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John E Dick (John Dick)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 27

Top Venues

Blood cancer discovery

Nature communications

Blood

Cancer discovery

University Health Network

University of Manitoba Manitoba Institute of Cell Biology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University Health Network Dec 7o 2018

Canada

Affiliate Faculty Member, McEwen Stem Cell Institute

Education History

University of Manitoba Manitoba Institute of Cell Biology

Canada

PHD

Publications

Ana Vujovic, Laura P M H de Rooij, Ava Keyvani Chahi, He Tian Tony Chen, Brian A Yee, Sampath Kumar Loganathan, Lina Liu, Derek C H Chan, Amanda Tajik, Emily Tsao, Steven Moreira, Pratik Joshi, Joshua Xu, Nicholas Wong, Zaldy Balde, Soheil Jahangiri, Sasan Zandi, Stefan Aigner, John E Dick, Mark D Minden, Daniel Schramek, Gene W Yeo, Kristin J Hope
In vivo screening unveils pervasive RNA-binding protein dependencies in leukemic stem cells and identifies ELAVL1 as a therapeutic target. Blood cancer discovery (2023)
Winnie L Kan, Urmi Dhagat, Kerstin B Kaufmann, Timothy R Hercus, Tracy L Nero, Andy Gx Zeng, John Toubia, Emma F Barry, Sophie E Broughton, Guillermo A Gomez, Brooks A Benard, Mara Dottore, Karen S Cheung Tung Shing, Helena Boutzen, Saumya E Samaraweera, Kaylene J Simpson, Liqing Jin, Gregory J Goodall, C Glenn Begley, Daniel Thomas, Paul G Ekert, Denis Tvorogov, Richard J D'Andrea, John E Dick, Michael W Parker, Angel F Lopez
Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia. Cancer discovery (2023)
Ana Vujovic, Laura P M H de Rooij, Ava Keyvani Chahi, He Tian Tony Chen, Brian A Yee, Sampath Kumar Loganathan, Lina Liu, Derek C H Chan, Amanda Tajik, Emily Tsao, Steven Moreira, Pratik Joshi, Joshua Xu, Nicholas Wong, Zaldy Balde, Soheil Jahangiri, Sasan Zandi, Stefan Aigner, John E Dick, Mark D Minden, Daniel Schramek, Gene W Yeo, Kristin J Hope
In vivo screening unveils pervasive RNA-binding protein dependencies in leukemic stem cells and identifies ELAVL1 as a therapeutic target. Blood cancer discovery (2023)
Jeff A Wintersinger, Stephanie M Dobson, Ethan Kulman, Lincoln D Stein, John E Dick, Quaid Morris
Reconstructing Complex Cancer Evolutionary Histories from Multiple Bulk DNA Samples Using Pairtree. Blood cancer discovery 3 (3) (2022)
Andy G X Zeng, Suraj Bansal, Liqing Jin, Amanda Mitchell, Weihsu Claire Chen, Hussein A Abbas, Michelle Chan-Seng-Yue, Veronique Voisin, Peter van Galen, Anne Tierens, Meyling H Cheok, Claude Preudhomme, Hervé Dombret, Naval Daver, P Andrew Futreal, Mark D Minden, James A Kennedy, Jean C Y Wang, John E Dick
A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia. Nature medicine 28 (6) (2022)
Fernando Luís Scolari, Sagi Abelson, Darshan H Brahmbhatt, Jessie J F Medeiros, Chun-Po Steve Fan, Nicole L Fung, Vesna Mihajlovic, Markus S Anker, Madison Otsuki, Patrick R Lawler, Heather Joan Ross, Adriana C Luk, Stefan D Anker, John E Dick, Filio Billia
Clonal haematopoiesis is associated with higher mortality in patients with cardiogenic shock. European journal of heart failure 24 (9) (2022)
Héléna Boutzen, Seyed Ali Madani Tonekaboni, Michelle Chan-Seng-Yue, Alex Murison, Naoya Takayama, Nathan Mbong, Elvin Wagenblast, Elias Orouji, Andrea Arruda, Amanda Mitchell, Faiyaz Notta, Mark D Minden, Mathieu Lupien, Kerstin B Kaufmann, John E Dick
