Jarrod A Marto

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 41

Top Topics

Capillary Electrophoresis

Top Venues

Journal of medicinal chemistry

Nature communications

Nature chemical biology

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Yen-Der Li, Michelle W Ma, Muhammad Murtaza Hassan, Moritz Hunkeler, Mingxing Teng, Kedar Puvar, Justine C Rutter, Ryan J Lumpkin, Brittany Sandoval, Cyrus Y Jin, Anna M Schmoker, Scott B Ficarro, Hakyung Cheong, Rebecca J Metivier, Michelle Y Wang, Shawn Xu, Woong Sub Byun, Brian J Groendyke, Inchul You, Logan H Sigua, Isidoro Tavares, Charles Zou, Jonathan M Tsai, Paul M C Park, Hojong Yoon, Felix C Majewski, Haniya T Sperling, Jarrod A Marto, Jun Qi, Radosław P Nowak, Katherine Aleisha Donovan, Mikołaj Słabicki, Nathanael S Gray, Eric S Fischer, Benjamin L Ebert
Template-assisted covalent modification underlies activity of covalent molecular glues. Nature chemical biology (2024)
Zhengnian Li, Wen Chao Lu, Tyler S Beyett, Scott B Ficarro, Jie Jiang, Jason Tse, Audrey Yong-Ju Kim, Jarrod A Marto, Jianwei Che, Pasi A Jänne, Michael J Eck, Tinghu Zhang, Nathanael S Gray
ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. Journal of medicinal chemistry 67 (4) (2024)
Zhengnian Li, Jie Jiang, Scott B Ficarro, Tyler S Beyett, Ciric To, Isidoro Tavares, Yingde Zhu, Jiaqi Li, Michael J Eck, Pasi A Jänne, Jarrod A Marto, Tinghu Zhang, Jianwei Che, Nathanael S Gray
Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality. ACS central science 10 (6) (2024)
Yiling Elaine Chen, Xinzhou Ge, Kyla Woyshner, MeiLu McDermott, Antigoni Manousopoulou, Scott B Ficarro, Jarrod A Marto, Kexin Li, Leo David Wang, Jingyi Jessica Li
APIR: Aggregating Universal Proteomics Database Search Algorithms for Peptide Identification with FDR Control. Genomics, proteomics & bioinformatics 22 (2) (2024)
Zhengnian Li, Wen Chao Lu, Tyler S Beyett, Scott B Ficarro, Jie Jiang, Jason Tse, Audrey Yong-Ju Kim, Jarrod A Marto, Jianwei Che, Pasi A Jänne, Michael J Eck, Tinghu Zhang, Nathanael S Gray
ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. Journal of medicinal chemistry (2024)
Yen-Der Li, Michelle W Ma, Muhammad Murtaza Hassan, Moritz Hunkeler, Mingxing Teng, Kedar Puvar, Justine C Rutter, Ryan J Lumpkin, Brittany Sandoval, Cyrus Y Jin, Anna M Schmoker, Scott B Ficarro, Hakyung Cheong, Rebecca J Metivier, Michelle Y Wang, Shawn Xu, Woong Sub Byun, Brian J Groendyke, Inchul You, Logan H Sigua, Isidoro Tavares, Charles Zou, Jonathan M Tsai, Paul M C Park, Hojong Yoon, Felix C Majewski, Haniya T Sperling, Jarrod A Marto, Jun Qi, Radosław P Nowak, Katherine Aleisha Donovan, Mikołaj Słabicki, Nathanael S Gray, Eric S Fischer, Benjamin L Ebert
Template-assisted covalent modification underlies activity of covalent molecular glues. Nature chemical biology (2024)
Zhengnian Li, Wen Chao Lu, Tyler S Beyett, Scott B Ficarro, Jie Jiang, Jason Tse, Audrey Yong-Ju Kim, Jarrod A Marto, Jianwei Che, Pasi A Jänne, Michael J Eck, Tinghu Zhang, Nathanael S Gray
ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. Journal of medicinal chemistry 67 (4) (2024)
Zhengnian Li, Jie Jiang, Scott B Ficarro, Tyler S Beyett, Ciric To, Isidoro Tavares, Yingde Zhu, Jiaqi Li, Michael J Eck, Pasi A Jänne, Jarrod A Marto, Tinghu Zhang, Jianwei Che, Nathanael S Gray
Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality. ACS central science 10 (6) (2024)
Zhengnian Li, Wen Chao Lu, Tyler S Beyett, Scott B Ficarro, Jie Jiang, Jason Tse, Audrey Yong-Ju Kim, Jarrod A Marto, Jianwei Che, Pasi A Jänne, Michael J Eck, Tinghu Zhang, Nathanael S Gray
ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. Journal of medicinal chemistry 67 (4) (2024)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry (2023)
