Shamil R Sunyaev (S R Sunyaev, Shamil Sunyaev)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 43

Top Topics

Positive Airway Pressure

Helicobacter Pylori

Arabidopsis Thaliana

Top Venues

Nature genetics

Research square

This page only lists publications with an associated author ORCID identifier.

Publications

Shilpa Nadimpalli Kobren, Mikhail A Moldovan, Rebecca M Reimers, Daniel Traviglia, Xinyun Li, Danielle Barnum, Alexander Veit, Julian Willett, Michele Berselli, William Ronchetti, Richard Sherwood, Joel Krier, Isaac S Kohane, null null, Shamil R Sunyaev
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations. bioRxiv : the preprint server for biology (2024)
Sumaiya Nazeen, Xinyuan Wang, Dina Zielinski, Isabel Lam, Erinc Hallacli, Ping Xu, Elizabeth Ethier, Ronya Strom, Camila A Zanella, Vanitha Nithianandam, Dylan Ritter, Alexander Henderson, Nathalie Saurat, Jalwa Afroz, Andrew Nutter-Upham, Hadar Benyamini, Joseph Copty, Shyamsundar Ravishankar, Autumn Morrow, Jonathan Mitchel, Drew Neavin, Renuka Gupta, Nona Farbehi, Jennifer Grundman, Richard H Myers, Clemens R Scherzer, John Q Trojanowski, Vivianna M Van Deerlin, Antony A Cooper, Edward B Lee, Yaniv Erlich, Susan Lindquist, Jian Peng, Daniel H Geschwind, Joseph Powell, Lorenz Studer, Mel B Feany, Shamil R Sunyaev, Vikram Khurana
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. bioRxiv : the preprint server for biology (2024)
Sumaiya Nazeen, Xinyuan Wang, Dina Zielinski, Isabel Lam, Erinc Hallacli, Ping Xu, Elizabeth Ethier, Ronya Strom, Camila A Zanella, Vanitha Nithianandam, Dylan Ritter, Alexander Henderson, Nathalie Saurat, Jalwa Afroz, Andrew Nutter-Upham, Hadar Benyamini, Joseph Copty, Shyamsundar Ravishankar, Autumn Morrow, Jonathan Mitchel, Drew Neavin, Renuka Gupta, Nona Farbehi, Jennifer Grundman, Richard H Myers, Clemens R Scherzer, John Q Trojanowski, Vivianna M Van Deerlin, Antony A Cooper, Edward B Lee, Yaniv Erlich, Susan Lindquist, Jian Peng, Daniel H Geschwind, Joseph Powell, Lorenz Studer, Mel B Feany, Shamil R Sunyaev, Vikram Khurana
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. bioRxiv : the preprint server for biology (2024)
Matthew R Lincoln, Noah Connally, Pierre-Paul Axisa, Christiane Gasperi, Mitja Mitrovic, David A van Heel, Cisca Wijmenga, Sebo Withoff, Iris H Jonkers, Leonid Padyukov, null null, Stephen S Rich, Robert R Graham, Patrick M Gaffney, Carl D Langefeld, Timothy J Vyse, David A Hafler, Sung Chun, Shamil R Sunyaev, Chris Cotsapas
Genetic mapping across autoimmune diseases reveals shared associations and mechanisms. Nature genetics (2024)
Shilpa Nadimpalli Kobren, Mikhail A Moldovan, Rebecca M Reimers, Daniel Traviglia, Xinyun Li, Danielle Barnum, Alexander Veit, Julian Willett, Michele Berselli, William Ronchetti, Richard Sherwood, Joel Krier, Isaac S Kohane, null null, Shamil R Sunyaev
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations. bioRxiv : the preprint server for biology (2024)
Matthew R Lincoln, Noah Connally, Pierre-Paul Axisa, Christiane Gasperi, Mitja Mitrovic, David A van Heel, Cisca Wijmenga, Sebo Withoff, Iris H Jonkers, Leonid Padyukov, null null, Stephen S Rich, Robert R Graham, Patrick M Gaffney, Carl D Langefeld, Timothy J Vyse, David A Hafler, Sung Chun, Shamil R Sunyaev, Chris Cotsapas
Genetic mapping across autoimmune diseases reveals shared associations and mechanisms. Nature genetics 56 (5) (2024)
