Martin Jinek (M Jinek)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 47

Top Venues

Nature communications

Science (New York, N.Y.)

eLife

Nucleic acids research

University of Zurich

European Molecular Biology Laboratory (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Zurich Apr 01 2018

Switzerland

Associate Professor :: Department of Biochemistry

University of Zurich Feb 01 2013 - Mar 31 2018

Switzerland

Assistant Professor :: Department of Biochemistry

Education History

European Molecular Biology Laboratory Sep 01 2002 - Dec 31 2006

Germany

PHD

Publications

Giordano Reginato, Maria Rosaria Dello Stritto, Yanbo Wang, Jingzhou Hao, Raphael S Pavani, Michael Schmitz, Swagata Halder, Vincent Morin, Elda Cannavo, Ilaria Ceppi, Stefan Braunshier, Ananya Acharya, Virginie Ropars, Jean-Baptiste Charbonnier, Martin Jinek, Andrè Nussenzweig, Taekjip Ha, Peter Cejka
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing. Nature communications 15 (1) (2024)
Giordano Reginato, Maria Rosaria Dello Stritto, Yanbo Wang, Jingzhou Hao, Raphael S Pavani, Michael Schmitz, Swagata Halder, Vincent Morin, Elda Cannavo, Ilaria Ceppi, Stefan Braunshier, Ananya Acharya, Virginie Ropars, Jean-Baptiste Charbonnier, Martin Jinek, Andrè Nussenzweig, Taekjip Ha, Peter Cejka
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing. Nature communications 15 (1) (2024)
Aakash Saha, Mohd Ahsan, Pablo R Arantes, Michael Schmitz, Christelle Chanez, Martin Jinek, Giulia Palermo
An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a. Nature communications 15 (1) (2024)
Javier Aguirre Rivera, Guanzhong Mao, Anton Sabantsev, Mikhail Panfilov, Q Hou, M Lindell, Christelle Chanez, Felix Ritort, Martin Jinek, Sebastian Deindl
Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips. Science (New York, N.Y.) 385 (6711) (2024)
Yanik Weber, Désirée Böck, Anastasia Ivașcu, Nicolas Mathis, Tanja Rothgangl, Eleonora I Ioannidi, Alex C Blaudt, Lisa Tidecks, Máté Vadovics, Hiromi Muramatsu, Andreas Reichmuth, Kim Fabiano Marquart, Lucas Kissling, Norbert Pardi, Martin Jinek, Gerald Schwank
Enhancing prime editor activity by directed protein evolution in yeast. Nature communications 15 (1) (2024)
Giordano Reginato, Maria Rosaria Dello Stritto, Yanbo Wang, Jingzhou Hao, Raphael S Pavani, Michael Schmitz, Swagata Halder, Vincent Morin, Elda Cannavo, Ilaria Ceppi, Stefan Braunshier, Ananya Acharya, Virginie Ropars, Jean-Baptiste Charbonnier, Martin Jinek, Andrè Nussenzweig, Taekjip Ha, Peter Cejka
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing. Nature communications 15 (1) (2024)
Giada Finocchio, Balwina Koopal, Ana Potocnik, Clint Heijstek, Adrie H Westphal, Martin Jinek, Daan C Swarts
Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic acids research 52 (4) (2024)
Carolien Bastiaanssen, Pilar Bobadilla Ugarte, Kijun Kim, Giada Finocchio, Yanlei Feng, Todd A Anzelon, Stephan Köstlbacher, Daniel Tamarit, Thijs J G Ettema, Martin Jinek, Ian J MacRae, Chirlmin Joo, Daan C Swarts, Fabai Wu
RNA-guided RNA silencing by an Asgard archaeal Argonaute. Nature communications 15 (1) (2024)
Aakash Saha, Mohd Ahsan, Pablo R Arantes, Michael Schmitz, Christelle Chanez, Martin Jinek, Giulia Palermo
An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a. Nature communications 15 (1) (2024)
