Jonathan A Javitch

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 30

Top Topics

Endoplasmic Reticulum

Single Molecule

Autism Spectrum Disorder

Top Venues

Molecular psychiatry

Nature communications

Journal of the American Chemical Society

This page only lists publications with an associated author ORCID identifier.

Publications

Hao Zuo, Jinseo Park, Aurel Frangaj, Jianxiang Ye, Guanqi Lu, Jamie J Manning, Wesley B Asher, Zhengyuan Lu, Guo-Bin Hu, Liguo Wang, Joshua H Mendez, Edward T Eng, Zhening Zhang, Xin Lin, Robert Grassucci, Wayne A Hendrickson, Oliver B Clarke, Jonathan A Javitch, Arthur David Conigrave, Qing R Fan
Promiscuous G-protein activation by the calcium-sensing receptor. Nature 629 (8011) (2024)
Wei-Li Lee, Xavier Westergaard, Christopher Hwu, Jennifer Hwu, Tomas Fiala, Clay Lacefield, Umed Boltaev, Adriana M Mendieta, Lisa Lin, Mark S Sonders, Keaon R Brown, Keer He, Wesley B Asher, Jonathan A Javitch, David L Sulzer, Dalibor Sames
Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain. Journal of the American Chemical Society 146 (14) (2024)
Wei-Li Lee, Xavier Westergaard, Christopher Hwu, Jennifer Hwu, Tomas Fiala, Clay Lacefield, Umed Boltaev, Adriana M Mendieta, Lisa Lin, Mark S Sonders, Keaon R Brown, Keer He, Wesley B Asher, Jonathan A Javitch, David L Sulzer, Dalibor Sames
Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain. Journal of the American Chemical Society 146 (14) (2024)
Hao Zuo, Jinseo Park, Aurel Frangaj, Jianxiang Ye, Guanqi Lu, Jamie J Manning, Wesley B Asher, Zhengyuan Lu, Guo-Bin Hu, Liguo Wang, Joshua H Mendez, Edward T Eng, Zhening Zhang, Xin Lin, Robert Grassucci, Wayne A Hendrickson, Oliver B Clarke, Jonathan A Javitch, Arthur David Conigrave, Qing R Fan
Promiscuous G-protein activation by the calcium-sensing receptor. Nature 629 (8011) (2024)
Václav Havel, Andrew C Kruegel, Benjamin Bechand, Scot McIntosh, Leia Stallings, Alana Hodges, Madalee G Wulf, Mel Nelson, Amanda Hunkele, Michael Ansonoff, John E Pintar, Christopher Hwu, Rohini S Ople, Najah Abi-Gerges, Saheem A Zaidi, Vsevolod Katritch, Mu Yang, Jonathan A Javitch, Susruta Majumdar, Scott E Hemby, Dalibor Sames
Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models. Nature communications 15 (1) (2024)
Wei-Li Lee, Xavier Westergaard, Christopher Hwu, Jennifer Hwu, Tomas Fiala, Clay Lacefield, Umed Boltaev, Adriana M Mendieta, Lisa Lin, Mark S Sonders, Keaon R Brown, Keer He, Wesley B Asher, Jonathan A Javitch, David L Sulzer, Dalibor Sames
Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain. Journal of the American Chemical Society (2024)
Hao Zuo, Jinseo Park, Aurel Frangaj, Jianxiang Ye, Guanqi Lu, Jamie J Manning, Wesley B Asher, Zhengyuan Lu, Guo-Bin Hu, Liguo Wang, Joshua H Mendez, Edward T Eng, Zhening Zhang, Xin Lin, Robert Grassucci, Wayne A Hendrickson, Oliver B Clarke, Jonathan A Javitch, Arthur David Conigrave, Qing R Fan
Promiscuous G-protein activation by the calcium-sensing receptor. Nature (2024)
Hao Zuo, Jinseo Park, Aurel Frangaj, Jianxiang Ye, Guanqi Lu, Jamie J Manning, Wesley B Asher, Zhengyuan Lu, Guo-Bin Hu, Liguo Wang, Joshua H Mendez, Edward T Eng, Zhening Zhang, Xin Lin, Robert Grassucci, Wayne A Hendrickson, Oliver B Clarke, Jonathan A Javitch, Arthur David Conigrave, Qing R Fan
Promiscuous G-protein activation by the calcium-sensing receptor. Nature 629 (8011) (2024)
Hao Zuo, Jinseo Park, Aurel Frangaj, Jianxiang Ye, Guanqi Lu, Jamie J Manning, Wesley B Asher, Zhengyuan Lu, Guo-Bin Hu, Liguo Wang, Joshua H Mendez, Edward T Eng, Zhening Zhang, Xin Lin, Robert Grassucci, Wayne A Hendrickson, Oliver B Clarke, Jonathan A Javitch, Arthur David Conigrave, Qing R Fan
Promiscuous G-protein activation by the calcium-sensing receptor. Nature (2024)
