Koichi Takahashi

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 86

Top Topics

Acute Myeloid Leukemia

Tyrosine Kinase

Top Venues

Nature communications

Blood cancer journal

This page only lists publications with an associated author ORCID identifier.

Publications

Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Yu-Jung Tseng, Yuki Kageyama, Rebecca L Murdaugh, Ayumi Kitano, Jong Hwan Kim, Kevin A Hoegenauer, Jonathan Tiessen, Mackenzie H Smith, Hidetaka Uryu, Koichi Takahashi, James F Martin, Md Abul Hassan Samee, Daisuke Nakada
Increased iron uptake by splenic hematopoietic stem cells promotes TET2-dependent erythroid regeneration. Nature communications 15 (1) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Kumiko Chino, Asiri Saumya Ediriwickrema, Brooks A Benard, Andrew J Gentles, Ross L Levine, Niko Beerenwinkel, Koichi Takahashi, Ravindra Majeti
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Leukemia 38 (7) (2024)
Christopher P Mill, Warren C Fiskus, Courtney D D DiNardo, Patrick K Reville, John A Davis, Christine E Birdwell, Kaberi Das, Hanxi Hou, Koichi Takahashi, Lauren Flores, Xinjia Ruan, Xiaoping Su, Sanam Loghavi, Joseph D Khoury, Kapil N Bhalla
Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM). Blood cancer journal 14 (1) (2024)
Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Kumiko Chino, Asiri Saumya Ediriwickrema, Brooks A Benard, Andrew J Gentles, Ross L Levine, Niko Beerenwinkel, Koichi Takahashi, Ravindra Majeti
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Leukemia 38 (7) (2024)
Alex Bataller, Alexandre Bazinet, Courtney D D DiNardo, Abhishek Maiti, Gautam Borthakur, Naval G Daver, Nicholas James Short, Elias J Jabbour, Ghayas C Issa, Naveen Pemmaraju, Musa Yilmaz, Guillermo Montalban Bravo, Koichi Takahashi, Sanam Loghavi, Guillermo Garcia Manero, Farhad Ravandi, Hagop M Kantarjian, Tapan Mahendra Kadia
Prognostic risk signature in patients with acute myeloid leukemia treated with hypomethylating agents and venetoclax. Blood advances 8 (4) (2024)
Yu-Jung Tseng, Yuki Kageyama, Rebecca L Murdaugh, Ayumi Kitano, Jong Hwan Kim, Kevin A Hoegenauer, Jonathan Tiessen, Mackenzie H Smith, Hidetaka Uryu, Koichi Takahashi, James F Martin, Md Abul Hassan Samee, Daisuke Nakada
Increased iron uptake by splenic hematopoietic stem cells promotes TET2-dependent erythroid regeneration. Nature communications 15 (1) (2024)
Ting Zhou, Choladda V Curry, Mahsa Khanlari, Min Shi, Wei Cui, Deniz Peker, Weina Chen, Endi Wang, Juehua Gao, Qi Shen, Wei Xie, Fatima Z Jelloul, Rebecca L King, Ji Yuan, Xiaoqiong Wang, Chen Zhao, Ifeyinwa E Obiorah, Elizabeth L Courville, Eric Nomura, Sindhu Cherian, Mina L Xu, W Richard Burack, Hong-Xing Liu, Elias J Jabbour, Koichi Takahashi, Wei Wang, Sa A Wang, Joseph D Khoury, L Jeffrey Medeiros, Shimin Hu
Genetics and pathologic landscape of lineage switch of acute leukemia during therapy. Blood cancer journal 14 (1) (2024)
Guillermo Montalban Bravo, Juan Jose Rodriguez-Sevilla, David Michael Swanson, Rashmi Kanagal-Shamana, Danielle Hammond, Kelly Sharon Chien, Koiji Sasaki, Elias J Jabbour, Courtney D D DiNardo, Koichi Takahashi, Nicholas James Short, Ghayas C Issa, Naveen Pemmaraju, Tapan Mahendra Kadia, Farhad Ravandi, Naval G Daver, Gautam Borthakur, Sanam Loghavi, Sherry Pierce, Carlos Bueso-Ramos, Hagop M Kantarjian, Guillermo Garcia Manero
Influence of co-mutational patterns in disease phenotype and clinical outcomes of chronic myelomonocytic leukemia. Leukemia 38 (5) (2024)
Alex Bataller, Alexandre Bazinet, Courtney D D DiNardo, Abhishek Maiti, Gautam Borthakur, Naval G Daver, Nicholas James Short, Elias J Jabbour, Ghayas C Issa, Naveen Pemmaraju, Musa Yilmaz, Guillermo Montalban Bravo, Koichi Takahashi, Sanam Loghavi, Guillermo Garcia Manero, Farhad Ravandi, Hagop M Kantarjian, Tapan Mahendra Kadia
Prognostic risk signature in patients with acute myeloid leukemia treated with hypomethylating agents and venetoclax. Blood advances 8 (4) (2024)
Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Kumiko Chino, Asiri Saumya Ediriwickrema, Brooks A Benard, Andrew J Gentles, Ross L Levine, Niko Beerenwinkel, Koichi Takahashi, Ravindra Majeti
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Leukemia 38 (7) (2024)
Yu-Jung Tseng, Yuki Kageyama, Rebecca L Murdaugh, Ayumi Kitano, Jong Hwan Kim, Kevin A Hoegenauer, Jonathan Tiessen, Mackenzie H Smith, Hidetaka Uryu, Koichi Takahashi, James F Martin, Md Abul Hassan Samee, Daisuke Nakada
