Kimberly Stegmaier

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 48

Top Topics

Acute Myeloid Leukemia

Allogeneic Hematopoietic Stem Cell Transplantation

Histone Deacetylase

Gene Expression

Top Venues

Nature cell biology

Science advances

Communications biology

This page only lists publications with an associated author ORCID identifier.

Publications

Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma. Science advances 10 (22) (2024)
Nathaniel W Mabe, Jennifer A Perry, Clare F Malone, Kimberly Stegmaier
Pharmacological targeting of the cancer epigenome. Nature cancer 5 (6) (2024)
Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma. Science advances 10 (22) (2024)
Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia (2024)
Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Constanze Schneider, Hermes Spaink, Gabriela Alexe, Neekesh V Dharia, Ashleigh Meyer, Lucy A Merickel, Delan Khalid, Sebastian Scheich, Bjorn Haupl, Louis M Staudt, Thomas Oellerich, Kimberly Stegmaier
Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia. Cancer research (2024)
Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma. Science advances 10 (22) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Clare F Malone, Nathaniel W Mabe, Alexandra B Forman, Gabriela Alexe, Kathleen L Engel, Ying-Jiun C Chen, Melinda Soeung, Silvi Salhotra, Allen Basanthakumar, Bin Liu, Sharon Y R Dent, Kimberly Stegmaier
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma. Science advances 10 (22) (2024)
Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Shan Lin, Constanze Schneider, Angela H Su, Gabriela Alexe, David E Root, Kimberly Stegmaier
The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia. Leukemia 38 (3) (2024)
Clement Larrue, Sarah Mouche, Shan Lin, Federico Simonetta, Nastassja K Scheidegger, Laury Poulain, Rudy Birsen, Jean-Emmanuel Sarry, Kimberly Stegmaier, Jérome Tamburini
Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia. Leukemia (2023)
Diana Y Lu, Jana M Ellegast, Kenneth N Ross, Clare F Malone, Shan Lin, Nathaniel W Mabe, Neekesh V Dharia, Ashleigh Meyer, Amy Conway, Angela H Su, Julia Selich-Anderson, Cenny Taslim, Andrea K Byrum, Bo Kyung A Seong, Biniam Adane, Nathanael S Gray, Miguel N Rivera, Stephen L Lessnick, Kimberly Stegmaier
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology (2023)
Narek Darabedian, Wenzhi Ji, Mengyang Fan, Shan Lin, Hyuk-Soo Seo, Ekaterina V Vinogradova, Tomer M Yaron, Evanna L Mills, Haopeng Xiao, Kristine Senkane, Emily M Huntsman, Jared L Johnson, Jianwei Che, Lewis C Cantley, Benjamin F Cravatt, Sirano Dhe-Paganon, Kimberly Stegmaier, Tinghu Zhang, Nathanael S Gray, Edward T Chouchani
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nature chemical biology (2023)
Diana Y Lu, Jana M Ellegast, Kenneth N Ross, Clare F Malone, Shan Lin, Nathaniel W Mabe, Neekesh V Dharia, Ashleigh Meyer, Amy Conway, Angela H Su, Julia Selich-Anderson, Cenny Taslim, Andrea K Byrum, Bo Kyung A Seong, Biniam Adane, Nathanael S Gray, Miguel N Rivera, Stephen L Lessnick, Kimberly Stegmaier
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology 25 (2) (2023)
Diana Y Lu, Jana M Ellegast, Kenneth N Ross, Clare F Malone, Shan Lin, Nathaniel W Mabe, Neekesh V Dharia, Ashleigh Meyer, Amy Conway, Angela H Su, Julia Selich-Anderson, Cenny Taslim, Andrea K Byrum, Bo Kyung A Seong, Biniam Adane, Nathanael S Gray, Miguel N Rivera, Stephen L Lessnick, Kimberly Stegmaier
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology 25 (2) (2023)
Diana Y Lu, Jana M Ellegast, Kenneth N Ross, Clare F Malone, Shan Lin, Nathaniel W Mabe, Neekesh V Dharia, Ashleigh Meyer, Amy Conway, Angela H Su, Julia Selich-Anderson, Cenny Taslim, Andrea K Byrum, Bo Kyung A Seong, Biniam Adane, Nathanael S Gray, Miguel N Rivera, Stephen L Lessnick, Kimberly Stegmaier
