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Marco Ruella

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Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 23

Top Venues

Nature medicine

Blood

Journal for immunotherapy of cancer

Nature communications

University of Pennsylvania

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pennsylvania Dec 1o 2012

United States

Assistant Professo :: Medicine

Publications

Raymond Hall Yip Louie, Curtis Cai, Jerome Samir, Mandeep Singh, Ira W Deveson, James M Ferguson, Timothy G Amos, Helen Marie McGuire, Kavitha Gowrishankar, Thiruni Adikari, Robert Balderas, Martina Bonomi, Marco Ruella, David C Bishop, David Gottlieb, Emily Blyth, Kenneth Micklethwaite, Fabio Luciani
CAR + and CAR - T cells share a differentiation trajectory into an NK-like subset after CD19 CAR T cell infusion in patients with B cell malignancies. Nature communications 14 (1) (2023)
Kristin G Anderson, David A Braun, Aitziber Buque, Sarah B Gitto, Jennifer L Guerriero, Brendan L Horton, Bridget P Keenan, Teresa S Kim, Abigail Overacre-Delgoffe, Marco Ruella, Todd A Triplett, Omkara Veeranki, Vivek Verma, Fan Zhang
Leveraging immune resistance archetypes in solid cancer to inform next-generation anticancer therapies. Journal for immunotherapy of cancer 11 (6) (2023)
Yong Gu Lee, Nicholas Yang, Inkook Chun, Patrizia Porazzi, Alberto Carturan, Luca Paruzzo, Christopher Tor Sauter, Puneeth Guruprasad, Raymone Pajarillo, Marco Ruella
Apoptosis: a Janus bifrons in T-cell immunotherapy. Journal for immunotherapy of cancer 11 (4) (2023)
Nan Zhou, Jaewoo Choi, Grant Peter Grothusen, Bang-Jin Kim, Diqiu Ren, Zhendong Cao, Qinglan Li, Yiman Liu, Arati A Inamdar, Thomas Beer, Hsin-Yao Tang, Eric Perkey, Ivan P Maillard, Roberto Bonasio, Junwei Shi, Marco Ruella, Liling Wan, Luca Busino
DLBCL associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemo-resistance. Blood (2023)
Zhiwei Ang, Luca Paruzzo, Katharina E Hayer, Carolin Schmidt, Manuel Torres-Diz, Feng Xu, Urvi Zankharia, Yunlin Zhang, Samantha Soldan, Sisi Zheng, Catherine D Falkenstein, Joseph P Loftus, Scarlett Y Yang, Mukta Asnani, Patricia King Sainos, Vinodh Pillai, Emeline Chong, Marilyn M Li, Sarah K Tasian, Yoseph Barash, Paul M Lieberman, Marco Ruella, Stephen J Schuster, Andrei Thomas-Tikhonenko
Alternative splicing of its 5'-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. bioRxiv : the preprint server for biology (2023)
Zhiwei Ang, Luca Paruzzo, Katharina E Hayer, Carolin Schmidt, Manuel Torres-Diz, Feng Xu, Urvi Zankharia, Yunlin Zhang, Samantha S Soldan, Sisi Zheng, Catherine D Falkenstein, Joseph Patrick Loftus, Scarlett Y Yang, Mukta Asnani, Patricia King Sainos, Vinodh Pillai, Emeline R Chong, Marilyn M Li, Sarah K Tasian, Yoseph Barash, Paul M Lieberman, Marco Ruella, Stephen J Schuster, Andrei Thomas-Tikhonenko
Alternative splicing of its 5' UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. Blood (2023)
Marco Ruella, Felix Korell, Patrizia Porazzi, Marcela V Maus
Mechanisms of resistance to chimeric antigen receptor-T cells in haematological malignancies. Nature reviews. Drug discovery (2023)
Yong Gu Lee, Puneeth Guruprasad, Guido Ghilardi, Raymone Pajarillo, Christopher Tor Sauter, Ruchi Patel, Hatcher J Ballard, Seok Jae Hong, Inkook Chun, Nicholas Yang, Kimberly V Amelsberg, Katherine D Cummins, Jakub Svoboda, Saar I Gill, Elise A Chong, Khrystyna North, Sarah E Church, Joseph A Fraietta, Wan-Jung Chang, Simon F Lacey, Xueqing Maggie Lu, Yunlin Zhang, Kanupriya Whig, David C. Schultz, Sara Cherry, James Gerson, Stephen J Schuster, Patrizia Porazzi, Marco Ruella
