Alan Saghatelian

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 41

Top Venues

Nature communications

Biochemistry

bioRxiv : the preprint server for biology

Molecular psychiatry

Salk Institute for Biological Studies

Scripps Research Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Salk Institute for Biological Studies

United States

Professor :: PBL

Harvard University

United States

Associate Professor :: Chemsitry and Chemical Biology

Harvard University

United States

Assistant Professor :: Chemistry and Chemical Biology

Education History

Scripps Research Institute

United States

PHD :: Chemistry

UCLA Division of Physical Sciences

United States

BSC :: Chemistry

Publications

Soumaya Zlitni, Sierra Bowden, Hila Sberro, Marcelo Der Torossian Torres, Joan M Vaughan, Antonio F M Pinto, Yishay Pinto, Daniel Fernandez, Hannes Röst, Alan Saghatelian, de la Fuente-Nunez Cesar, Ami Siddharth Bhatt
Dual quorum-sensing control of purine biosynthesis drives pathogenic fitness of Enterococcus faecalis . bioRxiv : the preprint server for biology (2024)
Shuai Yan, Anna Santoro, Micah J Niphakis, Antonio F M Pinto, Christopher L Jacobs, Rasheed Ahmad, Radu M Suciu, Bryan R Fonslow, Rachel A Herbst-Graham, Nhi Ngo, Cassandra L Henry, Dylan M Herbst, Alan Saghatelian, Barbara B Kahn, Evan D Rosen
Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels. Nature communications 15 (1) (2024)
Eduardo Vieira de Souza, Angie L Bookout, Christopher A Barnes, Brendan Miller, Pablo Machado, Luiz A Basso, Cristiano Valim Bizarro, Alan Saghatelian
Rp3: Ribosome profiling-assisted proteogenomics improves coverage and confidence during microprotein discovery. Nature communications 15 (1) (2024)
Amandine Chaix, Terry Lin, Bastian Ramms, Roy G Cutler, Tiffani Le, Catherine Lopez, Phuong Miu, Antonio F M Pinto, Alan Saghatelian, Martin P Playford, Nehal N Mehta, Mark P Mattson, Philip L S M Gordts, Joseph L Witztum, Satchidananda Panda
Time-Restricted Feeding Reduces Atherosclerosis in LDLR KO Mice but Not in ApoE Knockout Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (9) (2024)
Eduardo Vieira de Souza, Angie L Bookout, Christopher A Barnes, Brendan Miller, Pablo Machado, Luiz A Basso, Cristiano Valim Bizarro, Alan Saghatelian
Rp3: Ribosome profiling-assisted proteogenomics improves coverage and confidence during microprotein discovery. Nature communications 15 (1) (2024)
Amandine Chaix, Terry Lin, Bastian Ramms, Roy G Cutler, Tiffani Le, Catherine Lopez, Phuong Miu, Antonio F M Pinto, Alan Saghatelian, Martin P Playford, Nehal N Mehta, Mark P Mattson, Philip L S M Gordts, Joseph L Witztum, Satchidananda Panda
Time-Restricted Feeding Reduces Atherosclerosis in LDLR KO Mice but Not in ApoE Knockout Mice. Arteriosclerosis, thrombosis, and vascular biology (2024)
Amandine Chaix, Terry Lin, Bastian Ramms, Roy G Cutler, Tiffani Le, Catherine Lopez, Phuong Miu, Antonio F M Pinto, Alan Saghatelian, Martin P Playford, Nehal N Mehta, Mark P Mattson, Philip L S M Gordts, Joseph L Witztum, Satchidananda Panda
Time-Restricted Feeding Reduces Atherosclerosis in LDLR KO Mice but Not in ApoE Knockout Mice. Arteriosclerosis, thrombosis, and vascular biology 44 (9) (2024)
Soumaya Zlitni, Sierra Bowden, Hila Sberro, Marcelo Der Torossian Torres, Joan M Vaughan, Antonio F M Pinto, Yishay Pinto, Daniel Fernandez, Hannes Röst, Alan Saghatelian, de la Fuente-Nunez Cesar, Ami Siddharth Bhatt
Dual quorum-sensing control of purine biosynthesis drives pathogenic fitness of Enterococcus faecalis . bioRxiv : the preprint server for biology (2024)
Eduardo Vieira de Souza, Angie L Bookout, Christopher A Barnes, Brendan Miller, Pablo Machado, Luiz A Basso, Cristiano Valim Bizarro, Alan Saghatelian