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology 25 (2) (2023)
Narek Darabedian, Wenzhi Ji, Mengyang Fan, Shan Lin, Hyuk-Soo Seo, Ekaterina V Vinogradova, Tomer M Yaron, Evanna L Mills, Haopeng Xiao, Kristine Senkane, Emily M Huntsman, Jared L Johnson, Jianwei Che, Lewis C Cantley, Benjamin F Cravatt, Sirano Dhe-Paganon, Kimberly Stegmaier, Tinghu Zhang, Nathanael S Gray, Edward T Chouchani
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nature chemical biology (2023)
Yeying Huang, R Taylor Durall, Nhi M Luong, Hans J Hertzler, Julianna Huang, Prafulla C Gokhale, Brittaney A Leeper, Nicole S Persky, David E Root, Praju Vikas Anekal, Paula Montero Llopis, Clement N David, Jeffery L Kutok, Alejandra Raimondi, Karan Saluja, Jia Luo, Cynthia A Zahnow, Biniam Adane, Kimberly Stegmaier, Catherine E Hawkins, Christopher Ponne, Quan Le, Geoffrey I Shapiro, Madeleine E Lemieux, Kyle P Eagen, Christopher A French
EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes. Cancer research (2023)
Diana Y Lu, Jana M Ellegast, Kenneth N Ross, Clare F Malone, Shan Lin, Nathaniel W Mabe, Neekesh V Dharia, Ashleigh Meyer, Amy Conway, Angela H Su, Julia Selich-Anderson, Cenny Taslim, Andrea K Byrum, Bo Kyung A Seong, Biniam Adane, Nathanael S Gray, Miguel N Rivera, Stephen L Lessnick, Kimberly Stegmaier
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology 25 (2) (2023)
Rajendran Sanalkumar, Rui Dong, Lukuo Lee, Yu-Hang Xing, Sowmya Iyer, Igor Letovanec, Stefano La Rosa, Giovanna Finzi, Elettra Musolino, Roberto Papait, Ivan A Chebib, G Petur Nielsen, Raffaele Renella, Gregory M Cote, Edwin Choy, Martin J Aryee, Kimberly Stegmaier, Ivan Stamenkovic, Miguel N Rivera, Nicolò Riggi
Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity. Science advances 9 (13) (2023)
Jonathan D Paolino, Boris Dimitrov, Beth Apsel Winger, Angélica Sandoval-Pérez, Amith Vikram Rangarajan, Nicole Ocasio-Martinez, Harrison K Tsai, Yuting Li, Amanda L Robichaud, Delan Khalid, Charles Hatton, Riaz Gillani, Petri Polonen, Anthony Dilig, Giacomo Gotti, Julia Kavanagh, Asmani A Adhav, Sean Gow, Jonathan M Tsai, Yen-Der Li, Benjamin L Ebert, Eliezer Van Allen, Jacob R Bledsoe, Annette S Kim, Sarah K Tasian, Stacy L Cooper, Todd M Cooper, Nobuko Hijiya, Maria-Luisa Sulis, Neerav N Shukla, Jeffrey A Magee, Charles G Mullighan, Michael J Burke, Marlise R Luskin, Brenton G Mar, Matthew P Jacobson, Marian H Harris, Kimberly Stegmaier, Andrew E Place, Yana Pikman
Integration of genomic sequencing drives therapeutic targeting of PDGFRA in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Diana Y Lu, Jana M Ellegast, Kenneth N Ross, Clare F Malone, Shan Lin, Nathaniel W Mabe, Neekesh V Dharia, Ashleigh Meyer, Amy Conway, Angela H Su, Julia Selich-Anderson, Cenny Taslim, Andrea K Byrum, Bo Kyung A Seong, Biniam Adane, Nathanael S Gray, Miguel N Rivera, Stephen L Lessnick, Kimberly Stegmaier
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology 25 (2) (2023)
Clement Larrue, Sarah Mouche, Shan Lin, Federico Simonetta, Nastassja K Scheidegger, Laury Poulain, Rudy Birsen, Jean-Emmanuel Sarry, Kimberly Stegmaier, Jérome Tamburini
Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia. Leukemia (2023)
Rajendran Sanalkumar, Rui Dong, Lukuo Lee, Yu-Hang Xing, Sowmya Iyer, Igor Letovanec, Stefano La Rosa, Giovanna Finzi, Elettra Musolino, Roberto Papait, Ivan A Chebib, G Petur Nielsen, Raffaele Renella, Gregory M Cote, Edwin Choy, Martin J Aryee, Kimberly Stegmaier, Ivan Stamenkovic, Miguel N Rivera, Nicolò Riggi
Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity. Science advances 9 (13) (2023)
Diana Y Lu, Jana M Ellegast, Kenneth N Ross, Clare F Malone, Shan Lin, Nathaniel W Mabe, Neekesh V Dharia, Ashleigh Meyer, Amy Conway, Angela H Su, Julia Selich-Anderson, Cenny Taslim, Andrea K Byrum, Bo Kyung A Seong, Biniam Adane, Nathanael S Gray, Miguel N Rivera, Stephen L Lessnick, Kimberly Stegmaier
