Florian Markowetz

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 39

Top Venues

Genome biology

eLife

Nature communications

Nature genetics

University of Cambridge

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Cambridge Jan 01 2009

United Kingdom

Group leader :: Cancer Research UK Cambridge Institute

Princeton University Jul 01 2006 - Dec 31 2008

United States

Postdoc :: Lewis-Sigler Institute for Integrative Genomics

Max Planck Institute for Molecular Genetics Jan 01 2002 - Jul 01 2006

Germany

PhD student :: Department Computational Biology

Publications

Florian Markowetz
All models are wrong and yours are useless: making clinical prediction models impactful for patients. NPJ precision oncology 8 (1) (2024)
Pelin Icer Baykal, Paweł Piotr Łabaj, Florian Markowetz, Lynn M Schriml, Daniel Johannes Stekhoven, Serghei Mangul, Niko Beerenwinkel
Genomic reproducibility in the bioinformatics era. Genome biology 25 (1) (2024)
Michael P Schneider, Amy E Cullen, Justina Pangonyte, Jason Skelton, Harvey Major, Elke Van Oudenhove, Maria J Garcia, Blas Chaves Urbano, Anna M Piskorz, James D Brenton, Geoff Macintyre, Florian Markowetz
scAbsolute: measuring single-cell ploidy and replication status. Genome biology 25 (1) (2024)
Pelin Icer Baykal, Paweł Piotr Łabaj, Florian Markowetz, Lynn M Schriml, Daniel Johannes Stekhoven, Serghei Mangul, Niko Beerenwinkel
Genomic reproducibility in the bioinformatics era. Genome biology 25 (1) (2024)
Florian Markowetz
All models are wrong and yours are useless: making clinical prediction models impactful for patients. NPJ precision oncology 8 (1) (2024)
Michael P Schneider, Amy E Cullen, Justina Pangonyte, Jason Skelton, Harvey Major, Elke Van Oudenhove, Maria J Garcia, Blas Chaves Urbano, Anna M Piskorz, James D Brenton, Geoff Macintyre, Florian Markowetz
scAbsolute: measuring single-cell ploidy and replication status. Genome biology 25 (1) (2024)
Michael P Schneider, Amy E Cullen, Justina Pangonyte, Jason Skelton, Harvey Major, Elke Van Oudenhove, Maria J Garcia, Blas Chaves Urbano, Anna M Piskorz, James D Brenton, Geoff Macintyre, Florian Markowetz
scAbsolute: measuring single-cell ploidy and replication status. Genome biology 25 (1) (2024)
Pelin Icer Baykal, Paweł Piotr Łabaj, Florian Markowetz, Lynn M Schriml, Daniel Johannes Stekhoven, Serghei Mangul, Niko Beerenwinkel
Genomic reproducibility in the bioinformatics era. Genome biology 25 (1) (2024)
Florian Markowetz
All models are wrong and yours are useless: making clinical prediction models impactful for patients. NPJ precision oncology 8 (1) (2024)
Michael P Schneider, Amy E Cullen, Justina Pangonyte, Jason Skelton, Harvey Major, Elke Van Oudenhove, Maria J Garcia, Blas Chaves Urbano, Anna M Piskorz, James D Brenton, Geoff Macintyre, Florian Markowetz
scAbsolute: measuring single-cell ploidy and replication status. Genome biology 25 (1) (2024)
Michael P Schneider, Amy E Cullen, Justina Pangonyte, Jason Skelton, Harvey Major, Elke Van Oudenhove, Maria J Garcia, Blas Chaves Urbano, Anna M Piskorz, James D Brenton, Geoff Macintyre, Florian Markowetz
scAbsolute: measuring single-cell ploidy and replication status. Genome biology 25 (1) (2024)
Maria Vias, Lena Morrill Gavarró, Carolin Margarethe Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James A Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
High-grade serous ovarian carcinoma organoids as models of chromosomal instability. eLife 12 (2023)
Mireia Crispin-Ortuzar, Ramona Woitek, Marika A V Reinius, Elizabeth Moore, Lucian Beer, Vlad Bura, Leonardo Rundo, Cathal McCague, Stephan Ursprung, Lorena Escudero Sanchez, Paula Martin-Gonzalez, Florent Mouliere, Dineika Chandrananda, James Morris, Teodora Goranova, Anna M Piskorz, Naveena Singh, Anju Sahdev, Roxana Pintican, Marta Zerunian, Nitzan Rosenfeld, Helen Addley, Mercedes Jimenez-Linan, Florian Markowetz, Evis Sala, James D Brenton
Integrated radiogenomics models predict response to neoadjuvant chemotherapy in high grade serous ovarian cancer. Nature communications 14 (1) (2023)
Maria Vias, Lena Morrill Gavarró, Carolin Margarethe Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James A Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