Rp3: Ribosome profiling-assisted proteogenomics improves coverage and confidence during microprotein discovery. Nature communications 15 (1) (2024)
Eduardo Vieira de Souza, Angie L Bookout, Christopher A Barnes, Brendan Miller, Pablo Machado, Luiz A Basso, Cristiano Valim Bizarro, Alan Saghatelian
Rp3: Ribosome profiling-assisted proteogenomics improves coverage and confidence during microprotein discovery. Nature communications 15 (1) (2024)
Shuai Yan, Anna Santoro, Micah J Niphakis, Antonio F M Pinto, Christopher L Jacobs, Rasheed Ahmad, Radu M Suciu, Bryan R Fonslow, Rachel A Herbst-Graham, Nhi Ngo, Cassandra L Henry, Dylan M Herbst, Alan Saghatelian, Barbara B Kahn, Evan D Rosen
Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels. Nature communications 15 (1) (2024)
Shuai Yan, Anna Santoro, Micah J Niphakis, Antonio F M Pinto, Christopher L Jacobs, Rasheed Ahmad, Radu M Suciu, Bryan R Fonslow, Rachel A Herbst-Graham, Nhi Ngo, Cassandra L Henry, Dylan M Herbst, Alan Saghatelian, Barbara B Kahn, Evan D Rosen
Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels. Nature communications 15 (1) (2024)
Eduardo Vieira de Souza, Angie L Bookout, Christopher A Barnes, Brendan Miller, Pablo Machado, Luiz A Basso, Cristiano Valim Bizarro, Alan Saghatelian
The Integration of Proteogenomics and Ribosome Profiling Circumvents Key Limitations to Increase the Coverage and Confidence of Novel Microproteins. bioRxiv : the preprint server for biology (2023)
Lucia Morgado-Palacin, Jessie A Brown, Cholsoon Jang, Juana María García-Pedrero, Farhad Forouhar, S Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodríguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F Fernandez, Mario Fernández Fraga, Arianna L Kim, Jorge Santos-Juanes, David M Owens, Juan P Rodrigo, Alan Saghatelian, Adolfo A Ferrando
The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma. Nature communications 14 (1) (2023)
Lucia Morgado-Palacin, Jessie A Brown, Cholsoon Jang, Juana María García-Pedrero, Farhad Forouhar, S Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodríguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F Fernandez, Mario Fernández Fraga, Arianna L Kim, Jorge Santos-Juanes, David M Owens, Juan P Rodrigo, Alan Saghatelian, Adolfo A Ferrando
The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma. Nature communications 14 (1) (2023)
Lucia Morgado-Palacin, Jessie A Brown, Cholsoon Jang, Juana María García-Pedrero, Farhad Forouhar, S Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodríguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F Fernandez, Mario Fernández Fraga, Arianna L Kim, Jorge Santos-Juanes, David M Owens, Juan P Rodrigo, Alan Saghatelian, Adolfo A Ferrando
The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma. Nature communications 14 (1) (2023)
Brendan Miller, Su-Jeong Kim, Hemal H Mehta, Kevin Cao, Hiroshi Kumagai, Neehar Thumaty, Naphada Leelaprachakul, Regina Gonzalez Braniff, Henry Jiao, Joan Vaughan, Jolene Diedrich, Alan Saghatelian, Thalida Em Arpawong, Eileen M Crimmins, Nilüfer Ertekin-Taner, Meral A Tubi, Evan T Hare, Meredith N Braskie, Léa Décarie-Spain, Scott E Kanoski, Francine Grodstein, David A Bennett, Lu Zhao, Arthur W Toga, Junxiang Wan, Kelvin Yen, Pinchas Cohen, null null
Correction: Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE. Molecular psychiatry (2023)
Lina Xie, Marianne E Bowman, Gordon V Louie, Cheng Zhang, Maziar S Ardejani, Xuemei Huang, Qian Chu, Cynthia J Donaldson, Joan M Vaughan, Huanqi Shan, Evan T Powers, Jeffrey W Kelly, Dimitry Lyumkis, Joseph A P Noel, Alan Saghatelian
