Matthias Geyer

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 39

Top Venues

Science (New York, N.Y.)

Nature communications

The Journal of experimental medicine

bioRxiv : the preprint server for biology

University of Bonn

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Bonn Nov 01 2017

Germany

Director :: Institute of Structural Biology

Publications

Robert Düster, Kanchan Anand, Sophie Charlotte Binder, Maximilian Schmitz, Karl Gatterdam, Robert P Fisher, Matthias Geyer
Structural basis of Cdk7 activation by dual T-loop phosphorylation. Nature communications 15 (1) (2024)
Sana Hosni, Viola Kilian, Niklas Klümper, Daniela Gabbia, Katharina Sieckmann, Dillon Corvino, Anja Winkler, Miriam Saponaro, Karin Woersdoerfer, Doris Schmidt, Oliver Hahn, Ilaria Zanotto, Marina Bertlich, Marieta Ioana Toma, Tobias Bald, Markus Eckstein, Michael Hudecek, Matthias Geyer, Manuel Ritter, Dagmar Wachten, Sara De Martin, Abdullah Alajati
Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma. Cancer research 84 (5) (2024)
Robert Düster, Kanchan Anand, Sophie Charlotte Binder, Maximilian Schmitz, Karl Gatterdam, Robert P Fisher, Matthias Geyer
Structural basis of Cdk7 activation by dual T-loop phosphorylation. Nature communications 15 (1) (2024)
Robert Düster, Kanchan Anand, Sophie Charlotte Binder, Maximilian Schmitz, Karl Gatterdam, Robert P Fisher, Matthias Geyer
Structural basis of Cdk7 activation by dual T-loop phosphorylation. bioRxiv : the preprint server for biology (2024)
Robert Düster, Kanchan Anand, Sophie Charlotte Binder, Maximilian Schmitz, Karl Gatterdam, Robert P Fisher, Matthias Geyer
Structural basis of Cdk7 activation by dual T-loop phosphorylation. bioRxiv : the preprint server for biology (2024)
Robert Düster, Kanchan Anand, Sophie Charlotte Binder, Maximilian Schmitz, Karl Gatterdam, Robert P Fisher, Matthias Geyer
Structural basis of Cdk7 activation by dual T-loop phosphorylation. Nature communications 15 (1) (2024)
Robert Düster, Kanchan Anand, Sophie Charlotte Binder, Maximilian Schmitz, Karl Gatterdam, Robert P Fisher, Matthias Geyer
Structural basis of Cdk7 activation by dual T-loop phosphorylation. Nature communications 15 (1) (2024)
Camille Cosson, Romane Riou, Danish Patoli, Tingting Niu, Amaury Rey, Marine Groslambert, Charlotte De Rosny, Elodie Chatre, Omran Alatiff, Thomas Henry, Fabienne Venet, Florian Milhavet, Guilaine Boursier, Alexandre Belot, Yvan Jamilloux, Etienne Merlin, Agnès Duquesne, Gilles Grateau, Léa Savey, Alexandre Thibault Jacques Maria, Anne Pagnier, Solène Poutrel, Olivier Lambotte, Coralie Mallebranche, Samuel Ardois, Olivier Richer, Irène Lemelle, Frédéric Rieux-Laucat, Brigitte Bader-Meunier, Zahir Amoura, Isabelle Melki, Laurence Cuisset, Isabelle Touitou, Matthias Geyer, Stéphanie Ducharme-Bénard, Bénédicte F Py
Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation. The Journal of experimental medicine 221 (5) (2024)
Camille Cosson, Romane Riou, Danish Patoli, Tingting Niu, Amaury Rey, Marine Groslambert, Charlotte De Rosny, Elodie Chatre, Omran Alatiff, Thomas Henry, Fabienne Venet, Florian Milhavet, Guilaine Boursier, Alexandre Belot, Yvan Jamilloux, Etienne Merlin, Agnès Duquesne, Gilles Grateau, Léa Savey, Alexandre Thibault Jacques Maria, Anne Pagnier, Solène Poutrel, Olivier Lambotte, Coralie Mallebranche, Samuel Ardois, Olivier Richer, Irène Lemelle, Frédéric Rieux-Laucat, Brigitte Bader-Meunier, Zahir Amoura, Isabelle Melki, Laurence Cuisset, Isabelle Touitou, Matthias Geyer, Stéphanie Ducharme-Bénard, Bénédicte F Py
Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation. The Journal of experimental medicine 221 (5) (2024)
