Christoph Kuppe (C Kuppe)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 44

Top Topics

Hodgkin Lymphoma

Polycystic Kidney Disease

Top Venues

Nature communications

Molecular systems biology

Genome medicine

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Niklas Klümper, Ngoc Khanh Tran, Stefanie Zschäbitz, Oliver Hahn, Thomas Büttner, Florian Roghmann, Christian Bolenz, Friedemann Zengerling, Constantin Schwab, Dora Nagy, Marieta Ioana Toma, Glen Kristiansen, Hendrik Heers, Philipp Ivanyi, Guenter Niegisch, Camilla Marisa Grunewald, Christopher Darr, Arian Farid, Katrin Schlack, Mahmoud Abbas, Can Aydogdu, Jozefina Casuscelli, Theresa Mokry, Michael Mayr, Dora Niedersüß-Beke, Steffen Rausch, Dimo Dietrich, Jonas Saal, Joerg Ellinger, Manuel Ritter, Abdullah Alajati, Christoph Kuppe, Joshua J Meeks, Francisco Emilio Vera-Badillo, José Alberto Nakauma-González, Joost Boormans, Kerstin Junker, Arndt Hartmann, Viktor Gruenwald, Michael Hudecek, Markus Eckstein
NECTIN4 Amplification Is Frequent in Solid Tumors and Predicts Enfortumab Vedotin Response in Metastatic Urothelial Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Paul Kiessling, Christoph Kuppe
Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases. Genome medicine 16 (1) (2024)
Paul Kiessling, Christoph Kuppe
Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases. Genome medicine 16 (1) (2024)
Feng Ren, Alex Aliper, Jian Chen, Heng Zhao, Sujata Rao, Christoph Kuppe, Ivan V Ozerov, Man Zhang, Klaus Witte, Chris Kruse, Vladimir Aladinskiy, Yan Ivanenkov, Daniil Polykovskiy, Yanyun Fu, Eugene Babin, Junwen Qiao, Xing Liang, Zhenzhen Mou, Hui Wang, Frank W Pun, Pedro Torres Ayuso, Alexander Veviorskiy, Dandan Song, Sang Liu, Bei Zhang, Vladimir Naumov, Xiaoqiang Ding, Andrey Kukharenko, Evgeny Izumchenko, Alex Zhavoronkov
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models. Nature biotechnology (2024)
Niklas Klümper, Ngoc Khanh Tran, Stefanie Zschäbitz, Oliver Hahn, Thomas Büttner, Florian Roghmann, Christian Bolenz, Friedemann Zengerling, Constantin Schwab, Dora Nagy, Marieta Ioana Toma, Glen Kristiansen, Hendrik Heers, Philipp Ivanyi, Guenter Niegisch, Camilla Marisa Grunewald, Christopher Darr, Arian Farid, Katrin Schlack, Mahmoud Abbas, Can Aydogdu, Jozefina Casuscelli, Theresa Mokry, Michael Mayr, Dora Niedersüß-Beke, Steffen Rausch, Dimo Dietrich, Jonas Saal, Joerg Ellinger, Manuel Ritter, Abdullah Alajati, Christoph Kuppe, Joshua J Meeks, Francisco Emilio Vera-Badillo, José Alberto Nakauma-González, Joost Boormans, Kerstin Junker, Arndt Hartmann, Viktor Gruenwald, Michael Hudecek, Markus Eckstein
NECTIN4 Amplification Is Frequent in Solid Tumors and Predicts Enfortumab Vedotin Response in Metastatic Urothelial Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (20) (2024)
Feng Ren, Alex Aliper, Jian Chen, Heng Zhao, Sujata Rao, Christoph Kuppe, Ivan V Ozerov, Man Zhang, Klaus Witte, Chris Kruse, Vladimir Aladinskiy, Yan Ivanenkov, Daniil Polykovskiy, Yanyun Fu, Eugene Babin, Junwen Qiao, Xing Liang, Zhenzhen Mou, Hui Wang, Frank W Pun, Pedro Torres Ayuso, Alexander Veviorskiy, Dandan Song, Sang Liu, Bei Zhang, Vladimir Naumov, Xiaoqiang Ding, Andrey Kukharenko, Evgeny Izumchenko, Alex Zhavoronkov
