo, Fernando Aranda
Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis. Journal for immunotherapy of cancer 11 (11) (2023)
Jara Palomero, Carla Panisello, Maria Lozano-Rabella, Ricky Tirtakasuma, Judit Díaz-Gómez, Daniela Grases, Helena Pasamar, Laura Arregui, Eduard Dorca Duch, Esther Guerra Fernández, Ana Vivancos, Carlos E de Andrea, Ignacio Melero Bermejo, Jordi Ponce, August Vidal, Josep Maria Piulats, Xavier Matias-Guiu, Alena Gros
Biomarkers of tumor-reactive CD4 + and CD8 + TILs associate with improved prognosis in endometrial cancer. Journal for immunotherapy of cancer 10 (12) (2023)
Karmele Valencia, Mirari Echepare, Andrea Pasquier, Cristina Bértolo, Cristina Sainz, Ibon Tamayo-Uria, Beñat Picabea, Graziella Bosco, Roman K Thomas, Jackeline Agorreta, José María López-Picazo, Joan Frigola, Ramon Amat, Alfonso Calvo, Enriqueta Felip Font, Ignacio Melero Bermejo, Luis M Montuenga
DSTYK inhibition increases the sensitivity of lung cancer cells to T cell-mediated cytotoxicity. The Journal of experimental medicine 219 (12) (2022)
Ignacio Melero Bermejo, Miguel F Sanmamed, Javier Glez-Vaz, Carlos Luri-Rey, Jun Wang, Lieping Chen
CD137 (4-1BB)-Based Cancer Immunotherapy on Its 25th Anniversary. Cancer discovery (2022)
Javier Glez-Vaz, Arantza Azpilikueta, Irene Olivera, Assunta Cirella, Alvaro Teijeira, Maria C Ochoa, Maite Alvarez, Iñaki Eguren, Carlos Luri-Rey, Maria E Rodriguez-Ruiz, Xinxin Nie, Lieping Chen, Sonia Guedan, Miguel F Sanamed, Jose Luis Perez Gracia, Ignacio Melero Bermejo
Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies. Journal for immunotherapy of cancer 10 (3) (2022)
Miguel F Sanmamed, Pedro Berraondo, Maria E Rodriguez-Ruiz, Ignacio Melero Bermejo
Charting roadmaps towards novel and safe synergistic immunotherapy combinations. Nature cancer 3 (6) (2022)
Borja Ruiz-Fernández de Córdoba, Haritz Moreno, Karmele Valencia, Naiara Perurena, Pablo Ruedas, Thomas Walle, Alberto Pezonaga-Torres, Juan Hinojosa, Elisabeth Guruceaga, Antonio Pineda-Lucena, Marta Abengózar-Muela, Denis Cochonneau, Carolina Zandueta, Susana Martínez-Canarias, Alvaro Teijeira, Daniel Ajona, Sergio Ortiz Espinosa, Xabier Morales, Carlos Ortiz de Solórzano, Marta Santisteban, Luis I Ramos-García, Laura Guembe, Vratislav Strnad, Dominique Heymann, Sandra Hervás-Stubbs, Ruben Pio, María E Rodríguez-Ruiz, Carlos E de Andrea, Silvestre Vincent, Ignacio Melero Bermejo, Fernando Lecanda, Rafael Martinez-Monge
Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer. Cancer discovery 12 (5) (2022)
Tim F Greten, Ghassan K Abou-Alfa, Ann-Lii Cheng, Austin G Duffy, Anthony B El-Khoueiry, Richard S Finn, Peter R Galle, Lipika Goyal, Aiwu Ruth He, Ahmed O Kaseb, Robin Kate Kelley, Riccardo Lencioni, Amaia Lujambio, Donna Mabry Hrones, David James Pinato, Bruno Sangro, Roberto I Troisi, Andrea Wilson Woods, Thomas Yau, Andrew X Zhu, Ignacio Melero Bermejo
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of hepatocellular carcinoma. Journal for immunotherapy of cancer 9 (9) (2022)
