Brenda A Schulman (Brenda Schulman)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 72

Top Venues

Nature structural & molecular biology

Nature communications

bioRxiv : the preprint server for biology

Nature cell biology

Max-Planck-Institut für Biochemie

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Max-Planck-Institut für Biochemie

Germany

Director :: Molecular Machines and Signaling

Publications

J Josephine Botsch, Roswitha Junker, Michèle Sorgenfrei, Patricia P Ogger, Luca Stier, Susanne von Gronau, Peter J Murray, Markus A Seeger, Brenda A Schulman, Bastian Bräuning
Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE. Nature communications 15 (1) (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology 31 (2) (2024)
Melissa J Hoyer, Cristina Capitanio, Ian R Smith, Julia C Paoli, Anna Bieber, Yizhi Jiang, Joao A Paulo, Miguel A Gonzalez-Lozano, Wolfgang Baumeister, Florian Wilfling, Brenda A Schulman, J Wade Harper
Combinatorial selective ER-phagy remodels the ER during neurogenesis. Nature cell biology 26 (3) (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology 31 (2) (2024)
Melissa J Hoyer, Cristina Capitanio, Ian R Smith, Julia C Paoli, Anna Bieber, Yizhi Jiang, Joao A Paulo, Miguel A Gonzalez-Lozano, Wolfgang Baumeister, Florian Wilfling, Brenda A Schulman, J Wade Harper
Combinatorial selective ER-phagy remodels the ER during neurogenesis. Nature cell biology 26 (3) (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology 31 (2) (2024)
Felix Kraus, Yuchen He, Sharan Swarup, Katherine A Overmyer, Yizhi Jiang, Johann Brenner, Cristina Capitanio, Anna Bieber, Annie Jen, Nicole M Nightingale, Benton J Anderson, Chan Lee, Joao A Paulo, Ian R Smith, Jürgen M Plitzko, Brenda A Schulman, Florian Wilfling, Joshua J Coon, J Wade Harper
Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2. bioRxiv : the preprint server for biology (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. bioRxiv : the preprint server for biology (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nature structural & molecular biology (2024)
J Josephine Botsch, Roswitha Junker, Michèle Sorgenfrei, Patricia P Ogger, Luca Stier, Susanne von Gronau, Peter J Murray, Markus A Seeger, Brenda A Schulman, Bastian Bräuning
Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE. Nature communications 15 (1) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology 31 (2) (2024)
Daniel Horn-Ghetko, Linus V M Hopf, Ishita Tripathi-Giesgen, Jiale Du, Sebastian Kostrhon, D Tung Vu, Viola Beier, Barbara Steigenberger, J Rajan Prabu, Luca Stier, Elias M Bruss, Matthias Mann, Yue Xiong, Brenda A Schulman
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature structural & molecular biology 31 (7) (2024)
Melissa J Hoyer, Cristina Capitanio, Ian R Smith, Julia C Paoli, Anna Bieber, Yizhi Jiang, Joao A Paulo, Miguel A Gonzalez-Lozano, Wolfgang Baumeister, Florian Wilfling, Brenda A Schulman, J Wade Harper
Combinatorial selective ER-phagy remodels the ER during neurogenesis. Nature cell biology (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nature structural & molecular biology (2024)
Daniel Horn-Ghetko, Linus V M Hopf, Ishita Tripathi-Giesgen, Jiale Du, Sebastian Kostrhon, D Tung Vu, Viola Beier, Barbara Steigenberger, J Rajan Prabu, Luca Stier, Elias M Bruss, Matthias Mann, Yue Xiong, Brenda A Schulman
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature structural & molecular biology 31 (7) (2024)
Daniel Horn-Ghetko, Linus V M Hopf, Ishita Tripathi-Giesgen, Jiale Du, Sebastian Kostrhon, D Tung Vu, Viola Beier, Barbara Steigenberger, J Rajan Prabu, Luca Stier, Elias M Bruss, Matthias Mann, Yue Xiong, Brenda A Schulman
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature structural & molecular biology (2024)
Daniel Horn-Ghetko, Linus V M Hopf, Ishita Tripathi-Giesgen, Jiale Du, Sebastian Kostrhon, D Tung Vu, Viola Beier, Barbara Steigenberger, J Rajan Prabu, Luca Stier, Elias M Bruss, Matthias Mann, Yue Xiong, Brenda A Schulman
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature structural & molecular biology 31 (7) (2024)
