Michael D Burkart

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 67

Top Venues

Journal of the American Chemical Society

Journal of medicinal chemistry

ACS chemical biology

Biochemistry

University of California San Diego

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California San Diego

United States

Professor :: Chemistry and Biochemistry

Publications

Matthew G Miyada, Yuran Choi, Ramunas Stepanauskas, Tanja Woyke, James J La Clair, Michael D Burkart
Fluorometric Analysis of Carrier-Protein-Dependent Biosynthesis through a Conformationally Sensitive Solvatochromic Pantetheinamide Probe. ACS chemical biology (2024)
Aochiu Chen, Rebecca N Re, Tony D Davis, Kelley Tran, Yuta W Moriuchi, Sitong Wu, James J La Clair, Gordon V Louie, Marianne E Bowman, David James Clark, C L Logan Mackay, Dominic J Campopiano, Joseph A P Noel, Michael D Burkart
Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes. Journal of the American Chemical Society 146 (2) (2024)
Matthew G Miyada, Yuran Choi, Ramunas Stepanauskas, Tanja Woyke, James J La Clair, Michael D Burkart
Fluorometric Analysis of Carrier-Protein-Dependent Biosynthesis through a Conformationally Sensitive Solvatochromic Pantetheinamide Probe. ACS chemical biology 19 (7) (2024)
Aochiu Chen, Rebecca N Re, Tony D Davis, Kelley Tran, Yuta W Moriuchi, Sitong Wu, James J La Clair, Gordon V Louie, Marianne E Bowman, David James Clark, C L Logan Mackay, Dominic J Campopiano, Joseph A P Noel, Michael D Burkart
Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes. Journal of the American Chemical Society 146 (2) (2024)
Brianna N Kalaj, James J La Clair, Yang Shen, Charles D Schwieters, Lalit Deshmukh, Michael D Burkart
Quantitative Characterization of Chain-Flipping of Acyl Carrier Protein of Escherichia coli Using Chemical Exchange NMR. Journal of the American Chemical Society (2024)
Brianna N Kalaj, James J La Clair, Yang Shen, Charles D Schwieters, Lalit Deshmukh, Michael D Burkart
Quantitative Characterization of Chain-Flipping of Acyl Carrier Protein of Escherichia coli Using Chemical Exchange NMR. Journal of the American Chemical Society 146 (27) (2024)
Aochiu Chen, Rebecca N Re, Tony D Davis, Kelley Tran, Yuta W Moriuchi, Sitong Wu, James J La Clair, Gordon V Louie, Marianne E Bowman, David James Clark, C L Logan Mackay, Dominic J Campopiano, Joseph A P Noel, Michael D Burkart
Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes. Journal of the American Chemical Society (2024)
Aochiu Chen, Rebecca N Re, Tony D Davis, Kelley Tran, Yuta W Moriuchi, Sitong Wu, James J La Clair, Gordon V Louie, Marianne E Bowman, David James Clark, C L Logan Mackay, Dominic J Campopiano, Joseph A P Noel, Michael D Burkart
Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes. Journal of the American Chemical Society 146 (2) (2024)
Brianna N Kalaj, James J La Clair, Yang Shen, Charles D Schwieters, Lalit Deshmukh, Michael D Burkart
Quantitative Characterization of Chain-Flipping of Acyl Carrier Protein of Escherichia coli Using Chemical Exchange NMR. Journal of the American Chemical Society (2024)
Brianna N Kalaj, James J La Clair, Yang Shen, Charles D Schwieters, Lalit Deshmukh, Michael D Burkart
Quantitative Characterization of Chain-Flipping of Acyl Carrier Protein of Escherichia coli Using Chemical Exchange NMR. Journal of the American Chemical Society (2024)
Ziran Jiang, Jeffrey A Chen, Osama G Mohamed, Jennifer Huynh, Aochiu Chen, Ashootosh Tripathi, James J La Clair, Michael D Burkart