Modulation of BCL-2 in Both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T-cell Immunotherapy against Cancer. Cancer discovery 12 (10) (2022)
Amanda Heard, Jack H Landmann, Ava R Hansen, Alkmini Papadopolou, Yu-Sung Hsu, Mehmet Emrah Selli, John M Warrington, John Lattin, Jufang Chang, Helen Ha, Martina Haug-Kroeper, Balraj Doray, Saar Gill, Marco Ruella, Katharina E Hayer, Matthew D Weitzman, Abby M Green, Regina Fluhrer, Nathan Singh
Antigen glycosylation regulates efficacy of CAR T cells targeting CD19. Nature communications 13 (1) (2022)
Sisi Zheng, Elisabeth Gillespie, Ammar S Naqvi, Katharina E Hayer, Zhiwei Ang, Manuel Torres-Diz, Mathieu Quesnel-Vallières, David A Hottman, Asen Bagashev, John Chukinas, Carolin Schmidt, Mukta Asnani, Rawan Shraim, Deanne M Taylor, Susan R Rheingold, Maureen M O'Brien, Nathan Singh, Kristen W Lynch, Marco Ruella, Yoseph Barash, Sarah K Tasian, Andrei Thomas-Tikhonenko
Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies. Blood cancer discovery 3 (2) (2022)
Concetta Quintarelli, Marika Guercio, Simona Manni, Iolanda Boffa, Matilde Sinibaldi, Stefano Di Cecca, Simona Caruso, Zeinab Abbaszadeh, Antonio Camera, Biancamaria Cembrola, Roselia Ciccone, Alberto Orfao, Lourdes Martin-Martin, Sara Gutierrez-Herrero, Maria Herrero-Garcia, Giovanni Cazzaniga, Vittorio Nunes, Simona Songia, Paolo Marcatili, Frederikke I Marin, Marco Ruella, Valentina Bertaina, Luciana Vinti, Francesca Del Bufalo, Mattia Algeri, Pietro Merli, Biagio De Angelis, Franco Locatelli
Strategy to prevent epitope masking in CAR.CD19+ B-cell leukemia blasts. Journal for immunotherapy of cancer 9 (6) (2022)
Melody Smith, Anqi Dai, Guido Ghilardi, Kimberly V Amelsberg, Sean M Devlin, Raymone Pajarillo, John B Slingerland, Silvia Beghi, Pamela S Herrera, Paul Giardina, Annelie Clurman, Emmanuel Dwomoh, Gabriel Armijo, Antonio L C Gomes, Eric R Littmann, Jonas Schluter, Emily Fontana, Ying Taur, Jae H Park, Maria Lia Palomba, Elizabeth Halton, Josel Ruiz, Tania Jain, Martina Pennisi, Aishat Olaide Afuye, Miguel-Ángel Perales, Craig W Freyer, Alfred Garfall, Shannon Gier, Sunita Nasta, Daniel Landsburg, James Gerson, Jakub Svoboda, Justin Cross, Elise A Chong, Sergio Giralt, Saar I Gill, Isabelle Riviere, David L Porter, Stephen J Schuster, Michel Sadelain, Noelle Frey, Renier J Brentjens, Carl H June, Eric G Pamer, Jonathan U Peled, Andrea Facciabene, Marcel R M van den Brink, Marco Ruella
Author Correction: Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy. Nature medicine (2022)
Melody Smith, Anqi Dai, Guido Ghilardi, Kimberly V Amelsberg, Sean M Devlin, Raymone Pajarillo, John B Slingerland, Silvia Beghi, Pamela S Herrera, Paul Giardina, Annelie Clurman, Emmanuel Dwomoh, Gabriel Armijo, Antonio L C Gomes, Eric R Littmann, Jonas Schluter, Emily Fontana, Ying Taur, Jae H Park, Maria Lia Palomba, Elizabeth Halton, Josel Ruiz, Tania Jain, Martina Pennisi, Aishat Olaide Afuye, Miguel-Ángel Perales, Craig W Freyer, Alfred Garfall, Shannon Gier, Sunita Nasta, Daniel Landsburg, James Gerson, Jakub Svoboda, Justin Cross, Elise A Chong, Sergio Giralt, Saar I Gill, Isabelle Riviere, David L Porter, Stephen J Schuster, Michel Sadelain, Noelle Frey, Renier J Brentjens, Carl H June, Eric G Pamer, Jonathan U Peled, Andrea Facciabene, Marcel R M van den Brink, Marco Ruella
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy. Nature medicine 28 (4) (2022)
Jean Lemoine, Marco Ruella, Roch Houot
Overcoming Intrinsic Resistance of Cancer Cells to CAR T-Cell Killing. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (23) (2021)
