Deborah T Hung (Deb Hung, Deborah Hung)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 47

Top Topics

Pseudomonas Aeruginosa

Immune Response

Top Venues

ACS infectious diseases

ACS chemical biology

Journal of bacteriology

This page only lists publications with an associated author ORCID identifier.

Publications

Michael G Wuo, Charles L Dulberger, Theodore C Warner, Robert A Brown, Alexander Sturm, Eveline Ultee, Zohar Bloom-Ackermann, Catherine Choi, Junhao Zhu, Ethan C Garner, Ariane Briegel, Deborah T Hung, Eric J Rubin, Laura L Kiessling
Fluorogenic Probes of the Mycobacterial Membrane as Reporters of Antibiotic Action. Journal of the American Chemical Society 146 (26) (2024)
Keith P Romano, Josephine Bagnall, Thulasi Warrier, Jaryd R Sullivan, Kristina Ferrara, Marek Orzechowski, Phuong H Nguyen, Kyra Raines, Jonathan Livny, Noam Shoresh, Deborah T Hung
Perturbation-Specific Transcriptional Mapping for unbiased target elucidation of antibiotics. bioRxiv : the preprint server for biology (2024)
Ian R Humphreys, Jing Zhang, Minkyung Baek, Yaxi Wang, Aditya Krishnakumar, Jimin Pei, Ivan Anishchenko, Catherine A Tower, Blake A Jackson, Thulasi Warrier, Deborah T Hung, S Brook Peterson, Joseph D Mougous, Qian Cong, Julien S Baker
Protein interactions in human pathogens revealed through deep learning. Nature microbiology (2024)
Donavan Marcus Neo, Anne E Clatworthy, Deborah T Hung
A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in Mycobacterium abscessus . Journal of bacteriology 206 (3) (2024)
Donavan Marcus Neo, Anne E Clatworthy, Deborah T Hung
A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in Mycobacterium abscessus . Journal of bacteriology 206 (3) (2024)
Margarita Parada-Kusz, Anne E Clatworthy, Emily R Goering, Stephanie M Blackwood, Jack Y Shigeta, Eivgeni Mashin, Elizabeth J Salm, Catherine Choi, Senya Combs, Jenny S W Lee, Carlos A Rodriguez-Osorio, Andrew T Chan, Susumu Tomita, Deborah T Hung
3-Hydroxykynurenine targets kainate receptors to promote defense against infection. Nature chemical biology (2024)
Donavan Marcus Neo, Anne E Clatworthy, Deborah T Hung
A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in Mycobacterium abscessus . Journal of bacteriology 206 (3) (2024)
Alexander Sturm, Penny Sun, Julian Avila-Pacheco, Anne E Clatworthy, Zohar Bloom-Ackermann, Michael G Wuo, James E Gomez, Soomin Jin, Clary B Clish, Laura L Kiessling, Deborah T Hung
Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis . mBio 15 (2) (2024)
Donavan Marcus Neo, Anne E Clatworthy, Deborah T Hung
A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in Mycobacterium abscessus . Journal of bacteriology 206 (3) (2024)
Keith P Romano, Josephine Bagnall, Thulasi Warrier, Jaryd R Sullivan, Kristina Ferrara, Marek Orzechowski, Phuong H Nguyen, Kyra Raines, Jonathan Livny, Noam Shoresh, Deborah T Hung
Perturbation-Specific Transcriptional Mapping facilitates unbiased target elucidation of antibiotics. bioRxiv : the preprint server for biology (2024)
Michael G Wuo, Charles L Dulberger, Theodore C Warner, Robert A Brown, Alexander Sturm, Eveline Ultee, Zohar Bloom-Ackermann, Catherine Choi, Junhao Zhu, Ethan C Garner, Ariane Briegel, Deborah T Hung, Eric J Rubin, Laura L Kiessling
Fluorogenic Probes of the Mycobacterial Membrane as Reporters of Antibiotic Action. Journal of the American Chemical Society (2024)
Margarita Parada-Kusz, Anne E Clatworthy, Emily R Goering, Stephanie M Blackwood, Jack Y Shigeta, Eivgeni Mashin, Elizabeth J Salm, Catherine Choi, Senya Combs, Jenny S W Lee, Carlos A Rodriguez-Osorio, Andrew T Chan, Susumu Tomita, Deborah T Hung