Camille Cosson, Romane Riou, Danish Patoli, Tingting Niu, Amaury Rey, Marine Groslambert, Charlotte De Rosny, Elodie Chatre, Omran Alatiff, Thomas Henry, Fabienne Venet, Florian Milhavet, Guilaine Boursier, Alexandre Belot, Yvan Jamilloux, Etienne Merlin, Agnès Duquesne, Gilles Grateau, Léa Savey, Alexandre Thibault Jacques Maria, Anne Pagnier, Solène Poutrel, Olivier Lambotte, Coralie Mallebranche, Samuel Ardois, Olivier Richer, Irène Lemelle, Frédéric Rieux-Laucat, Brigitte Bader-Meunier, Zahir Amoura, Isabelle Melki, Laurence Cuisset, Isabelle Touitou, Matthias Geyer, Stéphanie Ducharme-Bénard, Bénédicte F Py
Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation. The Journal of experimental medicine 221 (5) (2024)
Camille Cosson, Romane Riou, Danish Patoli, Tingting Niu, Amaury Rey, Marine Groslambert, Charlotte De Rosny, Elodie Chatre, Omran Alatiff, Thomas Henry, Fabienne Venet, Florian Milhavet, Guilaine Boursier, Alexandre Belot, Yvan Jamilloux, Etienne Merlin, Agnès Duquesne, Gilles Grateau, Léa Savey, Alexandre Thibault Jacques Maria, Anne Pagnier, Solène Poutrel, Olivier Lambotte, Coralie Mallebranche, Samuel Ardois, Olivier Richer, Irène Lemelle, Frédéric Rieux-Laucat, Brigitte Bader-Meunier, Zahir Amoura, Isabelle Melki, Laurence Cuisset, Isabelle Touitou, Matthias Geyer, Stéphanie Ducharme-Bénard, Bénédicte F Py
Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation. The Journal of experimental medicine 221 (5) (2024)
Robert Düster, Kanchan Anand, Sophie Charlotte Binder, Maximilian Schmitz, Karl Gatterdam, Robert P Fisher, Matthias Geyer
Structural basis of Cdk7 activation by dual T-loop phosphorylation. bioRxiv : the preprint server for biology (2024)
Sophie Charlotte Binder, Niels Schneberger, Maximilian Schmitz, Marianne Engeser, Matthias Geyer, Christophe Rouillon, Gregor Hagelueken
The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease. Nucleic acids research (2024)
Sana Hosni, Viola Kilian, Niklas Klümper, Daniela Gabbia, Katharina Sieckmann, Dillon Corvino, Anja Winkler, Miriam Saponaro, Karin Woersdoerfer, Doris Schmidt, Oliver Hahn, Ilaria Zanotto, Marina Bertlich, Marieta Ioana Toma, Tobias Bald, Markus Eckstein, Michael Hudecek, Matthias Geyer, Manuel Ritter, Dagmar Wachten, Sara De Martin, Abdullah Alajati
Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma. Cancer research 84 (5) (2024)
Sana Hosni, Viola Kilian, Niklas Klümper, Daniela Gabbia, Katharina Sieckmann, Dillon Corvino, Anja Winkler, Miriam Saponaro, Karin Woersdoerfer, Doris Schmidt, Oliver Hahn, Ilaria Zanotto, Marina Bertlich, Marieta Ioana Toma, Tobias Bald, Markus Eckstein, Michael Hudecek, Matthias Geyer, Manuel Ritter, Dagmar Wachten, Sara De Martin, Abdullah Alajati
Adipocyte precursor-derived NRG1 promotes resistance to FGFR inhibition in urothelial carcinoma. Cancer research (2024)
Anja Kopp, Gregor Hagelueken, Isabell Jamitzky, Jonas Moecking, Lisa D J Schiffelers, Florian Ingo Schmidt, Matthias Geyer
Pyroptosis inhibiting nanobodies block Gasdermin D pore formation. Nature communications 14 (1) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Rebecca Brinkschulte, David M Fußhöller, Florian Hoss, Juan F Rodríguez-Alcázar, Mario A Lauterbach, Carl-Christian Kolbe, Melanie Rauen, Semra Ince, Christian Herrmann, Eicke Latz, Matthias Geyer
ATP-binding and hydrolysis of human NLRP3. Communications biology 5 (1) (2022)
Inga V Hochheiser, Heide Behrmann, Gregor Hagelueken, Juan F Rodríguez-Alcázar, Anja Kopp, Eicke Latz, Elmar Behrmann, Matthias Geyer
Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation. Science advances 8 (19) (2022)
Christophe Rouillon, Niels Schneberger, Haotian Chi, Katja Blumenstock, Stefano Da Vela, Katrin Ackermann, Jonas Moecking, Martin F Peter, Wolfgang Boenigk, Reinhard Seifert, Bela Ernest Bode, Jonathan L Schmid-Burgk, Dmitri I Svergun, Matthias Geyer, Malcolm F White, Gregor Hagelueken
Antiviral signaling by a cyclic nucleotide activated CRISPR protease. Nature (2022)
Robert Düster, Yanlong Ji, Kuan-Ting Pan, Henning Urlaub, Matthias Geyer
Functional characterization of the human Cdk10/Cyclin Q complex. Open biology 12 (3) (2022)