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models. Nature biotechnology (2024)
Niklas Klümper, Ngoc Khanh Tran, Stefanie Zschäbitz, Oliver Hahn, Thomas Büttner, Florian Roghmann, Christian Bolenz, Friedemann Zengerling, Constantin Schwab, Dora Nagy, Marieta Ioana Toma, Glen Kristiansen, Hendrik Heers, Philipp Ivanyi, Guenter Niegisch, Camilla Marisa Grunewald, Christopher Darr, Arian Farid, Katrin Schlack, Mahmoud Abbas, Can Aydogdu, Jozefina Casuscelli, Theresa Mokry, Michael Mayr, Dora Niedersüß-Beke, Steffen Rausch, Dimo Dietrich, Jonas Saal, Joerg Ellinger, Manuel Ritter, Abdullah Alajati, Christoph Kuppe, Joshua J Meeks, Francisco Emilio Vera-Badillo, José Alberto Nakauma-González, Joost Boormans, Kerstin Junker, Arndt Hartmann, Viktor Gruenwald, Michael Hudecek, Markus Eckstein
NECTIN4 Amplification Is Frequent in Solid Tumors and Predicts Enfortumab Vedotin Response in Metastatic Urothelial Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (20) (2024)
Paul Kiessling, Christoph Kuppe
Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases. Genome medicine 16 (1) (2024)
Niklas Klümper, Ngoc Khanh Tran, Stefanie Zschäbitz, Oliver Hahn, Thomas Büttner, Florian Roghmann, Christian Bolenz, Friedemann Zengerling, Constantin Schwab, Dora Nagy, Marieta Ioana Toma, Glen Kristiansen, Hendrik Heers, Philipp Ivanyi, Guenter Niegisch, Camilla Marisa Grunewald, Christopher Darr, Arian Farid, Katrin Schlack, Mahmoud Abbas, Can Aydogdu, Jozefina Casuscelli, Theresa Mokry, Michael Mayr, Dora Niedersüß-Beke, Steffen Rausch, Dimo Dietrich, Jonas Saal, Joerg Ellinger, Manuel Ritter, Abdullah Alajati, Christoph Kuppe, Joshua J Meeks, Francisco Emilio Vera-Badillo, José Alberto Nakauma-González, Joost Boormans, Kerstin Junker, Arndt Hartmann, Viktor Gruenwald, Michael Hudecek, Markus Eckstein
NECTIN4 Amplification Is Frequent in Solid Tumors and Predicts Enfortumab Vedotin Response in Metastatic Urothelial Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (20) (2024)
Feng Ren, Alex Aliper, Jian Chen, Heng Zhao, Sujata Rao, Christoph Kuppe, Ivan V Ozerov, Man Zhang, Klaus Witte, Chris Kruse, Vladimir Aladinskiy, Yan Ivanenkov, Daniil Polykovskiy, Yanyun Fu, Eugene Babin, Junwen Qiao, Xing Liang, Zhenzhen Mou, Hui Wang, Frank W Pun, Pedro Torres Ayuso, Alexander Veviorskiy, Dandan Song, Sang Liu, Bei Zhang, Vladimir Naumov, Xiaoqiang Ding, Andrey Kukharenko, Evgeny Izumchenko, Alex Zhavoronkov
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models. Nature biotechnology (2024)
Paul Kiessling, Christoph Kuppe
Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases. Genome medicine 16 (1) (2024)
Mehdi Joodaki, Mina Shaigan, Victor Parra, Roman David Bülow, Christoph Kuppe, David L Hölscher, Mingbo Cheng, James S Nagai, Michaël Goedertier, Nassim Bouteldja, Vladimir Tesar, Jonathan Barratt, Ian Sd Roberts, Rosanna Coppo, Rafael Kramann, Peter Boor, Ivan G Costa
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT). Molecular systems biology 20 (2) (2023)
