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Timothy G Palzkill (Timothy Palzkill)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 32

Top Venues

Communications biology

Science advances

Antimicrobial agents and chemotherapy

Physical chemistry chemical physics : PCCP

This page only lists publications with an associated author ORCID identifier.

Publications

Allison K Judge, Liya Hu, Banumathi Sankaran, Justin Van Riper, B V Venkataram Prasad, Timothy G Palzkill
Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase. Communications biology 6 (1) (2023)
Lynn Su, Wanzhi Huang, Frederick H Neill, Mary K Estes, Robert L Atmar, Timothy G Palzkill
Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response. NPJ vaccines 8 (1) (2023)
Seyed Arad Moghadasi, Emmanuel Heilmann, Ahmed Magdy Khalil, Christina Nnabuife, Fiona L Kearns, Chengjin Ye, Sofia N Moraes, Francesco Costacurta, Morgan A Esler, Hideki Aihara, Dorothee von Laer, Luis Martinez-Sobrido, Timothy G Palzkill, Rommie Elizabeth Amaro, Reuben Stewart Harris
Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors. Science advances 9 (13) (2023)
Seyed Arad Moghadasi, Emmanuel Heilmann, Ahmed Magdy Khalil, Christina Nnabuife, Fiona L Kearns, Chengjin Ye, Sofia N Moraes, Francesco Costacurta, Morgan A Esler, Hideki Aihara, Dorothee von Laer, Luis Martinez-Sobrido, Timothy G Palzkill, Rommie Elizabeth Amaro, Reuben Stewart Harris
Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors. Science advances 9 (13) (2023)
Allison K Judge, Liya Hu, Banumathi Sankaran, Justin Van Riper, B V Venkataram Prasad, Timothy G Palzkill
Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase. Communications biology 6 (1) (2023)
Chao Yin, Zilin Song, Hao Tian, Timothy G Palzkill, Peng Tao
Unveiling the structural features that regulate carbapenem deacylation in KPC-2 through QM/MM and interpretable machine learning. Physical chemistry chemical physics : PCCP 25 (2) (2023)
Ravikumar Jimmidi, Srinivas Chamakuri, Shuo Lu, Melek Nihan Ucisik, Peng-Jen Chen, Kurt M Bohren, Seyed Arad Moghadasi, Leroy Versteeg, Christina Nnabuife, Jian-Yuan Li, Xuan Qin, Ying-Chu Chen, John C Faver, Pranavanand Nyshadham, Kiran L Sharma, Banumathi Sankaran, Allison K Judge, Zhifeng Yu, Feng Li, Jeroen Pollet, Reuben S Harris, Martin M Matzuk, Timothy G Palzkill, Damian W Young
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors. Communications chemistry 6 (1) (2023)
Chao Yin, Zilin Song, Hao Tian, Timothy G Palzkill, Peng Tao
Unveiling the structural features that regulate carbapenem deacylation in KPC-2 through QM/MM and interpretable machine learning. Physical chemistry chemical physics : PCCP 25 (2) (2023)
Allison K Judge, Liya Hu, Banumathi Sankaran, Justin Van Riper, B V Venkataram Prasad, Timothy G Palzkill
Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase. Communications biology 6 (1) (2023)
Allison K Judge, Liya Hu, Banumathi Sankaran, Justin Van Riper, B V Venkataram Prasad, Timothy G Palzkill
Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase. Communications biology 6 (1) (2023)
Seyed Arad Moghadasi, Emmanuel Heilmann, Ahmed Magdy Khalil, Christina Nnabuife, Fiona L Kearns, Chengjin Ye, Sofia N Moraes, Francesco Costacurta, Morgan A Esler, Hideki Aihara, Dorothee von Laer, Luis Martinez-Sobrido, Timothy G Palzkill, Rommie Elizabeth Amaro, Reuben Stewart Harris
Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors. Science advances 9 (13) (2023)
Allison K Judge, Liya Hu, Banumathi Sankaran, Justin Van Riper, B V Venkataram Prasad, Timothy G Palzkill
Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M β-lactamase. Communications biology 6 (1) (2023)
Chao Yin, Zilin Song, Hao Tian, Timothy G Palzkill, Peng Tao
Unveiling the structural features that regulate carbapenem deacylation in KPC-2 through QM/MM and interpretable machine learning. Physical chemistry chemical physics : PCCP (2022)
Shuo Lu, Liya Hu, Hanfeng Lin, Allison K Judge, Paola Rivera, Murugesan Palaniappan, Banumathi Sankaran, Jin Wang, B V Venkataram Prasad, Timothy G Palzkill
An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M β-lactamase drug-resistance enzymes. Nature communications 13 (1) (2022)
Zhizeng Sun, Lynn Su, Nicole Cotroneo, Ian Critchley, Michael Pucci, Akash Jain, Timothy G Palzkill
Evaluation of Tebipenem Hydrolysis by β-Lactamases Prevalent in Complicated Urinary Tract Infections. Antimicrobial agents and chemotherapy 66 (5) (2022)
Patricia A Bradford, Robert A Bonomo, Karen Bush, Alessandra Carattoli, Michael Feldgarden, Daniel H Haft, Yoshikazu Ishii, George A Jacoby, William Klimke, Timothy G Palzkill, Laurent Poirel, Gian Maria Rossolini, Pranita D Tamma, César A Arias
