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Christian Steinebach

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 23

Top Venues

Pharmaceutics

Journal of medicinal chemistry

RSC chemical biology

Nature communications

University of Bonn (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

University of Bonn Aug 1o 2016

Germany

PHD :: Pharmaceutical Institute

Publications

Christian Steinebach, Aleša Bricelj, Arunima Murgai, Gobec Izidor Sosič, Luca Bischof, Yuen Lam Dora Ng, Christopher Heim, Samuel Maiwald, Matic Proj, Rabea Voget, Felix Feller, Janez Košmrlj, Valeriia Sapozhnikova, Annika Schmidt, Maximilian Rudolf Zuleeg, Patricia Lemnitzer, Philipp Mertins, Finn K Hansen, Michael Gütschow, Jan Krönke, Marcus D Hartmann
Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. Journal of medicinal chemistry (2023)
Yuen Lam Dora Ng, Aleša Bricelj, Jacqueline A Jansen, Arunima Murgai, Kirsten Peter, Katherine A Donovan, Michael Gütschow, Jan Krönke, Christian Steinebach, Gobec Izidor Sosič
Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins. Journal of medicinal chemistry (2023)
Robert Kuchta, Christopher Heim, Alexander Herrmann, Samuel Maiwald, Yuen Lam Dora Ng, Gobec Izidor Sosič, Tim Keuler, Jan Krönke, Michael Gütschow, Marcus D Hartmann, Christian Steinebach
Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC chemical biology 4 (3) (2023)
Robert Kuchta, Christopher Heim, Alexander Herrmann, Samuel Maiwald, Yuen Lam Dora Ng, Gobec Izidor Sosič, Tim Keuler, Jan Krönke, Michael Gütschow, Marcus D Hartmann, Christian Steinebach
Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC chemical biology 4 (3) (2023)
Lan Phuong Vu, Claudia J Diehl, Ryan Casement, Adam G Bond, Christian Steinebach, Nika Strašek, Aleša Bricelj, Andrej Perdih, Gregor Schnakenburg, Gobec Izidor Sosič, Alessio Ciulli, Michael Gütschow
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers. Journal of medicinal chemistry (2023)
Florian Pöstges, Kevin Kayser, Jan Appelhaus, Marius Monschke, Michael Gütschow, Christian Steinebach, Karl G Wagner
Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs. Pharmaceutics 15 (1) (2023)
Florian Pöstges, Kevin Kayser, Jan Appelhaus, Marius Monschke, Michael Gütschow, Christian Steinebach, Karl G Wagner
Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs. Pharmaceutics 15 (1) (2023)
Florian Pöstges, Kevin Kayser, Jan Appelhaus, Marius Monschke, Michael Gütschow, Christian Steinebach, Karl G Wagner
Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs. Pharmaceutics 15 (1) (2023)
Florian Pöstges, Kevin Kayser, Jan Appelhaus, Marius Monschke, Michael Gütschow, Christian Steinebach, Karl G Wagner
Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs. Pharmaceutics 15 (1) (2023)
Bianca Schulte, Maria König, Beate I Escher, Sophie Wittenburg, Matic Proj, Valentina Wolf, Carina Lemke, Gregor Schnakenburg, Gobec Izidor Sosič, Hendrik Streeck, Christa Elisabeth Müller, Michael Gütschow, Christian Steinebach
Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti-SARS-CoV-2 Activity. ChemMedChem 17 (5) (2022)
Lukas M Gockel, Vladlena Pfeifer, Fabian Baltes, Rafael D Bachmaier, Karl G Wagner, Gerd Bendas, Michael Gütschow, Izidor Sosič, Christian Steinebach
Design, synthesis, and characterization of PROTACs targeting the androgen receptor in prostate and lung cancer models. Archiv der Pharmazie 355 (5) (2022)
Arunima Murgai, Gobec Izidor Sosič, Martina Gobec, Patricia Lemnitzer, Matic Proj, Sophie Wittenburg, Rabea Voget, Michael Gütschow, Jan Krönke, Christian Steinebach
Targeting the deubiquitinase USP7 for degradation with PROTACs. Chemical communications (Cambridge, England) 58 (63) (2022)
