Jonathan S Weissman (Jonathan Weissman)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 68

Top Topics

Gene Expression

Machine Learning

Top Venues

Nature biotechnology

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature (2024)
Lukas Villiger, Julia Joung, Luke Koblan, Jonathan S Weissman, Omar O Abudayyeh, Jonathan Samuel Gootenberg
CRISPR technologies for genome, epigenome and transcriptome editing. Nature reviews. Molecular cell biology (2024)
Lukas Villiger, Julia Joung, Luke Koblan, Jonathan S Weissman, Omar O Abudayyeh, Jonathan Samuel Gootenberg
CRISPR technologies for genome, epigenome and transcriptome editing. Nature reviews. Molecular cell biology (2024)
Chen Weng, Jonathan S Weissman, Vijay G Sankaran
Robustness and reliability of single-cell regulatory multi-omics with deep mitochondrial mutation profiling. bioRxiv : the preprint server for biology (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human hematopoiesis. Nature (2024)
Ezgi Hacisuleyman, Caryn R Hale, Natalie Noble, Ji-Dung Luo, John J Fak, Misa Saito, Jin Chen, Jonathan S Weissman, Robert B Darnell
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nature neuroscience 27 (5) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Lukas Villiger, Julia Joung, Luke Koblan, Jonathan S Weissman, Omar O Abudayyeh, Jonathan Samuel Gootenberg
CRISPR technologies for genome, epigenome and transcriptome editing. Nature reviews. Molecular cell biology 25 (6) (2024)
Ezgi Hacisuleyman, Caryn R Hale, Natalie Noble, Ji-Dung Luo, John J Fak, Misa Saito, Jin Chen, Jonathan S Weissman, Robert B Darnell
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nature neuroscience 27 (5) (2024)
Ezgi Hacisuleyman, Caryn R Hale, Natalie Noble, Ji-Dung Luo, John J Fak, Misa Saito, Jin Chen, Jonathan S Weissman, Robert B Darnell
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nature neuroscience 27 (5) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human hematopoiesis. Nature (2024)
Edwin N Neumann, Tessa M Bertozzi, Elaine Wu, Fiona Serack, John W Harvey, Pamela P Brauer, Catherine P Pirtle, Alissa Coffey, Michael Howard, Nikita Kamath, Kenney Lenz, Kenia Guzman, Michael H Raymond, Ahmad S Khalil, Benjamin E Deverman, Eric Vallabh Minikel, Sonia M Vallabh, Jonathan S Weissman
Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor. Science (New York, N.Y.) 384 (6703) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human hematopoiesis. Nature (2024)
Ezgi Hacisuleyman, Caryn R Hale, Natalie Noble, Ji-Dung Luo, John J Fak, Misa Saito, Jin Chen, Jonathan S Weissman, Robert B Darnell
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nature neuroscience 27 (5) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Lukas Villiger, Julia Joung, Luke Koblan, Jonathan S Weissman, Omar O Abudayyeh, Jonathan Samuel Gootenberg
CRISPR technologies for genome, epigenome and transcriptome editing. Nature reviews. Molecular cell biology 25 (6) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Lukas Villiger, Julia Joung, Luke Koblan, Jonathan S Weissman, Omar O Abudayyeh, Jonathan Samuel Gootenberg
CRISPR technologies for genome, epigenome and transcriptome editing. Nature reviews. Molecular cell biology (2024)
Ezgi Hacisuleyman, Caryn R Hale, Natalie Noble, Ji-Dung Luo, John J Fak, Misa Saito, Jin Chen, Jonathan S Weissman, Robert B Darnell