Matthew R Lincoln, Noah Connally, Pierre-Paul Axisa, Christiane Gasperi, Mitja Mitrovic, David A van Heel, Cisca Wijmenga, Sebo Withoff, Iris H Jonkers, Leonid Padyukov, null null, Stephen S Rich, Robert R Graham, Patrick M Gaffney, Carl D Langefeld, Timothy J Vyse, David A Hafler, Sung Chun, Shamil R Sunyaev, Chris Cotsapas
Genetic mapping across autoimmune diseases reveals shared associations and mechanisms. Nature genetics 56 (5) (2024)
Shilpa Nadimpalli Kobren, Mikhail A Moldovan, Rebecca M Reimers, Daniel Traviglia, Xinyun Li, Danielle Barnum, Alexander Veit, Julian Willett, Michele Berselli, William Ronchetti, Richard Sherwood, Joel Krier, Isaac S Kohane, null null, Shamil R Sunyaev
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations. bioRxiv : the preprint server for biology (2024)
Martin Jinye Zhang, Arun Durvasula, Colby Chiang, Evan M Koch, Benjamin J Strober, Huwenbo Shi, Alison R Barton, Samuel Sungil Kim, Omer Weissbrod, Po-Ru Loh, Steven Gazal, Shamil R Sunyaev, Alkes L Price
Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection. Research square (2023)
Martin Jinye Zhang, Arun Durvasula, Colby Chiang, Evan M Koch, Benjamin J Strober, Huwenbo Shi, Alison R Barton, Samuel Sungil Kim, Omer Weissbrod, Po-Ru Loh, Steven Gazal, Shamil R Sunyaev, Alkes L Price
Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection. Research square (2023)
Martin Jinye Zhang, Alkes L Price, Arun Durvasula, Colby Chiang, Evan Koch, Armin Schoech, Benjamin Strober, Huwenbo Shi, Alison R Barton, Samuel Sungil Kim, Omer Weissbrod, Po-Ru Loh, Steven Gazal, Shamil R Sunyaev
Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection. Research square (2023)
Martin Jinye Zhang, Alkes L Price, Arun Durvasula, Colby Chiang, Evan Koch, Armin Schoech, Benjamin Strober, Huwenbo Shi, Alison R Barton, Samuel Sungil Kim, Omer Weissbrod, Po-Ru Loh, Steven Gazal, Shamil R Sunyaev
Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection. Research square (2023)
Vladimir B Seplyarskiy, Evan M Koch, Daniel J Lee, Joshua S Lichtman, Harding H Luan, Shamil R Sunyaev
A mutation rate model at the basepair resolution identifies the mutagenic effect of polymerase III transcription. Nature genetics (2023)
Hong Gao, Tobias Hamp, Jeffrey Ede, Joshua G Schraiber, Jeremy F McRae, Moriel H Singer-Berk, Yanshen Yang, Anastasia S D Dietrich, Petko P Fiziev, Lukas F K Kuderna, Laksshman Sundaram, Yibing Wu, Aashish N Adhikari, Yair Field, Chen Chen, Serafim Batzoglou, François Aguet, Gabrielle Lemire, Rebecca Reimers, Daniel J Balick, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rousselle, Felipe Ennes Silva, Lidia Agueda, Julie Marie Blanc, Marta Gut, Dorien de Vries, Ian B Goodhead, Ronald Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idrissa S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Fabiano Rodrigues de Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Pires Farias, João Valsecchi do Amaral, Mariluce Rezende Messias, Maria N F da Silva, Mihir Trivedi, Rogério Vieira Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane E Phillips-Conroy, Gregory K Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernández-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dong-Dong Wu, Long Zhou, Yong Shao, Guo-Jie Zhang, Julius D Keyyu, Sascha Knauf, Quyen Hanh Do, Esther Lizano, Stefan Merker, Arcadi Navarro, Thomas Bataillon, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Boon-Ooi Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Glynne Gut, Amanda Dawn Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M D Beck, Govindhaswamy Umapathy, Christian Roos, Jean Phillipe Boubli, Monkol Lek, Shamil R Sunyaev, Anne H O'Donnell-Luria, Michael J Bamshad, Jinbo Xu, Jeffrey Rogers, Tomas Marques-Bonet, Kyle Kai-How Farh