Increased iron uptake by splenic hematopoietic stem cells promotes TET2-dependent erythroid regeneration. Nature communications 15 (1) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Yu-Jung Tseng, Yuki Kageyama, Rebecca L Murdaugh, Ayumi Kitano, Jong Hwan Kim, Kevin A Hoegenauer, Jonathan Tiessen, Mackenzie H Smith, Hidetaka Uryu, Koichi Takahashi, James F Martin, Md Abul Hassan Samee, Daisuke Nakada
Increased iron uptake by splenic hematopoietic stem cells promotes TET2-dependent erythroid regeneration. Nature communications 15 (1) (2024)
Ting Zhou, Choladda V Curry, Mahsa Khanlari, Min Shi, Wei Cui, Deniz Peker, Weina Chen, Endi Wang, Juehua Gao, Qi Shen, Wei Xie, Fatima Z Jelloul, Rebecca L King, Ji Yuan, Xiaoqiong Wang, Chen Zhao, Ifeyinwa E Obiorah, Elizabeth L Courville, Eric Nomura, Sindhu Cherian, Mina L Xu, W Richard Burack, Hong-Xing Liu, Elias J Jabbour, Koichi Takahashi, Wei Wang, Sa A Wang, Joseph D Khoury, L Jeffrey Medeiros, Shimin Hu
Genetics and pathologic landscape of lineage switch of acute leukemia during therapy. Blood cancer journal 14 (1) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Yu-Jung Tseng, Yuki Kageyama, Rebecca L Murdaugh, Ayumi Kitano, Jong Hwan Kim, Kevin A Hoegenauer, Jonathan Tiessen, Mackenzie H Smith, Hidetaka Uryu, Koichi Takahashi, James F Martin, Md Abul Hassan Samee, Daisuke Nakada
Increased iron uptake by splenic hematopoietic stem cells promotes TET2-dependent erythroid regeneration. Nature communications 15 (1) (2024)
Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Deepak Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne I Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z Orlowski, Muzaffar Qazilbash, Kapil Bhalla, Simona Colla, Hagop Kantarjian, Rashmi Kanagal Shamanna, Carlos Bueso- Ramos, Daisuke Nakada, P Andrew Futreal, Elizabeth Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Clonal evolution of hematopoietic stem cells after cancer chemotherapy. bioRxiv : the preprint server for biology (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Christopher P Mill, Warren C Fiskus, Courtney D D DiNardo, Patrick K Reville, John A Davis, Christine E Birdwell, Kaberi Das, Hanxi Hou, Koichi Takahashi, Lauren Flores, Xinjia Ruan, Xiaoping Su, Sanam Loghavi, Joseph D Khoury, Kapil N Bhalla
Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM). Blood cancer journal 14 (1) (2024)
Ting Zhou, Choladda V Curry, Mahsa Khanlari, Min Shi, Wei Cui, Deniz Peker, Weina Chen, Endi Wang, Juehua Gao, Qi Shen, Wei Xie, Fatima Z Jelloul, Rebecca L King, Ji Yuan, Xiaoqiong Wang, Chen Zhao, Ifeyinwa E Obiorah, Elizabeth L Courville, Eric Nomura, Sindhu Cherian, Mina L Xu, W Richard Burack, Hong-Xing Liu, Elias J Jabbour, Koichi Takahashi, Wei Wang, Sa A Wang, Joseph D Khoury, L Jeffrey Medeiros, Shimin Hu
Genetics and pathologic landscape of lineage switch of acute leukemia during therapy. Blood cancer journal 14 (1) (2024)
Samuel Urrutia, Koichi Takahashi
Precision medicine in AML: overcoming resistance. International journal of hematology (2024)
Christopher P Mill, Warren C Fiskus, Courtney D D DiNardo, Patrick K Reville, John A Davis, Christine E Birdwell, Kaberi Das, Hanxi Hou, Koichi Takahashi, Lauren Flores, Xinjia Ruan, Xiaoping Su, Sanam Loghavi, Joseph D Khoury, Kapil N Bhalla
Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM). Blood cancer journal 14 (1) (2024)
Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Kumiko Chino, Asiri Saumya Ediriwickrema, Brooks A Benard, Andrew J Gentles, Ross L Levine, Niko Beerenwinkel, Koichi Takahashi, Ravindra Majeti
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Leukemia (2024)
Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Kumiko Chino, Asiri Saumya Ediriwickrema, Brooks A Benard, Andrew J Gentles, Ross L Levine, Niko Beerenwinkel, Koichi Takahashi, Ravindra Majeti
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Leukemia (2024)
Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Kumiko Chino, Asiri Saumya Ediriwickrema, Brooks A Benard, Andrew J Gentles, Ross L Levine, Niko Beerenwinkel, Koichi Takahashi, Ravindra Majeti
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Leukemia (2024)
Guillermo Montalban Bravo, Juan Jose Rodriguez-Sevilla, David Michael Swanson, Rashmi Kanagal-Shamana, Danielle Hammond, Kelly Sharon Chien, Koiji Sasaki, Elias J Jabbour, Courtney D D DiNardo, Koichi Takahashi, Nicholas James Short, Ghayas C Issa, Naveen Pemmaraju, Tapan Mahendra Kadia, Farhad Ravandi, Naval G Daver, Gautam Borthakur, Sanam Loghavi, Sherry Pierce, Carlos Bueso-Ramos, Hagop M Kantarjian, Guillermo Garcia Manero