Enrique Conde, Enric Vercher, Marta Soria-Castellano, Jesús Suarez-Olmos, Uxua Mancheño, Edurne Elizalde, M Luis Rodriguez, Javier Glez-Vaz, Noelia Casares, Estefanía Rodríguez-García, Mirja Hommel, Gloria González-Aseguinolaza, Iratxe Uranga-Murillo, Julian Pardo, Gorka Alkorta, Ignacio Melero Bermejo, Juan Jose Lasarte, Sandra Hervás-Stubbs
Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants. Journal for immunotherapy of cancer 9 (11) (2022)
Alexander Muik, Elena Garralda, Isil Altintas, Friederike Gieseke, Ravit Geva, Eytan Ben-Ami, Corinne Maurice-Dror, Emiliano Calvo, Patricia M LoRusso, Guzman Alonso, Maria E Rodriguez-Ruiz, Kristina B Schoedel, Jordan M Blum, Bianca Sänger, Theodora W Salcedo, Saskia M Burm, Eliana Stanganello, Dennis Verzijl, Fulvia Vascotto, Angelica Sette, Juliane Quinkhardt, Theo S Plantinga, Aras Toker, Edward N van den Brink, Mark Fereshteh, Mustafa Diken, David Satijn, Sebastian Kreiter, Esther C W Breij, Gaurav Bajaj, Eleni Lagkadinou, Kate Sasser, Özlem Türeci, Ulf Forssmann, Tahamtan Ahmadi, Uğur Şahin, Maria Jure-Kunkel, Ignacio Melero Bermejo
Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors. Cancer discovery 12 (5) (2022)
Alvaro Teijeira, Saray Garasa, Carlos Luri-Rey, Carlos E De Andrea, Maria Gato-Cañas, Carmen Molina, Tsuneyasu Kaisho, Assunta Cirella, Arantza Azpilikueta, Steffanie K Wculek, Josune Egea, Irene Olivera, Inmaculada Rodriguez, Ana Rouzaut, Vladislav V Verkhusha, Karmele Valencia, David Sancho, Pedro Berraondo, Ignacio Melero Bermejo
Depletion of Conventional Type-1 Dendritic Cells in Established Tumors Suppresses Immunotherapy Efficacy. Cancer research 82 (23) (2022)
Fernando Aranda, Iñaki Eguren, Ángela Bella, Pedro Berraondo, Ignacio Melero Bermejo
Revisiting Intracavitary Immunotherapy of Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (10) (2022)
Irene Olivera, Vicente Martín, Elixabet Bolaños, Inmaculada Rodriguez, Iñaki Etxeberría, Assunta Cirella, Josune Egea, Saray Garasa, Itziar Migueliz, Iñaki Eguren, Miguel F Sanmamed, Javier Glez-Vaz, Arantza Azpilikueta, Maite Alvarez, María Carmen Ochoa, Beatrice Malacrida, David J Propper, Carlos E De Andrea, Pedro Berraondo, Frances R Balkwill, Alvaro Teijeira, Ignacio Melero Bermejo
A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1β. Cancer discovery 12 (9) (2022)
Shirley Tenesaca, Marcos Vasquez, Maite Alvarez, Itziar Otano, Myriam Fernandez-Sendin, Claudia Augusta Di Trani, Nuria Ardaiz, Celia Gomar, Angela Bella, Fernando Aranda, José Medina-Echeverz, Ignacio Melero Bermejo, Pedro Berraondo
Statins act as transient type I interferon inhibitors to enable the antitumor activity of modified vaccinia Ankara viral vectors. Journal for immunotherapy of cancer 9 (7) (2022)
Assunta Cirella, Elixabet Bolaños, Claudia Augusta Di Trani, Carlos E De Andrea, Sandra Sanchez-Gregorio, Iñaki Etxeberría, Jose Gonzalez-Gomariz, Irene Olivera, Davide Brocco, Javier Glez-Vaz, Carlos Luri-Rey, Arantza Azpilikueta, Inmaculada Rodriguez, Myriam Fernandez-Sendin, Josune Egea, Iñaki Eguren, Miguel F Sanmamed, Belen Palencia, Alvaro Teijeira, Pedro Berraondo, Ignacio Melero Bermejo
