Giuseppina De Simone

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 27

Top Venues

Cells

Expert opinion on therapeutic patents

Biology

Journal of medicinal chemistry

National Research Council

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Research Council Jan 02 2010

Italy

Research Director

Publications

Giuseppina De Simone, Claudiu T Supuran
Anticancer drugs: where are we now? Expert opinion on therapeutic patents 34 (7) (2024)
Giuseppina De Simone, Claudiu T Supuran
Anticancer drugs: where are we now? Expert opinion on therapeutic patents (2024)
Giuseppina De Simone, Claudiu T Supuran
Anticancer drugs: where are we now? Expert opinion on therapeutic patents (2024)
Annachiara Sarnella, Ylenia Ferrara, Sandra Albanese, Daniela Omodei, Gennaro Chiappetta, Giuseppina De Simone, Claudiu T Supuran, Antonella Zannetti
Inhibition of Bone Marrow-Mesenchymal Stem Cell-Induced Carbonic Anhydrase IX Potentiates Chemotherapy Efficacy in Triple-Negative Breast Cancer Cells. Cells 12 (2) (2023)
Annachiara Sarnella, Ylenia Ferrara, Sandra Albanese, Daniela Omodei, Gennaro Chiappetta, Giuseppina De Simone, Claudiu T Supuran, Antonella Zannetti
Inhibition of Bone Marrow-Mesenchymal Stem Cell-Induced Carbonic Anhydrase IX Potentiates Chemotherapy Efficacy in Triple-Negative Breast Cancer Cells. Cells 12 (2) (2023)
Annachiara Sarnella, Ylenia Ferrara, Sandra Albanese, Daniela Omodei, Gennaro Chiappetta, Giuseppina De Simone, Claudiu T Supuran, Antonella Zannetti
Inhibition of Bone Marrow-Mesenchymal Stem Cell-Induced Carbonic Anhydrase IX Potentiates Chemotherapy Efficacy in Triple-Negative Breast Cancer Cells. Cells 12 (2) (2023)
Annachiara Sarnella, Ylenia Ferrara, Sandra Albanese, Daniela Omodei, Gennaro Chiappetta, Giuseppina De Simone, Claudiu T Supuran, Antonella Zannetti
Inhibition of Bone Marrow-Mesenchymal Stem Cell-Induced Carbonic Anhydrase IX Potentiates Chemotherapy Efficacy in Triple-Negative Breast Cancer Cells. Cells 12 (2) (2023)
Alessio Nocentini, Alessandro Bonardi, Carla Bazzicalupi, Vincenzo Alterio, Davide Esposito, Simona Maria Monti, Michael Smietana, Giuseppina De Simone, Claudiu T Supuran, Paola Gratteri, Jean-Yves Winum
6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography. Journal of medicinal chemistry (2023)
Emma Langella, Davide Esposito, Simona Maria Monti, Claudiu T Supuran, Giuseppina De Simone, Vincenzo Alterio
A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors. Biology 12 (2) (2023)
Emma Langella, Davide Esposito, Simona Maria Monti, Claudiu T Supuran, Giuseppina De Simone, Vincenzo Alterio
A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors. Biology 12 (2) (2023)
Emma Langella, Davide Esposito, Simona Maria Monti, Claudiu T Supuran, Giuseppina De Simone, Vincenzo Alterio
A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors. Biology 12 (2) (2023)
Emma Langella, Anna Di Fiore, Vincenzo Alterio, Simona Maria Monti, Giuseppina De Simone, Katia D'Ambrosio
α-CAs from Photosynthetic Organisms. International journal of molecular sciences 23 (19) (2022)
Joëlle Ayoub, Martina Buonanno, Anna Di Fiore, Giuseppina De Simone, Simona Maria Monti
Biochemical and Structural Insights into the Winged Helix Domain of P150, the Largest Subunit of the Chromatin Assembly Factor 1. International journal of molecular sciences 23 (4) (2022)
Simona Maria Monti, Giuseppina De Simone, Emma Langella
The Amazing World of IDPs in Human Diseases II. Biomolecules 12 (3) (2022)
Simona Maria Monti, Giuseppina De Simone, Emma Langella
The Amazing World of IDPs in Human Diseases. Biomolecules 11 (2) (2021)