Gobec Izidor Sosič, Aleša Bricelj, Christian Steinebach
E3 ligase ligand chemistries: from building blocks to protein degraders. Chemical Society reviews 51 (9) (2022)
Daniel S J Miller, Sabine A Voell, Gobec Izidor Sosič, Matic Proj, Olivia W Rossanese, Gregor Schnakenburg, Michael Gütschow, Ian Collins, Christian Steinebach
Encoding BRAF inhibitor functions in protein degraders. RSC medicinal chemistry 13 (6) (2022)
Yuen Lam Dora Ng, Evelyn Ramberger, Stephan R Bohl, Anna Dolnik, Christian Steinebach, Theresia Conrad, Sina Müller, Oliver Popp, Miriam Kull, Mohamed Haji, Michael Gütschow, Hartmut Döhner, Wolfgang Walther, Ulrich Bernd Keller, Lars Bullinger, Philipp Mertins, Jan Krönke
Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma. Nature communications 13 (1) (2022)
Tim Keuler, Beate König, Nico Bückreiß, Fabian B Kraft, Philipp König, Linda Schäker-Hübner, Christian Steinebach, Gerd Bendas, Michael Gütschow, Finn K Hansen
Development of the first non-hydroxamate selective HDAC6 degraders. Chemical communications (Cambridge, England) 58 (79) (2022)
Wulf Tonnus, Claudia Meyer, Christian Steinebach, Alexia Belavgeni, Anne von Mässenhausen, Nadia Zamora Gonzalez, Francesca Maremonti, Florian Gembardt, Nina Himmerkus, Markus Latk, Sophie Locke, Julian Marschner, Wenjun Li, Spencer Short, Sebastian Doll, Irina Ingold, Bettina Proneth, Christoph Daniel, Nazanin Kabgani, Rafael Kramann, Stephen Motika, Paul J Hergenrother, Stefan R Bornstein, Christian Hugo, Jan Ulrich Becker, Kerstin Amann, Hans-Joachim Anders, Daniel Kreisel, Derek A Pratt, Michael Gütschow, Marcus Conrad, Andreas Linkermann
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury. Nature communications 12 (1) (2021)
Izidor Sosič, Martina Gobec, Christian Steinebach, Martin Schlesinger, Gerd Bendas, Michael Gütschow
Another structural correction for 1-oxo-1H-phenalene-2,3-dicarbonitriles: Synthesis of a potent BCL-2 inhibiting 7-phenoxy derivative. Archiv der Pharmazie 354 (10) (2021)
Aleša Bricelj, Yuen Lam Dora Ng, Dominic Ferber, Robert Kuchta, Sina Müller, Marius Monschke, Karl G Wagner, Jan Krönke, Gobec Izidor Sosič, Michael Gütschow, Christian Steinebach
Influence of Linker Attachment Points on the Stability and Neosubstrate Degradation of Cereblon Ligands. ACS medicinal chemistry letters 12 (11) (2021)
Christian Steinebach, Yuen Lam Dora Ng, Gobec Izidor Sosič, Chih-Shia Lee, Sirui Chen, Stefanie Lindner, Lan Phuong Vu, Aleša Bricelj, Reza Haschemi, Marius Monschke, Elisabeth Steinwarz, Karl G Wagner, Gerd Bendas, Ji Luo, Michael Gütschow, Jan Krönke
Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders. Chemical science 11 (13) (2020)
Megan L Peach, Shaunna L Beedie, Cindy H Chau, Matthew K Collins, Suzana Markolovic, Weiming Luo, David Tweedie, Christian Steinebach, Nigel H Greig, Michael Gütschow, Neil Vargesson, Marc C Nicklaus, William Douglas Figg
Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs. Molecules (Basel, Switzerland) 25 (23) (2020)
Anna K Krome, Tim Becker, Stefan Kehraus, Andrea Schiefer, Christian Steinebach, Tilman Aden, Stefan J Frohberger, Álvaro López Mármol, Dnyaneshwar Kapote, Rolf Jansen, Lillibeth Chaverra-Muñoz, Marc P Hübner, Kenneth M Pfarr, Thomas Hesterkamp, Marc Stadler, Michael Gütschow, Gabriele M König, Achim Hoerauf, Karl G Wagner
Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A. Pharmaceutics 12 (11) (2020)
Christian Steinebach, Gobec Izidor Sosič, Stefanie Lindner, Aleša Bricelj, Franziska Kohl, Yuen Lam Dora Ng, Marius Monschke, Karl G Wagner, Jan Krönke, Michael Gütschow
A MedChem toolbox for cereblon-directed PROTACs. MedChemComm 10 (6) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christian Steinebach