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology 25 (2) (2023)
Diana Y Lu, Jana M Ellegast, Kenneth N Ross, Clare F Malone, Shan Lin, Nathaniel W Mabe, Neekesh V Dharia, Ashleigh Meyer, Amy Conway, Angela H Su, Julia Selich-Anderson, Cenny Taslim, Andrea K Byrum, Bo Kyung A Seong, Biniam Adane, Nathanael S Gray, Miguel N Rivera, Stephen L Lessnick, Kimberly Stegmaier
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma. Nature cell biology (2023)
Nathaniel W Mabe, Min Huang, Guillermo N Dalton, Gabriela Alexe, Daniel A Schaefer, Anna C Geraghty, Amanda L Robichaud, Amy S Conway, Delan Khalid, Marius M Mader, Julia A Belk, Kenneth N Ross, Michal Sheffer, Miles H Linde, Nghi Ly, Winnie Yao, Maria Caterina Rotiroti, Benjamin A H Smith, Marius Wernig, Carolyn R Bertozzi, Michelle Monje, Constantine S Mitsiades, Ravindra Majeti, Ansuman T Satpathy, Kimberly Stegmaier, Robbie G Majzner
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1. Nature cancer 3 (8) (2022)
Kenneth Eagle, Taku Harada, Jérémie Kalfon, Monika W Perez, Yaser Heshmati, Jazmin Ewers, Jošt Vrabič Koren, Joshua M Dempster, Guillaume Kugener, Vikram R Paralkar, Charles Y Lin, Neekesh V Dharia, Kimberly Stegmaier, Stuart H Orkin, Maxim Pimkin
Transcriptional Plasticity Drives Leukemia Immune Escape. Blood cancer discovery 3 (5) (2022)
Eshini Panditharatna, Joana G Marques, Tingjian Wang, Maria C Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V Dharia, Deyao Li, Samantha E Hoffman, Guillaume Kugener, McKenzie L Shaw, Hafsa M Mire, Olivia A Hack, Joshua M Dempster, Caleb A Lareau, Lingling Dai, Logan H Sigua, Michael A Quezada, Ann-Catherine J Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Frederica Piccioni, John G Doench, David E Root, Jamie N Anastas, Kristen L Jones, Amy Saur Conway, Sylwia A Stopka, Michael S Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P Jerome, Nathan D Mathewson, Sirano Dhe-Paganon, Mario L Suvà, Angel Montero Carcaboso, Cinzia Lavarino, Jaume Catala-Mora, Quang-De Nguyen, Keith L Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y R Agar, Kimberly Stegmaier, Charles D Stiles, Michelle Monje, Todd R Golub, Jun Qi, Mariella G Filbin
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma. Cancer discovery 12 (12) (2022)
Brandon J Aubrey, Jevon A Cutler, Wallace Bourgeois, Katherine A Donovan, Shengqing Gu, Charles Hatton, Sarah Perlee, Florian Perner, Homa Rahnamoun, Alexandra C P Theall, Jill A Henrich, Qian Zhu, Radosław P Nowak, Young Joon Kim, Salma Parvin, Anjali Cremer, Sarah Naomi Olsen, Nicholas A Eleuteri, Yana Pikman, Gerard M McGeehan, Kimberly Stegmaier, Anthony G Letai, Eric S Fischer, X Shirley Liu, Scott A Armstrong
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. Nature cancer 3 (5) (2022)
Bryann Pardieu, Justine Pasanisi, Frank Ling, Reinaldo Dal Bello, Justine Penneroux, Angela Su, Romane Joudinaud, Laureen Chat, Hsin Chieh Wu, Matthieu Duchmann, Gaetano Sodaro, Clémentine Chauvel, Florence A Castelli, Loic Vasseur, Kim Pacchiardi, Yannis Belloucif, Marie-Charlotte Laiguillon, Eshwar Meduri, Camille Vaganay, Gabriela Alexe, Jeannig Berrou, Chaima Benaksas, Antoine Forget, Thorsten Braun, Claude Gardin, Emmanuel Raffoux, Emmanuelle Clappier, Lionel Ades, Hugues de Thé, François Fenaille, Brian James Patrick Huntly, Kimberly Stegmaier, Hervé Dombret, Nina Fenouille, Camille Lobry, Alexandre Puissant, Raphaël A Itzykson
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia. Leukemia 36 (6) (2022)
Clare F Malone, Minjee Kim, Gabriela Alexe, Kathleen L Engel, Alexandra B Forman, Amanda L Robichaud, Amy Saur Conway, Amy Goodale, Ashleigh Meyer, Delan Khalid, Allen Thayakumar, John M Hatcher, Nathanael S Gray, Frederica Piccioni, Kimberly Stegmaier
Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors. Cancer research (2022)
