Francesco Fiorentino

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 46

Top Venues

Journal of medicinal chemistry

ChemMedChem

Journal of enzyme inhibition and medicinal chemistry

Pharmaceuticals (Basel, Switzerland)

University of Oxford

Sapienza University of Rome (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Oxford

United Kingdom

PhD student :: Chemistry

Education History

Sapienza University of Rome

Italy

MSC :: Department of Drug Chemistry and Technology

Publications

Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry 67 (3) (2024)
Leonhard H Urner, Francesco Fiorentino, Denis Shutin, Joshua B Sauer, Mark T Agasid, Tarick J El-Baba, Jani Reddy Bolla, Phillip J Stansfeld, Carol V Robinson
Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins. Journal of the American Chemical Society (2024)
Leonhard H Urner, Francesco Fiorentino, Denis Shutin, Joshua B Sauer, Mark T Agasid, Tarick J El-Baba, Jani Reddy Bolla, Phillip J Stansfeld, Carol V Robinson
Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins. Journal of the American Chemical Society (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Antonello Mai, Dante Rotili
Activation and inhibition of sirtuins: From bench to bedside. Medicinal research reviews (2024)
Federico Appetecchia, Emanuele Fabbrizi, Francesco Fiorentino, Sara Consalvi, Mariangela Biava, Giovanna Poce, Dante Rotili
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development. Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem (2024)
Francesco Fiorentino, Emanuele Fabbrizi, Alessia Raucci, Beatrice Noce, Rossella Fioravanti, Sergio Valente, Chantal Paolini, Ruggero De Maria, Christian Steinkühler, Paola Gallinari, Dante Rotili, Antonello Mai
Uracil- and Pyridine-Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells. ChemMedChem 19 (13) (2024)
Leonhard H Urner, Francesco Fiorentino, Denis Shutin, Joshua B Sauer, Mark T Agasid, Tarick J El-Baba, Jani Reddy Bolla, Phillip J Stansfeld, Carol V Robinson
Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins. Journal of the American Chemical Society (2024)
Federico Appetecchia, Emanuele Fabbrizi, Francesco Fiorentino, Sara Consalvi, Mariangela Biava, Giovanna Poce, Dante Rotili
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development. Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Anastasia Golovina, Eleonora Proia, Francesco Fiorentino, Maxim A Yunin, Maria Kasatkina, Nailya Zigangirova, Anna Soloveva, Elena Sysolyatina, Svetlana Ermolaeva, Roman A Novikov, Sergei Silonov, Sergei Pushkin, Milan Mladenović, Julia Isakova, Albina Belik, Maxim Nawrozkij, Dante Rotili, Rino Ragno, Roman Ivanov
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling. ACS infectious diseases (2024)
Federico Appetecchia, Emanuele Fabbrizi, Francesco Fiorentino, Sara Consalvi, Mariangela Biava, Giovanna Poce, Dante Rotili
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development. Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry (2024)
Martin Pannek, Zayan Alhalabi, Daniela Tomaselli, Martina Menna, Francesco Fiorentino, Dina Robaa, Michael Weyand, Maximilian Puhlmann, Stefano Tomassi, Federica Barreca, Marco Tafani, Elma Zaganjor, Marcia C Haigis, Wolfgang Sippl, Dante Rotili, Antonello Mai, Clemens Steegborn
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity. Journal of medicinal chemistry 67 (3) (2024)
Anastasia Golovina, Eleonora Proia, Francesco Fiorentino, Maxim A Yunin, Maria Kasatkina, Nailya Zigangirova, Anna Soloveva, Elena Sysolyatina, Svetlana Ermolaeva, Roman A Novikov, Sergei Silonov, Sergei Pushkin, Milan Mladenović, Julia Isakova, Albina Belik, Maxim Nawrozkij, Dante Rotili, Rino Ragno, Roman Ivanov
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling. ACS infectious diseases 10 (6) (2024)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D'Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Journal of medicinal chemistry (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Francesco Fiorentino, Fabrizio Carta, Dante Rotili, Antonello Mai, Claudiu T Supuran
State of the art of carbonic anhydrase activators. Future medicinal chemistry (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry (2023)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D'Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Journal of medicinal chemistry (2023)
Francesco Fiorentino, Alessio Nocentini, Dante Rotili, Claudiu T Supuran, Antonello Mai
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Emanuele Fabbrizi, Francesco Fiorentino, Vincenzo Carafa, Lucia Altucci, Antonello Mai, Dante Rotili
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection. Cells 12 (6) (2023)
Francesco Fiorentino, Martina Menna, Dante Rotili, Sergio Valente, Antonello Mai
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey. Journal of medicinal chemistry 66 (3) (2023)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Francesco Fiorentino, Carola Castiello, Antonello Mai, Dante Rotili
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5. Journal of medicinal chemistry 65 (14) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry 66 (1) (2022)
Anastasia Orekhova, Marta De Angelis, Andrea Cacciotti, Massimo Reverberi, Dante Rotili, Alessandra Giorgi, Virginia Protto, Graziana Bonincontro, Francesco Fiorentino, Victor G Zgoda, Antonello Mai, Anna Teresa Palamara, Giovanna Simonetti
Modulation of Virulence-Associated Traits in Aspergillus fumigatus by BET Inhibitor JQ1. Microorganisms 10 (11) (2022)
Francesco Fiorentino, Nicola Mautone, Martina Menna, Francesca D'Acunzo, Antonello Mai, Dante Rotili
Sirtuin modulators: past, present, and future perspectives. Future medicinal chemistry 14 (12) (2022)
Francesco Fiorentino, Marta De Angelis, Martina Menna, Annarita Rovere, Anna Maria Caccuri, Francesca D'Acunzo, Anna Teresa Palamara, Lucia Nencioni, Dante Rotili, Antonello Mai
Anti-influenza A virus activity and structure-activity relationship of a series of nitrobenzoxadiazole derivatives. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2022)
Jujun Zhou, John R Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile- Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Journal of medicinal chemistry (2022)
Francesco Fiorentino, Antonello Mai, Dante Rotili
Emerging Therapeutic Potential of SIRT6 Modulators. Journal of medicinal chemistry 64 (14) (2021)
Francesco Fiorentino, Dante Rotili, Antonello Mai, Jani Reddy Bolla, Carol V Robinson
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions. Chemical communications (Cambridge, England) 57 (82) (2021)
Francesco Fiorentino, Vincenzo Carafa, Gregorio Favale, Lucia Altucci, Antonello Mai, Dante Rotili
The Two-Faced Role of SIRT6 in Cancer. Cancers 13 (5) (2021)
Francesco Fiorentino, Joshua B Sauer, Xingyu Qiu, Robin A Corey, C Keith Cassidy, Benjamin Mynors-Wallis, Shahid Mehmood, Jani Reddy Bolla, Phillip J Stansfeld, Carol V Robinson
Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide. Nature chemical biology 17 (2) (2020)
Jani Reddy Bolla, Anna C Howes, Francesco Fiorentino, Carol V Robinson
Assembly and regulation of the chlorhexidine-specific efflux pump AceI. Proceedings of the National Academy of Sciences of the United States of America 117 (29) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Francesco Fiorentino