Richard F Loeser (Richard Loeser)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 40

Top Venues

Arthritis & rheumatology (Hoboken, N.J.)

Arthritis care & research

bioRxiv : the preprint server for biology

Nature reviews. Rheumatology

University of North Carolina

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of North Carolina Mar 01 2014

United States

Professor :: Medicine

Publications

Nicole E Kramer, Philip R Coryell, Susan D'Costa, Eliza Thulson, Seyoun Byun, HyunAh Kim, Sylvie M Parkus, Marielle L Bond, Jacqueline Yalin S Shin Sahin, Susanna Chubinskaya, Michael I Love, Karen L Mohlke, Brian O Diekman, Richard F Loeser, Douglas H Phanstiel
Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk. bioRxiv : the preprint server for biology (2024)
Brian O Diekman, Richard F Loeser
DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair. Arthritis & rheumatology (Hoboken, N.J.) 76 (6) (2024)
Nicole E Kramer, Philip R Coryell, Susan D'Costa, Eliza Thulson, Seyoun Byun, HyunAh Kim, Sylvie M Parkus, Marielle L Bond, Jacqueline Yalin S Shin Sahin, Susanna Chubinskaya, Michael I Love, Karen L Mohlke, Brian O Diekman, Richard F Loeser, Douglas H Phanstiel
Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk. bioRxiv : the preprint server for biology (2024)
Ali Mobasheri, Richard F Loeser
Clinical phenotypes, molecular endotypes and theratypes in OA therapeutic development. Nature reviews. Rheumatology (2024)
Brian O Diekman, Richard F Loeser
DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair. Arthritis & rheumatology (Hoboken, N.J.) 76 (6) (2024)
Michael Z Miao, Janice S Lee, Kenneth M Yamada, Richard F Loeser
Integrin signalling in joint development, homeostasis and osteoarthritis. Nature reviews. Rheumatology 20 (8) (2024)
Brian O Diekman, Richard F Loeser
DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair. Arthritis & rheumatology (Hoboken, N.J.) (2024)
Brian O Diekman, Richard F Loeser
DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair. Arthritis & rheumatology (Hoboken, N.J.) 76 (6) (2024)
Hope D Welhaven, Avery H Wefley, Brian Bothner, Stephen P Messier, Richard F Loeser, Ronald K June
The metabolome of individuals with knee osteoarthritis is influenced by 18-months of an exercise and weight loss intervention and sex: the IDEA trial. bioRxiv : the preprint server for biology (2024)
Brian O Diekman, Richard F Loeser
DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair. Arthritis & rheumatology (Hoboken, N.J.) (2024)
Michael Z Miao, Janice S Lee, Kenneth M Yamada, Richard F Loeser
Integrin signalling in joint development, homeostasis and osteoarthritis. Nature reviews. Rheumatology (2024)
Paul T Kopp, Catherine Yang, Heidi Yang, Jeffrey N Katz, A David Paltiel, David John Hunter, Leigh F Callahan, Shannon L Mihalko, Jovita J Newman, Paul DeVita, Richard F Loeser, Gary D Miller, Stephen P Messier, Elena Losina
Cost-Effectiveness of Community-Based Diet and Exercise for Patients with Knee Osteoarthritis and Obesity or Overweight. Arthritis care & research (2024)
Hope D Welhaven, Avery H Wefley, Brian Bothner, Stephen P Messier, Richard F Loeser, Ronald K June
The metabolome of individuals with knee osteoarthritis is influenced by 18-months of an exercise and weight loss intervention and sex: the IDEA trial. bioRxiv : the preprint server for biology (2024)
Paul T Kopp, Catherine Yang, Heidi Yang, Jeffrey N Katz, A David Paltiel, David John Hunter, Leigh F Callahan, Shannon L Mihalko, Jovita J Newman, Paul DeVita, Richard F Loeser, Gary D Miller, Stephen P Messier, Elena Losina
Cost-Effectiveness of Community-Based Diet and Exercise for Patients with Knee Osteoarthritis and Obesity or Overweight. Arthritis care & research 76 (7) (2024)
Michael Z Miao, Janice S Lee, Kenneth M Yamada, Richard F Loeser
