Gabriela Alexe

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 24

Top Topics

Histone Deacetylase

Acute Myeloid Leukemia

Top Venues

Science advances

Cancer discovery

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma. Science advances 10 (22) (2024)
Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma. Science advances 10 (22) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Constanze Schneider, Hermes Spaink, Gabriela Alexe, Neekesh V Dharia, Ashleigh Meyer, Lucy A Merickel, Delan Khalid, Sebastian Scheich, Bjorn Haupl, Louis M Staudt, Thomas Oellerich, Kimberly Stegmaier
Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia. Cancer research (2024)
Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma. Science advances 10 (22) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma. Science advances 10 (22) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Nathaniel W Mabe, Min Huang, Guillermo N Dalton, Gabriela Alexe, Daniel A Schaefer, Anna C Geraghty, Amanda L Robichaud, Amy S Conway, Delan Khalid, Marius M Mader, Julia A Belk, Kenneth N Ross, Michal Sheffer, Miles H Linde, Nghi Ly, Winnie Yao, Maria Caterina Rotiroti, Benjamin A H Smith, Marius Wernig, Carolyn R Bertozzi, Michelle Monje, Constantine S Mitsiades, Ravindra Majeti, Ansuman T Satpathy, Kimberly Stegmaier, Robbie G Majzner
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1. Nature cancer 3 (8) (2022)
Jana M Ellegast, Gabriela Alexe, Amanda Hamze, Shan Lin, Hannah J Uckelmann, Philipp J Rauch, Maxim Pimkin, Linda S Ross, Neekesh V Dharia, Amanda L Robichaud, Amy Saur Conway, Delan Khalid, Jennifer A Perry, Mark Wunderlich, Lina Benajiba, Yana Pikman, Behnam Nabet, Nathanael S Gray, Stuart H Orkin, Kimberly Stegmaier
Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts. Cancer discovery 12 (7) (2022)
E John Tokarsky, Jesse C Crow, Lillian M Guenther, John Sherman, Cenny Taslim, Gabriela Alexe, Kathleen I Pishas, Galen Rask, Blake S Justis, Ana Kasumova, Kimberly Stegmaier, Stephen L Lessnick, Emily Rose Theisen
Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma. Molecular cancer research : MCR 20 (7) (2022)
Anna Montanaro, Samuel Kitara, Elisa Cerretani, Matteo Marchesini, Chiara Rompietti, Luca Pagliaro, Andrea Gherli, Angela Su, Maria Laura Minchillo, Mariafrancesca Caputi, Rodanthi Fioretzaki, Bruno Lorusso, Linda Ross, Gabriela Alexe, Elena Masselli, Marina Marozzi, Federica Maria Angela Rizzi, Roberta La Starza, Cristina Mecucci, Yan Xiong, Jian Jin, Angela Falco, Birgit Knoechel, Franco Aversa, Olivia Candini, Federico Quaini, Paolo Sportoletti, Kimberly Stegmaier, Giovanni Roti
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia. Cell death & disease 13 (6) (2022)
Bryann Pardieu, Justine Pasanisi, Frank Ling, Reinaldo Dal Bello, Justine Penneroux, Angela Su, Romane Joudinaud, Laureen Chat, Hsin Chieh Wu, Matthieu Duchmann, Gaetano Sodaro, Clémentine Chauvel, Florence A Castelli, Loic Vasseur, Kim Pacchiardi, Yannis Belloucif, Marie-Charlotte Laiguillon, Eshwar Meduri, Camille Vaganay, Gabriela Alexe, Jeannig Berrou, Chaima Benaksas, Antoine Forget, Thorsten Braun, Claude Gardin, Emmanuel Raffoux, Emmanuelle Clappier, Lionel Ades, Hugues de Thé, François Fenaille, Brian James Patrick Huntly, Kimberly Stegmaier, Hervé Dombret, Nina Fenouille, Camille Lobry, Alexandre Puissant, Raphaël A Itzykson
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia. Leukemia 36 (6) (2022)
