Jens Luebeck

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 15

Top Topics

Metastatic Colorectal Cancer

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Cancer discovery

Nature genetics

This page only lists publications with an associated author ORCID identifier.

Publications

Joseph Califano, Takuya Nakagawa, Jens Luebeck, Kaiyuan Zhu, Joshua T Lange, Roman Sasik, Chad Phillips, Sayed Sadat, Sara Javadzadeh, Qian Yang, Allen Wang, Kersi Pestonjamasp, Sara Rosenthal, Kathleen M Fisch, Paul S Mischel, Vineet Bafna
Inhibition of novel human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancer. Research square (2024)
John C Rose, Julia A Belk, Ivy Tsz-Lo Wong, Jens Luebeck, Hudson T Horn, Bence Daniel, Matthew G Jones, Kathryn E Yost, King L Hung, Kevin S Kolahi, Ellis J Curtis, Calvin J Kuo, Vineet Bafna, Paul S Mischel, Howard Y Chang
Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair. Cancer discovery (2024)
John C Rose, Julia A Belk, Ivy Tsz-Lo Wong, Jens Luebeck, Hudson T Horn, Bence Daniel, Matthew G Jones, Kathryn E Yost, King L Hung, Kevin S Kolahi, Ellis J Curtis, Calvin J Kuo, Vineet Bafna, Paul S Mischel, Howard Y Chang
Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair. Cancer discovery (2024)
Jens Luebeck, Alvin Wei Tian Ng, Patricia C Galipeau, Xiaohong Li, Carissa A Sanchez, Annalise C Katz-Summercorn, Hoon Kim, Sriganesh Jammula, Yudou He, Scott M Lippman, Roel G W Verhaak, Carlo C Maley, Ludmil B Alexandrov, Brian J Reid, Rebecca C Fitzgerald, Thomas G Paulson, Howard Y Chang, Sihan Wu, Vineet Bafna, Paul S Mischel
Extrachromosomal DNA in the cancerous transformation of Barrett's oesophagus. Nature (2023)
Davide Pradella, Minsi Zhang, Rui Gao, Melissa A Yao, Katarzyna M Gluchowska, Ylenia Cendon Florez, Tanmay Mishra, Gaspare La Rocca, Moritz Weigl, Ziqi Jiao, Hieu H M Nguyen, Felix Grimm, Marta Lisi, Chiara Mastroleo, Kevin Chen, Jens Luebeck, Vineet Bafna, Cristina R Antonescu, Andrea Ventura
Immortalization and transformation of primary cells mediated by engineered ecDNAs. bioRxiv : the preprint server for biology (2023)
Albert S Agustinus, Duaa H Al-Rawi, Bhargavi Dameracharla, Ramya Raviram, Bailey S C L Jones, Stephanie Stransky, Lorenzo Scipioni, Jens Luebeck, Melody DiBona, Danguole Norkunaite, Robert M Myers, Mercedes Duran, Seongmin Choi, Jorge S Reis-Filho, Shira Yomtoubian, Andrew McPherson, Eléonore Toufektchan, Kristina Keuper, Paul S Mischel, Vivek Mittal, Sohrab P Shah, John Maciejowski, Zuzana Storchová, Enrico Gratton, Peter Ly, Dan Landau, Mathieu F Bakhoum, Richard P Koche, Simone Sidoli, Vineet Bafna, Yael David, Samuel F Bakhoum
Epigenetic dysregulation from chromosomal transit in micronuclei. Nature (2023)
Ramya Raviram, Anugraha Raman, Sebastian Preissl, Jiangfang Ning, Shaoping Wu, Tomoyuki Koga, Kai Zhang, Cameron W Brennan, Chenxu Zhu, Jens Luebeck, Kinsey Van Deynze, Jee Yun Han, Xiaomeng Hou, Zhen Ye, Anna K Mischel, Yang Eric Li, Rongxin Fang, Tomas Baback, Joshua Mugford, Claudia Z Han, Christopher K Glass, Cathy L Barr, Paul S Mischel, Vineet Bafna, Laure Escoubet, Bing Ren, Clark C Chen
Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Ramya Raviram, Anugraha Raman, Sebastian Preissl, Jiangfang Ning, Shaoping Wu, Tomoyuki Koga, Kai Zhang, Cameron W Brennan, Chenxu Zhu, Jens Luebeck, Kinsey Van Deynze, Jee Yun Han, Xiaomeng Hou, Zhen Ye, Anna K Mischel, Yang Eric Li, Rongxin Fang, Tomas Baback, Joshua Mugford, Claudia Z Han, Christopher K Glass, Cathy L Barr, Paul S Mischel, Vineet Bafna, Laure Escoubet, Bing Ren, Clark C Chen
Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Ramya Raviram, Anugraha Raman, Sebastian Preissl, Jiangfang Ning, Shaoping Wu, Tomoyuki Koga, Kai Zhang, Cameron W Brennan, Chenxu Zhu, Jens Luebeck, Kinsey Van Deynze, Jee Yun Han, Xiaomeng Hou, Zhen Ye, Anna K Mischel, Yang Eric Li, Rongxin Fang, Tomas Baback, Joshua Mugford, Claudia Z Han, Christopher K Glass, Cathy L Barr, Paul S Mischel, Vineet Bafna, Laure Escoubet, Bing Ren, Clark C Chen
Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Ramya Raviram, Anugraha Raman, Sebastian Preissl, Jiangfang Ning, Shaoping Wu, Tomoyuki Koga, Kai Zhang, Cameron W Brennan, Chenxu Zhu, Jens Luebeck, Kinsey Van Deynze, Jee Yun Han, Xiaomeng Hou, Zhen Ye, Anna K Mischel, Yang Eric Li, Rongxin Fang, Tomas Baback, Joshua Mugford, Claudia Z Han, Christopher K Glass, Cathy L Barr, Paul S Mischel, Vineet Bafna, Laure Escoubet, Bing Ren, Clark C Chen
Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Kai Song, Jenna K Minami, Arthur Huang, Siavash R Dehkordi, Shirley H Lomeli, Jens Luebeck, Mark H Goodman, Gatien Moriceau, Oscar Krijgsman, Prashanthi Dharanipragada, Trevor Ridgley, William P Crosson, Jesus Salazar, Eli Pazol, Gabriel Karin, Rachana Jayaraman, Nikolas G Balanis, Salwan Alhani, Kyle Sheu, Johanna Ten Hoeve, Amelia Palermo, Stephen E Motika, T Niroshi Senaratne, Kim H Paraiso, Paul J Hergenrother, P Nagesh Rao, Asha S Multani, Daniel S Peeper, Vineet Bafna, Roger S Lo, Thomas Glen Graeber
Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges. Cancer discovery 12 (4) (2022)
King L Hung, Jens Luebeck, Siavash R Dehkordi, Caterina I Colón, Rui Li, Ivy Tsz-Lo Wong, Ceyda Coruh, Prashanthi Dharanipragada, Shirley H Lomeli, Natasha E Weiser, Gatien Moriceau, Xiao Zhang, Chris Bailey, Kathleen E Houlahan, Wenting Yang, Rocio Chamorro González, Charles Swanton, Christina Curtis, Mariam Jamal-Hanjani, Anton G Henssen, Julie A Law, William J Greenleaf, Roger S Lo, Paul S Mischel, Vineet Bafna, Howard Y Chang
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH. Nature genetics 54 (11) (2022)
John Pang, Nam-Phuong Nguyen, Jens Luebeck, Laurel Ball, Andrey Finegersh, Shuling Ren, Takuya Nakagawa, Mitchell Flagg, Sayed Sadat, Paul S Mischel, Guorong Xu, Kathleen M Fisch, Theresa W Guo, Gabrielle Cahill, Bharat Panuganti, Vineet Bafna, Joseph Califano
Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
King L Hung, Kathryn E Yost, Liangqi Xie, Quanming Shi, Konstantin Helmsauer, Jens Luebeck, Robert Schöpflin, Joshua T Lange, Rocio Chamorro González, Natasha E Weiser, Celine Y Chen, Maria E Stefanova, Ivy Tsz-Lo Wong, Sihan Wu, Siavash R Dehkordi, Connor V Duffy, Katerina Kraft, Jun Tang, Julia A Belk, John C Rose, M Ryan Corces, Jeffrey M Granja, Rui Li, Utkrisht Rajkumar, Jordan Friedlein, Anindya Bagchi, Ansuman T Satpathy, Robert Tjian, Stefan Mundlos, Vineet Bafna, Anton G Henssen, Paul S Mischel, Zhe J Liu, Howard Y Chang
ecDNA hubs drive cooperative intermolecular oncogene expression. Nature (2021)
Hoon Kim, Nam-Phuong Nguyen, Kristen Turner, Sihan Wu, Amit D Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi, Samirkumar B Amin, Eunhee Yi, Francesca Menghi, Johannes H Schulte, Anton G Henssen, Howard Y Chang, Christine R Beck, Paul S Mischel, Vineet Bafna, Roel G W Verhaak
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers. Nature genetics 52 (9) (2020)