A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome. Leukemia 36 (11) (2022)
Ava Keyvani Chahi, Muluken S Belew, Joshua Xu, He Tian Tony Chen, Stefan Rentas, Veronique Voisin, Gabriela Krivdova, Eric R Lechman, Sajid A Marhon, Daniel D De Carvalho, John E Dick, Gary D Baider, Kristin J Hope
PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal. Blood 140 (9) (2022)
Fernando Luís Scolari, Darshan H Brahmbhatt, Sagi Abelson, Jessie J F Medeiros, Markus S Anker, Nicole L Fung, Madison Otsuki, Oscar Calvillo-Argüelles, Patrick R Lawler, Heather Joan Ross, Adriana C Luk, Stefan D Anker, John E Dick, Filio Billia
Clonal hematopoiesis confers an increased mortality risk in orthotopic heart transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 22 (12) (2022)
Esmé Waanders, Zhaohui Gu, Stephanie M Dobson, Željko Antić, Jeremy Chase Crawford, Xiaotu Ma, Michael N Edmonson, Debbie Payne-Turner, Maartje van de Vorst, Marjolijn C J Jongmans, Irina McGuire, Xin Zhou, Jian Wang, Lei Shi, Stanley Pounds, Deqing Pei, Cheng Cheng, Guangchun Song, Yiping Fan, Ying Shao, Michael C Rusch, Kelly McCastlain, Jiangyan Yu, Ruben van Boxtel, Francis Blokzijl, Ilaria Iacobucci, Kathryn G Roberts, Ji Wen, Gang Wu, Jing Ma, John Easton, Geoffrey A Neale, Scott R Olsen, Kim E Nichols, Ching-Hon Pui, Jinghui Zhang, William E Evans, Mary V Relling, Jun J Yang, Paul Glyndwr Thomas, John E Dick, Roland P Kuiper, Charles G Mullighan
Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia. Blood cancer discovery 1 (1) (2022)
James L C Che, Daniel Bode, Iwo Kucinski, Alyssa H Cull, Fiona Bain, Hans J Becker, Maria Jassinskaja, Melania Barile, Grace Boyd, Miriam Belmonte, Andy G X Zeng, Kyomi J Igarashi, Juan Rubio-Lara, Mairi S Shepherd, Anna Clay, John E Dick, Adam C Wilkinson, Hiromitsu Nakauchi, Satoshi Yamazaki, Berthold Göttgens, David G Kent
Identification and characterization of in vitro expanded hematopoietic stem cells. EMBO reports 23 (10) (2022)
Kimberly Skead, Armande Ang Houle, Sagi Abelson, Mawusse Agbessi, Vanessa Bruat, Boxi Lin, David Soave, Liran Shlush, Stephen I Wright, John E Dick, Quaid D Morris, Philip Awadalla
Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood. Nature communications 12 (1) (2021)
Robert J Vanner, Stephanie M Dobson, Olga I Gan, Jessica McLeod, Erwin M Schoof, Ildiko Grandal, Jeff A Wintersinger, Laura Garcia-Prat, Mohsen Hosseini, Stephanie Z Xie, Liqing Jin, Nathan Mbong, Veronique Voisin, Michelle Chan-Seng-Yue, James A Kennedy, Esmé Waanders, Quaid Morris, Bo Torben Porse, Steven M Chan, Cynthia J Guidos, Jayne S Danska, Mark D Minden, Charles G Mullighan, John E Dick
Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target. Blood cancer discovery 3 (1) (2021)
Arvind Singh Mer, Emily M Heath, Seyed Ali Madani Tonekaboni, Nergiz Dogan-Artun, Sisira Kadambat Nair, Alex Murison, Laura Garcia-Prat, Liran I Shlush, Rose Hurren, Veronique Voisin, Gary D Baider, Corey Nislow, Mattias Rantalainen, Soren Lehmann, Mark Gower, Cynthia J Guidos, Mathieu Lupien, John E Dick, Mark D Minden, Aaron David Schimmer, Benjamin Haibe-Kains
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML. Nature communications 12 (1) (2021)
Erwin M Schoof, Benjamin Furtwängler, Nil Üresin, Nicolas Rapin, Simonas Savickas, Coline Gentil, Eric R Lechman, Ulrich Auf dem Keller, John E Dick, Bo Torben Porse