Publisher Correction: Integrin signalling in joint development, homeostasis and osteoarthritis. Nature reviews. Rheumatology (2024)
Ali Mobasheri, Richard F Loeser
Clinical phenotypes, molecular endotypes and theratypes in OA therapeutic development. Nature reviews. Rheumatology 20 (9) (2024)
Paul T Kopp, Catherine Yang, Heidi Yang, Jeffrey N Katz, A David Paltiel, David John Hunter, Leigh F Callahan, Shannon L Mihalko, Jovita J Newman, Paul DeVita, Richard F Loeser, Gary D Miller, Stephen P Messier, Elena Losina
Cost-Effectiveness of Community-Based Diet and Exercise for Patients with Knee Osteoarthritis and Obesity or Overweight. Arthritis care & research 76 (7) (2024)
Paul T Kopp, Catherine Yang, Heidi Yang, Jeffrey N Katz, A David Paltiel, David John Hunter, Leigh F Callahan, Shannon L Mihalko, Jovita J Newman, Paul DeVita, Richard F Loeser, Gary D Miller, Stephen P Messier, Elena Losina
Cost-Effectiveness of Community-Based Diet and Exercise for Patients with Knee Osteoarthritis and Obesity or Overweight. Arthritis care & research (2024)
Michael Z Miao, Qian Peter Su, Yang Cui, Edward S M Bahnson, Gang Li, Menglin Wang, Yuchen Yang, John A Collins, Di Wu, Qisheng Gu, Susan Chubinskaya, Brian O Diekman, Kenneth M Yamada, Richard F Loeser
Redox-active endosomes mediate α5β1 integrin signaling and promote chondrocyte matrix metalloproteinase production in osteoarthritis. Science signaling 16 (809) (2023)
Michaela E Copp, Jacqueline Yalin S Shin Sahin, Hannon L Brown, Kirti R Nimmala, Susan Chubinskaya, John A Collins, Richard F Loeser, Brian O Diekman
SIRT6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes. bioRxiv : the preprint server for biology (2023)
Michaela E Copp, Jacqueline Yalin S Shin Sahin, Hannon L Brown, Kirti R Nimmala, Susan Chubinskaya, John A Collins, Richard F Loeser, Brian O Diekman
SIRT6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes. bioRxiv : the preprint server for biology (2023)
Richard F Loeser
Using Mice to Model Human Osteoarthritis: Age, Biological Sex, and Pain Matter. Arthritis & rheumatology (Hoboken, N.J.) (2023)
Michaela E Copp, Jacqueline Yalin S Shin Sahin, Hannon L Brown, Kirti R Nimmala, Susan Chubinskaya, John A Collins, Richard F Loeser, Brian O Diekman
SIRT6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes. bioRxiv : the preprint server for biology (2023)
John A Collins, C James Kim, Ashley Coleman, Abreah Little, Matheus M Perez, Emily J Clarke, Brian Diekman, Mandy J Peffers, Susanna Chubinskaya, Ryan E Tomlinson, Theresa A Freeman, Richard F Loeser
Cartilage-specific Sirt6 deficiency represses IGF-1 and enhances osteoarthritis severity in mice. Annals of the rheumatic diseases (2023)
Stephen P Messier, Malia E Gill, Shannon L Mihalko, Daniel P Beavers, Kate Queen, Gary D Miller, Elena Losina, Jeffrey N Katz, Richard F Loeser, Paul DeVita, David John Hunter, Sara A Quandt, Mary F Lyles, David Hudson, Leigh F Callahan
Clinical, Health-Related Quality of Life, and Gait Differences Among Obesity Classes in Adults with Knee Osteoarthritis. Arthritis care & research (2023)
Eliza Thulson, Eric S Davis, Susan D'Costa, Philip R Coryell, Nicole E Kramer, Karen L Mohlke, Richard F Loeser, Brian O Diekman, Douglas H Phanstiel
3D chromatin structure in chondrocytes identifies putative osteoarthritis risk genes. Genetics 222 (4) (2022)
Yvonne M Golightly, Kristin Y Shiue, Maryalice Nocera, Ali Guermazi, John Cantrell, Jordan B Renner, Darin A Padua, Kenneth L Cameron, Steven J Svoboda, Joanne M Jordan, Richard F Loeser, Virginia B Kraus, L Stefan Lohmander, Anthony I Beutler, Stephen W Marshall
Association of Traumatic Knee Injury with Radiographic Evidence of Knee Osteoarthritis in Military Officers. Arthritis care & research (2022)
Richard F Loeser, Philip R Coryell
Correspondence on 'Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7' by Zhang et al . Annals of the rheumatic diseases (2022)