Wai Cheung Chan, Xiaoxi Liu, Robert S Magin, Nicholas M Girardi, Scott B Ficarro, Wanyi Hu, Maria I Tarazona Guzman, Cara A Starnbach, Alejandra Felix, Guillaume Adelmant, Anthony C Varca, Bin Hu, Ariana S Bratt, Ethan DaSilva, Nathan J Schauer, Isabella Jaen Maisonet, Emma K Dolen, Anthony X Ayala, Jarrod A Marto, Sara J Buhrlage
Accelerating inhibitor discovery for deubiquitinating enzymes. Nature communications 14 (1) (2023)
Wai Cheung Chan, Xiaoxi Liu, Robert S Magin, Nicholas M Girardi, Scott B Ficarro, Wanyi Hu, Maria I Tarazona Guzman, Cara A Starnbach, Alejandra Felix, Guillaume Adelmant, Anthony C Varca, Bin Hu, Ariana S Bratt, Ethan DaSilva, Nathan J Schauer, Isabella Jaen Maisonet, Emma K Dolen, Anthony X Ayala, Jarrod A Marto, Sara J Buhrlage
Accelerating inhibitor discovery for deubiquitinating enzymes. Nature communications 14 (1) (2023)
Wai Cheung Chan, Xiaoxi Liu, Robert S Magin, Nicholas M Girardi, Scott B Ficarro, Wanyi Hu, Maria I Tarazona Guzman, Cara A Starnbach, Alejandra Felix, Guillaume Adelmant, Anthony C Varca, Bin Hu, Ariana S Bratt, Ethan DaSilva, Nathan J Schauer, Isabella Jaen Maisonet, Emma K Dolen, Anthony X Ayala, Jarrod A Marto, Sara J Buhrlage
Accelerating inhibitor discovery for deubiquitinating enzymes. Nature communications 14 (1) (2023)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry 66 (5) (2023)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry 66 (5) (2023)
Justin T Cruite, Radosław P Nowak, Katherine Aleisha Donovan, Scott B Ficarro, Huang Huang, Hu Liu, Yingpeng Liu, Jarrod A Marto, Rebecca J Metivier, Eric S Fischer, Lyn H Jones
Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange. ACS medicinal chemistry letters 14 (11) (2023)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry (2023)
Gabriele Casirati, Andrea Cosentino, Adele Mucci, Mohammed S Mahmoud, Iratxe Ugarte Zabala, Jing Zeng, Scott B Ficarro, Denise Klatt, Christian Brendel, Alessandro Rambaldi, Jerome Ritz, Jarrod A Marto, Danilo Pellin, Daniel E Bauer, Scott A Armstrong, Pietro Genovese
Epitope editing enables targeted immunotherapy of acute myeloid leukaemia. Nature (2023)
Yen-Der Li, Michelle W Ma, Muhammad Murtaza Hassan, Moritz Hunkeler, Mingxing Teng, Kedar Puvar, Ryan Lumpkin, Brittany Sandoval, Cyrus Y Jin, Scott B Ficarro, Michelle Y Wang, Shawn Xu, Brian J Groendyke, Logan H Sigua, Isidoro Tavares, Charles Zou, Jonathan M Tsai, Paul M C Park, Hojong Yoon, Felix C Majewski, Jarrod A Marto, Jun Qi, Radosław P Nowak, Katherine Aleisha Donovan, Mikołaj Słabicki, Nathanael S Gray, Eric S Fischer, Benjamin L Ebert
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv : the preprint server for biology (2023)
Wen Chao Lu, Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B Ficarro, Isidoro Tavares, Jianwei Che, Audrey Y Kim, Xijun Zhu, Andrew Boghossian, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Stephen P Hinshaw, Behnam Nabet, Steven M Corsello, Nicholas Kwiatkowski, Jarrod A Marto, Tinghu Zhang, Nathanael S Gray
Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors. Journal of medicinal chemistry (2023)
Wen Chao Lu, Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li, Scott B Ficarro, Cynthia J Meyer, Dhiraj Sinha, Inchul You, Jason Tse, Zhixiang He, Wenzhi Ji, Jianwei Che, Audrey Y Kim, Tengteng Yu, Kenneth Wen, Kenneth C Anderson, Jarrod A Marto, Kenneth D Westover, Tinghu Zhang, Nathanael S Gray
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of medicinal chemistry 66 (5) (2023)