Anna Di Fiore, Claudiu T Supuran, Andrea Scaloni, Giuseppina De Simone
Human carbonic anhydrases and post-translational modifications: a hidden world possibly affecting protein properties and functions. Journal of enzyme inhibition and medicinal chemistry 35 (1) (2021)
Murat Bozdag, Claudiu T Supuran, Davide Esposito, Andrea Ageli, Fabrizio Carta, Simona Maria Monti, Giuseppina De Simone, Vincenzo Alterio
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site. Chemical communications (Cambridge, England) 56 (59) (2021)
Anna Di Fiore, Claudiu T Supuran, Andrea Scaloni, Giuseppina De Simone
Post-translational modifications in tumor-associated carbonic anhydrases. Amino acids (2021)
Annachiara Sarnella, Giuliana D'Avino, Billy Samuel Hill, Vincenzo Alterio, Jean-Yves Winum, Claudiu T Supuran, Giuseppina De Simone, Antonella Zannetti
A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity. International journal of molecular sciences 21 (21) (2020)
Andrea Ageli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A Donald, Shoukat Dedhar, Claudiu T Supuran
Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment. Metabolites 10 (10) (2020)
Alessio Nocentini, Vincenzo Alterio, Silvia Bua, Laura Micheli, Davide Esposito, Martina Buonanno, Gianluca Bartolucci, Sameh M Osman, Zeid Abdullah ALOthman, Roberto Cirilli, Marco Pierini, Simona Maria Monti, Lorenzo Di Cesare Mannelli, Paola Gratteri, Carla Ghelardini, Giuseppina De Simone, Claudiu T Supuran
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy. Journal of medicinal chemistry 63 (10) (2020)
Katia D'Ambrosio, Simone Carradori, Stefania Cesa, Andrea Angeli, Simona M Monti, Claudiu T Supuran, Giuseppina De Simone
Catechols: a new class of carbonic anhydrase inhibitors. Chemical communications (Cambridge, England) 56 (85) (2020)
Giuseppina De Simone, Anna Di Fiore, Emanuela Truppo, Emma Langella, Daniela Vullo, Claudiu T Supuran, Simona Maria Monti
Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach. Journal of enzyme inhibition and medicinal chemistry 34 (1) (2019)
Anna Di Fiore, Daria Maria Monti, Andrea Scaloni, Giuseppina De Simone, Simona Maria Monti
Protective Role of Carbonic Anhydrases III and VII in Cellular Defense Mechanisms upon Redox Unbalance. Oxidative medicine and cellular longevity 2018 (2018)
Claudiu T Supuran, Vincenzo Alterio, Anna Di Fiore, Katia D' Ambrosio, Fabrizio Carta, Simona Maria Monti, Giuseppina De Simone
Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one. Medicinal research reviews 38 (6) (2018)
Martina Buonanno, Emma Langella, Nicola Zambrano, Mariangela Succoio, Emanuele Sasso, Vincenzo Alterio, Anna Di Fiore, Annamaria Sandomenico, Claudiu T Supuran, Andrea Scaloni, Simona Maria Monti, Giuseppina De Simone
Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements. ACS chemical biology 12 (6) (2017)
Elvira Bruno, Maria Rosa Buemi, Anna Di Fiore, Laura De Luca, Stefania Ferro, Andrea Angeli, Roberto Cirilli, Daniele Sadutto, Vincenzo Alterio, Simona Maria Monti, Claudiu T Supuran, Giuseppina De Simone, Rosaria Gitto
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. Journal of medicinal chemistry 60 (10) (2017)
Giuseppina De Simone, Ginta Pizika, Simona Maria Monti, Anna Di Fiore, Jekaterina Ivanova, Igor Vozny, Peteris Trapencieris, Raivis Žalubovskis, Claudiu T Supuran, Vincenzo Alterio
Hydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors. BioMed research international 2014 (2014)

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Publication Activity (10 Years)

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Giuseppina De Simone