Cryptic Cerulenin Rearrangement in Ketosynthase Covalent Inhibition. Journal of the American Chemical Society (2024)
Brianna N Kalaj, James J La Clair, Yang Shen, Charles D Schwieters, Lalit Deshmukh, Michael D Burkart
Quantitative Characterization of Chain-Flipping of Acyl Carrier Protein of Escherichia coli Using Chemical Exchange NMR. Journal of the American Chemical Society 146 (27) (2024)
Ziran Jiang, Jeffrey A Chen, Osama G Mohamed, Jennifer Huynh, Aochiu Chen, Ashootosh Tripathi, James J La Clair, Michael D Burkart
Cryptic Cerulenin Rearrangement in Ketosynthase Covalent Inhibition. Journal of the American Chemical Society 146 (29) (2024)
Patrick D Fischer, Abu Sayeed Chowdhury, Thomas Bartholow, Shibani Basu, Eric Baggs, Huel S Cox, Srđan Matošin, Michael D Burkart, Lisa Warner, Rajesh Nagarajan, Haribabu Arthanari
Carrier protein mediated cargo sensing in quorum signal synthases. Chemical communications (Cambridge, England) (2023)
Patrick D Fischer, Abu Sayeed Chowdhury, Thomas Bartholow, Shibani Basu, Eric Baggs, Huel S Cox, Srđan Matošin, Michael D Burkart, Lisa Warner, Rajesh Nagarajan, Haribabu Arthanari
Carrier protein mediated cargo sensing in quorum signal synthases. Chemical communications (Cambridge, England) 59 (8) (2023)
Warren C Chan, Kelsey A Trieger, James J La Clair, Catriona H M Jamieson, Michael D Burkart
Stereochemical Control of Splice Modulation in FD-895 Analogues. Journal of medicinal chemistry (2023)
Terra Sztain, Joshua C Corpuz, Thomas G Bartholow, Javier O Sanlley Hernandez, Ziran Jiang, Desirae A Mellor, Graham W Heberlig, James J La Clair, James Andrew McCammon, Michael D Burkart
Interface Engineering of Carrier-Protein-Dependent Metabolic Pathways. ACS chemical biology (2023)
Conor B O'Herin, Yuta W Moriuchi, Troy A Bemis, Alysia J Kohlbrand, Michael D Burkart, Seth M Cohen
Development of Human Carbonic Anhydrase II Heterobifunctional Degraders. Journal of medicinal chemistry 66 (4) (2023)
Patrick D Fischer, Abu Sayeed Chowdhury, Thomas Bartholow, Shibani Basu, Eric Baggs, Huel S Cox, Srđan Matošin, Michael D Burkart, Lisa Warner, Rajesh Nagarajan, Haribabu Arthanari
Carrier protein mediated cargo sensing in quorum signal synthases. Chemical communications (Cambridge, England) 59 (8) (2023)
Ziran Jiang, Aochiu Chen, Jeffrey Chen, Arman Sekhon, Gordon V Louie, Joseph A P Noel, James J La Clair, Michael D Burkart
Masked cerulenin enables a dual-site selective protein crosslink. Chemical science 14 (39) (2023)
Patrick D Fischer, Abu Sayeed Chowdhury, Thomas Bartholow, Shibani Basu, Eric Baggs, Huel S Cox, Srđan Matošin, Michael D Burkart, Lisa Warner, Rajesh Nagarajan, Haribabu Arthanari
Carrier protein mediated cargo sensing in quorum signal synthases. Chemical communications (Cambridge, England) 59 (8) (2023)
Conor B O'Herin, Yuta W Moriuchi, Troy A Bemis, Alysia J Kohlbrand, Michael D Burkart, Seth M Cohen
Development of Human Carbonic Anhydrase II Heterobifunctional Degraders. Journal of medicinal chemistry (2023)
Conor B O'Herin, Yuta W Moriuchi, Troy A Bemis, Alysia J Kohlbrand, Michael D Burkart, Seth M Cohen
Development of Human Carbonic Anhydrase II Heterobifunctional Degraders. Journal of medicinal chemistry 66 (4) (2023)
Conor B O'Herin, Yuta W Moriuchi, Troy A Bemis, Alysia J Kohlbrand, Michael D Burkart, Seth M Cohen
Development of Human Carbonic Anhydrase II Heterobifunctional Degraders. Journal of medicinal chemistry 66 (4) (2023)
Conor B O'Herin, Yuta W Moriuchi, Troy A Bemis, Alysia J Kohlbrand, Michael D Burkart, Seth M Cohen