Wai Cheung Chan, Xiaoxi Liu, Robert S Magin, Nicholas M Girardi, Scott B Ficarro, Wanyi Hu, Maria I Tarazona Guzman, Cara A Starnbach, Alejandra Felix, Guillaume Adelmant, Anthony C Varca, Bin Hu, Ariana S Bratt, Ethan DaSilva, Nathan J Schauer, Isabella Jaen Maisonet, Emma K Dolen, Anthony X Ayala, Jarrod A Marto, Sara J Buhrlage
Accelerating inhibitor discovery for deubiquitinating enzymes. Nature communications 14 (1) (2023)
Yen-Der Li, Michelle W Ma, Muhammad Murtaza Hassan, Moritz Hunkeler, Mingxing Teng, Kedar Puvar, Ryan Lumpkin, Brittany Sandoval, Cyrus Y Jin, Scott B Ficarro, Michelle Y Wang, Shawn Xu, Brian J Groendyke, Logan H Sigua, Isidoro Tavares, Charles Zou, Jonathan M Tsai, Paul M C Park, Hojong Yoon, Felix C Majewski, Jarrod A Marto, Jun Qi, Radosław P Nowak, Katherine Aleisha Donovan, Mikołaj Słabicki, Nathanael S Gray, Eric S Fischer, Benjamin L Ebert
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv : the preprint server for biology (2023)
He Zhu, J Scott Mellors, Wai Cheung Chan, J Will Thompson, Scott B Ficarro, Isidoro Tavares, Ariana S Bratt, Jens Decker, Michael Krause, Gary Kruppa, Sara J Buhrlage, Jarrod A Marto
On-Chip Preconcentration Microchip Capillary Electrophoresis Based CE-PRM-LIVE for High-Throughput Selectivity Profiling of Deubiquitinase Inhibitors. Analytical chemistry 94 (27) (2022)
Peng Wei, Alex J Bott, Ahmad A Cluntun, Jeffrey T Morgan, Corey N Cunningham, John C Schell, Yeyun Ouyang, Scott B Ficarro, Jarrod A Marto, Nika N Danial, Ralph J DeBerardinis, Jared Rutter
Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway. Science advances 8 (39) (2022)
Wai Cheung Chan, Shabnam Sharifzadeh, Sara J Buhrlage, Jarrod A Marto
Chemoproteomic methods for covalent drug discovery. Chemical Society reviews 50 (15) (2021)
He Zhu, Scott B Ficarro, William M Alexander, Laura E Fleming, Guillaume Adelmant, Tinghu Zhang, Matthew Willetts, Jens Decker, Sven Brehmer, Michael Krause, Michael P East, Nathanael S Gray, Gary L Johnson, Gary Kruppa, Jarrod A Marto
PRM-LIVE with Trapped Ion Mobility Spectrometry and Its Application in Selectivity Profiling of Kinase Inhibitors. Analytical chemistry 93 (41) (2021)
Mingxing Teng, Jie Jiang, Scott B Ficarro, Hyuk-Soo Seo, Jae Hyun Bae, Katherine Aleisha Donovan, Eric S Fischer, Tinghu Zhang, Sirano Dhe-Paganon, Jarrod A Marto, Nathanael S Gray
Exploring Ligand-Directed N-Acyl-N-alkylsulfonamide-Based Acylation Chemistry for Potential Targeted Degrader Development. ACS medicinal chemistry letters 12 (8) (2021)
Jekaterina Vohhodina, Liana J Goehring, Ben Liu, Qing Kong, Vladimir V Botchkarev, Mai Huynh, Zhiqi Liu, Fieda O Abderazzaq, Allison P Clark, Scott B Ficarro, Jarrod A Marto, Elodie Hatchi, David M Livingston
BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage. Nature communications 12 (1) (2021)
Christian Dubiella, Benika J Pinch, Kazuhiro Koikawa, Daniel Zaidman, Evon Poon, Theresa D Manz, Behnam Nabet, Shuning He, Efrat Resnick, Adi Rogel, Ellen M Langer, Colin J Daniel, Hyuk-Soo Seo, Ying Chen, Guillaume Adelmant, Shabnam Sharifzadeh, Scott B Ficarro, Yann Jamin, Barbara Martins da Costa, Mark W Zimmerman, Xiaolan Lian, Shin Kibe, Shingo Kozono, Zainab M Doctor, Christopher M Browne, Annan Yang, Liat Stoler-Barak, Richa B Shah, Nicholas E Vangos, Ezekiel A Geffken, Roni Oren, Eriko Koide, Samuel Sidi, Ziv Shulman, Chu Wang, Jarrod A Marto, Sirano Dhe-Paganon, Thomas Look, Xiao Zhen Zhou, Kun Ping Lu, Rosalie C Sears, Louis Chesler, Nathanael S Gray, Nir London
Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nature chemical biology 17 (9) (2021)
Jing Yang, Ellen L Weisberg, Xiaoxi Liu, Robert S Magin, Wai Cheung Chan, Bin Hu, Nathan J Schauer, Shengzhe Zhang, Ilaria Lamberto, Laura Doherty, Chengcheng Meng, Martin Sattler, Lucia Cabal-Hierro, Eric Winer, Richard Stone, Jarrod A Marto, James D Griffin, Sara J Buhrlage
Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2. Leukemia (2021)
Stefan Haemmig, Dafeng Yang, Xinghui Sun, Debapria Das, Siavash Ghaffari, Roberto Molinaro, Lei Chen, Yihuan Deng, Dan Freeman, Norman Moullan, Yevgenia Tesmenitsky, A K M Khyrul Wara, Viorel Simion, Eugenia Shvartz, James F Lee, Tianlun Yang, Galina Sukova, Jarrod A Marto, Peter H Stone, Warren L Lee, Johan Auwerx, Peter Libby, Mark W Feinberg
Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence. Science translational medicine 12 (531) (2021)
Nathan J Schauer, Xiaoxi Liu, Robert S Magin, Laura M Doherty, Wai Cheung Chan, Scott B Ficarro, Wanyi Hu, Rebekka M Roberts, Roxana E Iacob, Björn Stolte, Andrew O Giacomelli, Sumner Perera, Kyle McKay, Sarah A Boswell, Ellen L Weisberg, Arghya Ray, Dharminder Chauhan, Sirano Dhe-Paganon, Ken C Anderson, James D Griffin, Jianing Li, William C Hahn, Peter Karl Sorger, John R Engen, Kimberly Stegmaier, Jarrod A Marto, Sara J Buhrlage
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Scientific reports 10 (1) (2020)
Arijit A Adhikari, Tom C M Seegar, Scott B Ficarro, Megan D McCurry, Deepti Ramachandran, Lina Yao, Snehal N Chaudhari, Sula Ndousse-Fetter, Alexander S Banks, Jarrod A Marto, Stephen C Blacklow, A Sloan Devlin
Development of a covalent inhibitor of gut bacterial bile salt hydrolases. Nature chemical biology 16 (3) (2020)
Accalia Fu, Juan Carlos Alvarez-Perez, Daina Avizonis, Tatsuya Kin, Scott B Ficarro, Dong Wook Choi, Esra Karakose, Mehmet G Badur, Lindsay Evans, Carolina Rosselot, Gaelle Bridon, Gregory H Bird, Hyuk-Soo Seo, Sirano Dhe-Paganon, Jurre J Kamphorst, Andrew F Stewart, A M James Shapiro, Jarrod A Marto, Loren D Walensky, Russell G Jones, Adolfo Garcia-Ocana, Nika N Danial
Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation. Nature metabolism 2 (5) (2020)
Connor S Clairmont, Prabha Sarangi, Karthikeyan Ponnienselvan, Lucas D Galli, Isabelle Csete, Lisa Moreau, Guillaume Adelmant, Dipanjan Chowdhury, Jarrod A Marto, Alan D' Andrea
TRIP13 regulates DNA repair pathway choice through REV7 conformational change. Nature cell biology 22 (1) (2020)
Viorel Simion, Haoyang Zhou, Stefan Haemmig, Jacob B Pierce, Shanelle Mendes, Yevgenia Tesmenitsky, Daniel Pérez-Cremades, James F Lee, Alex F Chen, Nicoletta Ronda, Bianca Papotti, Jarrod A Marto, Mark W Feinberg
A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus. Nature communications 11 (1) (2020)
Benika J Pinch, Zainab M Doctor, Behnam Nabet, Christopher M Browne, Hyuk-Soo Seo, Mikaela L Mohardt, Shingo Kozono, Xiaolan Lian, Theresa D Manz, Yujin Chun, Shin Kibe, Daniel Zaidman, Dina Daitchman, Zoe C Yeoh, Nicholas E Vangos, Ezekiel A Geffken, Li Tan, Scott B Ficarro, Nir London, Jarrod A Marto, Stephen Buratowski, Sirano Dhe-Paganon, Xiao Zhen Zhou, Kun Ping Lu, Nathanael S Gray
Identification of a potent and selective covalent Pin1 inhibitor. Nature chemical biology 16 (9) (2020)
Edward C Twomey, Zhejian Ji, Thomas E Wales, Nicholas O Bodnar, Scott B Ficarro, Jarrod A Marto, John R Engen, Tom A Rapoport
Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science (New York, N.Y.) 365 (6452) (2019)
Sanchez M Jarrett, Tom C M Seegar, Mark Andrews, Guillaume Adelmant, Jarrod A Marto, Jon C Aster, Stephen C Blacklow
Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling. Science signaling 12 (606) (2019)
Xiao-Feng Zheng, Sanket S Acharya, Katherine N Choe, Kumar Nikhil, Guillaume Adelmant, Shakti Ranjan Satapathy, Samanta Sharma, Keith Viccaro, Sandeep Rana, Amarnath Natarajan, Piotr Sicinski, Jarrod A Marto, Kavita Shah, Dipanjan Chowdhury
A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1. Nature communications 10 (1) (2019)