Marie-Lise Jobin, Véronique De Smedt-Peyrusse, Fabien Ducrocq, Rim Baccouch, Asma Oummadi, Maria Hauge Pedersen, Brian Medel-Lacruz, Maria-Florencia Angelo, Sandrine Villette, Pierre Van Delft, Laetitia Fouillen, Sébastien Mongrand, Jana Selent, Tarson Tolentino-Cortez, Gabriel Barreda-Gómez, Stéphane Grégoire, Elodie Masson, Thierry Durroux, Jonathan A Javitch, Ramon Guixà-Gonzaléz, Isabel D Alves, Pierre Trifilieff
Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling. Molecular psychiatry (2023)
Daniel T Pederick, Nicole A Perry-Hauser, Huyan Meng, Zhigang He, Jonathan A Javitch, Liqun Luo
Context-dependent requirement of G protein coupling for Latrophilin-2 in target selection of hippocampal axons. eLife 12 (2023)
Marie-Lise Jobin, Véronique De Smedt-Peyrusse, Fabien Ducrocq, Rim Baccouch, Asma Oummadi, Maria Hauge Pedersen, Brian Medel-Lacruz, Maria-Florencia Angelo, Sandrine Villette, Pierre Van Delft, Laetitia Fouillen, Sébastien Mongrand, Jana Selent, Tarson Tolentino-Cortez, Gabriel Barreda-Gómez, Stéphane Grégoire, Elodie Masson, Thierry Durroux, Jonathan A Javitch, Ramon Guixà-Gonzaléz, Isabel D Alves, Pierre Trifilieff
Correction: Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling. Molecular psychiatry (2023)
Alastair C Keen, Maria Hauge Pedersen, Laura Lemel, Daniel J Scott, Meritxell Canals, Dene R Littler, Travis Beddoe, Yuki Ono, Lei Shi, Asuka Inoue, Jonathan A Javitch, J Robert Lane
OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gα z . Communications biology 5 (1) (2022)
Srijita Bhowmik, Juraj Galeta, Václav Havel, Melissa Nelson, Abdelfattah Faouzi, Benjamin Bechand, Mike Ansonoff, Tomas Fiala, Amanda Hunkele, Andrew C Kruegel, John E Pintar, Susruta Majumdar, Jonathan A Javitch, Dalibor Sames
Site selective C-H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy. Nature communications 12 (1) (2021)
Caline S Karam, Brenna L Williams, Sandra K Jones, Jonathan A Javitch
The Role of the Dopamine Transporter in the Effects of Amphetamine on Sleep and Sleep Architecture in Drosophila. Neurochemical research (2021)
Eleanor H Simpson, Eduardo F Gallo, Peter D Balsam, Jonathan A Javitch, Christoph Kellendonk
How changes in dopamine D2 receptor levels alter striatal circuit function and motivation. Molecular psychiatry (2021)
Soumen Chakraborty, Jeffrey F DiBerto, Abdelfattah Faouzi, Sarah M Bernhard, Anna M Gutridge, Steven Ramsey, Yuchen Zhou, Davide Provasi, Nitin Nuthikattu, Rahul Jilakara, Melissa N F Nelson, Wesley B Asher, Shainnel O Eans, Lisa L Wilson, Satyanarayana M Chintala, Marta Filizola, Richard M Van Rijn, Elyssa B Margolis, Bryan L Roth, Jay P McLaughlin, Tao Che, Dalibor Sames, Jonathan A Javitch, Susruta Majumdar
A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects. Journal of medicinal chemistry 64 (18) (2021)
Rajendra Uprety, Tao Che, Saheem A Zaidi, Steven G Grinnell, Balázs R Varga, Abdelfattah Faouzi, Samuel T Slocum, Abdullah Allaoa, Andras Varadi, Melissa Nelson, Sarah M Bernhard, Elizaveta Kulko, Valerie Le Rouzic, Shainnel O Eans, Chloe A Simons, Amanda Hunkele, Joan Subrath, Ying Xian Pan, Jonathan A Javitch, Jay P McLaughlin, Bryan L Roth, Gavril W Pasternak, Vsevolod Katritch, Susruta Majumdar
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site. eLife 10 (2021)
Zixiu Xiang, Xiaohui Lv, Xin Lin, Daniel E O'Brien, Molly K Altman, Dennis C Liotta, Jonathan A Javitch, Colleen M Niswender, P Jeffrey Conn
Input-specific regulation of glutamatergic synaptic transmission in the medial prefrontal cortex by mGlu2/mGlu4 receptor heterodimers. Science signaling 14 (677) (2021)
Andry Andrianarivelo, Estefani Saint-Jour, Paula Pousinha, Sebastian P Fernandez, Anna Petitbon, Veronique De Smedt-Peyrusse, Nicolas Heck, Vanesa Ortiz, Marie-Charlotte Allichon, Vincent Kappès, Sandrine Betuing, Roman Walle, Ying Zhu, Charlène Joséphine, Alexis Pierre Bemelmans, Gustavo Turecki, Naguib Mechawar, Jonathan A Javitch, Jocelyne Caboche, Pierre Trifilieff, Jacques Barik, Peter Vanhoutte
Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing. Science advances 7 (43) (2021)
Eduardo F Gallo, Julia Greenwald, Jenna Yeisley, Eric Teboul, Kelly M Martyniuk, Joseph M Villarin, Yu-Long Li, Jonathan A Javitch, Peter D Balsam, Christoph Kellendonk
Dopamine D2 receptors modulate the cholinergic pause and inhibitory learning. Molecular psychiatry (2021)
Job O de Jong, Ceyda Llapashtica, Matthieu Genestine, Kevin Strauss, Frank Provenzano, Yan Sun, Huixiang Zhu, Giuseppe P Cortese, Francesco G Brundu, Karlla W Brigatti, Barbara Corneo, Bianca Migliori, Raju Tomer, Steven A Kushner, Christoph Kellendonk, Jonathan A Javitch, Bin Xu, Sander Markx
Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder. Nature communications 12 (1) (2021)
Wesley B Asher, Peter Geggier, Michael D Holsey, Grant T Gilmore, Avik K Pati, Jozsef Meszaros, Daniel S Terry, Signe Mathiasen, Megan J Kaliszewski, Mitchell D McCauley, Alekhya Govindaraju, Zhou Zhou, Kaleeckal G Harikumar, Khuloud Jaqaman, Laurence J Miller, Adam W Smith, Scott C Blanchard, Jonathan A Javitch
Single-molecule FRET imaging of GPCR dimers in living cells. Nature methods 18 (4) (2021)
Stephen D Carter, Cheri M Hampton, Robert Langlois, Roberto Melero, Zachary J Farino, Michael J Calderon, Wen Li, Callen T Wallace, Ngoc-Han T Tran, Robert A Grassucci, Stephanie E Siegmund, Joshua G Pemberton, Travis J Morgenstern, Leanna Eisenman, Jenny I Aguilar, Nili L Greenberg, Elana S Levy, Edward Yi, William G Mitchell, William J Rice, Christoph Wigge, Jyotsna Pilli, Emily W George, Despoina Aslanoglou, Maïté Courel, Robin J Freyberg, Jonathan A Javitch, Zachary P Wills, Estela Area-Gomez, Sruti Shiva, Francesca Bartolini, Allen Volchuk, Sandra A Murray, Meir Aridor, Kenneth N Fish, Peter Walter, Tamas Balla, Deborah Fass, Sharon Grayer Wolf, Simon C Watkins, José María Carazo, George J Lu, Joachim Frank, Zachary Z Freyberg
Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Science advances 6 (14) (2020)
Avik K Pati, Ouissam El Bakouri, Steffen Jockusch, Zhou Zhou, Roger B Altman, Gabriel A Fitzgerald, Wesley B Asher, Daniel S Terry, Alessandro Borgia, Michael D Holsey, Jake E Batchelder, Chathura S Abeywickrama, Brandt Huddle, Dominic Rufa, Jonathan A Javitch, Henrik Ottosson, Scott C Blanchard
Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores. Proceedings of the National Academy of Sciences of the United States of America 117 (39) (2020)
Najeah Okashah, Shane C Wright, Kouki Kawakami, Signe Mathiasen, Joris Zhou, Sumin Lu, Jonathan A Javitch, Asuka Inoue, Michel Bouvier, Nevin A Lambert
Agonist-induced formation of unproductive receptor-G12 complexes. Proceedings of the National Academy of Sciences of the United States of America 117 (35) (2020)
Signe Mathiasen, Tiago Palmisano, Nicole A Perry-Hauser, Hannah M Stoveken, Alex Vizurraga, Dyke P McEwen, Najeah Okashah, Tobias Langenhan, Asuka Inoue, Nevin A Lambert, Gregory G Tall, Jonathan A Javitch
G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3. Nature chemical biology 16 (12) (2020)
Eduardo F Gallo, Jozsef Meszaros, Jeremy D Sherman, Muhammad O Chohan, Eric Teboul, Claire S Choi, Holly Moore, Jonathan A Javitch, Christoph Kellendonk
Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum. Nature communications 9 (1) (2018)
Prashant Donthamsetti, Eduardo F Gallo, David C Buck, Edward L Stahl, Ying Zhu, J Robert Lane, Laura M Bohn, Kim A Neve, Christoph Kellendonk, Jonathan A Javitch
Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation. Molecular psychiatry 25 (9) (2018)
Abigail M Clark, Félix Leroy, Kelly M Martyniuk, Wendy Feng, Erika McManus, Matthew R Bailey, Jonathan A Javitch, Peter D Balsam, Christoph Kellendonk
Dopamine D2 Receptors in the Paraventricular Thalamus Attenuate Cocaine Locomotor Sensitization. eNeuro 4 (5) (2017)