Influence of co-mutational patterns in disease phenotype and clinical outcomes of chronic myelomonocytic leukemia. Leukemia (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Christopher P Mill, Warren C Fiskus, Courtney D D DiNardo, Patrick K Reville, John A Davis, Christine E Birdwell, Kaberi Das, Hanxi Hou, Koichi Takahashi, Lauren Flores, Xinjia Ruan, Xiaoping Su, Sanam Loghavi, Joseph D Khoury, Kapil N Bhalla
Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM). Blood cancer journal 14 (1) (2024)
Ting Zhou, Choladda V Curry, Mahsa Khanlari, Min Shi, Wei Cui, Deniz Peker, Weina Chen, Endi Wang, Juehua Gao, Qi Shen, Wei Xie, Fatima Z Jelloul, Rebecca L King, Ji Yuan, Xiaoqiong Wang, Chen Zhao, Ifeyinwa E Obiorah, Elizabeth L Courville, Eric Nomura, Sindhu Cherian, Mina L Xu, W Richard Burack, Hong-Xing Liu, Elias J Jabbour, Koichi Takahashi, Wei Wang, Sa A Wang, Joseph D Khoury, L Jeffrey Medeiros, Shimin Hu
Genetics and pathologic landscape of lineage switch of acute leukemia during therapy. Blood cancer journal 14 (1) (2024)
Ting Zhou, Choladda V Curry, Mahsa Khanlari, Min Shi, Wei Cui, Deniz Peker, Weina Chen, Endi Wang, Juehua Gao, Qi Shen, Wei Xie, Fatima Z Jelloul, Rebecca L King, Ji Yuan, Xiaoqiong Wang, Chen Zhao, Ifeyinwa E Obiorah, Elizabeth L Courville, Eric Nomura, Sindhu Cherian, Mina L Xu, W Richard Burack, Hong-Xing Liu, Elias J Jabbour, Koichi Takahashi, Wei Wang, Sa A Wang, Joseph D Khoury, L Jeffrey Medeiros, Shimin Hu
Genetics and pathologic landscape of lineage switch of acute leukemia during therapy. Blood cancer journal 14 (1) (2024)
Nehali Shah, Koichi Takahashi
Clonal hematopoiesis and solid tumor risk: New insights from the Women's Health Initiative. Cancer (2024)
Yu-Jung Tseng, Yuki Kageyama, Rebecca L Murdaugh, Ayumi Kitano, Jong Hwan Kim, Kevin A Hoegenauer, Jonathan Tiessen, Mackenzie H Smith, Hidetaka Uryu, Koichi Takahashi, James F Martin, Md Abul Hassan Samee, Daisuke Nakada
Increased iron uptake by splenic hematopoietic stem cells promotes TET2-dependent erythroid regeneration. Nature communications 15 (1) (2024)
Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Deepak Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne I Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z Orlowski, Muzaffar Qazilbash, Kapil Bhalla, Simona Colla, Hagop Kantarjian, Rashmi Kanagal Shamanna, Carlos Bueso- Ramos, Daisuke Nakada, P Andrew Futreal, Elizabeth Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Clonal evolution of hematopoietic stem cells after cancer chemotherapy. bioRxiv : the preprint server for biology (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Gañán-Gómez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb A Class, Lin Tan, Sergio Attanasio, Guillermo Garcia Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos E Bueso-Ramos, Marina Konopleva, Philip L Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamana, Andrea Viale, Marta Chesi, Simona Colla
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma. Nature communications 15 (1) (2024)
Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde A Miles, Robert L Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Kumiko Chino, Asiri Saumya Ediriwickrema, Brooks A Benard, Andrew J Gentles, Ross L Levine, Niko Beerenwinkel, Koichi Takahashi, Ravindra Majeti
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Leukemia 38 (7) (2024)
Ravindra Majeti, Matthew Schwede, Katharina Jahn, Jack Kuipers, Linde Miles, Robert Bowman, Troy Robinson, Ken Furudate, Hidetaka Uryu, Tomoyuki Tanaka, Kumiko Chino, Asiri Saumya Ediriwickrema, Brooks A Benard, Andrew J Gentles, Ross L Levine, Niko Beerenwinkel, Koichi Takahashi
Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity. Research square (2023)
Curtis A Lachowiez, Sanam Loghavi, Zhihong Zeng, Tomoyuki Tanaka, Yi June Kim, Hidetaka Uryu, Sven Turkalj, Niels Asger Jakobsen, Marlise R Luskin, Dzifa Yawa Duose, Rebecca S Slack Tidwell, Nicholas James Short, Gautam Borthakur, Tapan Mahendra Kadia, Lucia Masarova, George D Tippett, Prithviraj Bose, Elias J Jabbour, Farhad Ravandi, Naval G Daver, Guillermo Garcia Manero, Hagop M Kantarjian, Jacqueline S Garcia, Paresh Vyas, Koichi Takahashi, Marina Y Konopleva, Courtney D D DiNardo
A phase Ib/II study of ivosidenib with venetoclax +/- azacitidine in IDH1-mutated myeloid malignancies. Blood cancer discovery (2023)
Etienne Sollier, Jack Kuipers, Koichi Takahashi, Niko Beerenwinkel, Katharina Jahn