High-grade serous ovarian carcinoma organoids as models of chromosomal instability. eLife 12 (2023)
Maria Vias, Lena Morrill Gavarró, Carolin Margarethe Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James A Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
High-grade serous ovarian carcinoma organoids as models of chromosomal instability. eLife 12 (2023)
Philip S Smith, Thomas Bradley, Lena Morrill Gavarró, Teodora Goranova, Darren P Ennis, Hasan B Mirza, Dilrini De Silva, Anna M Piskorz, Carolin Margarethe Sauer, Sarwah Al-Khalidi, Ionut-Gabriel Funingana, Marika A V Reinius, Gaia Giannone, Liz-Anne Lewsley, Jamie Stobo, John McQueen, Gareth Bryson, Matthew D Eldridge, null null, Geoffrey Macintyre, Florian Markowetz, James D Brenton, Iain A McNeish
Author Correction: The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma. Nature communications 14 (1) (2023)
Philip S Smith, Thomas Bradley, Lena Morrill Gavarró, Teodora Goranova, Darren P Ennis, Hasan B Mirza, Dilrini De Silva, Anna M Piskorz, Carolin Margarethe Sauer, Sarwah Al-Khalidi, Ionut-Gabriel Funingana, Marika A V Reinius, Gaia Giannone, Liz-Anne Lewsley, Jamie Stobo, John McQueen, Gareth Bryson, Matthew D Eldridge, null null, Geoffrey Macintyre, Florian Markowetz, James D Brenton, Iain A McNeish
The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma. Nature communications 14 (1) (2023)
Maria Vias, Lena Morrill Gavarró, Carolin Margarethe Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James A Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
High-grade serous ovarian carcinoma organoids as models of chromosomal instability. eLife 12 (2023)
Maria Vias, Lena Morrill Gavarró, Carolin Margarethe Sauer, Deborah A Sanders, Anna M Piskorz, Dominique-Laurent Couturier, Stéphane Ballereau, Bárbara Hernando, Michael P Schneider, James A Hall, Filipe Correia-Martins, Florian Markowetz, Geoff Macintyre, James D Brenton
High-grade serous ovarian carcinoma organoids as models of chromosomal instability. eLife 12 (2023)
Marek Cmero, Ke Yuan, Cheng Soon Ong, Jan Schröder, null null, Niall M Corcoran, Anthony T Papenfuss, Christopher M Hovens, Florian Markowetz, Geoffrey Macintyre, null null
Author Correction: Inferring structural variant cancer cell fraction. Nature communications 13 (1) (2022)
Ruben M Drews, Barbara Hernando, Maxime Tarabichi, Kerstin Haase, Tom Lesluyes, Philip S Smith, Lena Morrill Gavarró, Dominique-Laurent Couturier, Lydia Y Liu, Michael Schneider, James D Brenton, Peter Van Loo, Geoffrey Macintyre, Florian Markowetz
A pan-cancer compendium of chromosomal instability. Nature 606 (7916) (2022)
Zhao Cheng, Hasan B Mirza, Darren P Ennis, Philip S Smith, Lena Morrill Gavarró, Chishimba Sokota, Gaia Giannone, Theodora Goranova, Thomas Bradley, Anna Piskorz, Michelle Lockley, null null, Baljeet Kaur, Naveena Singh, Laura A Tookman, Jonathan Krell, Jacqueline McDermott, Geoffrey Macintyre, Florian Markowetz, James D Brenton, Iain A McNeish
The Genomic Landscape of Early-Stage Ovarian High-Grade Serous Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (13) (2022)
Ronja S Adam, Dennis Poel, Leandro Ferreira Moreno, Joey M A Spronck, Tim R de Back, Arezo Torang, Patricia M Gomez Barila, Sanne Ten Hoorn, Florian Markowetz, Xin Wang, Henk M W Verheul, Tineke E Buffart, Louis Vermeulen
Development of a miRNA-based classifier for detection of colorectal cancer molecular subtypes. Molecular oncology 16 (14) (2022)
Marcel Gehrung, Mireia Crispin-Ortuzar, Adam G Berman, Maria O'Donovan, Rebecca C Fitzgerald, Florian Markowetz
Triage-driven diagnosis of Barrett's esophagus for early detection of esophageal adenocarcinoma using deep learning. Nature medicine 27 (5) (2021)
Benjamin J Heil, Michael M Hoffman, Florian Markowetz, Su-In Lee, Casey S Greene, Stephanie C Hicks
Reproducibility standards for machine learning in the life sciences. Nature methods 18 (10) (2021)
Edith M Ross, Kerstin Haase, Peter Van Loo, Florian Markowetz
Allele-specific multi-sample copy number segmentation in ASCAT. Bioinformatics (Oxford, England) 37 (13) (2021)
