Andreas C Joerger

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 35

Top Venues

Journal of medicinal chemistry

ACS chemical biology

Cell death & disease

Oncogene

Albert-Ludwigs-Universität Freiburg

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Albert-Ludwigs-Universität Freiburg

Germany

Research Assistant :: Institute of Organic Chemistry and Biochemistry

Publications

Marcel Rak, Amelie Menge, Roberta Tesch, Lena M Berger, Dimitrios-Ilias Balourdas, Ekaterina Shevchenko, Andreas Krämer, Lewis Elson, Benedict-Tilmann Berger, Ismahan Abdi, Laurenz M Wahl, Antti Poso, Astrid Kaiser, Thomas Hanke, Thales Kronenberger, Andreas C Joerger, Susanne Müller, Stefan Knapp
Development of Selective Pyrido[2,3- d ]pyrimidin-7(8 H )-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors. Journal of medicinal chemistry 67 (5) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry 67 (15) (2024)
Marcel Rak, Amelie Menge, Roberta Tesch, Lena M Berger, Dimitrios-Ilias Balourdas, Ekaterina Shevchenko, Andreas Krämer, Lewis Elson, Benedict-Tilmann Berger, Ismahan Abdi, Laurenz M Wahl, Antti Poso, Astrid Kaiser, Thomas Hanke, Thales Kronenberger, Andreas C Joerger, Susanne Müller, Stefan Knapp
Development of Selective Pyrido[2,3- d ]pyrimidin-7(8 H )-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors. Journal of medicinal chemistry (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Dimitrios-Ilias Balourdas, Anja M Markl, Andreas Krämer, Giovanni Settanni, Andreas C Joerger
Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators. Cell death & disease 15 (6) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Dimitrios-Ilias Balourdas, Anja M Markl, Andreas Krämer, Giovanni Settanni, Andreas C Joerger
Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators. Cell death & disease 15 (6) (2024)
Dimitrios-Ilias Balourdas, Anja M Markl, Andreas Krämer, Giovanni Settanni, Andreas C Joerger
Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators. Cell death & disease 15 (6) (2024)
Marcel Rak, Amelie Menge, Roberta Tesch, Lena M Berger, Dimitrios-Ilias Balourdas, Ekaterina Shevchenko, Andreas Krämer, Lewis Elson, Benedict-Tilmann Berger, Ismahan Abdi, Laurenz M Wahl, Antti Poso, Astrid Kaiser, Thomas Hanke, Thales Kronenberger, Andreas C Joerger, Susanne Müller, Stefan Knapp
Development of Selective Pyrido[2,3- d ]pyrimidin-7(8 H )-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors. Journal of medicinal chemistry 67 (5) (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Dimitrios-Ilias Balourdas, Anja M Markl, Andreas Krämer, Giovanni Settanni, Andreas C Joerger
Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators. Cell death & disease 15 (6) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry 67 (15) (2024)
Nicolas Bauer, Dimitrios-Ilias Balourdas, Joel R Schneider, Xin Zhang, Lena Marie Berger, Benedict-Tilmann Berger, Martin Peter Schwalm, Nick A Klopp, Jens T Siveke, Stefan Knapp, Andreas C Joerger
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. ACS chemical biology 19 (2) (2024)
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C Joerger, Christian Schreiber, Lena Marie Berger, Benedict-Tilmann Berger, Theresa A L Ehret, Lewis Elson, Christopher Lenz, Krishna Saxena, Susanne Müller, Shirit Einav, Stefan Knapp, Thomas Hanke
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors. Journal of medicinal chemistry (2024)
Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, Andreas C Joerger, Amelie Menge, Andreas Krämer, Julia Marie Frischkorn, Benedict-Tilmann Berger, Lewis Elson, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of medicinal chemistry (2023)
Xiaomin Ni, Andreas C Joerger, Apirat Chaikuad, Stefan Knapp
Structural insights into a regulatory mechanism of FIR RRM1-FUSE interaction. Open biology 13 (5) (2023)
Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, Andreas C Joerger, Amelie Menge, Andreas Krämer, Julia Marie Frischkorn, Benedict-Tilmann Berger, Lewis Elson, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of medicinal chemistry 67 (1) (2023)
Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, Andreas C Joerger, Amelie Menge, Andreas Krämer, Julia Marie Frischkorn, Benedict-Tilmann Berger, Lewis Elson, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of medicinal chemistry 67 (1) (2023)
Maëva M Pichon, Dawid Drelinkiewicz, David Lozano, Ruxandra Moraru, Laura J Hayward, Megan Jones, Michael A McCoy, Samuel Allstrum-Graves, Dimitrios-Ilias Balourdas, Andreas C Joerger, Richard J Whitby, Stephen Michael Goldup, Neil Wells, Graham J Langley, Julie M Herniman, Matthias G J Baud
Structure-Reactivity Studies of 2-Sulfonylpyrimidines Allow Selective Protein Arylation. Bioconjugate chemistry (2023)
Jennifer Alisa Amrhein, Lena Marie Berger, Dimitrios-Ilias Balourdas, Andreas C Joerger, Amelie Menge, Andreas Krämer, Julia Marie Frischkorn, Benedict-Tilmann Berger, Lewis Elson, Astrid Kaiser, Manfred Schubert-Zsilavecz, Susanne Müller, Stefan Knapp, Thomas Hanke
Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3. Journal of medicinal chemistry 67 (1) (2023)
Javier R Balboa, Dominik J Essig, Sana Ma, Nichlas Karer, Louise S Clemmensen, Søren W Pedersen, Andreas C Joerger, Stefan Knapp, Søren Østergaard, Kristian Stro Mgaard
Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction. Journal of medicinal chemistry (2022)
Javier R Balboa, Dominik J Essig, Sana Ma, Nichlas Karer, Louise S Clemmensen, Søren W Pedersen, Andreas C Joerger, Stefan Knapp, Søren Østergaard, Kristian Stro Mgaard
Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction. Journal of medicinal chemistry 66 (1) (2022)
Qiang Zhang, Dimitrios-Ilias Balourdas, Bruno Baron, Alon Senitzki, Tali E Haran, Klas G Wiman, Thierry Soussi, Andreas C Joerger
Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog. Cell death & disease 13 (3) (2022)
Javier R Balboa, Dominik J Essig, Sana Ma, Nichlas Karer, Louise S Clemmensen, Søren W Pedersen, Andreas C Joerger, Stefan Knapp, Søren Østergaard, Kristian Stro Mgaard
Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction. Journal of medicinal chemistry 66 (1) (2022)
Joseph R Stephenson Clarke, Leon R Douglas, Patrick J Duriez, Dimitrios-Ilias Balourdas, Andreas C Joerger, Raniya Khadiullina, Emil Bulatov, Matthias G J Baud
Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C. ACS pharmacology & translational science 5 (11) (2022)
Javier R Balboa, Dominik J Essig, Sana Ma, Nichlas Karer, Louise S Clemmensen, Søren W Pedersen, Andreas C Joerger, Stefan Knapp, Søren Østergaard, Kristian Stro Mgaard
Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction. Journal of medicinal chemistry 66 (1) (2022)
Roberta Tesch, Marcel Rak, Monika Raab, Lena Marie Berger, Thales Kronenberger, Andreas C Joerger, Benedict-Tilmann Berger, Ismahan Abdi, Thomas Hanke, Antti Poso, Klaus Strebhardt, Mourad Sanhaji, Stefan Knapp
Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors. Journal of medicinal chemistry 64 (12) (2021)
Marek Wanior, Andreas Krämer, Stefan Knapp, Andreas C Joerger
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy. Oncogene 40 (21) (2021)
Sandra Röhm, Benedict-Tilmann Berger, Martin Schröder, Deep Chatterjee, Sebastian Mathea, Andreas C Joerger, Daniel M Pinkas, Joshua C Bufton, Amelie Tjaden, Lohitesh Kovooru, Mark Kudolo, Christian Pohl, Alex N Bullock, Susanne Müller, Stefan A Laufer, Stefan Knapp
Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe. Journal of medicinal chemistry 64 (18) (2021)
Matthias R Bauer, Andreas Krämer, Giovanni Settanni, Rhiannon N Jones, Xiaomin Ni, Raysa Khan Tareque, Alan R Fersht, John Spencer, Andreas C Joerger
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm. ACS chemical biology 15 (3) (2020)
Marek Wanior, Franziska Preuss, Xiaomin Ni, Andreas Krämer, Sebastian Mathea, Tamara Göbel, David Heidenreich, Svenja Simonyi, Astrid S Kahnt, Andreas C Joerger, Stefan Knapp
Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. Journal of medicinal chemistry 63 (23) (2020)
Matthias R Bauer, Rhiannon N Jones, Raysa K Tareque, Bradley Springett, Felix A Dingler, Lorena Verduci, Ketan J Patel, Alan R Fersht, Andreas C Joerger, John Spencer
A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C. Future medicinal chemistry 11 (19) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Andreas C Joerger