COMPASS: joint copy number and mutation phylogeny reconstruction from amplicon single-cell sequencing data. Nature communications 14 (1) (2023)
Danielle Hammond, Sanam Loghavi, Sa A Wang, Marina Y Konopleva, Tapan Mahendra Kadia, Naval G Daver, Maro Ohanian, Ghayas C Issa, Yesid Alvarado, Nicholas James Short, Koji Sasaki, Naveen Pemmaraju, Guillermo Montalban-Bravo, Curtis A Lachowiez, Abhishek Maiti, Guillermo Garcia Manero, Elias J Jabbour, Gautam Borthakur, Farhad Ravandi, Koichi Takahashi, Sherry R Pierce, Hagop M Kantarjian, Courtney D D DiNardo
Response patterns and impact of MRD in patients with IDH1/2-mutated AML treated with venetoclax and hypomethylating agents. Blood cancer journal 13 (1) (2023)
Warren C Fiskus, Christopher P Mill, Christine Birdwell, John A Davis, Kaberi Das, Steffen Boettcher, Tapan Mahendra Kadia, Courtney D D DiNardo, Koichi Takahashi, Sanam Loghavi, Michael J Soth, Tim Heffernan, Gerard M McGeehan, Xinjia Ruan, Xiaoping Su, Christopher R Vakoc, Naval G Daver, Kapil N Bhalla
Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1. Blood cancer journal 13 (1) (2023)
Raghav Ramabadran, Jarey H Wang, Jaime M Reyes, Anna G Guzman, Sinjini Gupta, Carina Rosas, Lorenzo Brunetti, Michael C Gundry, Ayala Tovy, Hali Long, Tianpeng Gu, Sean M Cullen, Siddhartha Tyagi, Danielle Rux, Jean J Kim, Steven M Kornblau, Michael Kyba, Fabio Stossi, Rachel E Rau, Koichi Takahashi, Thomas F Westbrook, Margaret A Goodell
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells. Nature cell biology (2023)
Linda Zhang, Joanne I Hsu, Etienne D Braekeleer, Chun-Wei Chen, Tajhal D Patel, Hidetaka Urya, Anna G Guzman, Alejandra G Martell, Sarah M Waldvogel, Ayala Tovy, Elsa Callen, Rebecca Murdaugh, Rosemary Richard, Sandra Jansen, Lisenka E L M Vissers, Bert B A de Vries, Andre Nussenzweig, Shixia Huang, Cristian Coarfa, Jamie N Anastas, Koichi Takahashi, George S Vassiliou, Margaret A Goodell
SOD1 is a synthetic lethal target in PPM1D -mutant leukemia cells. bioRxiv : the preprint server for biology (2023)
Christopher P Mill, Warren C Fiskus, Kaberi Das, John A Davis, Christine E Birdwell, Tapan Mahendra Kadia, Courtney D D DiNardo, Naval G Daver, Koichi Takahashi, Koiji Sasaki, Gerard M McGeehan, Xinjia Ruan, Xiaoping Su, Sanam Loghavi, Hagop Kantarjian, Kapil N Bhalla
Causal linkage of presence of mutant NPM1 to efficacy of novel therapeutic agents against AML cells with mutant NPM1. Leukemia (2023)
Guillermo Montalban Bravo, Feiyang Ma, Natthakan Thongon, Hui Yang, Irene Ganan- Gomez, Juanjo Jose Rodriguez-Sevilla, Vera Adema, Bethany Wildeman, Pamela Lockyer, Yi June Kim, Tomoyuki Tanaka, Faezeh Darbaniyan, Shivam Pancholy, Geoffrey Zhang, Gheath Al-Atrash, Karen Dwyer, Koichi Takahashi, Guillermo Garcia-Manero, Hagop Kantarjian, Simona Colla
Targeting MCL1-driven anti-apoptotic pathways to overcome hypomethylating agent resistance in RAS -mutated chronic myelomonocytic leukemia. bioRxiv : the preprint server for biology (2023)
Sung-Eun Lee, Feng Wang, Maison Grefe, Abel Trujillo-Ocampo, Wilfredo Ruiz-Vasquez, Koichi Takahashi, Hussein A Abbas, Pamella Borges, Dinler Amaral Antunes, Gheath Al-Atrash, Naval G Daver, Jeffrey J Molldrem, P Andrew Futreal, Guillermo Garcia Manero, Jim S Im
Immunologic Predictors for Clinical Responses during Immune Checkpoint Blockade in Patients with Myelodysplastic Syndromes. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Jayastu Senapati, Elias J Jabbour, Marina Y Konopleva, Nicholas James Short, Guillin Tang, Naval G Daver, Partow Kebriaei, Tapan Mahendra Kadia, Naveen Pemmaraju, Koichi Takahashi, Courtney D D DiNardo, Koiji Sasaki, Gautam Borthakur, Beenu Thakral, Rashmi Kanagal-Shamana, Keyur Pravinchandra Patel, Farhad Ravandi, Kathryn G Roberts, Charles G Mullighan, Hagop M Kantarjian, Nitin Jain
Philadelphia-Like Genetic Rearrangements in Adults With B-Cell ALL: Refractoriness to Chemotherapy and Response to Tyrosine Kinase Inhibitor in ABL Class Rearrangements. JCO precision oncology 7 (2023)
Siba El Hussein, Courtney D DiNardo, Koichi Takahashi, Joseph D Khoury, Hong Fang, Ken Furudate, Kirill A Lyapichev, Sofia Garces, Rashmi Kanagal-Shamana, Chi Young Ok, Keyur Pravinchandra Patel, Mark J Routbort, Farhad Ravandi, L Jeffrey Medeiros, Sa A Wang, Sanam Loghavi
Acquired WT1 mutations contribute to relapse of NPM1-mutated acute myeloid leukemia following allogeneic hematopoietic stem cell transplant. Bone marrow transplantation 57 (3) (2022)
Koichi Takahashi