Zhijian Li, James S Nagai, Christoph Kuppe, Rafael Kramann, Ivan G Costa
scMEGA: single-cell multi-omic enhancer-based gene regulatory network inference. Bioinformatics advances 3 (1) (2023)
Mehdi Joodaki, Mina Shaigan, Victor Parra, Roman David Bülow, Christoph Kuppe, David L Hölscher, Mingbo Cheng, James S Nagai, Michaël Goedertier, Nassim Bouteldja, Vladimir Tesar, Jonathan Barratt, Ian Sd Roberts, Rosanna Coppo, Rafael Kramann, Peter Boor, Ivan G Costa
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT). Molecular systems biology (2023)
Kory J Lavine, Junedh M Amrute, Xin Luo, Vinay Penna, Andrea L Bredemeyer, Tracy Yamawaki, Steven Yang, Farid Kadyrov, Gyu Heo, Sally Shi, Paul Lee, Andrew L Koenig, Christoph Kuppe, Cameran Jones, Benjamin J Kopecky, Sikander Hayat, Pan Ma, Yuriko Terada, Angela Fu, Milena Furtado, Daniel Kreisel, Nathan O Stitziel, Chi-Ming Li, Rafael Kramann, Yongjian Liu, Brandon Ason
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis. Research square (2023)
Kory J Lavine, Junedh M Amrute, Xin Luo, Vinay Penna, Andrea L Bredemeyer, Tracy Yamawaki, Steven Yang, Farid Kadyrov, Gyu Heo, Sally Shi, Paul Lee, Andrew L Koenig, Christoph Kuppe, Cameran Jones, Benjamin J Kopecky, Sikander Hayat, Pan Ma, Yuriko Terada, Angela Fu, Milena Furtado, Daniel Kreisel, Nathan O Stitziel, Chi-Ming Li, Rafael Kramann, Yongjian Liu, Brandon Ason
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis. Research square (2023)
Mehdi Joodaki, Mina Shaigan, Victor Parra, Roman David Bülow, Christoph Kuppe, David L Hölscher, Mingbo Cheng, James S Nagai, Michaël Goedertier, Nassim Bouteldja, Vladimir Tesar, Jonathan Barratt, Ian Sd Roberts, Rosanna Coppo, Rafael Kramann, Peter Boor, Ivan G Costa
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT). Molecular systems biology 20 (2) (2023)
Mehdi Joodaki, Mina Shaigan, Victor Parra, Roman David Bülow, Christoph Kuppe, David L Hölscher, Mingbo Cheng, James S Nagai, Michaël Goedertier, Nassim Bouteldja, Vladimir Tesar, Jonathan Barratt, Ian Sd Roberts, Rosanna Coppo, Rafael Kramann, Peter Boor, Ivan G Costa
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT). Molecular systems biology 20 (2) (2023)
Mehdi Joodaki, Mina Shaigan, Victor Parra, Roman David Bülow, Christoph Kuppe, David L Hölscher, Mingbo Cheng, James S Nagai, Michaël Goedertier, Nassim Bouteldja, Vladimir Tesar, Jonathan Barratt, Ian Sd Roberts, Rosanna Coppo, Rafael Kramann, Peter Boor, Ivan G Costa
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT). Molecular systems biology (2023)
Kim van Kuijk, Ian R McCracken, Renée J H A Tillie, S E J Asselberghs, Dlzar A Kheder, S Muitjens, Han Jin, R S Taylor, R Wichers Schreur, Christoph Kuppe, Ross Dobie, Prakash Ramachandran, Marion J J Gijbels, Lieve Temmerman, Phoebe M Kirkwood, J Luyten, Yanming Li, Heidi Noels, Pieter G Goossens, John R Wilson-Kanamori, Leon J Schurgers, Y H Shen, Barend M E Mees, Erik A L Biessen, Neil Cowan Henderson, Rafael Kramann, Andrew H Baker, Judith C Sluimer