Roua Hassoun, Constanze Erdmann, Sebastian Schmitt, Setsuko Fujita-Becker, Andreas Mügge, Rasmus R Schröder, Matthias Geyer, Mina Borbor, Kornelia Jaquet, Nazha Hamdani, Hans Georg Mannherz
Functional Characterization of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G). International journal of molecular sciences 23 (8) (2022)
Lea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, Anja Vom Hemdt, Jennifer Deborah Wuerth, Lisa D J Schiffelers, Yonas M Tesfamariam, Florian N Gohr, Laura Klein, Ines H Kaltheuner, Stefan Ebner, Dorothee Johanna Lapp, Jacob Mayer, Jonas Moecking, Hidde L Ploegh, Eicke Latz, Rüdiger Klein, Matthias Geyer, Beate Mareike Kümmerer, Florian Ingo Schmidt
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection. The Journal of experimental medicine 220 (1) (2022)
Martin F Peter, Jan Andreas Ruland, Peer Depping, Niels Schneberger, Emmanuele Severi, Jonas Moecking, Karl Gatterdam, Sarah Tindall, Alexandre Durand, Veronika Heinz, Jan Peter Siebrasse, Paul-Albert Koenig, Matthias Geyer, Christine Ziegler, Ulrich Kubitscheck, Gavin Hugh Thomas, Gregor Hagelueken
Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter. Nature communications 13 (1) (2022)
Annemarie Steiner, Katja Hrovat-Schaale, Ignazia Prigione, Chien-Hsiung Yu, Pawat Laohamonthonkul, Cassandra R Harapas, Ronnie Ren Jie Low, Dominic De Nardo, Laura F Dagley, Michael J Mlodzianoski, Kelly L Rogers, Thomas Zillinger, Gunther Hartmann, Michael P Gantier, Marco Gattorno, Matthias Geyer, Stefano Volpi, Sophia Davidson, Seth L Masters
Deficiency in coatomer complex I causes aberrant activation of STING signalling. Nature communications 13 (1) (2022)
Kai Funke, Robert Düster, Prince De-Graft Wilson, Lena Arévalo, Matthias Geyer, Hubert Schorle
Transcriptional CDK Inhibitors as Potential Treatment Option for Testicular Germ Cell Tumors. Cancers 14 (7) (2022)
Inga V Hochheiser, Michael Pilsl, Gregor Hagelueken, Jonas Moecking, Michael Marleaux, Rebecca Brinkschulte, Eicke Latz, Christoph Engel, Matthias Geyer
Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3. Nature 604 (7904) (2022)
Constanze Erdmann, Roua Hassoun, Sebastian Schmitt, Carlos Kikuti, Anne Houdusse, Antonina Joanna Mazur, Andreas Mügge, Nazha Hamdani, Matthias Geyer, Kornelia Jaquet, Hans Georg Mannherz
Integration of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G) into Cellular Structures. Antioxidants (Basel, Switzerland) 10 (7) (2021)
Paul-Albert Koenig, Hrishikesh Das, Hejun Liu, Beate M Kümmerer, Florian N Gohr, Lea-Marie Jenster, Lisa D J Schiffelers, Yonas M Tesfamariam, Miki Uchima, Jennifer Deborah Wuerth, Karl Gatterdam, Natalia Ruetalo, Maria H Christensen, Caroline I Fandrey, Sabine Normann, Jan M P Tödtmann, Steffen Pritzl, Leo Hanke, Jannik Boos, Meng Yuan, Xueyong Zhu, Jonathan L Schmid-Burgk, Hiroki Kato, Michael Schindler, Ian A Wilson, Matthias Geyer, Kerstin U Ludwig, B Martin Hällberg, Nicholas C Wu, Florian Ingo Schmidt
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science (New York, N.Y.) 371 (6530) (2021)
Ines H Kaltheuner, Kanchan Anand, Jonas Moecking, Robert Düster, Jinhua Wang, Nathanael S Gray, Matthias Geyer
Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation. Nature communications 12 (1) (2021)
Zheng Fan, Jennifer R Devlin, Simon J Hogg, Maria A Doyle, Paul F Harrison, Izabela Todorovski, Leonie A Cluse, Deborah A Knight, Jarrod J Sandow, Gareth Peter Gregory, Andrew Fox, Traude H Beilharz, Nicholas Kwiatkowski, Nichollas E Scott, Ana Tufegdzic Vidakovic, Gavin P Kelly, Jesper Q Svejstrup, Matthias Geyer, Nathanael S Gray, Stephin J Vervoort, Ricky W Johnstone
CDK13 cooperates with CDK12 to control global RNA polymerase II processivity. Science advances 6 (18) (2020)
Michael Marleaux, Kanchan Anand, Eicke Latz, Matthias Geyer
Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly. FEBS letters 594 (15) (2020)

Matthias Geyer.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Matthias Geyer