Clare F Malone, Minjee Kim, Gabriela Alexe, Kathleen L Engel, Alexandra B Forman, Amanda L Robichaud, Amy Saur Conway, Amy Goodale, Ashleigh Meyer, Delan Khalid, Allen Thayakumar, John M Hatcher, Nathanael S Gray, Frederica Piccioni, Kimberly Stegmaier
Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors. Cancer research (2022)
Blandine Roux, Camille Vaganay, Jesse D Vargas, Gabriela Alexe, Chaima Benaksas, Bryann Pardieu, Nina Fenouille, Jana M Ellegast, Edyta Malolepsza, Frank Ling, Gaetano Sodaro, Linda Ross, Yana Pikman, Amy Saur Conway, Yangzhong Tang, Tony Wu, Daniel J Anderson, Ronan Le Moigne, Han-Jie Zhou, Frédéric Luciano, Christina R Hartigan, Ilene Galinsky, Daniel J DeAngelo, Richard M Stone, Patrick Auberger, Monica Schenone, Steven A Carr, Josée Guirouilh-Barbat, Bernard S Lopez, Mehdi Khaled, Kasper Lage, Olivier Hermine, Michael T Hemann, Alexandre Puissant, Kimberly Stegmaier, Lina Benajiba
Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. Science translational medicine 13 (587) (2021)
Angela Su, Frank Ling, Camille Vaganay, Gaetano Sodaro, Chaïma Benaksas, Reinaldo Dal Bello, Antoine Forget, Bryann Pardieu, Kevin H Lin, Justine C Rutter, Christopher F Bassil, Gael Fortin, Justine Pasanisi, Iléana Antony-Debré, Gabriela Alexe, Jean-François Benoist, Alain Pruvost, Yana Pikman, Jun Qi, Marie-Hélène Schlageter, Jean-Baptiste Micol, Giovanni Roti, Thomas Cluzeau, Hervé Dombret, Claude Preudhomme, Nina Fenouille, Lina Benajiba, Hava M Golan, Kimberly Stegmaier, Camille Lobry, Kris C Wood, Raphael Itzykson, Alexandre Puissant
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies. Cancer discovery 10 (12) (2020)
Anjali Cremer, Jana M Ellegast, Gabriela Alexe, Elizabeth S Frank, Linda Ross, S Haihua Chu, Yana Pikman, Amanda Robichaud, Amy Goodale, Björn Häupl, Sebastian Mohr, Arati V Rao, Alison R Walker, James S Blachly, Federica Piccioni, Scott A Armstrong, John C Byrd, Thomas Oellerich, Kimberly Stegmaier
Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia. Cancer discovery 10 (2) (2019)
Florence F Wagner, Lina Benajiba, Arthur J Campbell, Michel Weïwer, Joshua R Sacher, Jennifer P Gale, Linda Ross, Alexandre Puissant, Gabriela Alexe, Amy Saur Conway, Morgan Back, Yana Pikman, Ilene Galinsky, Daniel J DeAngelo, Richard M Stone, Taner Kaya, Xi Shi, Matthew B Robers, Thomas Machleidt, Jennifer Wilkinson, Olivier Hermine, Andrew L Kung, Adam J Stein, Damodharan Lakshminarasimhan, Michael T Hemann, Edward Scolnick, Yan-Ling Zhang, Jen Q Pan, Kimberly Stegmaier, Edward B Holson
Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science translational medicine 10 (431) (2019)
Sarah Wang, Elizabeth E Hwang, Rajarshi Guha, Allison F O'Neill, Nicole Melong, Chansey J Veinotte, Amy Conway Saur, Kellsey Wuerthele, Min Shen, Crystal McKnight, Gabriela Alexe, Madeleine E Lemieux, Amy Wang, Emma Hughes, Xin Xu, Matthew B Boxer, Matthew D Hall, Andrew Kung, Jason N Berman, Mindy I Davis, Kimberly Stegmaier, Brian D Crompton
High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (14) (2019)
Björn Stolte, Amanda Balboni Iniguez, Neekesh V Dharia, Amanda L Robichaud, Amy Saur Conway, Ann M Morgan, Gabriela Alexe, Nathan J Schauer, Xiaoxi Liu, Gregory H Bird, Aviad Tsherniak, Francisca Vazquez, Sara J Buhrlage, Loren D Walensky, Kimberly Stegmaier
Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma. The Journal of experimental medicine 215 (8) (2018)