3-Hydroxykynurenine targets kainate receptors to promote defense against infection. Nature chemical biology (2024)
Keith P Romano, Josephine Bagnall, Thulasi Warrier, Jaryd R Sullivan, Kristina Ferrara, Marek Orzechowski, Phuong H Nguyen, Kyra Raines, Jonathan Livny, Noam Shoresh, Deborah T Hung
Perturbation-Specific Transcriptional Mapping for unbiased target elucidation of antibiotics. bioRxiv : the preprint server for biology (2024)
Donavan Marcus Neo, Anne E Clatworthy, Deborah T Hung
A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in Mycobacterium abscessus . Journal of bacteriology (2024)
Keith P Romano, Josephine Bagnall, Thulasi Warrier, Jaryd R Sullivan, Kristina Ferrara, Marek Orzechowski, Phuong H Nguyen, Kyra Raines, Jonathan Livny, Noam Shoresh, Deborah T Hung
Perturbation-Specific Transcriptional Mapping for unbiased target elucidation of antibiotics. bioRxiv : the preprint server for biology (2024)
Alexander Sturm, Penny Sun, Julian Avila-Pacheco, Anne E Clatworthy, Zohar Bloom-Ackermann, Michael G Wuo, James E Gomez, Soomin Jin, Clary B Clish, Laura L Kiessling, Deborah T Hung
Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis . mBio 15 (2) (2024)
Alexander Sturm, Penny Sun, Julian Avila-Pacheco, Anne E Clatworthy, Zohar Bloom-Ackermann, Michael G Wuo, James E Gomez, Soomin Jin, Clary B Clish, Laura L Kiessling, Deborah T Hung
Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis . mBio 15 (2) (2024)
Alexander Sturm, Penny Sun, Julian Avila-Pacheco, Anne E Clatworthy, Zohar Bloom-Ackermann, Michael G Wuo, James E Gomez, Soomin Jin, Clary B Clish, Laura L Kiessling, Deborah T Hung
Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis . mBio (2024)
Margarita Parada-Kusz, Anne E Clatworthy, Emily R Goering, Stephanie M Blackwood, Jack Y Shigeta, Eivgeni Mashin, Elizabeth J Salm, Catherine Choi, Senya Combs, Jenny S W Lee, Carlos A Rodriguez-Osorio, Andrew T Chan, Susumu Tomita, Deborah T Hung
3-Hydroxykynurenine targets kainate receptors to promote defense against infection. Nature chemical biology (2024)
Alexander Sturm, Penny Sun, Julian Avila-Pacheco, Anne E Clatworthy, Zohar Bloom-Ackermann, Michael G Wuo, James E Gomez, Soomin Jin, Clary B Clish, Laura L Kiessling, Deborah T Hung
Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis . mBio 15 (2) (2024)
Azin Saebi, Joseph S Brown, Victoria M Marando, Nina Hartrampf, Nicole M Chumbler, Stephanie Hanna, Mackenzie Poskus, Andrei Loas, Laura L Kiessling, Deborah T Hung, Bradley L Pentelute
Rapid Single-Shot Synthesis of the 214 Amino Acid-Long N-Terminal Domain of Pyocin S2. ACS chemical biology (2023)
Michael G Wuo, Amanda E Dugan, Melanie Halim, Blake M Hauser, Jared Feldman, Timothy M Caradonna, Shuting Zhang, Lauren E Pepi, Caroline Atyeo, Stephanie Fischinger, Galit Alter, Wilfredo F Garcia-Beltran, Parastoo Azadi, Deborah T Hung, Aaron G Schmidt, Laura L Kiessling
Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV-2. ACS central science 9 (5) (2023)
Shuting Zhang, Peijun Ma, Marek Orzechowski, Allison Lemmer, Kara Rzasa, Josephine Bagnall, Sulyman Barkho, Michael Chen, Lorri He, Raymond Neitupski, Victoria Tran, Ross Ackerman, Emily Gath, Austin Bond, Giana Frongillo, Thomas Cleland, Aaron Golas, Anthony Gaca, Michael Fitzgerald, Kathleen Kelly, Kelsey Hazegh, Larry Dumont, Corey Hoffman, Mary J Homer, Peter Marks, Ann Woolley, Sharon Wong, James Gomez, Jonathan Livny, Deborah T Hung