Intratumoral gene transfer of mRNAs encoding interleukin-12 in combination with decoy-resistant interleukin-18 improves local and systemic antitumor immunity. Cancer immunology research (2022)
Francisco J Cueto, Carlos Del Fresno Sánchez, Paola Brandi, Alexis J Combes, Elena Hernández-García, Alfonso R Sánchez-Paulete, Michel Enamorado, Christian P Bromley, Manuel J Jose Gómez, Ruth Conde-Garrosa, Santos Mañes, Santiago Zelenay, Ignacio Melero Bermejo, Salvador Iborra, Matthew F Krummel, David Sancho
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells. Journal for immunotherapy of cancer 9 (5) (2022)
Matthew J Lin, Judit Svensson-Arvelund, Gabrielle S Lubitz, Aurélien Marabelle, Ignacio Melero Bermejo, Brian D Brown, Joshua D Brody
Cancer vaccines: the next immunotherapy frontier. Nature cancer 3 (8) (2022)
Iñaki Etxeberría, Elixabet Bolaños, Alvaro Teijeira, Saray Garasa, Alba Yanguas, Arantza Azpilikueta, William M Kavanaugh, Olga Vasiljeva, Marcia Belvin, Bruce Howng, Bryan Irving, Kimberly Tipton, James West, Li Mei, Alan J Korman, Emanuela Sega, Irene Olivera, Assunta Cirella, María Carmen Ochoa, Maria E Rodríguez-Ruiz, Ana Melero, Miguel F Sanmamed, John J Engelhardt, Ignacio Melero Bermejo
Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic. Proceedings of the National Academy of Sciences of the United States of America 118 (26) (2021)
Ángela Bella, Claudia Augusta Di Trani, Myriam Fernandez-Sendin, Leire Arrizabalaga, Assunta Cirella, Alvaro Teijeira, José Medina-Echeverz, Ignacio Melero Bermejo, Pedro Berraondo, Fernando Aranda
Mouse Models of Peritoneal Carcinomatosis to Develop Clinical Applications. Cancers 13 (5) (2021)
Maite Alvarez, Carmen Molina, Carlos E De Andrea, Myriam Fernandez-Sendin, Maria Villalba, Jose Gonzalez-Gomariz, Maria Carmen Ochoa, Alvaro Teijeira, Javier Glez-Vaz, Fernando Aranda, Miguel F Sanmamed, Maria E Rodriguez-Ruiz, Xinyi Fan, Wen H Shen, Pedro Berraondo, Marisol Quintero, Ignacio Melero Bermejo
Intratumoral co-injection of the poly I:C-derivative BO-112 and a STING agonist synergize to achieve local and distant anti-tumor efficacy. Journal for immunotherapy of cancer 9 (11) (2021)
Maria Hinterberger, Raphael Giessel, Giovanna Fiore, Fabienne Graebnitz, Barbara Bathke, Sonia Wennier, Paul Chaplin, Ignacio Melero Bermejo, Mark Suter, Henning Lauterbach, Pedro Berraondo, Hubertus Hochrein, José Medina-Echeverz
Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory. Journal for immunotherapy of cancer 9 (2) (2021)
Ignacio Melero Bermejo, Eduardo Castanon, Maite Alvarez, Stephane Champiat, Aurélien Marabelle
Intratumoural administration and tumour tissue targeting of cancer immunotherapies. Nature reviews. Clinical oncology 18 (9) (2021)
Alvaro Teijeira, Saray Garasa, Maria Del Carmen Ochoa, Assunta Cirella, Irene Olivera, Javier Glez-Vaz, Maria Pilar Andueza, Itziar Migueliz, Maite Alvarez, Maria Esperanza Rodríguez-Ruiz, Ana Rouzaut, Pedro Berraondo, Miguel F Sanmamed, Jose L Perez Gracia, Ignacio Melero Bermejo
Differential Interleukin-8 thresholds for chemotaxis and netosis in human neutrophils. European journal of immunology 51 (9) (2021)
Bruno Sangro, Pablo Sarobe, Sandra Hervás-Stubbs, Ignacio Melero Bermejo