J Josephine Botsch, Roswitha Junker, Michèle Sorgenfrei, Patricia P Ogger, Luca Stier, Susanne von Gronau, Peter J Murray, Markus A Seeger, Brenda A Schulman, Bastian Bräuning
Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE. Nature communications 15 (1) (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. bioRxiv : the preprint server for biology (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. bioRxiv : the preprint server for biology (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology 31 (2) (2024)
Daniel Horn-Ghetko, Linus V M Hopf, Ishita Tripathi-Giesgen, Jiale Du, Sebastian Kostrhon, D Tung Vu, Viola Beier, Barbara Steigenberger, J Rajan Prabu, Luca Stier, Elias M Bruss, Matthias Mann, Yue Xiong, Brenda A Schulman
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature structural & molecular biology 31 (7) (2024)
Melissa J Hoyer, Cristina Capitanio, Ian R Smith, Julia C Paoli, Anna Bieber, Yizhi Jiang, Joao A Paulo, Miguel A Gonzalez-Lozano, Wolfgang Baumeister, Florian Wilfling, Brenda A Schulman, J Wade Harper
Combinatorial selective ER-phagy remodels the ER during neurogenesis. Nature cell biology 26 (3) (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nature structural & molecular biology (2024)
Melissa J Hoyer, Cristina Capitanio, Ian R Smith, Julia C Paoli, Anna Bieber, Yizhi Jiang, Joao A Paulo, Miguel A Gonzalez-Lozano, Wolfgang Baumeister, Florian Wilfling, Brenda A Schulman, J Wade Harper
Combinatorial selective ER-phagy remodels the ER during neurogenesis. Nature cell biology 26 (3) (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. bioRxiv : the preprint server for biology (2024)
Melissa J Hoyer, Cristina Capitanio, Ian R Smith, Julia C Paoli, Anna Bieber, Yizhi Jiang, Joao A Paulo, Miguel A Gonzalez-Lozano, Wolfgang Baumeister, Florian Wilfling, Brenda A Schulman, J Wade Harper
Combinatorial selective ER-phagy remodels the ER during neurogenesis. Nature cell biology (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology 31 (2) (2024)
Felix Kraus, Yuchen He, Sharan Swarup, Katherine A Overmyer, Yizhi Jiang, Johann Brenner, Cristina Capitanio, Anna Bieber, Annie Jen, Nicole M Nightingale, Benton J Anderson, Chan Lee, Joao A Paulo, Ian R Smith, Jürgen M Plitzko, Brenda A Schulman, Florian Wilfling, Joshua J Coon, J Wade Harper
Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2. bioRxiv : the preprint server for biology (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nature structural & molecular biology 31 (8) (2024)
Felix Kraus, Yuchen He, Sharan Swarup, Katherine A Overmyer, Yizhi Jiang, Johann Brenner, Cristina Capitanio, Anna Bieber, Annie Jen, Nicole M Nightingale, Benton J Anderson, Chan Lee, Joao A Paulo, Ian R Smith, Jürgen M Plitzko, Brenda A Schulman, Florian Wilfling, Joshua J Coon, J Wade Harper
Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2. bioRxiv : the preprint server for biology (2024)
Daniel Horn-Ghetko, Linus V M Hopf, Ishita Tripathi-Giesgen, Jiale Du, Sebastian Kostrhon, D Tung Vu, Viola Beier, Barbara Steigenberger, J Rajan Prabu, Luca Stier, Elias M Bruss, Matthias Mann, Yue Xiong, Brenda A Schulman
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nature structural & molecular biology 31 (7) (2024)
Joanna Liwocha, Jerry Li, Nicholas Purser, Chutima Rattanasopa, Samuel Maiwald, David T Krist, Daniel C Scott, Barbara Steigenberger, J Rajan Prabu, Brenda A Schulman, Gary Kleiger
Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nature structural & molecular biology 31 (2) (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nature structural & molecular biology 31 (8) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Frank Adolf, Jiale Du, Ellen A Goodall, Richard M Walsh, Shaun Rawson, Susanne von Gronau, J Wade Harper, John Hanna, Brenda A Schulman
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nature structural & molecular biology 31 (8) (2024)
Melissa J Hoyer, Cristina Capitanio, Ian R Smith, Julia C Paoli, Anna Bieber, Yizhi Jiang, Joao A Paulo, Miguel A Gonzalez-Lozano, Wolfgang Baumeister, Florian Wilfling, Brenda A Schulman, J Wade Harper