Blandine Roux, Camille Vaganay, Jesse D Vargas, Gabriela Alexe, Chaima Benaksas, Bryann Pardieu, Nina Fenouille, Jana M Ellegast, Edyta Malolepsza, Frank Ling, Gaetano Sodaro, Linda Ross, Yana Pikman, Amy Saur Conway, Yangzhong Tang, Tony Wu, Daniel J Anderson, Ronan Le Moigne, Han-Jie Zhou, Frédéric Luciano, Christina R Hartigan, Ilene Galinsky, Daniel J DeAngelo, Richard M Stone, Patrick Auberger, Monica Schenone, Steven A Carr, Josée Guirouilh-Barbat, Bernard S Lopez, Mehdi Khaled, Kasper Lage, Olivier Hermine, Michael T Hemann, Alexandre Puissant, Kimberly Stegmaier, Lina Benajiba
Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. Science translational medicine 13 (587) (2021)
Yana Pikman, Nicole Ocasio-Martinez, Gabriela Alexe, Boris Dimitrov, Samuel Kitara, Frances F Diehl, Amanda L Robichaud, Amy Saur Conway, Linda Ross, Angela Su, Frank Ling, Jun Qi, Giovanni Roti, Caroline A Lewis, Alexandre Puissant, Matthew G Vander Heiden, Kimberly Stegmaier
Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy. Leukemia (2021)
Neekesh V Dharia, Guillaume Kugener, Lillian M Guenther, Clare F Malone, Adam D Durbin, Andrew L Hong, Thomas P Howard, Pratiti Bandopadhayay, Caroline S Wechsler, Iris Fung, Allison C Warren, Joshua M Dempster, John Michael Krill-Burger, Brenton R Paolella, Phoebe Moh, Nishant Jha, Andrew Tang, Phillip G Montgomery, Jesse S Boehm, William C Hahn, Charles W M Roberts, James M McFarland, Aviad Tsherniak, Todd R Golub, Francisca Vazquez, Kimberly Stegmaier
A first-generation pediatric cancer dependency map. Nature genetics 53 (4) (2021)
Nathan J Schauer, Xiaoxi Liu, Robert S Magin, Laura M Doherty, Wai Cheung Chan, Scott B Ficarro, Wanyi Hu, Rebekka M Roberts, Roxana E Iacob, Björn Stolte, Andrew O Giacomelli, Sumner Perera, Kyle McKay, Sarah A Boswell, Ellen L Weisberg, Arghya Ray, Dharminder Chauhan, Sirano Dhe-Paganon, Ken C Anderson, James D Griffin, Jianing Li, William C Hahn, Peter Karl Sorger, John R Engen, Kimberly Stegmaier, Jarrod A Marto, Sara J Buhrlage
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Scientific reports 10 (1) (2020)
Behnam Nabet, Fleur M Ferguson, Bo Kyung A Seong, Miljan Kuljanin, Alan L Leggett, Mikaela L Mohardt, Amanda Robichaud, Amy S Conway, Dennis L Buckley, Joseph D Mancias, James E Bradner, Kimberly Stegmaier, Nathanael S Gray
Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules. Nature communications 11 (1) (2020)
Adam D Durbin, Mark W Zimmerman, Neekesh V Dharia, Brian J Abraham, Amanda Balboni Iniguez, Nina Weichert-Leahey, Shuning He, John M Krill-Burger, David E Root, Francisca Vazquez, Aviad Tsherniak, William C Hahn, Todd R Golub, Richard A Young, A Thomas Look, Kimberly Stegmaier
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. Nature genetics 50 (9) (2018)
Lina Benajiba, Gabriela Alexe, Angela Su, Emmanuel Raffoux, Jean Soulier, Michael T Hemann, Olivier Hermine, Raphaël A Itzykson, Kimberly Stegmaier, Alexandre Puissant
Creatine kinase pathway inhibition alters GSK3 and WNT signaling in EVI1-positive AML. Leukemia 33 (3) (2018)
Yana Pikman, Kimberly Stegmaier
Targeted therapy for fusion-driven high-risk acute leukemia. Blood 132 (12) (2018)
Björn Stolte, Amanda Balboni Iniguez, Neekesh V Dharia, Amanda L Robichaud, Amy Saur Conway, Ann M Morgan, Gabriela Alexe, Nathan J Schauer, Xiaoxi Liu, Gregory H Bird, Aviad Tsherniak, Francisca Vazquez, Sara J Buhrlage, Loren D Walensky, Kimberly Stegmaier
Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma. The Journal of experimental medicine 215 (8) (2018)
Giovanni Roti, Jun Qi, Samuel Kitara, Marta Sanchez-Martin, Amy Saur Conway, Anthony C Varca, Angela Su, Lei Wu, Andrew L Kung, Adolfo A Ferrando, James E Bradner, Kimberly Stegmaier
Leukemia-specific delivery of mutant NOTCH1 targeted therapy. The Journal of experimental medicine 215 (1) (2017)