Yanik Weber, Désirée Böck, Anastasia Ivașcu, Nicolas Mathis, Tanja Rothgangl, Eleonora I Ioannidi, Alex C Blaudt, Lisa Tidecks, Máté Vadovics, Hiromi Muramatsu, Andreas Reichmuth, Kim Fabiano Marquart, Lucas Kissling, Norbert Pardi, Martin Jinek, Gerald Schwank
Enhancing prime editor activity by directed protein evolution in yeast. Nature communications 15 (1) (2024)
Carolien Bastiaanssen, Pilar Bobadilla Ugarte, Kijun Kim, Giada Finocchio, Yanlei Feng, Todd A Anzelon, Stephan Köstlbacher, Daniel Tamarit, Thijs J G Ettema, Martin Jinek, Ian J MacRae, Chirlmin Joo, Daan C Swarts, Fabai Wu
RNA-guided RNA silencing by an Asgard archaeal Argonaute. Nature communications 15 (1) (2024)
Yanik Weber, Désirée Böck, Anastasia Ivașcu, Nicolas Mathis, Tanja Rothgangl, Eleonora I Ioannidi, Alex C Blaudt, Lisa Tidecks, Máté Vadovics, Hiromi Muramatsu, Andreas Reichmuth, Kim Fabiano Marquart, Lucas Kissling, Norbert Pardi, Martin Jinek, Gerald Schwank
Enhancing prime editor activity by directed protein evolution in yeast. Nature communications 15 (1) (2024)
Aakash Saha, Mohd Ahsan, Pablo R Arantes, Michael Schmitz, Christelle Chanez, Martin Jinek, Giulia Palermo
An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a. Nature communications 15 (1) (2024)
Giordano Reginato, Maria Rosaria Dello Stritto, Yanbo Wang, Jingzhou Hao, Raphael S Pavani, Michael Schmitz, Swagata Halder, Vincent Morin, Elda Cannavo, Ilaria Ceppi, Stefan Braunshier, Ananya Acharya, Virginie Ropars, Jean-Baptiste Charbonnier, Martin Jinek, Andrè Nussenzweig, Taekjip Ha, Peter Cejka
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing. Nature communications 15 (1) (2024)
Javier Aguirre Rivera, Guanzhong Mao, Anton Sabantsev, Mikhail Panfilov, Q Hou, M Lindell, Christelle Chanez, Felix Ritort, Martin Jinek, Sebastian Deindl
Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips. Science (New York, N.Y.) 385 (6711) (2024)
Luuk Loeff, David William Adams, Christelle Chanez, Sandrine Stutzmann, Laurie Righi, Melanie Blokesch, Martin Jinek
Molecular mechanism of plasmid elimination by the DdmDE defense system. Science (New York, N.Y.) (2024)
Luuk Loeff, David William Adams, Christelle Chanez, Sandrine Stutzmann, Laurie Righi, Melanie Blokesch, Martin Jinek
Molecular mechanism of plasmid elimination by the DdmDE defense system. Science (New York, N.Y.) 385 (6705) (2024)
Luuk Loeff, David William Adams, Christelle Chanez, Sandrine Stutzmann, Laurie Righi, Melanie Blokesch, Martin Jinek
Molecular mechanism of plasmid elimination by the DdmDE defense system. Science (New York, N.Y.) 385 (6705) (2024)
Giada Finocchio, Balwina Koopal, Ana Potocnik, Clint Heijstek, Adrie H Westphal, Martin Jinek, Daan C Swarts
Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic acids research 52 (4) (2024)
Carolien Bastiaanssen, Pilar Bobadilla Ugarte, Kijun Kim, Giada Finocchio, Yanlei Feng, Todd A Anzelon, Stephan Köstlbacher, Daniel Tamarit, Thijs J G Ettema, Martin Jinek, Ian J MacRae, Chirlmin Joo, Daan C Swarts, Fabai Wu
RNA-guided RNA silencing by an Asgard archaeal Argonaute. Nature communications 15 (1) (2024)
Aakash Saha, Mohd Ahsan, Pablo R Arantes, Michael Schmitz, Christelle Chanez, Martin Jinek, Giulia Palermo
An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a. Nature communications 15 (1) (2024)