Untangling the Relationship Between Clonal Hematopoiesis and Ovarian Cancer Therapies. Journal of the National Cancer Institute 114 (4) (2022)
Warren C Fiskus, Steffen Boettcher, Naval G Daver, Christopher P Mill, Koiji Sasaki, Christine E Birdwell, John A Davis, Koichi Takahashi, Tapan Mahendra Kadia, Courtney D DiNardo, Qi Jin, Yuan Qi, Xiaoping Su, Gerard M McGeehan, Joseph D Khoury, Benjamin L Ebert, Kapil N Bhalla
Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c). Blood cancer journal 12 (1) (2022)
Mahsa Khanlari, Cheng Cameron Yin, Koichi Takahashi, Curtis A Lachowiez, Guillin Tang, Sanam Loghavi, Ismael Bah, Wei Wang, Sergej Konoplev, L Jeffrey Medeiros, Naveen Pemmaraju, Joseph D Khoury, Sa A Wang
Bone marrow clonal hematopoiesis is highly prevalent in blastic plasmacytoid dendritic cell neoplasm and frequently sharing a clonal origin in elderly patients. Leukemia 36 (5) (2022)
Tapan Mahendra Kadia, Patrick K Reville, Xuemei Wang, Caitlin R Rausch, Gautam Borthakur, Naveen Pemmaraju, Naval G Daver, Courtney D DiNardo, Koiji Sasaki, Ghayas C Issa, Maro Ohanian DO, Guillermo Montalban-Bravo, Nicholas James Short, Nitin Jain, Alessandra Ferrajoli, Kapil N Bhalla, Elias J Jabbour, Koichi Takahashi, Rashmi Malla, Kelly Quagliato, Rashmi Kanagal-Shamana, Sairah A Ahmed, Michael Andreeff, Guillermo Garcia Manero, Marina Y Konopleva, Farhad Ravandi, Hagop M Kantarjian
Phase II Study of Venetoclax Added to Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (33) (2022)
Sangeetha Venugopal, Koichi Takahashi, Naval G Daver, Abhishek Maiti, Gautam Borthakur, Sanam Loghavi, Nicholas James Short, Maro Ohanian, Lucia Masarova, Ghayas C Issa, Xuemei Wang, Bueso-Ramos Carlos, Musa Ylimaz, Tapan Mahendra Kadia, Michael Andreeff, Farhad Ravandi, Marina Y Konopleva, Hagop M Kantarjian, Courtney D D DiNardo
Efficacy and safety of enasidenib and azacitidine combination in patients with IDH2 mutated acute myeloid leukemia and not eligible for intensive chemotherapy. Blood cancer journal 12 (1) (2022)
Kumiko Chino, Hagop M Kantarjian, Nicholas James Short, Feng Wang, Ken Furudate, Hidetaka Uryu, Rebecca Garris, Nitin Jain, Koiji Sasaki, Farhad Ravandi, Marina Y Konopleva, Guillermo Garcia Manero, Latasha Little, Curtis Gumbs, Li Zhao, P Andrew Futreal, Koichi Takahashi, Elias J Jabbour
Genetic correlates in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with Hyper-CVAD plus dasatinib or ponatinib. Leukemia 36 (5) (2022)
Natalia Baran, Alessia Lodi, Yogesh Dhungana, Shelley Herbrich, Meghan E Collins, Shannon Sweeney, Renu Pandey, Anna Skwarska, Shraddha Patel, Mathieu Tremblay, Vinitha Mary Kuruvilla, Antonio Cavazos, Mecit Kaplan, Marc O Warmoes, Diogo Troggian Veiga, Ken Furudate, Shanti Rojas-Sutterin, Andre Haman, Yves Gareau, Anne Marinier, Helen Ma, Karine Harutyunyan, May Daher, Luciana Melo Garcia, Gheath Al-Atrash, Sujan Piya, Vivian Ruvolo, Wentao Yang, Sriram Saravanan Shanmugavelandy, Ningping Feng, Jason Gay, Di Du, Jun J Yang, Fieke W Hoff, Marcin Mikołaj Kamiński, Katarzyna Tomczak, Richard Eric Davis, Daniel Herranz, Adolfo A Ferrando, Elias J Jabbour, M Emilia Di Francesco, David Trent Teachey, Terzah M Horton, Steven Mitchell Kornblau, Katayoun Rezvani, Guy Sauvageau, Mihai Gagea, Michael Andreeff, Koichi Takahashi, Joseph R Marszalek, Philip L Lorenzi, Jiyang Yu, Stefano Tiziani, Trang Hoang, Marina Y Konopleva
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nature communications 13 (1) (2022)
Warren C Fiskus, Naval G Daver, Steffen Boettcher, Christopher P Mill, Koiji Sasaki, Christine E Birdwell, John A Davis, Kaberi Das, Koichi Takahashi, Tapan Mahendra Kadia, Courtney D D DiNardo, Francis Burrows, Sanam Loghavi, Joseph D Khoury, Benjamin L Ebert, Kapil N Bhalla
Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1. Leukemia 36 (11) (2022)
Musa Ylimaz, Hagop M Kantarjian, Nicholas James Short, Patrick K Reville, Marina Y Konopleva, Tapan Mahendra Kadia, Courtney D D DiNardo, Gautam Borthakur, Naveen Pemmaraju, Abhishek Maiti, Elias J Jabbour, Nitin Jain, Ghayas C Issa, Koichi Takahashi, Koiji Sasaki, Maro Ohanian, Sherry Pierce, Guillin Tang, Sanam Loghavi, Keyur Pravinchandra Patel, Sa A Wang, Guillermo Garcia Manero, Michael Andreeff, Farhad Ravandi, Naval G Daver
Hypomethylating agent and venetoclax with FLT3 inhibitor "triplet" therapy in older/unfit patients with FLT3 mutated AML. Blood cancer journal 12 (5) (2022)