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nature neuroscience (2024)
Ezgi Hacisuleyman, Caryn R Hale, Natalie Noble, Ji-Dung Luo, John J Fak, Misa Saito, Jin Chen, Jonathan S Weissman, Robert B Darnell
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nature neuroscience 27 (5) (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Edwin N Neumann, Tessa M Bertozzi, Elaine Wu, Fiona Serack, John W Harvey, Pamela P Brauer, Catherine P Pirtle, Alissa Coffey, Michael Howard, Nikita Kamath, Kenney Lenz, Kenia Guzman, Michael H Raymond, Ahmad S Khalil, Benjamin E Deverman, Eric Vallabh Minikel, Sonia M Vallabh, Jonathan S Weissman
Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor. Science (New York, N.Y.) 384 (6703) (2024)
Ezgi Hacisuleyman, Caryn R Hale, Natalie Noble, Ji-Dung Luo, John J Fak, Misa Saito, Jin Chen, Jonathan S Weissman, Robert B Darnell
Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nature neuroscience 27 (5) (2024)
Lukas Villiger, Julia Joung, Luke Koblan, Jonathan S Weissman, Omar O Abudayyeh, Jonathan Samuel Gootenberg
Author Correction: CRISPR technologies for genome, epigenome and transcriptome editing. Nature reviews. Molecular cell biology (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature (2024)
Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L Alexander Liggett, Matthew G Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A Hussmann, Alexandra Schnell, Kathryn E Yost, Luke W Koblan, Jorge D Martin-Rufino, Kyung Hoi Joseph Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari Mallidi, Antonia Kreso, Javier Escabi, William M Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S Weissman, Vijay G Sankaran
Deciphering cell states and genealogies of human haematopoiesis. Nature 627 (8003) (2024)
Asmin Tulpule, Shruti Menon, Marcus Breese, Yone Lin, Hannah Allegakoen, Shruthi Perati, Ann Heslin, Max A Horlbeck, Jonathan S Weissman, E Alejandro Sweet-Cordero, Trever G Bivona
FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer. Research square (2023)
Iain C Clark, Kristina M Fontanez, Robert H Meltzer, Yi Xue, Corey Hayford, Aaron A May-Zhang, Chris D'Amato, Ahmad Osman, Jesse Q Zhang, Pabodha Hettige, Jacob S A Ishibashi, Cyrille L Delley, Daniel W Weisgerber, Joseph M Replogle, Marco Jost, Kiet T Phong, Vanessa E Kennedy, Cheryl A C Peretz, Esther A Kim, Siyou Song, William Karlon, Jonathan S Weissman, Catherine C Smith, Zev J Gartner, Adam R Abate
Microfluidics-free single-cell genomics with templated emulsification. Nature biotechnology (2023)
Richard She, Tyler Fair, Nathan K Schaefer, Reuben A Saunders, Bryan J Pavlovic, Jonathan S Weissman, Alex Aaron Pollen
Comparative landscape of genetic dependencies in human and chimpanzee stem cells. bioRxiv : the preprint server for biology (2023)
Sara Sunshine, Andreas S Puschnik, Joseph M Replogle, Matthew T Laurie, Jamin Liu, Beth Shoshanna Zha, James K Nuñez, Janie R Byrum, Aidan H McMorrow, Matthew B Friemann, Juliane Winkler, Xiaojie Qiu, Oren S Rosenberg, Manuel D Leonetti, Chun Jimmie Ye, Jonathan S Weissman, Joseph L DeRisi, Marco Y Hein
Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq. Nature communications 14 (1) (2023)
Luke W Koblan, Mandana Arbab, Max W Shen, Jeffrey A Hussmann, Andrew V Anzalone, Jordan L Doman, Gregory A Newby, Dian Yang, Beverly Mok, Joseph M Replogle, Albert Xu, Tyler A Sisley, Jonathan S Weissman, Britt Adamson, David R Liu
Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning. Nature biotechnology (2023)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Fulong Yu, Liam D Cato, Chen Weng, L Alexander Liggett, Soyoung Jeon, Keren Xu, Charleston W K Chiang, Joseph L Wiemels, Jonathan S Weissman, Adam J de Smith, Vijay G Sankaran
Variant to function mapping at single-cell resolution through network propagation. Nature biotechnology 40 (11) (2022)
Vijay G Sankaran, Jonathan S Weissman, Leonard I Zon
Cellular barcoding to decipher clonal dynamics in disease. Science (New York, N.Y.) 378 (6616) (2022)
Alina Guna, Taylor Anthony Stevens, Alison J Inglis, Joseph M Replogle, Theodore K Esantsi, Gayathri Muthukumar, Kelly C L Shaffer, Maxine L Wang, Angela N Pogson, Jeffrey J Jones, Brett Lomenick, Tsui-Fen Chou, Jonathan S Weissman, Rebecca M Voorhees
MTCH2 is a mitochondrial outer membrane protein insertase. Science (New York, N.Y.) 378 (6617) (2022)
Avi J Samelson, Quang Dinh Tran, Rémy Robinot, Lucia Carrau, Veronica V Rezelj, Alice Mac Kain, Merissa Chen, Gokul N Ramadoss, Xiaoyan Guo, Shion An Lim, Irene Lui, James K Nuñez, Sarah J Rockwood, Jianhui Wang, Na Liu, Jared Carlson-Stevermer, Jennifer Oki, Travis Maures, Kevin Holden, Jonathan S Weissman, James A Wells, Bruce R Conklin, Benjamin R tenOever, Lisa A Chakrabarti, Marco Vignuzzi, Ruilin Tian, Martin Edward Kampmann
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2. Nature cell biology 24 (1) (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Jonathan M Mudge, Jorge Ruiz-Orera, John R Prensner, Marie A Brunet, Ferriol Calvet, Irwin Jungreis, Jose Manuel Gonzalez, Michele Magrane, Cholsoon Jang, Jana Felicitas Schulz, Yucheng T Yang, M Mar Albà, Julie L Aspden, Pavel V Baranov, Ariel Alejandro Bazzini, Elspeth A Bruford, Maria Jesus Martin, Lorenzo Calviello, Anne-Ruxandra Carvunis, Jin Chen, Juan Pablo Couso, Eric W Deutsch, Paul Flicek, Adam Frankish, Mark Gerstein, Norbert Hübner, Nicholas T Ingolia, Manolis Kellis, Gerben Menschaert, Robert L Moritz, Uwe Ohler, Xavier Roucou, Alan Saghatelian, Jonathan S Weissman, Sebastiaan van Heesch
Standardized annotation of translated open reading frames. Nature biotechnology 40 (7) (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Bhairavi Tolani, Anna Celli, Yanmin Yao, Yong Zi Tan, Richard Fetter, Christina R Liem, Adam J de Smith, Thamiya Vasanthakumar, Paola Bisignano, Adam D Cotton, Ian B Seiple, John L Rubinstein, Marco Jost, Jonathan S Weissman
Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice. Nature biotechnology (2022)
Nathan H Cho, Keith C Cheveralls, Andreas-David Brunner, Kibeom Kim, André C Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y Li, Hera Canaj, James Y S Kim, Edna M Stewart, Christian Gnann, Frank McCarthy, Joana P Cabrera, Rachel M Brunetti, Bryant B Chhun, Greg Dingle, Marco Y Hein, Bo Huang, Shalin B Mehta, Jonathan S Weissman, Rafael Gómez-Sjöberg, Daniel N Itzhak, Loïc Alain Royer, Matthias Mann, Manuel D Leonetti
OpenCell: Endogenous tagging for the cartography of human cellular organization. Science (New York, N.Y.) 375 (6585) (2022)
Noa Dahan, Yury S Bykov, Elizabeth A Boydston, Amir Fadel, Zohar Gazi, Hodaya Hochberg-Laufer, James Martenson, Vladimir Denic, Yaron Shav-Tal, Jonathan S Weissman, Naama Aviram, Einat Zalckvar, Maya Schuldiner