Carolien Bastiaanssen, Pilar Bobadilla Ugarte, Kijun Kim, Giada Finocchio, Yanlei Feng, Todd A Anzelon, Stephan Köstlbacher, Daniel Tamarit, Thijs J G Ettema, Martin Jinek, Ian J MacRae, Chirlmin Joo, Daan C Swarts, Fabai Wu
RNA-guided RNA silencing by an Asgard archaeal Argonaute. Nature communications 15 (1) (2024)
Yanik Weber, Désirée Böck, Anastasia Ivașcu, Nicolas Mathis, Tanja Rothgangl, Eleonora I Ioannidi, Alex C Blaudt, Lisa Tidecks, Máté Vadovics, Hiromi Muramatsu, Andreas Reichmuth, Kim Fabiano Marquart, Lucas Kissling, Norbert Pardi, Martin Jinek, Gerald Schwank
Enhancing prime editor activity by directed protein evolution in yeast. Nature communications 15 (1) (2024)
Aakash Saha, Mohd Ahsan, Pablo R Arantes, Michael Schmitz, Christelle Chanez, Martin Jinek, Giulia Palermo
An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a. Nature communications 15 (1) (2024)
Giada Finocchio, Balwina Koopal, Ana Potocnik, Clint Heijstek, Adrie H Westphal, Martin Jinek, Daan C Swarts
Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic acids research 52 (4) (2024)
Giada Finocchio, Balwina Koopal, Ana Potocnik, Clint Heijstek, Adrie H Westphal, Martin Jinek, Daan C Swarts
Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic acids research (2024)
Lin Zhao, Sabrina R T Koseki, Rachel A Silverstein, Nadia Amrani, Christina Peng, Christian Kramme, Natasha Savic, Martin Pacesa, Tomas C Rodriguez, Teodora Stan, Emma Tysinger, Lauren Hong, Vivian Yudistyra, Manvitha R Ponnapati, Joseph M Jacobson, George M Church, Noah Jakimo, Ray Truant, Martin Jinek, Benjamin P Kleinstiver, Erik J Sontheimer, Pranam Chatterjee
PAM-flexible genome editing with an engineered chimeric Cas9. Nature communications 14 (1) (2023)
Lukas Schmidheini, Nicolas Mathis, Kim Fabiano Marquart, Tanja Rothgangl, Lucas Kissling, Désirée Böck, Christelle Chanez, Jingrui Priscilla Wang, Martin Jinek, Gerald Schwank
Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility. Nature chemical biology (2023)
Martin Pacesa, Luuk Loeff, Irma Querques, Lena Maria Muckenfuss, Marta Sawicka, Martin Jinek
Publisher Correction: R-loop formation and conformational activation mechanisms of Cas9. Nature (2023)
Kenny Jungfer, Annina Sigg, Martin Jinek
Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic acids research (2023)
Sabrina Koseki, Lauren Hong, Vivian Yudistyra, Teodora Stan, Emma Tysinger, Rachel Silverstein, Christian Kramme, Nadia Amrani, Natasha Savic, Martin Pacesa, Tomas C Rodriguez, Manvitha Ponnapati, Joseph Jacobson, George Church, Ray Truant, Martin Jinek, Benjamin P Kleinstiver, Erik J Sontheimer, Pranam Chatterjee
PAM-Flexible Genome Editing with an Engineered Chimeric Cas9. Research square (2023)
Martin Pacesa, Luuk Loeff, Irma Querques, Lena Maria Muckenfuss, Marta Sawicka, Martin Jinek
R-loop formation and conformational activation mechanisms of Cas9. Nature 609 (7925) (2022)
Lena Maria Muckenfuss, Anabel Carmen Migenda Herranz, Franziska Maria Boneberg, Marcello Clerici, Martin Jinek
Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis. eLife 11 (2022)
Irma Querques, Michael Schmitz, Seraina Oberli, Christelle Chanez, Martin Jinek
Target site selection and remodelling by type V CRISPR-transposon systems. Nature 599 (7885) (2021)
Alena Kroupova, Fabian Ackle, Igor Asanović, Stefan Weitzer, Franziska M Boneberg, Marco Faini, Alexander Leitner, Alessia Chui, Ruedi Aebersold, Javier Martinez, Martin Jinek