Neeraj Y Saini, David M Swoboda, Uri Greenbaum, Junsheng Ma, Romil D Patel, Kartik Devashish, Kaberi Das, Mark R Tanner, Paolo Strati, Ranjit Nair, Luis Fayad, Sairah A Ahmed, Hun Ju Lee, Swaminathan P Iyer, Raphael E Steiner, Nitin Jain, Loretta Nastoupil, Sanam Loghavi, Guilin Tang, Roland L Bassett, Preetesh Jain, Michael L Wang, Jason R Westin, Michael R Green, David A Sallman, Eric Padron, Marco L Davila, Frederick L Locke, Richard E Champlin, Guillermo Garcia-Manero, Elizabeth J Shpall, Partow Kebriaei, Christopher R Flowers, Michael D Jain, Feng Wang, Andrew P Futreal, Nancy Gillis, Sattva S Neelapu, Koichi Takahashi
Clonal Hematopoiesis Is Associated with Increased Risk of Severe Neurotoxicity in Axicabtagene Ciloleucel Therapy of Large B-Cell Lymphoma. Blood cancer discovery 3 (5) (2022)
Irene Gañán-Gómez, Hui Yang, Feiyang Ma, Guillermo Montalban-Bravo, Natthakan Thongon, Valentina Marchica, Guillaume Richard-Carpentier, Kelly Sharon Chien, Ganiraju C Manyam, Feng Wang, Ana Alfonso, Shuaitong Chen, Caleb A Class, Rashmi Kanagal-Shamana, Justin P Ingram, Yamini Ogoti, Ashley Rose, Sanam Loghavi, Pamela Lockyer, Benedetta Cambo, Muharrem Muftuoglu, Sarah M Schneider, Vera Adema, Michael D McLellan, John Garza, Matteo Marchesini, Nicola Giuliani, Matteo Pellegrini, Jing Wang, Jason R Walker, Ziyi Li, Koichi Takahashi, Joel D Leverson, Carlos Bueso-Ramos, Michael Andreeff, Karen Clise-Dwyer, Guillermo Garcia Manero, Simona Colla
Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy. Nature medicine 28 (3) (2022)
Betül Oran, Richard E Champlin, Feng Wang, Tomoyuki Tanaka, Rima M Saliba, Gheath Al-Atrash, Guillermo Garcia Manero, Hagop M Kantarjian, Kai Cao, Elizabeth J Shpall, Amin M Alousi, Rohtesh S Mehta, Uday R Popat, P Andrew Futreal, Koichi Takahashi
Correction to: Donor clonal hematopoiesis increases risk of acute graft versus host disease after matched sibling transplantation. Leukemia (2021)
Warren C Fiskus, Christopher P Mill, Behnam Nabet, Dimuthu Perera, Christine Birdwell, Taghi Manshouri, Bernardo Lara, Tapan Mahendra Kadia, Courtney D D DiNardo, Koichi Takahashi, Naval G Daver, Prithviraj Bose, Lucia Masarova, Naveen Pemmaraju, Steven Mitchell Kornblau, Gautam Borthakur, Guillermo Montalban-Bravo, Guillermo Garcia Manero, Sunil Sharma, Matthew Stubbs, Xiaoping Su, Michael R Green, Cristian Coarfa, Srdan Verstovsek, Joseph D Khoury, Christopher R Vakoc, Kapil N Bhalla
Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells. Blood cancer journal 11 (5) (2021)
Xiangguo Shi, Yajian Jiang, Ayumi Kitano, Tianyuan Hu, Rebecca L Murdaugh, Yuan Li, Kevin A Hoegenauer, Rui Chen, Koichi Takahashi, Daisuke Nakada
Nuclear NAD+ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells. Science advances 7 (30) (2021)
Courtney D D DiNardo, Curtis A Lachowiez, Koichi Takahashi, Sanam Loghavi, Lianchun Xiao, Tapan Mahendra Kadia, Naval G Daver, Maria Adeoti, Nicholas James Short, Koiji Sasaki, Sa Wang, Gautam Borthakur, Ghayas Issa, Abhishek Maiti, Yesid Alvarado, Naveen Pemmaraju, Guillermo Montalban Bravo, Lucia Masarova, Musa Yilmaz, Nitin Jain, Michael Andreeff, Elias J Jabbour, Guillermo Garcia Manero, Steven Mitchell Kornblau, Farhad Ravandi, Marina Y Konopleva, Hagop M Kantarjian
Venetoclax Combined With FLAG-IDA Induction and Consolidation in Newly Diagnosed and Relapsed or Refractory Acute Myeloid Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39 (25) (2021)
Kiyomi Morita, Feng Wang, Katharina Jahn, Tianyuan Hu, Tomoyuki Tanaka, Yuya Sasaki, Jack Kuipers, Sanam Loghavi, Sa A Wang, Yuanqing Yan, Ken Furudate, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika Thompson, Keyur P Patel, Carlos E Bueso-Ramos, Courtney D D DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jorge E Cortes, Kapil Bhalla, Guillermo Garcia Manero, Hagop Kantarjian, Marina Y Konopleva, Daisuke Nakada, Nicholas Navin, Niko Beerenwinkel, P Andrew Futreal, Koichi Takahashi
Author Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics. Nature communications 12 (1) (2021)
Feng Wang, Kiyomi Morita, Courtney D D DiNardo, Ken Furudate, Tomoyuki Tanaka, Yuanqing Yan, Keyur P Patel, Kyle J MacBeth, Bin Wu, Guowen Liu, Mark Frattini, Jairo A Matthews, Latasha D Little, Curtis Gumbs, Xingzhi Song, Jianhua Zhang, Erika J Thompson, Tapan M Kadia, Guillermo Garcia Manero, Elias Jabbour, Farhad Ravandi, Kapil N Bhalla, Marina Y Konopleva, Hagop M Kantarjian, P Andrew Futreal, Koichi Takahashi
Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia. Nature communications 12 (1) (2021)