Combinatorial selective ER-phagy remodels the ER during neurogenesis. Nature cell biology 26 (3) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Felix Kraus, Yuchen He, Sharan Swarup, Katherine A Overmyer, Yizhi Jiang, Johann Brenner, Cristina Capitanio, Anna Bieber, Annie Jen, Nicole M Nightingale, Benton J Anderson, Chan Lee, Joao A Paulo, Ian R Smith, Jürgen M Plitzko, Brenda A Schulman, Florian Wilfling, Joshua J Coon, J Wade Harper
Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2. bioRxiv : the preprint server for biology (2024)
Meijing Li, Ishita Tripathi-Giesgen, Brenda A Schulman, Wolfgang Baumeister, Florian Wilfling
In situ snapshots along a mammalian selective autophagy pathway. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Iona Wallace, Kheewoong Baek, J Rajan Prabu, Ronnald Vollrath, Susanne von Gronau, Brenda A Schulman, Kirby N Swatek
Insights into the ISG15 transfer cascade by the UBE1L activating enzyme. Nature communications 14 (1) (2023)
Meijing Li, Ishita Tripathi-Giesgen, Brenda A Schulman, Wolfgang Baumeister, Florian Wilfling
In situ snapshots along a mammalian selective autophagy pathway. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Felix Kraus, Ellen A Goodall, Ian R Smith, Yizhi Jiang, Julia C Paoli, Frank Adolf, Jiuchun Zhang, Joao A Paulo, Brenda A Schulman, J Wade Harper
PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems. EMBO reports (2023)
Lukas T Henneberg, Jaspal Singh, David M Duda, Kheewoong Baek, David Yanishevski, Peter J Murray, Matthias Mann, Sachdev S Sidhu, Brenda A Schulman
Activity-based profiling of cullin-RING ligase networks by conformation-specific probes. bioRxiv : the preprint server for biology (2023)
Lukas T Henneberg, Jaspal Singh, David M Duda, Kheewoong Baek, David Yanishevski, Peter J Murray, Matthias Mann, Sachdev S Sidhu, Brenda A Schulman
Activity-based profiling of cullin-RING ligase networks by conformation-specific probes. bioRxiv : the preprint server for biology (2023)
Lukas T Henneberg, Jaspal Singh, David M Duda, Kheewoong Baek, David Yanishevski, Peter J Murray, Matthias Mann, Sachdev S Sidhu, Brenda A Schulman
Activity-based profiling of cullin-RING E3 networks by conformation-specific probes. Nature chemical biology (2023)
Alexis González, Adriana Covarrubias-Pinto, Ramachandra M Bhaskara, Marius Glogger, Santosh Kumar Kuncha, Audrey Xavier, Eric Seemann, Mohit Misra, Marina E Hoffmann, Bastian Bräuning, Ashwin Balakrishnan, Britta Qualmann, Volker Dötsch, Brenda A Schulman, Michael Manfred Kessels, Christian A Hübner, Mike Heilemann, Gerhard Hummer, Ivan Đikić
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum. Nature (2023)
Meijing Li, Ishita Tripathi-Giesgen, Brenda A Schulman, Wolfgang Baumeister, Florian Wilfling
In situ snapshots along a mammalian selective autophagy pathway. Proceedings of the National Academy of Sciences of the United States of America 120 (12) (2023)
Christine R Langlois, Viola Beier, Özge Karayel, Jakub Chrustowicz, Dawafuti Sherpa, Matthias Mann, Brenda A Schulman
A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters. EMBO reports 23 (6) (2022)
Dawafuti Sherpa, Judith Mueller, Özge Karayel, Peng Xu, Yu Yao, Jakub Chrustowicz, Karthik V Gottemukkala, Christine Baumann, Annette Gross, Oliver Czarnecki, Wei Zhang, Jun Gu, Johan Nilvebrant, Sachdev S Sidhu, Peter J Murray, Matthias Mann, Mitchell J Weiss, Brenda A Schulman, Arno F Alpi
Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation. eLife 11 (2022)
Anna Bieber, Cristina Capitanio, Philipp S Erdmann, Fabian Fiedler, Florian Beck, Chia-Wei Lee, Delong Li, Gerhard Hummer, Brenda A Schulman, Wolfgang Baumeister, Florian Wilfling
In situ structural analysis reveals membrane shape transitions during autophagosome formation. Proceedings of the National Academy of Sciences of the United States of America 119 (39) (2022)
Shuai Qiao, Chia-Wei Lee, Dawafuti Sherpa, Jakub Chrustowicz, Jingdong Cheng, Maximilian Duennebacke, Barbara Steigenberger, Özge Karayel, Duc Tung Vu, Susanne von Gronau, Matthias Mann, Florian Wilfling, Brenda A Schulman
Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nature communications 13 (1) (2022)
Linus V M Hopf, Kheewoong Baek, Maren Klügel, Susanne von Gronau, Yue Xiong, Brenda A Schulman
Structure of CRL7 FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation. Nature structural & molecular biology 29 (9) (2022)