Development of Human Carbonic Anhydrase II Heterobifunctional Degraders. Journal of medicinal chemistry 66 (4) (2023)
Wei Cao, Haochuan Mao, Naneki C McCallum, Xuhao Zhou, Hao Sun, Christopher Sharpe, Joanna Korpanty, Ziying Hu, Qing Zhe Ni, Michael D Burkart, Matthew D Shawkey, Michael R Wasielewski, Nathan C Gianneschi
Biomimetic pheomelanin to unravel the electronic, molecular and supramolecular structure of the natural product. Chemical science 14 (15) (2023)
Patrick D Fischer, Abu Sayeed Chowdhury, Thomas Bartholow, Shibani Basu, Eric Baggs, Huel S Cox, Srđan Matošin, Michael D Burkart, Lisa Warner, Rajesh Nagarajan, Haribabu Arthanari
Carrier protein mediated cargo sensing in quorum signal synthases. Chemical communications (Cambridge, England) 59 (8) (2023)
Woojoo E Kim, Fumihiro Ishikawa, Rebecca N Re, Takehiro Suzuki, Naoshi Dohmae, Hideaki Kakeya, Genzoh Tanabe, Michael D Burkart
Developing crosslinkers specific for epimerization domain in NRPS initiation modules to evaluate mechanism. RSC chemical biology 3 (3) (2022)
Thien An Phung Hai, Anton A Samoylov, Bhausaheb S Rajput, Michael D Burkart
Laboratory Ozonolysis Using an Integrated Batch-DIY Flow System for Renewable Material Production. ACS omega 7 (18) (2022)
Aochiu Chen, Jeffrey T Mindrebo, Tony D Davis, Woojoo E Kim, Yohei Katsuyama, Ziran Jiang, Yasuo Ohnishi, Joseph A P Noel, Michael D Burkart
Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states. Acta crystallographica. Section D, Structural biology 78 (Pt 9) (2022)
Bhausaheb S Rajput, Thien An Phung Hai, Michael D Burkart
High Bio-Content Thermoplastic Polyurethanes from Azelaic Acid. Molecules (Basel, Switzerland) 27 (15) (2022)
Thomas G Bartholow, Terra Sztain, Megan A Young, D John Lee, Tony D Davis, Ruben Abagyan, Michael D Burkart
Control of Unsaturation in De Novo Fatty Acid Biosynthesis by FabA. Biochemistry 61 (7) (2022)
Aochiu Chen, Ziran Jiang, Michael D Burkart
Enzymology of standalone elongating ketosynthases. Chemical science 13 (15) (2022)
Brianna N Kalaj, Qing Zhe Ni, James J La Clair, Dimitri D Deheyn, Michael D Burkart
Chemoenzymatic Isolation and Characterization of High Purity Mammalian Melanin. Chembiochem : a European journal of chemical biology 23 (9) (2022)
Joshua C Corpuz, Ashay Patel, Tony D Davis, Larissa M Podust, James Andrew McCammon, Michael D Burkart
Essential Role of Loop Dynamics in Type II NRPS Biomolecular Recognition. ACS chemical biology 17 (10) (2022)
Saranshu Singla, K Zin Htut, Runyao Zhu, Amara Davis, Jiayang Ma, Qing Zhe Ni, Michael D Burkart, Christopher Maurer, Toshikazu Miyoshi, Ali Dhinojwala
Isolation and Characterization of Allomelanin from Pathogenic Black Knot Fungus-a Sustainable Source of Melanin. ACS omega 6 (51) (2021)
Wei Cao, Xuhao Zhou, Naneki C McCallum, Ziying Hu, Qing Zhe Ni, Utkarsh Kapoor, Christian M Heil, Kristine S Cay, Tara Zand, Alex J Mantanona, Arthi Jayaraman, Ali Dhinojwala, Dimitri D Deheyn, Matthew D Shawkey, Michael D Burkart, Jeffrey D Rinehart, Nathan C Gianneschi
Unraveling the Structure and Function of Melanin through Synthesis. Journal of the American Chemical Society 143 (7) (2021)
Thien An Phung Hai, Marissa Tessman, Nitin Neelakantan, Anton A Samoylov, Yuri Ito, Bhausaheb S Rajput, Naser Pourahmady, Michael D Burkart
Renewable Polyurethanes from Sustainable Biological Precursors. Biomacromolecules 22 (5) (2021)
Satyam Khanal, Roberto J Brea, Michael D Burkart, Neal K Devaraj
Chemoenzymatic Generation of Phospholipid Membranes Mediated by Type I Fatty Acid Synthase. Journal of the American Chemical Society 143 (23) (2021)