Hussein A Abbas, Dapeng Hao, Katarzyna Tomczak, Praveen Barrodia, Jin Seon Im, Patrick K Reville, Zoe Alaniz, Wei Wang, Ruiping Wang, Feng Wang, Gheath Al-Atrash, Koichi Takahashi, Jing Ning, Maomao Ding, Hannah C Beird, Jairo T Mathews, Latasha Little, Jianhua Zhang, Sreyashi Basu, Marina Y Konopleva, Mario L Marques-Piubelli, Luisa Maren Solis Soto, Edwin Roger Parra Cuentes, Wei Lu, Auriole Tamegnon, Guillermo Garcia Manero, Michael R Green, Padmanee Sharma, James P Allison, Steven Mitchell Kornblau, Kunal Rai, Linghua Wang, Naval Daver, P Andrew Futreal
Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy. Nature communications 12 (1) (2021)
Jack Kuipers, Ariane L Moore, Katharina Jahn, Peter Schraml, Feng Wang, Kiyomi Morita, P Andrew Futreal, Koichi Takahashi, Christian Beisel, Holger Moch, Niko Beerenwinkel
Statistical tests for intra-tumour clonal co-occurrence and exclusivity. PLoS computational biology 17 (12) (2021)
Abhishek Maiti, Courtney D D DiNardo, Naval G Daver, Caitlin R Rausch, Farhad Ravandi, Tapan Mahendra Kadia, Naveen Pemmaraju, Gautam Borthakur, Prithviraj Bose, Ghayas C Issa, Nicholas James Short, Musa Yilmaz, Guillermo Montalban-Bravo, Alessandra Ferrajoli, Elias J Jabbour, Nitin Jain, Maro Ohanian, Koichi Takahashi, Phillip A Thompson, Sanam Loghavi, Kathryn S Montalbano, Sherry Pierce, William G Wierda, Hagop M Kantarjian, Marina Y Konopleva
Triplet therapy with venetoclax, FLT3 inhibitor and decitabine for FLT3-mutated acute myeloid leukemia. Blood cancer journal 11 (2) (2021)
Nitin Jain, Phillip A Thompson, Jan A Burger, Alessandra Ferrajoli, Koichi Takahashi, Zeev E Estrov, Gautam Borthakur, Prithviraj Bose, Tapan Mahendra Kadia, Naveen Pemmaraju, Koiji Sasaki, Marina Y Konopleva, Elias J Jabbour, Naveen Garg, Xuemei Wang, Rashmi Kanagal-Shamana, Keyur Pravinchandra Patel, Wei Wang, Jeffrey Jorgensen, Sa Wang, Wanda Lopez, Ana Ayala, William Plunkett, Varsha Gandhi, Hagop M Kantarjian, Susan O'Brien, Michael Keating, William G Wierda
Ibrutinib, fludarabine, cyclophosphamide, and obinutuzumab (iFCG) regimen for chronic lymphocytic leukemia (CLL) with mutated IGHV and without TP53 aberrations. Leukemia 35 (12) (2021)
Betül Oran, Richard E Champlin, Feng Wang, Tomoyuki Tanaka, Rima M Saliba, Gheath Al-Atrash, Guillermo Garcia Manero, Hagop M Kantarjian, Kai Cao, Elizabeth J Shpall, Amin M Alousi, Rohtesh S Mehta, Uday R Popat, P Andrew Futreal, Koichi Takahashi
Donor clonal hematopoiesis increases risk of acute graft versus host disease after matched sibling transplantation. Leukemia (2021)
Wei Wang, Hannah C Beird, Caleb Jonathan Kroll, Shimin Hu, Carlos E Bueso-Ramos, Hong Fang, Guilin Tang, Zhenya Tang, Feng Wang, Koichi Takahashi, M James You, Joseph D Khoury, L Jeffrey Medeiros, P Andrew Futreal
T(6;14)(q25;q32) involves BCL11B and is highly associated with mixed-phenotype acute leukemia, T/myeloid. Leukemia 34 (9) (2020)
Kiyomi Morita, Feng Wang, Katharina Jahn, Tianyuan Hu, Tomoyuki Tanaka, Yuya Sasaki, Jack Kuipers, Sanam Loghavi, Sa A Wang, Yuanqing Yan, Ken Furudate, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika Thompson, Keyur P Patel, Carlos E Bueso-Ramos, Courtney D D DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jorge E Cortes, Kapil Bhalla, Guillermo Garcia Manero, Hagop Kantarjian, Marina Y Konopleva, Daisuke Nakada, Nicholas Navin, Niko Beerenwinkel, P Andrew Futreal, Koichi Takahashi
Publisher Correction: Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics. Nature communications 11 (1) (2020)
Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Koji Sasaki, Keyur Patel, Irene Ganan-Gomez, Elias Jabbour, Tapan Mahendra Kadia, Farhad Ravandi, Courtney DiNardo, Gautham Borthakur, Koichi Takahashi, Marina Konopleva, Rami S Komrokji, Amy DeZern, Teodora Kuzmanovic, Jaroslaw Maciejewski, Sherry Pierce, Simona Colla, Mikkael A Sekeres, Hagop Kantarjian, Carlos Bueso-Ramos, Guillermo Garcia-Manero
NPM1 mutations define a specific subgroup of MDS and MDS/MPN patients with favorable outcomes with intensive chemotherapy. Blood advances 3 (6) (2020)
Guillermo Garcia-Manero, Yasmin Abaza, Koichi Takahashi, Bruno C Medeiros, Martha Arellano, Samer K Khaled, Mrinal Patnaik, Olatoyosi Odenike, Hamid Sayar, Mohan Tummala, Prapti Patel, Lori Maness-Harris, Robert Stuart, Elie Traer, Kasra Karamlou, Abdulraheem Yacoub, Richard Ghalie, Ruben Giorgino, Ehab Atallah
Pracinostat plus azacitidine in older patients with newly diagnosed acute myeloid leukemia: results of a phase 2 study. Blood advances 3 (4) (2020)