The landscape of tolerated genetic variation in humans and primates. Science (New York, N.Y.) 380 (6648) (2023)
R J McGinty, Shamil R Sunyaev
Revisiting mutagenesis at non-B DNA motifs in the human genome. Nature structural & molecular biology (2023)
Martin Jinye Zhang, Arun Durvasula, Colby Chiang, Evan M Koch, Benjamin J Strober, Huwenbo Shi, Alison R Barton, Samuel Sungil Kim, Omer Weissbrod, Po-Ru Loh, Steven Gazal, Shamil R Sunyaev, Alkes L Price
Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection. Research square (2023)
Felix Dietlein, Alex B Wang, Christian Fagre, Anran Tang, Nicolle J M Besselink, Edwin Cuppen, Chunliang Li, Shamil R Sunyaev, James T Neal, Eliezer Van Allen
Genome-wide analysis of somatic noncoding mutation patterns in cancer. Science (New York, N.Y.) 376 (6589) (2022)
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palmer, David R Hillman, Jerome I Rotter, Craig L Hanis, John A Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R Sunyaev
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits. PLoS genetics 18 (12) (2022)
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palmer, David R Hillman, Jerome I Rotter, Craig L Hanis, John A Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R Sunyaev
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits. PLoS genetics 18 (12) (2022)
Noah James Connally, Sumaiya Nazeen, Daniel Lee, Huwenbo Shi, John Stamatoyannopoulos, Sung Chun, Chris Cotsapas, Christopher A Cassa, Shamil R Sunyaev
The missing link between genetic association and regulatory function. eLife 11 (2022)
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palmer, David R Hillman, Jerome I Rotter, Craig L Hanis, John A Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R Sunyaev
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits. PLoS genetics 18 (12) (2022)
Noah James Connally, Sumaiya Nazeen, Daniel Lee, Huwenbo Shi, John Stamatoyannopoulos, Sung Chun, Chris Cotsapas, Christopher A Cassa, Shamil R Sunyaev
The missing link between genetic association and regulatory function. eLife 11 (2022)
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palmer, David R Hillman, Jerome I Rotter, Craig L Hanis, John A Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R Sunyaev
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits. PLoS genetics 18 (12) (2022)
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palmer, David R Hillman, Jerome I Rotter, Craig L Hanis, John A Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R Sunyaev
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits. PLoS genetics 18 (12) (2022)
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palmer, David R Hillman, Jerome I Rotter, Craig L Hanis, John A Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R Sunyaev
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits. PLoS genetics 18 (12) (2022)
Noah James Connally, Sumaiya Nazeen, Daniel Lee, Huwenbo Shi, John Stamatoyannopoulos, Sung Chun, Chris Cotsapas, Christopher A Cassa, Shamil R Sunyaev