Thomas G Bartholow, Terra Sztain, Ashay Patel, D John Lee, Megan A Young, Ruben Abagyan, Michael D Burkart
Elucidation of transient protein-protein interactions within carrier protein-dependent biosynthesis. Communications biology 4 (1) (2021)
Jeffrey T Mindrebo, Aochiu Chen, Woojoo E Kim, Rebecca N Re, Tony D Davis, Joseph A P Noel, Michael D Burkart
Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases. ACS catalysis 11 (12) (2021)
Thomas G Bartholow, Terra Sztain, Megan A Young, Tony D Davis, Ruben Abagyan, Michael D Burkart
Protein-protein interaction based substrate control in the E. coli octanoic acid transferase, LipB. RSC chemical biology 2 (5) (2021)
Woojoo E Kim, Katherine Charov, Mária Džunková, Eric D Becraft, Julia Brown, Frederik Schulz, Tanja Woyke, James J La Clair, Ramunas Stepanauskas, Michael D Burkart
Synthase-Selective Exploration of a Tunicate Microbiome by Activity-Guided Single-Cell Genomics. ACS chemical biology 16 (5) (2021)
Terra Sztain, Thomas G Bartholow, D John Lee, Lorenzo Casalino, Andrew Mitchell, Megan A Young, Jianing Wang, James Andrew McCammon, Michael D Burkart
Decoding allosteric regulation by the acyl carrier protein. Proceedings of the National Academy of Sciences of the United States of America 118 (16) (2021)
Matt J Jaremko, Tony D Davis, Joshua C Corpuz, Michael D Burkart
Type II non-ribosomal peptide synthetase proteins: structure, mechanism, and protein-protein interactions. Natural product reports 37 (3) (2021)
Troy A Bemis, James J La Clair, Michael D Burkart
Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras. Journal of medicinal chemistry 64 (12) (2021)
Jeffrey T Mindrebo, Laetitia E Misson, Caitlin Johnson, Joseph A P Noel, Michael D Burkart
Activity Mapping the Acyl Carrier Protein: Elongating Ketosynthase Interaction in Fatty Acid Biosynthesis. Biochemistry 59 (38) (2020)
Wei Cao, Naneki C McCallum, Qing Zhe Ni, Weiyao Li, Hannah Boyce, Haochuan Mao, Xuhao Zhou, Hao Sun, Matthew P Thompson, Claudia Battistella, Michael R Wasielewski, Ali Dhinojwala, Matthew D Shawkey, Michael D Burkart, Zheng Wang, Nathan C Gianneschi
Selenomelanin: An Abiotic Selenium Analogue of Pheomelanin. Journal of the American Chemical Society 142 (29) (2020)
Kelsey A Trieger, James J La Clair, Michael D Burkart
Splice Modulation Synergizes Cell Cycle Inhibition. ACS chemical biology 15 (3) (2020)
Qing Zhe Ni, Brianna N Kalaj, James J La Clair, Michael D Burkart
Chemoenzymatic elaboration of the Raper-Mason pathway unravels the structural diversity within eumelanin pigments. Chemical science 11 (30) (2020)
Danyao Du, Yohei Katsuyama, Masanobu Horiuchi, Shinya Fushinobu, Aochiu Chen, Tony D Davis, Michael D Burkart, Yasuo Ohnishi
Structural basis for selectivity in a highly reducing type II polyketide synthase. Nature chemical biology 16 (7) (2020)
Rohit H Subramanian, Yuta Suzuki, Lorillee Tallorin, Swagat Sahu, Matthew Thompson, Nathan C Gianneschi, Michael D Burkart, F Akif Tezcan
Enzyme-Directed Functionalization of Designed, Two-Dimensional Protein Lattices. Biochemistry 60 (13) (2020)
Laetitia E Misson, Jeffrey T Mindrebo, Tony D Davis, Ashay Patel, James Andrew McCammon, Joseph P Noel, Michael D Burkart
Interfacial plasticity facilitates high reaction rate of E. coli FAS malonyl-CoA:ACP transacylase, FabD. Proceedings of the National Academy of Sciences of the United States of America 117 (39) (2020)
Jeffrey T Mindrebo, Ashay Patel, Woojoo E Kim, Tony D Davis, Aochiu Chen, Thomas G Bartholow, James J La Clair, J Andrew McCammon, Joseph A P Noel, Michael D Burkart