Biochemistry and Protein Interactions of the CYREN Microprotein. Biochemistry (2023)
Lucia Morgado-Palacin, Jessie A Brown, Cholsoon Jang, Juana María García-Pedrero, Farhad Forouhar, S Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodríguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F Fernandez, Mario Fernández Fraga, Arianna L Kim, Jorge Santos-Juanes, David M Owens, Juan P Rodrigo, Alan Saghatelian, Adolfo A Ferrando
The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma. Nature communications 14 (1) (2023)
Martin Riecan, Veronika Domanska, Cristina Lupu, Maulin Patel, Michaela Vondrackova, Martin Rossmeisl, Alan Saghatelian, Florea Lupu, Ondřej Kuda
Tissue-specific sex difference in the metabolism of fatty acid esters of hydroxy fatty acids. bioRxiv : the preprint server for biology (2023)
Brendan Miller, Su-Jeong Kim, Hemal H Mehta, Kevin Cao, Hiroshi Kumagai, Neehar Thumaty, Naphada Leelaprachakul, Regina Gonzalez Braniff, Henry Jiao, Joan Vaughan, Jolene Diedrich, Alan Saghatelian, Thalida Em Arpawong, Eileen M Crimmins, Nilüfer Ertekin-Taner, Meral A Tubi, Evan T Hare, Meredith N Braskie, Léa Décarie-Spain, Scott E Kanoski, Francine Grodstein, David A Bennett, Lu Zhao, Arthur W Toga, Junxiang Wan, Kelvin Yen, Pinchas Cohen, null null
Correction: Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE. Molecular psychiatry (2023)
Dan Tan, Srihari Konduri, Meric Erikci Ertunc, Pan Zhang, Justin Wang, Tina Chang, Antonio F M Pinto, Andrea Rocha, Cynthia J Donaldson, Joan M Vaughan, Raissa G Ludwig, Elizabeth Willey, Manasi Iyer, Peter C Gray, Pamela Maher, Nicola J Allen, J Bradley Zuchero, Andrew Dillin, Marcelo Alves da Silva Mori, Steven G Kohama, Dionicio Siegel, Alan Saghatelian
A class of anti-inflammatory lipids decrease with aging in the central nervous system. Nature chemical biology (2022)
Jonathan M Mudge, Jorge Ruiz-Orera, John R Prensner, Marie A Brunet, Ferriol Calvet, Irwin Jungreis, Jose Manuel Gonzalez, Michele Magrane, Cholsoon Jang, Jana Felicitas Schulz, Yucheng T Yang, M Mar Albà, Julie L Aspden, Pavel V Baranov, Ariel Alejandro Bazzini, Elspeth A Bruford, Maria Jesus Martin, Lorenzo Calviello, Anne-Ruxandra Carvunis, Jin Chen, Juan Pablo Couso, Eric W Deutsch, Paul Flicek, Adam Frankish, Mark Gerstein, Norbert Hübner, Nicholas T Ingolia, Manolis Kellis, Gerben Menschaert, Robert L Moritz, Uwe Ohler, Xavier Roucou, Alan Saghatelian, Jonathan S Weissman, Sebastiaan van Heesch
Standardized annotation of translated open reading frames. Nature biotechnology 40 (7) (2022)
Eduardo Vieira de Souza, Pedro Ferrari Dalberto, Vinicius Pellisoli Machado, Adriana Canedo, Alan Saghatelian, Pablo Machado, Luiz Augusto Basso, Cristiano Valim Bizarro
µProteInS-a proteogenomics pipeline for finding novel bacterial microproteins encoded by small ORFs. Bioinformatics (Oxford, England) 38 (9) (2022)
Brendan Miller, Su-Jeong Kim, Hemal H Mehta, Kevin Cao, Hiroshi Kumagai, Neehar Thumaty, Naphada Leelaprachakul, Henry Jiao, Joan Vaughan, Jolene Diedrich, Alan Saghatelian, Thalida Em Arpawong, Eileen M Crimmins, Nilüfer Ertekin-Taner, Meral A Tubi, Evan T Hare, Meredith N Braskie, Léa Décarie-Spain, Scott E Kanoski, Francine Grodstein, David A Bennett, Lu Zhao, Arthur W Toga, Junxiang Wan, Kelvin Yen, Pinchas Cohen
Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE. Molecular psychiatry (2022)
Rucha Patel, Anna Santoro, Peter Hofer, Dan Tan, Monika Oberer, Andrew T Nelson, Srihari Konduri, Dionicio Siegel, Rudolf Zechner, Alan Saghatelian, Barbara B Kahn
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids. Nature 606 (7916) (2022)