The missing link between genetic association and regulatory function. eLife 11 (2022)
Noah James Connally, Sumaiya Nazeen, Daniel Lee, Huwenbo Shi, John Stamatoyannopoulos, Sung Chun, Chris Cotsapas, Christopher A Cassa, Shamil R Sunyaev
The missing link between genetic association and regulatory function. eLife 11 (2022)
Noah James Connally, Sumaiya Nazeen, Daniel Lee, Huwenbo Shi, John Stamatoyannopoulos, Sung Chun, Chris Cotsapas, Christopher A Cassa, Shamil R Sunyaev
The missing link between genetic association and regulatory function. eLife 11 (2022)
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E Cade, Heming Wang, Tamar Sofer, Daniel S Evans, Katie L Stone, Sina A Gharib, Sutapa Mukherjee, Lyle J Palmer, David R Hillman, Jerome I Rotter, Craig L Hanis, John A Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R Sunyaev
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits. PLoS genetics 18 (12) (2022)
Noah James Connally, Sumaiya Nazeen, Daniel Lee, Huwenbo Shi, John Stamatoyannopoulos, Sung Chun, Chris Cotsapas, Christopher A Cassa, Shamil R Sunyaev
The missing link between genetic association and regulatory function. eLife 11 (2022)
Benedict Wieters, Kim A Steige, Fei He, Evan M Koch, Sebastian E Ramos-Onsins, Hongya Gu, Ya-Long Guo, Shamil R Sunyaev, Juliette de Meaux
Polygenic adaptation of rosette growth in Arabidopsis thaliana. PLoS genetics 17 (1) (2021)
Vladimir B Seplyarskiy, Ruslan A Soldatov, Evan M Koch, Ryan J McGinty, Jakob M Goldmann, Ryan D Hernandez, Kathleen Barnes, Adolfo Correa, Esteban González Burchard, Patrick T Ellinor, Stephen T McGarvey, Braxton D Mitchell, Ramachandran S Vasan, Susan Redline, Edwin K Silverman, Scott T Weiss, Donna K Arnett, John Blangero, Eric Boerwinkle, Jiang He, Courtney G Montgomery, D C Rao, Jerome I Rotter, Kent D Taylor, Jennifer A Brody, Yii-Der Ida Chen, Lisa de Las Fuentes, Chii-Min Hwa, Stephen S Rich, Ani W Manichaikul, Josyf C Mychaleckyi, Nicholette D D Allred, Jennifer A Smith, Sharon L R Kardia, Patricia A Peyser, Lawrence F Bielak, Timothy D O'Connor, Leslie S Emery, null null, null null, Christian Gilissen, Wendy S W Wong, Peter V Kharchenko, Shamil R Sunyaev
Population sequencing data reveal a compendium of mutational processes in the human germ line. Science (New York, N.Y.) 373 (6558) (2021)
Xihao Li, Zilin Li, Hufeng Zhou, Sheila M Gaynor, Yaowu Liu, Han Chen, Ryan Sun, Rounak Dey, Donna K Arnett, Stella Aslibekyan, Christie M Ballantyne, Lawrence F Bielak, John E Blangero, Eric Boerwinkle, Donald W Bowden, Jai G Broome, Matthew P Conomos, Adolfo Correa, L Adrienne Cupples, Joanne E Curran, Barry I Freedman, Xiuqing Guo, George Hindy, Marguerite R Irvin, Sharon L R Kardia, Sekar Kathiresan, Alyna T Khan, Charles L Kooperberg, Cathy C Laurie, X Shirley Liu, Michael C Mahaney, Ani W Manichaikul, Lisa Warsinger Martin, Rasika A Mathias, Stephen T McGarvey, Braxton D Mitchell, May E Montasser, Jill E Moore, Alanna C Morrison, Jeffrey R O'Connell, Nicholette D D Allred, Akhil Pampana, Juan M Peralta, Patricia A Peyser, Bruce M Psaty, Susan Redline, Kenneth M Rice, Stephen S Rich, Jennifer A Smith, Hemant K Tiwari, Michael Y Tsai, Ramachandran S Vasan, Fei Fei Wang, Daniel E Weeks, Nishigandha Phalke, James G Wilson, Lisa R Yanek, null null, null null, Benjamin M Neale, Shamil R Sunyaev, Gonçalo R Abecasis, Jerome I Rotter, Cristen J Willer, Gina M Peloso, Pradeep Natarajan, Xihong Lin