Gating mechanism of elongating β-ketoacyl-ACP synthases. Nature communications 11 (1) (2020)
Jacob C Milligan, D John Lee, David R Jackson, Andrew J Schaub, Joris Beld, Jesus F Barajas, Joseph J Hale, Ray Luo, Michael D Burkart, Shiou-Chuan Tsai
Molecular basis for interactions between an acyl carrier protein and a ketosynthase. Nature chemical biology 15 (7) (2019)
Cassandra E Callmann, Clare L M LeGuyader, Spencer T Burton, Matthew P Thompson, Robert Hennis, Christopher Barback, Niel M Henriksen, Warren C Chan, Matt J Jaremko, Jin Yang, Arnold Garcia, Michael D Burkart, Michael K Gilson, Jeremiah D Momper, Paul A Bertin, Nathan C Gianneschi
Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin. Journal of the American Chemical Society 141 (30) (2019)
Katherine Charov, Michael D Burkart
A Single Tool to Monitor Multiple Protein-Protein Interactions of the Escherichia coli Acyl Carrier Protein. ACS infectious diseases 5 (9) (2019)
Terra Sztain, Thomas G Bartholow, James Andrew McCammon, Michael D Burkart
Shifting the Hydrolysis Equilibrium of Substrate Loaded Acyl Carrier Proteins. Biochemistry 58 (34) (2019)
Terra Sztain, Ashay Patel, D John Lee, Tony D Davis, James Andrew McCammon, Michael D Burkart
Modifying the Thioester Linkage Affects the Structure of the Acyl Carrier Protein. Angewandte Chemie (International ed. in English) 58 (32) (2019)
Lorillee Tallorin, JiaLei Wang, Woojoo E Kim, Swagat Sahu, Nicolas M Kosa, Pu Yang, Matthew Thompson, Michael K Gilson, Peter I Frazier, Michael D Burkart, Nathan C Gianneschi
Discovering de novo peptide substrates for enzymes using machine learning. Nature communications 9 (1) (2018)
Sho Konno, James J La Clair, Michael D Burkart
Trapping the Complex Molecular Machinery of Polyketide and Fatty Acid Synthases with Tunable Silylcyanohydrin Crosslinkers. Angewandte Chemie (International ed. in English) 57 (52) (2018)
Woojoo E Kim, Ashay Patel, Gene H Hur, Peter Tufar, Michael G Wuo, J Andrew McCammon, Michael D Burkart
Mechanistic Probes for the Epimerization Domain of Nonribosomal Peptide Synthetases. Chembiochem : a European journal of chemical biology 20 (2) (2018)
Jennifer M Michaud, Luke R Thompson, Drishti Kaul, Josh L Espinoza, R Alexander Richter, Zhenjiang Zech Xu, Christopher Lee, Kevin M Pham, Charlotte M Beall, Francesca Malfatti, Farooq Azam, Rob Knight, Michael D Burkart, Christopher L Dupont, Kimberly A Prather
Taxon-specific aerosolization of bacteria and viruses in an experimental ocean-atmosphere mesocosm. Nature communications 9 (1) (2018)
Stephen Sarria, Thomas G Bartholow, Adam Verga, Michael D Burkart, Pamela Peralta-Yahya
Matching Protein Interfaces for Improved Medium-Chain Fatty Acid Production. ACS synthetic biology 7 (5) (2018)
Matt J Jaremko, D John Lee, Ashay Patel, Victoria Winslow, Stanley J Opella, J Andrew McCammon, Michael D Burkart
Manipulating Protein-Protein Interactions in Nonribosomal Peptide Synthetase Type II Peptidyl Carrier Proteins. Biochemistry 56 (40) (2017)
Brian León, Manoj K Kashyap, Warren C Chan, Kelsey A Krug, Januario E Castro, James J La Clair, Michael D Burkart
A Challenging Pie to Splice: Drugging the Spliceosome. Angewandte Chemie (International ed. in English) 56 (40) (2017)
Ian P McCulloch, James J La Clair, Matt J Jaremko, Michael D Burkart
Fluorescent Mechanism-Based Probe for Aerobic Flavin-Dependent Enzyme Activity. Chembiochem : a European journal of chemical biology 17 (17) (2016)

Michael D Burkart.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Michael D Burkart