Charles Hatton (Charlie Hatton)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2020-2023
Publications (10 Years): 9

Top Topics

Gene Expression

Acute Myeloid Leukemia

Allogeneic Hematopoietic Stem Cell Transplantation

Top Venues

Cancer discovery

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Leslie Duplaquet, Yixiang Li, Matthew A Booker, Yingtian Xie, Sarah Naomi Olsen, Radhika A Patel, Deli Hong, Charles Hatton, Thomas Denize, Emily Walton, Yasmin N Laimon, Rong Li, Yijia Jiang, Roderick T Bronson, Jackson Southard, Shuqiang Li, Sabina Signoretti, Xintao Qiu, Paloma Cejas, Scott A Armstrong, Henry W Long, Michael Y Tolstorukov, Michael C Haffner, Matthew G Oser
KDM6A epigenetically regulates subtype plasticity in small cell lung cancer. Nature cell biology (2023)
Wallace Bourgeois, Jevon A Cutler, Brandon J Aubrey, Daniela V Wenge, Florian Perner, Cynthia Martucci, Jill A Henrich, Kelly S Klega, Radosław P Nowak, Katherine Aleisha Donovan, Meaghan Boileau, Yanhe Wen, Charles Hatton, Athina A Apazidis, Sarah Naomi Olsen, Nadia Kirmani, Yana Pikman, Jessica A Pollard, Jennifer A Perry, Adam S Sperling, Benjamin L Ebert, Gerard M McGeehan, Brian D Crompton, Eric S Fischer, Scott A Armstrong
Mezigdomide is effective alone and in combination with Menin inhibition in pre-clinical models of KMT2A-r and NPM1c AML. Blood (2023)
Jonathan D Paolino, Boris Dimitrov, Beth Apsel Winger, Angélica Sandoval-Pérez, Amith Vikram Rangarajan, Nicole Ocasio-Martinez, Harrison K Tsai, Yuting Li, Amanda L Robichaud, Delan Khalid, Charles Hatton, Riaz Gillani, Petri Polonen, Anthony Dilig, Giacomo Gotti, Julia Kavanagh, Asmani A Adhav, Sean Gow, Jonathan M Tsai, Yen-Der Li, Benjamin L Ebert, Eliezer Van Allen, Jacob R Bledsoe, Annette S Kim, Sarah K Tasian, Stacy L Cooper, Todd M Cooper, Nobuko Hijiya, Maria-Luisa Sulis, Neerav N Shukla, Jeffrey A Magee, Charles G Mullighan, Michael J Burke, Marlise R Luskin, Brenton G Mar, Matthew P Jacobson, Marian H Harris, Kimberly Stegmaier, Andrew E Place, Yana Pikman
Integration of genomic sequencing drives therapeutic targeting of PDGFRA in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Brandon J Aubrey, Jevon A Cutler, Wallace Bourgeois, Katherine A Donovan, Shengqing Gu, Charles Hatton, Sarah Perlee, Florian Perner, Homa Rahnamoun, Alexandra C P Theall, Jill A Henrich, Qian Zhu, Radosław P Nowak, Young Joon Kim, Salma Parvin, Anjali Cremer, Sarah Naomi Olsen, Nicholas A Eleuteri, Yana Pikman, Gerard M McGeehan, Kimberly Stegmaier, Anthony G Letai, Eric S Fischer, X Shirley Liu, Scott A Armstrong
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. Nature cancer 3 (5) (2022)
Hannah J Uckelmann, Elena L Haarer, Reina Takeda, Eric M Wong, Charles Hatton, Christian Marinaccio, Florian Perner, Masooma Rajput, Noa J C Antonissen, Yanhe Wen, Lu Yang, Lorenzo Brunetti, Chun-Wei David Chen, Scott A Armstrong
Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia. Cancer discovery (2022)
Matthew L Hemming, Morgan R Benson, Michael A Loycano, Justin A Anderson, Jessica L Andersen, Madeleine L Taddei, Andrei V Krivtsov, Brandon J Aubrey, Jevon A Cutler, Charles Hatton, Ewa Sicinska, Scott A Armstrong
MOZ and Menin-MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor. Cancer discovery 12 (7) (2022)
Emily B Heikamp, Jill A Henrich, Florian Perner, Eric M Wong, Charles Hatton, Yanhe Wen, Sonali P Barwe, Anilkumar Gopalakrishnapillai, Haiming Xu, Hannah Julia Uckelmann, Sumiko Takao, Yaniv Kazansky, Yana Pikman, Gerard M McGeehan, Edward A Kolb, Alex Kentsis, Scott A Armstrong
The Menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML. Blood (2021)
Florian Perner, Tina M Schnoeder, Yijun Xiong, Ashok Kumar Jayavelu, Nomusa Mashamba, Nuria Tubio Santamaria, Nicolas Huber, Kristina Todorova, Charles Hatton, Birgit Perner, Theresa Eifert, Ciara Murphy, Maximilian Hartmann, Jessica I Hoell, Nicolas Schröder, Sabine Brandt, Andreas Hochhaus, Peter R Mertens, Matthias Mann, Scott A Armstrong, Anna Mandinova, Florian H Heidel
YBX1 mediates translation of oncogenic transcripts to control cell competition in AML. Leukemia (2021)
Hannah J Uckelmann, Stephanie M Kim, Eric M Wong, Charles Hatton, Hugh Giovinazzo, Jayant Y Gadrey, Andrei V Krivtsov, Frank G Rücker, Konstanze Döhner, Gerard M McGeehan, Ross L Levine, Lars Bullinger, George S Vassiliou, Scott A Armstrong
Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia. Science (New York, N.Y.) 367 (6477) (2020)