Shirit Einav

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 18

Top Topics

Regulatory T Cells

Liquid Chromatography Tandem Mass Spectrometry

Top Venues

Journal of medicinal chemistry

Science translational medicine

Cellular and molecular life sciences : CMLS

This page only lists publications with an associated author ORCID identifier.

Publications

Michael Westberg, Yichi Su, Xinzhi Zou, Pinghan Huang, Arjun Rustagi, Jaishree Garhyan, Puja Bhavesh Patel, Daniel Fernández, Yan Wu, Chenzhou Hao, Chieh-Wen Lo, Marwah Karim, Lin Ning, Aimee Beck, Panatda Saenkham-Huntsinger, Vivian Tat, Aleksandra K Drelich, Bi-Hung Peng, Shirit Einav, Chien-Te Kent Tseng, Catherine A Blish, Michael Z Lin
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations. Science translational medicine 16 (738) (2024)
Michael Westberg, Yichi Su, Xinzhi Zou, Pinghan Huang, Arjun Rustagi, Jaishree Garhyan, Puja Bhavesh Patel, Daniel Fernández, Yan Wu, Chenzhou Hao, Chieh-Wen Lo, Marwah Karim, Lin Ning, Aimee Beck, Panatda Saenkham-Huntsinger, Vivian Tat, Aleksandra K Drelich, Bi-Hung Peng, Shirit Einav, Chien-Te Kent Tseng, Catherine A Blish, Michael Z Lin
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations. Science translational medicine 16 (738) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry 67 (15) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry (2024)
Michael Westberg, Yichi Su, Xinzhi Zou, Pinghan Huang, Arjun Rustagi, Jaishree Garhyan, Puja Bhavesh Patel, Daniel Fernández, Yan Wu, Chenzhou Hao, Chieh-Wen Lo, Marwah Karim, Lin Ning, Aimee Beck, Panatda Saenkham-Huntsinger, Vivian Tat, Aleksandra K Drelich, Bi-Hung Peng, Shirit Einav, Chien-Te Kent Tseng, Catherine A Blish, Michael Z Lin
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations. Science translational medicine 16 (738) (2024)
Michael Westberg, Yichi Su, Xinzhi Zou, Pinghan Huang, Arjun Rustagi, Jaishree Garhyan, Puja Bhavesh Patel, Daniel Fernández, Yan Wu, Chenzhou Hao, Chieh-Wen Lo, Marwah Karim, Lin Ning, Aimee Beck, Panatda Saenkham-Huntsinger, Vivian Tat, Aleksandra K Drelich, Bi-Hung Peng, Shirit Einav, Chien-Te Kent Tseng, Catherine A Blish, Michael Z Lin
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations. Science translational medicine 16 (738) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry 67 (15) (2024)
Michael Westberg, Yichi Su, Xinzhi Zou, Pinghan Huang, Arjun Rustagi, Jaishree Garhyan, Puja Bhavesh Patel, Daniel Fernández, Yan Wu, Chenzhou Hao, Chieh-Wen Lo, Marwah Karim, Lin Ning, Aimee Beck, Panatda Saenkham-Huntsinger, Vivian Tat, Aleksandra K Drelich, Bi-Hung Peng, Shirit Einav, Chien-Te Kent Tseng, Catherine A Blish, Michael Z Lin
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations. Science translational medicine 16 (738) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry (2024)
Luca Ghita, Zhiyuan Yao, Yike Xie, Veronica Duran, Halise Busra Cagirici, Jerome Samir, Ilham Osman, David Esteban Rebellón-Sánchez, Olga Lucia Agudelo-Rojas, Ana Maria Sanz, Malaya Kumar Sahoo, Makeda L Robinson, Rosa Margarita Gelvez-Ramirez, Nathalia Bueno, Fabio Luciani, Benjamin A Pinsky, Jose G Montoya, Maria Isabel Estupiñan-Cardenas, Luis Angel Villar-Centeno, Elsa Marina Rojas-Garrido, Fernando Rosso, Stephen R Quake, Fabio Zanini, Shirit Einav
Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach. Nature immunology (2023)
Makeda L Robinson, David R Glass, Veronica Duran, Olga Lucia Agudelo, Ana Maria Sanz, Monika Consuegra, Malaya Kumar Sahoo, Felix J Hartmann, Marc Bosse, Rosa Margarita Gelvez, Nathalia Bueno, Benjamin A Pinsky, Jose G Montoya, Holden Terry Maecker, María Isabel Estupiñán Cárdenas, Luis Angel Villar Centeno, Elsa Marina Rojas Garrido, Fernando Rosso, Sean C Bendall, Shirit Einav
Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics. Science advances 9 (12) (2023)
Zhiyuan Yao, Fabio Zanini, Sathish Kumar, Marwah Karim, Sirle Saul, Nishank Bhalla, Nuttada Panpradist, Avery Muniz, Aarthi Narayanan, Stephen R Quake, Shirit Einav
The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection. PLoS neglected tropical diseases 15 (3) (2021)
Sirle Saul, Shirit Einav
Old Drugs for a New Virus: Repurposed Approaches for Combating COVID-19. ACS infectious diseases 6 (9) (2020)
Natasha D Durham, Aditi Agrawal, Eric Waltari, Derek Croote, Fabio Zanini, Mallorie Fouch, Edgar Davidson, Olivia Smith, Esteban Carabajal, John E Pak, Benjamin J Doranz, Makeda Robinson, Ana M Sanz, Ludwig L Albornoz, Fernando Rosso, Shirit Einav, Stephen R Quake, Krista M McCutcheon, Leslie Goo
Broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics. eLife 8 (2019)
Sven Verdonck, Szu-Yuan Pu, Fiona J Sorrell, Jon M Elkins, Matheus Froeyen, Ling-Jie Gao, Laura I Prugar, Danielle E Dorosky, Jennifer M Brannan, Rina Barouch-Bentov, Stefan Knapp, John M Dye, Piet Herdwijn, Shirit Einav, Steven De Jonghe
Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity. Journal of medicinal chemistry 62 (12) (2019)
Fabio Zanini, Szu-Yuan Pu, Elena Bekerman, Shirit Einav, Stephen R Quake
Single-cell transcriptional dynamics of flavivirus infection. eLife 7 (2018)
Szu-Yuan Pu, Randy Wouters, Stanford Schor, Jef Rozenski, Rina Barouch-Bentov, Laura I Prugar, Cecilia M O'Brien, Jennifer M Brannan, John M Dye, Piet Herdwijn, Steven De Jonghe, Shirit Einav
Optimization of Isothiazolo[4,3- b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity. Journal of medicinal chemistry 61 (14) (2018)
Makeda Robinson, Stanford Schor, Rina Barouch-Bentov, Shirit Einav
Viral journeys on the intracellular highways. Cellular and molecular life sciences : CMLS 75 (20) (2018)