Kiyomi Morita, Feng Wang, Katharina Jahn, Tianyuan Hu, Tomoyuki Tanaka, Yuya Sasaki, Jack Kuipers, Sanam Loghavi, Sa A Wang, Yuanqing Yan, Ken Furudate, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika Thompson, Keyur P Patel, Carlos E Bueso-Ramos, Courtney D D DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jorge E Cortes, Kapil Bhalla, Guillermo Garcia Manero, Hagop Kantarjian, Marina Y Konopleva, Daisuke Nakada, Nicholas Navin, Niko Beerenwinkel, P Andrew Futreal, Koichi Takahashi
Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics. Nature communications 11 (1) (2020)
Ghayas C Issa, Hagop M Kantarjian, Lianchun Xiao, Jing Ning, Yesid Alvarado, Gautam Borthakur, Naval Daver, Courtney D DiNardo, Elias Jabbour, Prithviraj Bose, Nitin Jain, Tapan Mahendra Kadia, Kiran Naqvi, Naveen Pemmaraju, Koichi Takahashi, Srdan Verstovsek, Micheal Andreeff, Steven Mitchell Kornblau, Zeev Estrov, Alessandra Ferrajoli, Guillermo Garcia-Manero, Maro Ohanian, William G Wierda, Farhad Ravandi, Jorge E Cortes
Phase II trial of CPX-351 in patients with acute myeloid leukemia at high risk for induction mortality. Leukemia 34 (11) (2020)
Kelly L Bolton, Ryan N Ptashkin, Teng Gao, Lior Braunstein, Sean M Devlin, Daniel Kelly, Minal Patel, Antonin Berthon, Aijazuddin Syed, Mariko Yabe, Catherine C Coombs, Nicole M Caltabellotta, Mike Walsh, Kenneth Offit, Zsofia Stadler, Diana Mandelker, Jessica Schulman, Akshar Patel, John Philip, Elsa Bernard, Gunes Gundem, Juan E Arango Ossa, Max Fine Levine, Juan S Medina Martinez, Noushin Farnoud, Dominik Glodzik, Sonya Li, Mark E Robson, Choonsik Lee, Paul David Peter Pharoah, Konrad H Stopsack, Barbara Spitzer, Simon Mantha, James A Fagin, Laura Boucai, Christopher J Gibson, Benjamin L Ebert, Andrew L Young, Todd Druley, Koichi Takahashi, Nancy Gillis, Markus Ball, Eric Padron, David M Hyman, Jose Baselga, Larry Norton, Stuart Gardos, Virginia M Klimek, Howard Scher, Dean Bajorin, Eder Paraiso, Ryma Benayed, Maria E Arcila, Marc Ladanyi, David B Solit, Michael F Berger, Martin Tallman, Montserrat Garcia-Closas, Nilanjan Chatterjee, Luis A Diaz, Ross L Levine, Lindsay M Morton, Ahmet Zehir, Elli Papaemmanuil
Cancer therapy shapes the fitness landscape of clonal hematopoiesis. Nature genetics 52 (11) (2020)
Mahesh Swaminathan, Sarah A Bannon, Mark Routbort, Kiran Naqvi, Tapan M Kadia, Koichi Takahashi, Yesid Alvarado, Farhad Ravandi-Kashani, Keyur P Patel, Richard Champlin, Hagop Kantarjian, Louise Strong, Courtney D DiNardo
Hematologic malignancies and Li-Fraumeni syndrome. Cold Spring Harbor molecular case studies 5 (1) (2019)
Koichi Takahashi
Ups and downs of CHIP. Blood 131 (16) (2019)
Koichi Takahashi, Feng Wang, Kiyomi Morita, Yuanqing Yan, Peter Hu, Pei Zhao, Abdallah Abou Zhar, Chang Jiun Wu, Curtis Gumbs, Latasha Little, Samantha Tippen, Rebecca Thornton, Marcus Coyle, Marisela Mendoza, Erika Thompson, Jianhua Zhang, Courtney D DiNardo, Nitin Jain, Farhad Ravandi, Jorge E Cortes, Guillermo Garcia-Manero, Steven Kornblau, Michael Andreeff, Elias Jabbour, Carlos Bueso-Ramos, Akifumi Takaori-Kondo, Marina Konopleva, Keyur Patel, Hagop Kantarjian, P Andrew Futreal
Integrative genomic analysis of adult mixed phenotype acute leukemia delineates lineage associated molecular subtypes. Nature communications 9 (1) (2018)
Lucia Masarova, Srdan Verstovsek, Juliana E Hidalgo-Lopez, Naveen Pemmaraju, Prithviraj Bose, Zeev Estrov, Elias J Jabbour, Farhad Ravandi-Kashani, Koichi Takahashi, Jorge E Cortes, Jing Ning, Maro Ohanian, Yesid Alvarado, Lingsha Zhou, Sherry Pierce, Romany Gergis, Keyur P Patel, Rajyalakshmi Luthra, Tapan M Kadia, Courtney D DiNardo, Gautam Borthakur, Kapil Bhalla, Guillermo Garcia-Manero, Carlos E Bueso-Ramos, Hagop M Kantarjian, Naval Daver
A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis. Blood 132 (16) (2018)
Koichi Takahashi, Boyu Hu, Feng Wang, Yuanqing Yan, Ekaterina Kim, Candida Vitale, Keyur P Patel, Paolo Strati, Curtis Gumbs, Latasha Little, Samantha Tippen, Xingzhi Song, Jianhua Zhang, Nitin Jain, Philip Thompson, Guillermo Garcia-Manero, Hagop Kantarjian, Zeev Estrov, Kim-Anh Do, Michael Keating, Jan A Burger, William G Wierda, P Andrew Futreal, Alessandra Ferrajoli
Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide. Blood 131 (16) (2018)
Koichi Takahashi, Feng Wang, Hagop Kantarjian, Xingzhi Song, Keyur Patel, Sattva Neelapu, Curtis Gumbs, Latasha Little, Samantha Tippen, Rebecca Thornton, Courtney D DiNardo, Farhad Ravandi, Carlos Bueso-Ramos, Jianhua Zhang, Xifeng Wu, Guillermo Garcia-Manero, P Andrew Futreal
Copy number alterations detected as clonal hematopoiesis of indeterminate potential. Blood advances 1 (15) (2017)