Ivan Đikić, Brenda A Schulman
An expanded lexicon for the ubiquitin code. Nature reviews. Molecular cell biology (2022)
Özge Karayel, Peng Xu, Isabell Bludau, Senthil Velan Bhoopalan, Yu Yao, Freitas Colaco Ana Rita, Alberto Santos, Brenda A Schulman, Arno F Alpi, Mitchell J Weiss, Matthias Mann
Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis. Molecular systems biology 16 (12) (2021)
Lukas Pluska, Ernst Jarosch, Henrik Zauber, Andreas Kniss, Anita Waltho, Katrin Bagola, Maximilian von Delbrück, Frank Löhr, Brenda A Schulman, Matthias Selbach, Volker Dötsch, Thomas Sommer
The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63-branched ubiquitin chains. The EMBO journal 40 (6) (2021)
Sebastian Kostrhon, J Rajan Prabu, Kheewoong Baek, Daniel Horn-Ghetko, Susanne von Gronau, Maren Klügel, Jérôme Basquin, Arno F Alpi, Brenda A Schulman
CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation. Nature chemical biology 17 (10) (2021)
Daniel Horn-Ghetko, David T Krist, J Rajan Prabu, Kheewoong Baek, Monique P C Mulder, Maren Klügel, Daniel C Scott, Huib Ovaa, Gary Kleiger, Brenda A Schulman
Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature 590 (7847) (2021)
Fynn M Hansen, Maria C Tanzer, Franziska Brüning, Isabell Bludau, Che Stafford, Brenda A Schulman, Maria S Robles, Özge Karayel, Matthias Mann
Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology. Nature communications 12 (1) (2021)
Adar Sonn-Segev, Katarina Belačić, Tatyana Bodrug, Gavin Young, Ryan T VanderLinden, Brenda A Schulman, Johannes Schimpf, Thorsten Friedrich, Phat Vinh Dip, Thomas U Schwartz, Benedikt Bauer, Jan-Michael Peters, Weston B Struwe, Justin L P Benesch, Nicholas G Brown, David Haselbach, Philipp Kukura
Quantifying the heterogeneity of macromolecular machines by mass photometry. Nature communications 11 (1) (2020)
Kheewoong Baek, Brenda A Schulman
Molecular glue concept solidifies. Nature chemical biology 16 (1) (2020)
Donghyuk Shin, Rukmini Mukherjee, Diana Grewe, Denisa Bojkova, Kheewoong Baek, Anshu Bhattacharya, Laura Schulz, Marek Widera, Ahmad Reza Mehdipour, Georg Tascher, Paul P Geurink, Alexander Wilhelm, Gerbrand J van der Heden van Noort, Huib Ovaa, Stefan Müller, Klaus-Peter Knobeloch, Krishnaraj Rajalingam, Brenda A Schulman, Jindrich Cinatl, Gerhard Hummer, Sandra Ciesek, Ivan Đikić
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature 587 (7835) (2020)
Lakshmi E Miller-Vedam, Bastian Bräuning, Katerina D Popova, Nicole T Schirle Oakdale, Jessica L Bonnar, Jesuraj R Prabu, Elizabeth A Boydston, Natalia Sevillano, Matthew J Shurtleff, Robert M Stroud, Charles S Craik, Brenda A Schulman, Adam Frost, Jonathan S Weissman
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. eLife 9 (2020)
Joanna Liwocha, David T Krist, Gerbrand J van der Heden van Noort, Fynn M Hansen, Vinh H Truong, Ozge Karayel, Nicholas Purser, Daniel Houston, Nicole Burton, Mark J Bostock, Michael Sattler, Matthias Mann, Joseph S Harrison, Gary Kleiger, Huib Ovaa, Brenda A Schulman
Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler. Nature chemical biology 17 (3) (2020)
Özge Karayel, André C Michaelis, Matthias Mann, Brenda A Schulman, Christine R Langlois
DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift. Proceedings of the National Academy of Sciences of the United States of America 117 (51) (2020)
Katherine V Richeson, Tatyana Bodrug, Katharine L Sackton, Masaya Yamaguchi, Joao A Paulo, Steven P Gygi, Brenda A Schulman, Nicholas G Brown, Randall W King
Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20. Nature chemical biology 16 (5) (2020)
Yumei Zheng, Yu Qiu, Christy R R Grace, Xu Liu, Daniel J Klionsky, Brenda A Schulman
A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade. Nature communications 10 (1) (2019)
Yu Qiu, Yumei Zheng, Christy R R Grace, Xu Liu, Daniel J Klionsky, Brenda A Schulman
Allosteric regulation through a switch element in the autophagy E2, Atg3. Autophagy 16 (1) (2019)

Brenda A Schulman.css-eqlu8i{font-size:small;padding-left:4px;} (Brenda Schulman)

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Brenda A Schulman (Brenda Schulman)