Stephen-John Sammut, Mireia Crispin-Ortuzar, Suet-Feung Chin, Elena Provenzano, Helen A Bardwell, Wenxin Ma, Wei Cope, Ali Dariush, Sarah-Jane Dawson, Jean E Abraham, Janet Dunn, Louise Hiller, Jeremy Thomas, David A Cameron, John M S Bartlett, Larry Hayward, Paul David Peter Pharoah, Florian Markowetz, Oscar M Rueda, Helena M Earl, Carlos Caldas
Multi-omic machine learning predictor of breast cancer therapy response. Nature (2021)
Alejandro Jiménez-Sánchez, Paulina Cybulska, Katherine LaVigne Mager, Simon Koplev, Oliver Cast, Dominique-Laurent Couturier, Danish Memon, Pier Selenica, Ines Nikolovski, Yousef Mazaheri, Yonina Bykov, Felipe C Geyer, Geoffrey Macintyre, Lena Morrill Gavarró, Ruben M Drews, Michael B Gill, Anastasios D Papanastasiou, Ramon E Sosa, Robert A Soslow, Tyler Walther, Ronglai Shen, Dennis S Chi, Kay J Park, Travis Hollmann, Jorge Sergio Reis-Filho, Florian Markowetz, Pedro Beltrao, Hebert Alberto Vargas, Dmitriy Zamarin, James D Brenton, Alexandra Snyder, Britta Weigelt, Evis Sala, Martin L Miller
Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy. Nature genetics 52 (6) (2020)
Marek Cmero, Ke Yuan, Cheng Soon Ong, Jan Schröder, null null, Niall M Corcoran, Anthony T Papenfuss, Christopher M Hovens, Florian Markowetz, Geoffrey Macintyre, null null
Inferring structural variant cancer cell fraction. Nature communications 11 (1) (2020)
Euan S Polson, Verena B Kuchler, Christopher Abbosh, Edith M Ross, Ryan Koshy Mathew, Hester A Beard, Bárbara da Silva, Andrew N Holding, Stephane Ballereau, Eulashini Chuntharpursat-Bon, Jennifer Williams, Hollie B S Griffiths, Hao Shao, Anjana Patel, Adam J Davies, Alastair P Droop, Paul Chumas, Susan C Short, Mihaela Lorger, Jason E Gestwicki, Lee D Roberts, Robin S Bon, Simon J Allison, Shoutian Zhu, Florian Markowetz, Heiko Wurdak
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice. Science translational medicine 10 (454) (2019)
Maxime Tarabichi, Iñigo Martincorena, Moritz Gerstung, Armand M Leroi, Florian Markowetz, null null, Paul T Spellman, Quaid D Morris, Ole Christian Lingjærde, David C Wedge, Peter Van Loo
Neutral tumor evolution? Nature genetics 50 (12) (2019)
Andrew N Holding, Amy E Cullen, Florian Markowetz
Genome-wide Estrogen Receptor-α activation is sustained, not cyclical. eLife 7 (2018)
Geoffrey Macintyre, Teodora E Goranova, Dilrini De Silva, Darren Ennis, Anna M Piskorz, Matthew Eldridge, Daoud Sie, Liz-Anne Lewsley, Aishah Hanif, Cheryl Wilson, Suzanne Dowson, Rosalind M Glasspool, Michelle Lockley, Elly Brockbank, Ana Montes, Axel Walther, Sudha Sundar, Richard Edmondson, Geoff D Hall, Andrew Clamp, Charlie Gourley, Marcia Hall, Christina Fotopoulou, Hani Gabra, James Paul, Anna Supernat, David Millan, Aoisha Hoyle, Gareth Bryson, Craig Nourse, Laura Mincarelli, Luis Navarro Sanchez, Bauke Ylstra, Mercedes Jimenez-Linan, Luiza Moore, Oliver Hofmann, Florian Markowetz, Iain A McNeish, James D Brenton
Copy number signatures and mutational processes in ovarian carcinoma. Nature genetics 50 (9) (2018)
Evangelia K Papachristou, Kamal Kishore, Andrew N Holding, Kate Harvey, Theodoros I Roumeliotis, Chandra Sekhar Reddy Chilamakuri, Soleilmane Omarjee, Kee Ming Chia, Alex Swarbrick, Elgene Lim, Florian Markowetz, Matthew Eldridge, Rasmus Siersbaek, Clive S D'Santos, Jason S Carroll
A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes. Nature communications 9 (1) (2018)
Florian Markowetz
A saltationist theory of cancer evolution. Nature genetics 48 (10) (2017)
Shivan Sivakumar, Ines de Santiago, Leon Chlon, Florian Markowetz
Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis. PLoS medicine 14 (1) (2017)
Ines de Santiago, Wei Liu, Ke Yuan, Martin O'Reilly, Chandra Sekhar Reddy Chilamakuri, Bruce A J Ponder, Kerstin B Meyer, Florian Markowetz
BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes. Genome biology 18 (1) (2017)
Florian Markowetz
All biology is computational biology. PLoS biology 15 (3) (2017)
H Raza Ali, Leon Chlon, Paul D P Pharoah, Florian Markowetz, Carlos Caldas
Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study. PLoS medicine 13 (12) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Florian Markowetz