High-Throughput Neutralization and Serology Assays Reveal Correlated but Highly Variable Humoral Immune Responses in a Large Population of Individuals Infected with SARS-CoV-2 in the US between March and August 2020. mBio (2023)
Sara Ahmed, Sultan Chowdhury, James Gomez, Deborah T Hung, Tanya Parish
Benzene Amide Ether Scaffold is Active against Non-replicating and Intracellular Mycobacterium tuberculosis . ACS infectious diseases (2023)
Azin Saebi, Joseph S Brown, Victoria M Marando, Nina Hartrampf, Nicole M Chumbler, Stephanie Hanna, Mackenzie Poskus, Andrei Loas, Laura L Kiessling, Deborah T Hung, Bradley L Pentelute
Rapid Single-Shot Synthesis of the 214 Amino Acid-Long N-Terminal Domain of Pyocin S2. ACS chemical biology 18 (3) (2023)
Azin Saebi, Joseph S Brown, Victoria M Marando, Nina Hartrampf, Nicole M Chumbler, Stephanie Hanna, Mackenzie Poskus, Andrei Loas, Laura L Kiessling, Deborah T Hung, Bradley L Pentelute
Rapid Single-Shot Synthesis of the 214 Amino Acid-Long N-Terminal Domain of Pyocin S2. ACS chemical biology 18 (3) (2023)
Erica N Parker, Brett N Cain, Behnoush Hajian, Rebecca Joy Ulrich, Emily J Geddes, Sulyman Barkho, Hyang Yeon Lee, John D Williams, Malik Raynor, Diana Caridha, Angela Zaino, Mrinal Shekhar, Kristen A Muñoz, Kara M Rzasa, Emily R Temple, Diana Hunt, Xiannu Jin, Chau Vuong, Kristina Pannone, Aya M Kelly, Michael P Mulligan, Katie K Lee, Gee W Lau, Deborah T Hung, Paul J Hergenrother
An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections. ACS central science 8 (8) (2022)
Craig R MacNair, Maya A Farha, Michael H Serrano-Wu, Katie K Lee, Brian Hubbard, Jean-Philippe Côté, Lindsey A Carfrae, Megan M Tu, Jeffrey L Gaulin, Diana K Hunt, Deborah T Hung, Eric D Brown
Preclinical Development of Pentamidine Analogs Identifies a Potent and Nontoxic Antibiotic Adjuvant. ACS infectious diseases 8 (4) (2022)
Cristina Penaranda, Nicole M Chumbler, Deborah T Hung
Dual transcriptional analysis reveals adaptation of host and pathogen to intracellular survival of Pseudomonas aeruginosa associated with urinary tract infection. PLoS pathogens 17 (4) (2021)
Leslie W Chan, Kelsey E Hern, Chayanon Ngambenjawong, Katie Lee, Ester J Kwon, Deborah T Hung, Sangeeta N Bhatia
Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization. ACS infectious diseases 7 (4) (2021)
Yuchen Zhang, Rui Guo, Sharon H Kim, Hardik Shah, Shuting Zhang, Jin Hua Liang, Ying Fang, Matteo Gentili, Colin N O' Leary, Steven J Elledge, Deborah T Hung, Vamsi K Mootha, Benjamin E Gewurz
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication. Nature communications 12 (1) (2021)
Kristina Klobucar, Jean-Philippe Côté, Shawn French, Louis Borrillo, Amelia Bing Ya Guo, Michael H Serrano-Wu, Katie K Lee, Brian Hubbard, Jarrod W Johnson, Jeffrey L Gaulin, Jakob Magolan, Deborah T Hung, Eric D Brown
Chemical Screen for Vancomycin Antagonism Uncovers Probes of the Gram-Negative Outer Membrane. ACS chemical biology 16 (5) (2021)
Peijun Ma, Lorrie L He, Alejandro Pironti, Hannah H Laibinis, Christoph M Ernst, Abigail L Manson, Roby P Bhattacharyya, Ashlee M Earl, Jonathan Livny, Deborah T Hung
Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics. eLife 10 (2021)
Miguel Reyes, Michael R Filbin, Roby P Bhattacharyya, Abraham Sonny, Arnav Mehta, Kianna Billman, Kyle R Kays, Mayra Pinilla-Vera, Maura E Benson, Lisa A Cosimi, Deborah T Hung, Bruce David Levy, Alexandra-Chloé Villani, Moshe Sade-Feldman, Rebecca M Baron, Marcia B Goldberg, Paul C Blainey, Nir Hacohen