Advances in immunotherapy for hepatocellular carcinoma. Nature reviews. Gastroenterology & hepatology 18 (8) (2021)
Itziar Otano, Arantza Azpilikueta, Javier Glez-Vaz, Maite Alvarez, José Medina-Echeverz, Ivan Cortés-Domínguez, Carlos Ortiz de Solórzano, Peter Ellmark, Sara Fritzell, Gabriela Hernandez-Hoyos, Michelle Hase Nelson, María Carmen Ochoa, Elixabet Bolaños, Doina Cuculescu, Patricia Jaúregui, Sandra Sanchez-Gregorio, Iñaki Etxeberría, María E Rodriguez-Ruiz, Miguel F Sanmamed, Álvaro Teijeira, Pedro Berraondo, Ignacio Melero Bermejo
CD137 (4-1BB) costimulation of CD8 + T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation. Nature communications 12 (1) (2021)
Luna Minute, Alvaro Teijeira, Alfonso R Sanchez-Paulete, Maria C Ochoa, Maite Alvarez, Itziar Otano, Iñaki Etxeberrria, Elixabet Bolaños, Arantza Azpilikueta, Saray Garasa, Noelia Casares, Jose Luis Perez Gracia, Maria E Rodriguez-Ruiz, Pedro Berraondo, Ignacio Melero Bermejo
Cellular cytotoxicity is a form of immunogenic cell death. Journal for immunotherapy of cancer 8 (1) (2020)
Kurt A Schalper, Michael Carleton, Paul Statkevich, Tian Chen, Ye Feng, Shu-Pang Huang, Alice M Walsh, Vipul Baxi, Dimple Pandya, Timothy Baradet, Darren Locke, Qiuyan Wu, Timothy P Reilly, Penny Phillips, Venkata Nagineni, Nicole Gianino, Jianlei Gu, Hongyu Zhao, Jose Luis Perez-Gracia, Miguel F Sanmamed, Ignacio Melero Bermejo
Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors. Nature medicine 26 (5) (2020)
M Angela Aznar, Lourdes Planelles, Mercedes Perez-Olivares, Carmen Molina, Saray Garasa, Iñaki Etxeberría, Guiomar Perez, Inmaculada Rodriguez, Elixabet Bolaños, Pedro Lopez-Casas, Maria E Rodriguez-Ruiz, Jose L Perez-Gracia, Ivan Marquez-Rodas, Alvaro Teijeira, Marisol Quintero, Ignacio Melero Bermejo
Immunotherapeutic effects of intratumoral nanoplexed poly I:C. Journal for immunotherapy of cancer 7 (1) (2019)
Maria Angela Aznar, Carmen Molina, Alvaro Teijeira, Inmaculada Rodriguez, Arantza Azpilikueta, Saray Garasa, Alfonso R Sanchez-Paulete, Luna Cordeiro, Iñaki Etxeberria, Maite Alvarez, Sergio Rius-Rocabert, Estanislao Nistal-Villan, Pedro Berraondo, Ignacio Melero Bermejo
Repurposing the yellow fever vaccine for intratumoral immunotherapy. EMBO molecular medicine 12 (1) (2019)
Kurt A Schalper, Maria E Rodriguez-Ruiz, Ricardo Diez-Valle, Alvaro López-Janeiro, Angelo Porciuncula, Miguel A Idoate, Susana Inogés, Carlos de Andrea, Ascensión López-Diaz de Cerio, Sonia Tejada, Pedro Berraondo, Franz Villarroel-Espindola, Jungmin Choi, Alfonso Gúrpide, Miriam Giraldez, Iosune Goicoechea, Jaime Gállego Pérez-Larraya, Miguel F Sanmamed, Jose-Luis Perez-Gracia, Ignacio Melero Bermejo
Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma. Nature medicine 25 (3) (2019)
Pedro Berraondo, Maria Angela Aznar, Elisabeth Perez-Ruiz, Maria Esperanza Rodriguez-Ruiz, Eduardo Castañon, Jose-Luis Perez-Gracia, Ignacio Melero Bermejo
International Symposium: Trailblazing in Cancer Immunotherapy, October 29-31, 2017, Pamplona, Spain. Cancer immunology, immunotherapy : CII 67 (11) (2018)