Quantitative single-cell proteomics as a tool to characterize cellular hierarchies. Nature communications 12 (1) (2021)
Kerstin B Kaufmann, Andy G X Zeng, Etienne Coyaud, Laura Garcia-Prat, Efthymia Papalexi, Alex Murison, Estelle M N Laurent, Michelle Chan-Seng-Yue, Olga I Gan, Kristele Pan, Jessica McLeod, Héléna Boutzen, Sasan Zandi, Shin-Ichiro Takayanagi, Rahul Satija, Brian Raught, Stephanie Z Xie, John E Dick
A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness. Nature immunology 22 (6) (2021)
Elvin Wagenblast, Joana Araújo, Olga I Gan, Sarah K Cutting, Alex Murison, Gabriela Krivdova, Maria Azkanaz, Jessica L McLeod, Sabrina A Smith, Blaise A Gratton, Sajid A Marhon, Martino Gabra, Jessie J F Medeiros, Sanaz Manteghi, Jian Chen, Michelle Chan-Seng-Yue, Laura Garcia-Prat, Leonardo Salmena, Daniel D De Carvalho, Sagi Abelson, Mohamed Abdelhaleem, Karen Chong, Maian Roifman, Patrick Shannon, Jean C Y Wang, Johann K Hitzler, David Chitayat, John E Dick, Eric R Lechman
Mapping the cellular origin and early evolution of leukemia in Down syndrome. Science (New York, N.Y.) 373 (6551) (2021)
Lindsey E Montefiori, Sonja Bendig, Zhaohui Gu, Xiaolong Chen, Petri Pölönen, Xiaotu Ma, Alex Murison, Andy Zeng, Laura Garcia-Prat, Kirsten Dickerson, Ilaria Iacobucci, Sherif Abdelhamed, Ryan Hiltenbrand, Paul E Mead, Cyrus M Mehr, Bei-Si Xu, Zhongshan Cheng, Ti-Cheng Chang, Tamara Westover, Jing Ma, Anna Stengel, Shunsuke Kimura, Chunxu Qu, Marcus B Valentine, Marissa Rashkovan, Selina Luger, Mark R Litzow, Jacob M Rowe, Monique L Den Boer, Victoria Wang, Jun Yin, Steven M Kornblau, Stephen P Hunger, Mignon L Loh, Ching-Hong Pui, Wenjian Yang, Kristine R Crews, Kathryn G Roberts, Jun J Yang, Mary V Relling, William E Evans, Wendy Stock, Elisabeth M Paietta, Adolfo A Ferrando, Jinghui Zhang, Wolfgang Kern, Torsten Haferlach, Gang Wu, John E Dick, Jeffery M Klco, Claudia Haferlach, Charles G Mullighan
Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia. Cancer discovery 11 (11) (2021)
Stanley Wk Ng, Tracy Murphy, Ian King, Tong Zhang, Michelle Mah, Zhibin Lu, Natalie Stickle, Narmin Ibrahimova, Andrea Arruda, Amanda Mitchell, Ming Mai, Rong He, Bindu Swapna Madala, David S Viswanatha, John E Dick, Steven Mc Chan, Carl Virtanen, Mark D Minden, Timothy R Mercer, Tracy L Stockley, Jean C Y Wang
A Clinical Laboratory-Developed LSC17 Stemness Score Assay for Rapid Risk Assessment of Acute Myeloid Leukemia Patients. Blood advances (2021)
Sagi Abelson, Andy G X Zeng, Ido Nofech-Mozes, Ting Ting Wang, Stanley W K Ng, Mark D Minden, Trevor J Pugh, Philip Awadalla, Liran I Shlush, Tracy Murphy, Steven M Chan, John E Dick, Scott V Bratman
Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing. Science advances 6 (50) (2020)
Stephanie M Dobson, Laura García-Prat, Robert J Vanner, Jeffrey Wintersinger, Esmé Waanders, Zhaohui Gu, Jessica McLeod, Olga I Gan, Ildiko Grandal, Debbie Payne-Turner, Michael N Edmonson, Xiaotu Ma, Yiping Fan, Veronique Voisin, Michelle Chan-Seng-Yue, Stephanie Z Xie, Mohsen Hosseini, Sagi Abelson, Pankaj Gupta, Michael C Rusch, Ying Shao, Scott R Olsen, Geoffrey A Neale, Steven M Chan, Gary D Baider, John Easton, Cynthia J Guidos, Jayne S Danska, Jinghui Zhang, Mark D Minden, Quaid Morris, Charles G Mullighan, John E Dick
Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs. Cancer discovery 10 (4) (2020)
Nasma Aqaqe, Muhammad Yassin, Abed Alkader Yassin, Nour Ershaid, Chen Katz-Even, Adi Zipin-Roitman, Eitan Kugler, Eric R Lechman, Olga I Gan, Amanda Mitchell, John E Dick, Shai Izraeli, Michael Milyavsky
An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation. Cancer research 79 (15) (2019)
Elvin Wagenblast, Maria Azkanaz, Sabrina A Smith, Lorien Shakib, Jessica L McLeod, Gabriela Krivdova, Joana Araújo, Leonard D Shultz, Olga I Gan, John E Dick, Eric R Lechman
Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells. Nature communications 10 (1) (2019)
Kerstin B Kaufmann, Laura Garcia-Prat, Qiang Liu, Stanley W K Ng, Shin-Ichiro Takayanagi, Amanda Mitchell, Erno Wienholds, Peter van Galen, Christian A Cumbaa, Mike J Tsay, Chiara Pastrello, Elvin Wagenblast, Gabriela Krivdova, Mark D Minden, Eric R Lechman, Sasan Zandi, Igor Jurisica, Jean C Y Wang, Stephanie Z Xie, John E Dick
A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency. Blood 133 (20) (2019)
Nicolas Duployez, Alice Marceau-Renaut, Céline Villenet, Arnaud Petit, Alexandra Rousseau, Stanley W K Ng, Agnès Paquet, Fanny Gonzales, Adeline Barthélémy, Frédéric Leprêtre, Nicolas Pottier, Brigitte Nelken, Gérard Michel, André Baruchel, Yves Bertrand, Guy Leverger, Hélène Lapillonne, Martin Figeac, John E Dick, Jean C Y Wang, Claude Preudhomme, Meyling H Cheok
The stem cell-associated gene expression signature allows risk stratification in pediatric acute myeloid leukemia. Leukemia 33 (2) (2018)
James A Kennedy, Jessie J F Medeiros, Stephanie M Dobson, Andrea Arruda, Mahadeo A Sukhai, Tracy Stockley, Anne Tierens, Mark D Minden, Suzanne Kamel-Reid, John E Dick, Vikas Gupta
Distinct patterns of clonal evolution in patients with concurrent myelo- and lymphoproliferative neoplasms. Blood 132 (20) (2018)
Jinghui Zhang, Kelly McCastlain, Hiroki Yoshihara, Bei-Si Xu, Yunchao Chang, Michelle L Churchman, Gang Wu, Yongjin Li, Lei Wei, Ilaria Iacobucci, Yu Liu, Chunxu Qu, Ji Wen, Michael Edmonson, Debbie Payne-Turner, Kerstin B Kaufmann, Shin-Ichiro Takayanagi, Erno Wienholds, Esmé Waanders, Panagiotis Ntziachristos, Sofia Bakogianni, Jingjing Wang, Iannis Aifantis, Kathryn G Roberts, Jing Ma, Guangchun Song, John Easton, Heather L Mulder, Xiang Chen, Scott Newman, Xiaotu Ma, Michael C Rusch, Pankaj Gupta, Kristy Boggs, Bhavin Vadodaria, James Dalton, Yanling Liu, Marcus L Valentine, Li Ding, Charles Lu, Robert S Fulton, Lucinda Fulton, Yashodhan Tabib, Kerri Ochoa, Meenakshi Devidas, Deqing Pei, Cheng Cheng, Jun J Yang, William E Evans, Mary V Relling, Ching-Hon Pui, Sima Jeha, Richard C Harvey, I-Ming L Chen, Cheryl L Willman, Guido Marcucci, Clara D Bloomfield, Jessica Kohlschmidt, Krzysztof Mrózek, Elisabeth Paietta, Martin S Tallman, Wendy Stock, Matthew C Foster, Janis Racevskis, Jacob M Rowe, Selina Luger, Steven M Kornblau, Sheila A Shurtleff, Susana C Raimondi, Elaine R Mardis, Richard K Wilson, John E Dick, Stephen P Hunger, Mignon L Loh, James R Downing, Charles G Mullighan, null null
Deregulation of DUX4 and ERG in acute lymphoblastic leukemia. Nature genetics 48 (12) (2016)

John E Dick.css-eqlu8i{font-size:small;padding-left:4px;} (John Dick)

Publication Activity (10 Years)

Top Topics

Top Venues

John E Dick (John Dick)