Peroxisome function relies on organelle-associated mRNA translation. Science advances 8 (2) (2022)
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier, Yufang Ding, Baylee J Russell, Xingren Wang, Kun Leng, Alina Guna, Thomas M Norman, Ryan A Pak, Daniel M Ramos, Michael Emmerson Ward, Luke A Gilbert, Martin Edward Kampmann, Jonathan S Weissman, Marco Jost
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors. eLife 11 (2022)
Jeffrey J Quinn, Matthew G Jones, Ross A Okimoto, Shigeki Nanjo, Michelle M Chan, Nir Yosef, Trever G Bivona, Jonathan S Weissman
Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts. Science (New York, N.Y.) 371 (6532) (2021)
Marco Y Hein, Jonathan S Weissman
Functional single-cell genomics of human cytomegalovirus infection. Nature biotechnology (2021)
Marco Jost, Amy N Jacobson, Jeffrey A Hussmann, Giana Cirolia, Michael A Fischbach, Jonathan S Weissman
CRISPR-based functional genomics in human dendritic cells. eLife 10 (2021)
Luke W Koblan, Mandana Arbab, Max W Shen, Jeffrey A Hussmann, Andrew V Anzalone, Jordan L Doman, Gregory A Newby, Dian Yang, Beverly Mok, Joseph M Replogle, Albert Xu, Tyler A Sisley, Jonathan S Weissman, Britt Adamson, David R Liu
Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning. Nature biotechnology 39 (11) (2021)
Joseph M Replogle, Thomas M Norman, Albert Xu, Jeffrey A Hussmann, Jin Chen, J Zachery Cogan, Elliott J Meer, Jessica M Terry, Daniel P Riordan, Niranjan Srinivas, Ian T Fiddes, Joseph G Arthur, Luigi J Alvarado, Katherine A Pfeiffer, Tarjei S Mikkelsen, Jonathan S Weissman, Britt Adamson
Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing. Nature biotechnology 38 (8) (2020)
Max A Horlbeck, S John Liu, Howard Y Chang, Daniel A Lim, Jonathan S Weissman
Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes. Nature biotechnology 38 (5) (2020)
Lakshmi E Miller-Vedam, Bastian Bräuning, Katerina D Popova, Nicole T Schirle Oakdale, Jessica L Bonnar, Jesuraj R Prabu, Elizabeth A Boydston, Natalia Sevillano, Matthew J Shurtleff, Robert M Stroud, Charles S Craik, Brenda A Schulman, Adam Frost, Jonathan S Weissman
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. eLife 9 (2020)
Ke Zou, Silvia Rouskin, Kevin Dervishi, Mark A McCormick, Arjun Sasikumar, Changhui Deng, Matt Kaeberlein, Rachel B Brem, Michael Polymenis, Brian Keith Kennedy, Jonathan S Weissman, Jiashun Zheng, Qi Ouyang, Hao Li
Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span. Science advances 6 (32) (2020)
Marco Jost, Daniel A Santos, Reuben A Saunders, Max A Horlbeck, John S Hawkins, Sonia M Scaria, Thomas M Norman, Jeffrey A Hussmann, Christina R Liem, Carol A Gross, Jonathan S Weissman
Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs. Nature biotechnology 38 (3) (2020)
Jin Chen, Andreas-David Brunner, J Zachery Cogan, James K Nuñez, Alexander P Fields, Britt Adamson, Daniel N Itzhak, Jason Y Li, Matthias Mann, Manuel D Leonetti, Jonathan S Weissman
Pervasive functional translation of noncanonical human open reading frames. Science (New York, N.Y.) 367 (6482) (2020)
Ashley M Ngo, Matthew J Shurtleff, Katerina D Popova, Jessie Kulsuptrakul, Jonathan S Weissman, Andreas S Puschnik
The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins. eLife 8 (2019)