Consensus on β-Lactamase Nomenclature. Antimicrobial agents and chemotherapy 66 (4) (2022)
Doris Mia Taylor, Justin Anglin, Liya Hu, Lingfei Wang, Banumathi Sankaran, Jin Wang, Martin M Matzuk, B V Venkataram Prasad, Timothy G Palzkill
Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48. ACS infectious diseases 7 (12) (2021)
Vlatko Stojanoski, Liya Hu, Banumathi Sankaran, Feng Wang, Peng Tao, B V Venkataram Prasad, Timothy G Palzkill
Mechanistic Basis of OXA-48-like β-Lactamases' Hydrolysis of Carbapenems. ACS infectious diseases 7 (2) (2021)
David M Boragine, Wanzhi Huang, Lynn H Su, Timothy G Palzkill
Deep Sequencing of a Systematic Peptide Library Reveals Conformationally-Constrained Protein Interface Peptides that Disrupt a Protein-Protein Interaction. Chembiochem : a European journal of chemical biology (2021)
Zhizeng Sun, Timothy G Palzkill
Deep Mutational Scanning Reveals the Active-Site Sequence Requirements for the Colistin Antibiotic Resistance Enzyme MCR-1. mBio (2021)
Sandra Rincon, Lina P Carvajal, Sara I Gomez-Villegas, Aura M Echeverri, Rafael Rios, An Dinh, Claudia Pedroza, Karen M Ordoñez, Esteban Nannini, Zhizeng Sun, Vance G Fowler, Barbara E Murray, William R Miller, Timothy G Palzkill, Lorena Diaz, Cesar A Arias, Jinnethe Reyes
A Test for the Rapid Detection of the Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus. Journal of clinical microbiology 59 (4) (2021)
James M Musser, Stephen B Beres, Luchang Zhu, Randall J Olsen, Jaana Vuopio, Hanne-Leena Hyyryläinen, Kirsi Gröndahl-Yli-Hannuksela, Karl G Kristinsson, Jessica Darenberg, Birgitta Henriques-Normark, Steen Hoffmann, Dominque A Caugant, Andrew J Smith, Diane S J Lindsay, David M Boragine, Timothy G Palzkill
Reduced In Vitro Susceptibility of Streptococcus pyogenes to β-Lactam Antibiotics Associated with Mutations in the pbp2x Gene Is Geographically Widespread. Journal of clinical microbiology 58 (4) (2020)
Shuo Lu, Victoria Soeung, Hoang A T Nguyen, Scott Wesley Long, James M Musser, Timothy G Palzkill
Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC β-Lactamases from Klebsiella pneumoniae Clinical Isolates. mSphere 5 (1) (2020)
Andrew R Mack, Melissa D Barnes, Magdalena A Taracila, Andrea M Hujer, Kristine M Hujer, Gabriel Cabot, Michael Feldgarden, Daniel H Haft, William Klimke, Focco van den Akker, Alejandro J Vila, Andrea Smania, Shozeb Haider, Krisztina M Papp-Wallace, Patricia A Bradford, Gian Maria Rossolini, Jean-Denis Docquier, Jean-Marie Frère, Moreno Galleni, Nancy D Hanson, Antonio Oliver, Patrick Plésiat, Laurent Poirel, Patrice Nordmann, Timothy G Palzkill, George A Jacoby, Karen Bush, Robert A Bonomo
A Standard Numbering Scheme for Class C β-Lactamases. Antimicrobial agents and chemotherapy 64 (3) (2020)
Doris Mia Taylor, Justin Anglin, Suhyeorn Park, Melek N Ucisik, John C Faver, Nicholas Simmons, Zhuang Jin, Murugesan Palaniappan, Pranavanand Nyshadham, Feng Li, James Campbell, Liya Hu, Banumathi Sankaran, B V Venkataram Prasad, Hongbing Huang, Martin M Matzuk, Timothy G Palzkill
Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries. ACS infectious diseases 6 (5) (2020)
Wanzhi Huang, Victoria Soeung, David M Boragine, Timothy G Palzkill
Mapping Protein-Protein Interaction Interface Peptides with Jun-Fos Assisted Phage Display and Deep Sequencing. ACS synthetic biology 9 (7) (2020)
Wanzhi Huang, Victoria Soeung, David M Boragine, Liya Hu, B V Venkataram Prasad, Mary K Estes, Robert L Atmar, Timothy G Palzkill
High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing. Journal of virology 95 (1) (2020)
Jianwei Chen, Xiqian Jiang, Chengwei Zhang, Kevin R MacKenzie, Fabio Stossi, Timothy G Palzkill, Meng C Wang, Jin Wang
Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria. ACS sensors 2 (9) (2017)
Meha P Patel, Liya Hu, Vlatko Stojanoski, Banumathi Sankaran, B V Venkataram Prasad, Timothy G Palzkill
The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation. Biochemistry 56 (27) (2017)
Carolyn J Adamski, Timothy G Palzkill
BLIP-II Employs Differential Hotspot Residues To Bind Structurally Similar Staphylococcus aureus PBP2a and Class A β-Lactamases. Biochemistry 56 (8) (2017)
Carolyn J Adamski, Timothy G Palzkill
Systematic substitutions at BLIP position 50 result in changes in binding specificity for class A β-lactamases. BMC biochemistry 18 (1) (2017)
Vlatko Stojanoski, Banumathi Sankaran, B V Venkataram Prasad, Laurent Poirel, Patrice Nordmann, Timothy G Palzkill
Structure of the catalytic domain of the colistin resistance enzyme MCR-1. BMC biology 14 (1) (2016)

Timothy G Palzkill.css-eqlu8i{font-size:small;padding-left:4px;} (Timothy Palzkill)

Publication Activity (10 Years)

Top Topics

Top Venues

Timothy G Palzkill (Timothy Palzkill)