Molecular architecture of the human tRNA ligase complex. eLife 10 (2021)
Praveen Bawankar, Tina Lence, Chiara Paolantoni, Irmgard U Haussmann, Migle Kazlauskiene, Dominik Jacob, Jan B Heidelberger, Florian M Richter, Mohanakarthik P Nallasivan, Violeta Morin, Nastasja Kreim, Petra Beli, Mark Helm, Martin Jinek, Matthias Soller, Jean-Yves Roignant
Hakai is required for stabilization of core components of the m6A mRNA methylation machinery. Nature communications 12 (1) (2021)
Tanja Rothgangl, Melissa K Dennis, Paulo J C Lin, Rurika Oka, Dominik Witzigmann, Lukas Villiger, Weihong Qi, Martina Hruzova, Lucas Kissling, Daniela Lenggenhager, Costanza Borrelli, Sabina Egli, Nina Frey, Noëlle Bakker, John A Walker, Anastasia P Kadina, Denis V Victorov, Martin Pacesa, Susanne Kreutzer, Zacharias Kontarakis, Andreas E Moor, Martin Jinek, Drew Weissman, Markus Stoffel, Ruben van Boxtel, Kevin Holden, Norbert Pardi, Beat Thöny, Johannes Häberle, Ying K Tam, Sean C Semple, Gerald Schwank
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels. Nature biotechnology 39 (8) (2021)
Carmela Garcia-Doval, Frank Schwede, Christian Berk, Jakob T Rostøl, Ole Niewoehner, Oliver Tejero, Jonathan Hall, Luciano A Marraffini, Martin Jinek
Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6. Nature communications 11 (1) (2020)
Paola H Pinto, Alena Kroupova, Alexander Schleiffer, Karl Mechtler, Martin Jinek, Stefan Weitzer, Javier Martinez
ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity. Science (New York, N.Y.) 369 (6503) (2020)
Franziska M Boneberg, Tobias Brandmann, Lena Kobel, Jasmin van den Heuvel, Katja Bargsten, Lukas Bammert, Ulrike Kutay, Martin Jinek
Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis. RNA (New York, N.Y.) 25 (6) (2019)
Daan C Swarts, Martin Jinek
Cas9 versus Cas12a/Cpf1: Structure-function comparisons and implications for genome editing. Wiley interdisciplinary reviews. RNA 9 (5) (2018)
Marcello Clerici, Marco Faini, Lena M Muckenfuss, Ruedi Aebersold, Martin Jinek
Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex. Nature structural & molecular biology 25 (2) (2018)
Natasa Savic, Femke C A Ringnalda, Helen Lindsay, Christian Berk, Katja Bargsten, Yizhou Li, Dario Neri, Mark D Robinson, Constance Ciaudo, Jonathan Hall, Martin Jinek, Gerald Schwank
Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair. eLife 7 (2018)
Tobias Brandmann, Hana Fakim, Zoya Padamsi, Ji-Young Youn, Anne-Claude Gingras, Marc R Fabian, Martin Jinek
Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes. The EMBO journal 37 (7) (2018)
Marcello Clerici, Marco Faini, Ruedi Aebersold, Martin Jinek
Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex. eLife 6 (2017)
Paweł Śledź, Martin Jinek
Structural insights into the molecular mechanism of the m(6)A writer complex. eLife 5 (2016)
Alexa Burger, Helen Lindsay, Anastasia Felker, Christopher Hess, Carolin Anders, Elena Chiavacci, Jonas Zaugg, Lukas M Weber, Raul Catena, Martin Jinek, Mark D Robinson, Christian Mosimann
Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes. Development (Cambridge, England) 143 (11) (2016)

Martin Jinek.css-eqlu8i{font-size:small;padding-left:4px;} (M Jinek)

Publication Activity (10 Years)

Top Topics

Top Venues

Martin Jinek (M Jinek)