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro. Science translational medicine 13 (598) (2021)
Christoph M Ernst, Julian R Braxton, Carlos A Rodriguez-Osorio, Anna P Zagieboylo, Li Li, Alejandro Pironti, Abigail L Manson, Anil V Nair, Maura Benson, Kaelyn Cummins, Anne E Clatworthy, Ashlee M Earl, Lisa A Cosimi, Deborah T Hung
Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae. Nature medicine 26 (5) (2020)
Cristina Penaranda, Deborah T Hung
Single-Cell RNA Sequencing to Understand Host-Pathogen Interactions. ACS infectious diseases 5 (3) (2019)
Viktoria Betin, Cristina Penaranda, Nirmalya Bandyopadhyay, Rui Yang, Angela Abitua, Roby P Bhattacharyya, Amy Fan, Roi Avraham, Jonathan Livny, Noam Shoresh, Deborah T Hung
Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis. Scientific reports 9 (1) (2019)
Roby P Bhattacharyya, Nirmalya Bandyopadhyay, Peijun Ma, Sophie S Son, Jamin Liu, Lorrie L He, Lidan Wu, Rustem Khafizov, Rich Boykin, Gustavo C Cerqueira, Alejandro Pironti, Robert F Rudy, Milesh M Patel, Rui Yang, Jennifer Skerry, Elizabeth Nazarian, Kimberly A Musser, Jill Taylor, Virginia M Pierce, Ashlee M Earl, Lisa A Cosimi, Noam Shoresh, Joseph Beechem, Jonathan Livny, Deborah T Hung
Simultaneous detection of genotype and phenotype enables rapid and accurate antibiotic susceptibility determination. Nature medicine 25 (12) (2019)
Eachan O Johnson, Emma Office, Tomohiko Kawate, Marek Orzechowski, Deborah T Hung
Large-Scale Chemical-Genetic Strategy Enables the Design of Antimicrobial Combination Chemotherapy in Mycobacteria. ACS infectious diseases 6 (1) (2019)
Eachan O Johnson, Deborah T Hung
A Point of Inflection and Reflection on Systems Chemical Biology. ACS chemical biology 14 (12) (2019)
Keith P Romano, Thulasi Warrier, Bradley E Poulsen, Phuong H Nguyen, Alexander R Loftis, Azin Saebi, Bradley L Pentelute, Deborah T Hung
Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy 63 (9) (2019)
Samantha Wellington Miranda, Deborah T Hung
The Expanding Diversity of Mycobacterium tuberculosis Drug Targets. ACS infectious diseases 4 (5) (2018)
Roby P Bhattacharyya, Sri Gowtham Thakku, Deborah T Hung
Harnessing CRISPR Effectors for Infectious Disease Diagnostics. ACS infectious diseases 4 (9) (2018)
Peijun Ma, Hannah H Laibinis, Christoph M Ernst, Deborah T Hung
Carbapenem Resistance Caused by High-Level Expression of OXA-663 β-Lactamase in an OmpK36-Deficient Klebsiella pneumoniae Clinical Isolate. Antimicrobial agents and chemotherapy 62 (11) (2018)
Amy K Barczak, Roi Avraham, Shantanu Singh, Samantha S Luo, Wei Ran Zhang, Mark-Anthony Bray, Amelia E Hinman, Matthew Thompson, Raymond M Nietupski, Aaron Golas, Paul Montgomery, Michael Fitzgerald, Roger S Smith, Dylan W White, Anna D Tischler, Anne E Carpenter, Deborah T Hung
Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence. PLoS pathogens 13 (5) (2017)
James E Gomez, Benjamin B Kaufmann-Malaga, Carl N Wivagg, Peter B Kim, Melanie R Silvis, Nikolai Renedo, Thomas R Ioerger, Rushdy Ahmad, Jonathan Livny, Skye Fishbein, James C Sacchettini, Steven A Carr, Deborah T Hung
Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment. eLife 6 (2017)
Jonathan Samuel Gootenberg, Omar O Abudayyeh, Jeong Wook Lee, Patrick Essletzbichler, Aaron J Dy, Julia Joung, Vanessa Verdine, Nina Donghia, Nichole M Daringer, Catherine A Freije, Cameron A Myhrvold, Roby P Bhattacharyya, Jonathan Livny, Aviv Regev, Eugene V Koonin, Deborah T Hung, Pardis C Sabeti, James J Collins, Feng Zhang
Nucleic acid detection with CRISPR-Cas13a/C2c2. Science (New York, N.Y.) 356 (6336) (2017)