Christopher Lane Sander, Avery E Sears, Antonio F M Pinto, Elliot H Choi, Shirin Kahremany, Fangyuan Gao, David Salom, Hui Jin, Els Pardon, Susie Suh, Zhiqian Dong, Jan Steyaert, Alan Saghatelian, Dorota Skowronska-Krawczyk, Philip D Kiser, Krzysztof Palczewski
Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition. The Journal of cell biology 220 (8) (2021)
Minseob Koh, Insha Ahmad, Yeonjin Ko, Yuxiang Zhang, Cholsoon Jang, Jolene K Diedrich, Qian Chu, James J Moresco, Michael A Erb, Alan Saghatelian, Peter G Schultz, Michael J Bollong
A short ORF-encoded transcriptional regulator. Proceedings of the National Academy of Sciences of the United States of America 118 (4) (2021)
Thangaselvam Muthusamy, Thekla Cordes, Michal K Handzlik, Le You, Esther W Lim, Jivani Gengatharan, Antonio F M Pinto, Mehmet G Badur, Matthew J Kolar, Martina Wallace, Alan Saghatelian, Christian M Metallo
Serine restriction alters sphingolipid diversity to constrain tumour growth. Nature 586 (7831) (2020)
Poshen B Chen, Audrey S Black, Adam L Sobel, Yannan Zhao, Purba Mukherjee, Bhuvan Molparia, Nina E Moore, German R Aleman Muench, Jiejun Wu, Weixuan Chen, Antonio F M Pinto, Bruce E Maryanoff, Alan Saghatelian, Pejman Soroosh, Ali Torkamani, Luke J Leman, M Reza Ghadiri
Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis. Nature biotechnology 38 (11) (2020)
Thomas F Martinez, Joan Vaughan, Alan Saghatelian
Insights into GLP-1 Receptor Activation with a Nonpeptide Agonist. Biochemistry 59 (16) (2020)
Qian Chu, Alan Saghatelian
A Hidden ORF Reveals an Immune Protector. Biochemistry 58 (8) (2019)
Dan Tan, Meric Erikci Ertunc, Srihari Konduri, Justin Zhang, Antonio M Pinto, Qian Chu, Barbara B Kahn, Dionicio Siegel, Alan Saghatelian
Discovery of FAHFA-Containing Triacylglycerols and Their Metabolic Regulation. Journal of the American Chemical Society 141 (22) (2019)
Huijing Wang, Matthew J Kolar, Tina Chang, José Rizo, Srihari Konduri, Clare McNerlin, Alan Saghatelian, Dionicio Siegel
Stereochemistry of Linoleic Acid Esters of Hydroxy Linoleic Acids. Organic letters 21 (19) (2019)
Qian Chu, Cholsoon Jang, Sammy Weiser Novak, Cynthia J Donaldson, Dan Tan, Joan M Vaughan, Tina Chang, Jolene K Diedrich, Leonardo R Andrade, Andrew Kim, Tong Zhang, Uri Manor, Alan Saghatelian
Regulation of the ER stress response by a mitochondrial microprotein. Nature communications 10 (1) (2019)
Matthew J Kolar, Srihari Konduri, Tina Chang, Huijing Wang, Clare McNerlin, Lena Ohlsson, Magnus Härröd, Dionicio Siegel, Alan Saghatelian
Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals. The Journal of biological chemistry 294 (27) (2019)
Cholsoon Jang, Qian Chu, Cynthia Donaldson, Dan Tan, Maxim N Shokhirev, Alan Saghatelian
Accurate annotation of human protein-coding small open reading frames. Nature chemical biology 16 (4) (2019)
Annie Rathore, Qian Chu, Dan Tan, Thomas F Martinez, Cynthia J Donaldson, Jolene K Diedrich, John Yates Iii, Alan Saghatelian
MIEF1 Microprotein Regulates Mitochondrial Translation. Biochemistry 57 (38) (2018)
Matthew J Kolar, Andrew T Nelson, Tina Chang, Meric Erikci Ertunc, Mitchell P Christy, Lena Ohlsson, Magnus Härröd, Barbara B Kahn, Dionicio Siegel, Alan Saghatelian
Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements. Analytical chemistry 90 (8) (2018)
Qian Chu, Annie Rathore, Jolene K Diedrich, Cynthia J Donaldson, John Yates Iii, Alan Saghatelian
Identification of Microprotein-Protein Interactions via APEX Tagging. Biochemistry 56 (26) (2017)
Alan Saghatelian
Novel Biology and Druggable Targets via Chemoproteomics. Biochemistry 56 (50) (2017)

Alan Saghatelian.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Alan Saghatelian