Nathan Singh, Noelle V Frey, Boris Engels, David M Barrett, Olga Shestova, Pranali Ravikumar, Katherine D Cummins, Yong Gu Lee, Raymone Pajarillo, Inkook Chun, Amy Shyu, Steven L Highfill, Andrew Price, Linlin Zhao, Liaomin Peng, Brian Granda, Melissa Ramones, Xueqing Maggie Lu, David A Christian, Jessica Perazzelli, Simon F Lacey, Nathan H Roy, Janis K Burkhardt, Florent Colomb, Mohammad Damra, Mohamed Abdel-Mohsen, Ting Liu, Dongfang Liu, Daron M Standley, Regina M Young, Jennifer L Brogdon, Stephan A Grupp, Carl H June, Shannon L Maude, Saar Gill, Marco Ruella
Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells. Nature medicine 27 (5) (2021)
Elise A Chong, Cécile Alanio, Jakub Svoboda, Sunita D Nasta, Daniel J Landsburg, Simon F Lacey, Marco Ruella, Siddharth Bhattacharyya, E John Wherry, Stephen J Schuster
Pembrolizumab for B-cell lymphomas relapsing after or refractory to CD19-directed CAR T-cell therapy. Blood (2021)
Guido Ghilardi, Peter Braendstrup, Elise A Chong, Stephen J Schuster, Jakub Svoboda, Marco Ruella
CAR-T TREK through the lymphoma universe, to boldly go where no other therapy has gone before. British journal of haematology 193 (3) (2020)
Michael Klichinsky, Marco Ruella, Olga Shestova, Xueqing Maggie Lu, Andrew Best, Martha Zeeman, Maggie Schmierer, Konrad Gabrusiewicz, Nicholas R Anderson, Nicholas E Petty, Katherine D Cummins, Feng Shen, Xinhe Shan, Kimberly Veliz, Kristin Blouch, Yumi Yashiro-Ohtani, Saad S Kenderian, Miriam Y Kim, Roddy S O'Connor, Stephen R Wallace, Miroslaw S Kozlowski, Dylan M Marchione, Maksim Shestov, Benjamin A Garcia, Carl H June, Saar I Gill
Human chimeric antigen receptor macrophages for cancer immunotherapy. Nature biotechnology 38 (8) (2020)
Nathan Singh, Yong Gu Lee, Olga Shestova, Pranali Ravikumar, Katharina E Hayer, Seok Jae Hong, Xueqing Maggie Lu, Raymone Pajarillo, Sangya Agarwal, Shunichiro Kuramitsu, Elena J Orlando, Karen Thudium Mueller, Charly R Good, Shelley L Berger, Ophir Shalem, Matthew D Weitzman, Noelle V Frey, Shannon L Maude, Stephan A Grupp, Carl H June, Saar Gill, Marco Ruella
Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction. Cancer discovery 10 (4) (2020)
Marco Ruella, Jun Xu, David M Barrett, Joseph A Fraietta, Tyler J Reich, David E Ambrose, Michael Klichinsky, Olga Shestova, Prachi R Patel, Irina Kulikovskaya, Farzana Nazimuddin, Vijay G Bhoj, Elena J Orlando, Terry J Fry, Hans Bitter, Shannon L Maude, Bruce L Levine, Christopher L Nobles, Frederic D Bushman, Regina M Young, John Scholler, Saar I Gill, Carl H June, Stephan A Grupp, Simon F Lacey, J Joseph Melenhorst
Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell. Nature medicine 24 (10) (2018)
Marco Ruella, Saad S Kenderian
Next-Generation Chimeric Antigen Receptor T-Cell Therapy: Going off the Shelf. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 31 (6) (2018)
Antonia Rotolo, Anastasios Karadimitris, Marco Ruella
Building upon the success of CART19: chimeric antigen receptor T cells for hematologic malignancies. Leukemia & lymphoma 59 (9) (2017)
Joseph A Fraietta, Kyle A Beckwith, Prachi R Patel, Marco Ruella, Zhaohui Zheng, David M Barrett, Simon F Lacey, Jan Joseph Melenhorst, Shannon E McGettigan, Danielle R Cook, Changfeng Zhang, Jun Xu, Priscilla Do, Jessica Hulitt, Sagar B Kudchodkar, Alexandria P Cogdill, Saar I Gill, David L Porter, Jennifer A Woyach, Meixiao Long, Amy J Johnson, Kami Maddocks, Natarajan Muthusamy, Bruce L Levine, Carl H June, John C Byrd, Marcela V Maus
Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia. Blood 127 (9) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Marco Ruella