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nature genetics 52 (9) (2020)
Maria Kousi, Onuralp Söylemez, Aysegül Ozanturk, Niki Mourtzi, Sebastian Akle, Irwin Jungreis, Jean Muller, Christopher A Cassa, Harrison Brand, Jill Anne Rosenfeld, Maxim Y Wolf, Azita Sadeghpour, Kelsey McFadden, Richard A Lewis, Michael E Talkowski, Hélène Dollfus, Manolis Kellis, Erica E Davis, Shamil R Sunyaev, Nicholas Katsanis
Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy. Nature genetics 52 (11) (2020)
Felix Dietlein, Shamil R Sunyaev, Amaro Taylor-Weiner, André Richters, Brendan Reardon, David Liu, Eric S Lander, Eliezer Van Allen, Shamil R Sunyaev
Identification of cancer driver genes based on nucleotide context. Nature genetics 52 (2) (2020)
Mashaal Sohail, Robert M Maier, Andrea Ganna, Alex Bloemendal, Alicia R Martin, Michael C Turchin, Charleston W K Chiang, Joel Hirschhorn, Mark J Daly, Nick Patterson, Benjamin Neale, Iain Mathieson, David Reich, Shamil R Sunyaev
Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies. eLife 8 (2019)
Sahar Nissim, Ignaty Leshchiner, Joseph D Mancias, Matthew B Greenblatt, Ophélia Maertens, Christopher A Cassa, Jill A Rosenfeld, Andrew G Cox, John Hedgepeth, Julia I Wucherpfennig, Andrew J Kim, Jake E Henderson, Patrick Gonyo, Anthony C Brandt, Ellen Lorimer, Bethany Unger, Jeremy W Prokop, Jerry R Heidel, Xiao-Xu Wang, Chinedu I Ukaegbu, Benjamin C Jennings, Joao A Paulo, Sebastian Gableske, Carol A Fierke, Gad Getz, Shamil R Sunyaev, J Wade Harper, Karen Cichowski, Alec C Kimmelman, Yariv Houvras, Sapna Syngal, Carol Williams, Wolfram Goessling
Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nature genetics 51 (9) (2019)
Armin P Schoech, Daniel M Jordan, Po-Ru Loh, Steven Gazal, Luke O' Connor, Daniel J Balick, Pier Francesco Palamara, Hilary K Finucane, Shamil R Sunyaev, Alkes L Price
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection. Nature communications 10 (1) (2019)
Maha R Farhat, Luca Freschi, Roger Calderon, Thomas Ioerger, Matthew Snyder, Conor J Meehan, Bouke de Jong, Leen Rigouts, Alex Sloutsky, Devinder Kaur, Shamil R Sunyaev, Dick van Soolingen, Jay Shendure, Jim Sacchettini, Megan Murray
GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions. Nature communications 10 (1) (2019)
Christopher A Cassa, Shamil R Sunyaev, Daniel J Balick, Daniel M Jordan, David Nusinow, Kaitlin E Samocha, Anne O'Donnell-Luria, Daniel G MacArthur, Mark J Daly, David R Beier, Shamil R Sunyaev
Reply to 'Selective effects of heterozygous protein-truncating variants'. Nature genetics 51 (1) (2019)
Mashaal Sohail, Olga A Vakhrusheva, Jae Hoon Sul, Sara L Pulit, Laurent C Francioli, null null, null null, Leonard H van den Berg, Jan H Veldink, Paul I W de Bakker, Georgii A Bazykin, Alexey S Kondrashov, Shamil R Sunyaev
Negative selection in humans and fruit flies involves synergistic epistasis. Science (New York, N.Y.) 356 (6337) (2018)
Vladimir B Seplyarskiy, Evgeny E Akkuratov, Natalia Akkuratova, Maria A Andrianova, Sergey I Nikolaev, Georgii A Bazykin, Igor Adameyko, Shamil R Sunyaev
Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations. Nature genetics 51 (1) (2018)
Shamil R Sunyaev, Shamil R Sunyaev
Bayesian inference of negative and positive selection in human cancers. Nature genetics 49 (12) (2017)