Richard F Loeser, Philip R Coryell, Alexandra R Armstrong, John A Collins, Priya Gopalakrishnan, Katie A McDermott, Qitao Ran, Cathy S Carlson
Overexpression of Peroxiredoxin 3 in Cartilage Reduces the Severity of Age-Related Osteoarthritis But Not Surgically Induced Osteoarthritis in Mice. ACR open rheumatology 4 (5) (2022)
Yvonne M Golightly, Kristin Y Shiue, Maryalice Nocera, Ali Guermazi, John Cantrell, Jordan B Renner, Darin A Padua, Kenneth L Cameron, Steven J Svoboda, Joanne M Jordan, Richard F Loeser, Virginia B Kraus, L Stefan Lohmander, Anthony I Beutler, Stephen W Marshall
Association of Traumatic Knee Injury With Radiographic Evidence of Knee Osteoarthritis in Military Officers. Arthritis care & research (2022)
Michaela E Copp, Susan Chubinskaya, Daniel N Bracey, Jacqueline Yalin S Shin Sahin, Garrett A Sessions, Richard F Loeser, Brian O Diekman
Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis. Aging cell 21 (9) (2022)
Richard F Loeser, Liubov Arbeeva, Kathryn Kelley, Anthony A Fodor, Shan Sun, Veronica Ulici, Lara Longobardi, Yang Cui, Delisha A Stewart, Susan J Sumner, M Andrea Azcarate-Peril, R Balfour Sartor, Ian M Carroll, Jordan B Renner, Joanne M Jordan, Amanda E Nelson
Association of Increased Serum Lipopolysaccharide but not Microbial Dysbiosis with Obesity-related Osteoarthritis. Arthritis & rheumatology (Hoboken, N.J.) (2021)
Stephen P Messier, Jovita J Newman, Matthew J Scarlett, Shannon L Mihalko, Gary D Miller, Barbara J Nicklas, Paul DeVita, David John Hunter, Mary F Lyles, Felix Eckstein, Ali Guermazi, Richard F Loeser, Daniel P Beavers
Changes in body weight and knee pain in adults with knee osteoarthritis 3.5 years after completing diet and exercise interventions. Arthritis care & research (2021)
Xiaotong Jiang, Amanda E Nelson, Rebecca J Cleveland, Daniel P Beavers, Todd A Schwartz, Liubov Arbeeva, Carolina Alvarez, Leigh F Callahan, Stephen Messier, Richard F Loeser, Michael R Kosorok
Precision Medicine Approach to Develop and Internally Validate Optimal Exercise and Weight-Loss Treatments for Overweight and Obese Adults With Knee Osteoarthritis: Data From a Single-Center Randomized Trial. Arthritis care & research 73 (5) (2021)
Tieshi Li, Susan Chubinskaya, Alessandra Esposito, Xin Jin, Lidia Tagliafierro, Richard F Loeser, Arnavaz A Hakimiyan, Lara Longobardi, Huseyin Ozkan, Anna Spagnoli
TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis. Science translational medicine 11 (491) (2020)
Richard F Loeser, John A Collins, Brian O Diekman, Cathy S Carlson
Reply. Arthritis & rheumatology (Hoboken, N.J.) 72 (12) (2020)
Richard F Loeser, Kathryn L Kelley, Alexandra Armstrong, John A Collins, Brian O Diekman, Cathy S Carlson
Deletion of JNK Enhances Senescence in Joint Tissues and Increases the Severity of Age-Related Osteoarthritis in Mice. Arthritis & rheumatology (Hoboken, N.J.) 72 (10) (2020)
Philip R Coryell, Brian O Diekman, Richard F Loeser
Mechanisms and therapeutic implications of cellular senescence in osteoarthritis. Nature reviews. Rheumatology 17 (1) (2020)
Brian O Diekman, Garrett A Sessions, John A Collins, Anne K Knecht, Susan L Strum, Natalia K Mitin, Cathy S Carlson, Richard F Loeser, Norman E Sharpless
Expression of p16INK 4a is a biomarker of chondrocyte aging but does not cause osteoarthritis. Aging cell 17 (4) (2018)
Kimberly J Nelson, Jesalyn A Bolduc, Hanzhi Wu, John A Collins, Elizabeth A Burke, Julie A Reisz, Chananat Klomsiri, Scott T Wood, Raghunatha R Yammani, Leslie B Poole, Cristina M Furdui, Richard F Loeser
H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes. The Journal of biological chemistry 293 (42) (2018)

Richard F Loeser.css-eqlu8i{font-size:small;padding-left:4px;} (Richard Loeser)

Publication Activity (10 Years)

Top Topics

Top Venues

Richard F Loeser (Richard Loeser)