Sandra Elizabeth Torres, Ciara M Gallagher, Lars Plate, Meghna Gupta, Christina R Liem, Xiaoyan Guo, Ruilin Tian, Robert M Stroud, Martin Edward Kampmann, Jonathan S Weissman, Peter Walter
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. eLife 8 (2019)
Thomas M Norman, Max A Horlbeck, Joseph M Replogle, Alex Y Ge, Albert Xu, Marco Jost, Luke A Gilbert, Jonathan S Weissman
Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science (New York, N.Y.) 365 (6455) (2019)
Elizabeth A Boydston, Kelly Subramanian, Jodi Nunnari, Jonathan S Weissman
Defining the physiological role of SRP in protein-targeting efficiency and specificity. Science (New York, N.Y.) 359 (6376) (2018)
Kamena K Kostova, Kelsey L Hickey, Beatriz A Osuna, Jeffrey A Hussmann, Adam Frost, David E Weinberg, Jonathan S Weissman
CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Science (New York, N.Y.) 357 (6349) (2018)
Weihan Li, Voytek Okreglak, Jirka Peschek, Philipp Kimmig, Meghan Zubradt, Jonathan S Weissman, Peter Walter
Engineering ER-stress dependent non-conventional mRNA splicing. eLife 7 (2018)
Alexander J Martinko, Charles Truillet, Olivier Julien, Juan E Diaz, Max A Horlbeck, Gordon Whiteley, Josip Blonder, Jonathan S Weissman, Sourav Bandyopadhyay, Michael J Evans, James A Wells
Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins. eLife 7 (2018)
Matthew J Shurtleff, Daniel N Itzhak, Jeffrey A Hussmann, Nicole T Schirle Oakdale, Elizabeth A Boydston, Martin Jonikas, Jimena Weibezahn, Katerina D Popova, Calvin H Jan, Pavel Sinitcyn, Shruthi S Vembar, Hilda Hernandez, Jürgen Cox, Alma L Burlingame, Jeffrey L Brodsky, Adam Frost, Georg H H Borner, Jonathan S Weissman
The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. eLife 7 (2018)
Zhou Yu, Lauren E Surface, Chong Yon Park, Max A Horlbeck, Gregory A Wyant, Monther Abu-Remaileh, Timothy R Peterson, David M Sabatini, Jonathan S Weissman, Erin K O'Shea
Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates. eLife 7 (2018)
Aviv Regev, Sarah A Teichmann, Eric S Lander, Ido Amit, Christophe Benoist, Ewan Birney, Bernd Bodenmiller, Peter Campbell, Piero Carnici, Menna Clatworthy, Hans Clevers, Bart Deplancke, Ian Dunham, James Eberwine, Roland Eils, Wolfgang Enard, Andrew Farmer, Lars Fugger, Berthold Göttgens, Nir Hacohen, Muzlifah A Haniffa, Martin Hemberg, Seung Kim, Paul Klenerman, Arnold Kriegstein, Ed S Lein, Sten Linnarsson, Emma Lundberg, Joakim Lundeberg, Partha Majumder, John C Marioni, Miriam Merad, Musa Mhlanga, Martijn Nawijn, Mihai Netea, Garry Nolan, Dana Pe'er, Anthony Phillipakis, Chris Paul Ponting, Stephen Quake, Wolf Reik, Orit Rozenblatt-Rosen, Joshua R Sanes, Rahul Satija, Ton N Schumacher, Alex Shalek, Ehud Shapiro, Padmanee Sharma, Jay W Shin, Oliver Stegle, Michael Stratton, Michael J T Stubbington, Fabian J Theis, Matthias Uhlen, Alexander van Oudenaarden, Allon Wagner, Fiona M Watt, Jonathan S Weissman, Barbara Wold, Ramnik Xavier, Nir Yosef, null null
The Human Cell Atlas. eLife 6 (2017)
David H Burkhardt, Silvi Rouskin, Yan Zhang, Gene-Wei Li, Jonathan S Weissman, Carol A Gross
Operon mRNAs are organized into ORF-centric structures that predict translation efficiency. eLife 6 (2017)
Max A Horlbeck, Luke A Gilbert, Jacqueline E Villalta, Britt Adamson, Ryan A Pak, Yuwen Chen, Alexander P Fields, Chong Yon Park, Jacob E Corn, Martin Edward Kampmann, Jonathan S Weissman
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. eLife 5 (2016)