Human and murine fibroblast single cell transcriptomics reveals fibroblast clusters are differentially affected by ageing, and serum cholesterol. Cardiovascular research (2023)
Eleni Stamellou, Shipra Agrawal, Florian Siegerist, Marc Buse, Christoph Kuppe, Tim Lange, Eva Miriam Buhl, Jessica Alam, Thiago Strieder, Peter Boor, Tammo Ostendorf, Hermann-Josef Gröne, Jürgen Floege, William E Smoyer, Nicole Endlich, Marcus J Moeller
Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple species. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2023)
Dominik Kylies, Marina Zimmermann, Fabian Haas, Maria Schwerk, Malte Kuehl, Michael Brehler, Jan Czogalla, Lola C Hernandez C, Leonie Konczalla, Yusuke Okabayashi, Julia Menzel, Ilka Edenhofer, Sam Mezher, Hande Aypek, Bernhard Dumoulin, Hui Wu, Smilla Hofmann, Oliver Kretz, Nicola Wanner, Nicola M Tomas, Susanne Krasemann, Markus Glatzel, Christoph Kuppe, Rafael Kramann, Bella Banjanin, Rebekka K Schneider, Christopher Urbschat, Petra Clara Arck, Nicola Gagliani, Marc van Zandvoort, Thorsten Wiech, Florian Grahammer, Pablo J Sáez, Milagros N Wong, Stefan Bonn, Tobias B Huber, Victor G Puelles
Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens. Nature nanotechnology (2023)
Julian Petersen, Lukas Englmaier, Artem V Artemov, Irina Poverennaya, Ruba Mahmoud, Thibault Bouderlique, Markéta Tesařová, Ruslan M Deviatiiarov, Anett Szilvásy-Szabó, Evgeny E Akkuratov, David Pajuelo Reguera, Hugo Zeberg, Marketa Kaucka, Maria Eleni Kastriti, Jan Krivanek, Tomasz W Radaszkiewicz, Kristína Gömöryová, Sarah Knauth, David Potesil, Zbynek Zdrahal, Ranjani Sri Ganji, Anna Grabowski, Eva Miriam Buhl, Tomas Zikmund, Michaela Kavkova, Håkan Axelson, David Lindgren, Rafael Kramann, Christoph Kuppe, Ferenc Erdélyi, Zoltán Máté, Gábor Szabó, Till Koehne, Tibor Harkany, Kaj Fried, Josef Kaiser, Peter Boor, Csaba Fekete, Jan Rozman, Petr Kasparek, Jan Prochazka, Radislav Sedlacek, Vitezslav Bryja, Oleg Gusev, Igor Adameyko
A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology. Nature communications 14 (1) (2023)
Kim van Kuijk, Ian R McCracken, Renée J H A Tillie, S E J Asselberghs, Dlzar A Kheder, S Muitjens, Han Jin, R S Taylor, R Wichers Schreur, Christoph Kuppe, Ross Dobie, Prakash Ramachandran, Marion J J Gijbels, Lieve Temmerman, Phoebe M Kirkwood, J Luyten, Yanming Li, Heidi Noels, Pieter G Goossens, John R Wilson-Kanamori, Leon J Schurgers, Y H Shen, Barend M E Mees, Erik A L Biessen, Neil Cowan Henderson, Rafael Kramann, Andrew H Baker, Judith C Sluimer
Human and murine fibroblast single cell transcriptomics reveals fibroblast clusters are differentially affected by ageing, and serum cholesterol. Cardiovascular research (2023)
Christoph Kuppe, Rafael Kramann
A spatially resolved atlas of healthy and injured kidney cell states. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2023)
Kory J Lavine, Junedh M Amrute, Xin Luo, Vinay Penna, Andrea L Bredemeyer, Tracy Yamawaki, Steven Yang, Farid Kadyrov, Gyu Heo, Sally Shi, Paul Lee, Andrew L Koenig, Christoph Kuppe, Cameran Jones, Benjamin J Kopecky, Sikander Hayat, Pan Ma, Yuriko Terada, Angela Fu, Milena Furtado, Daniel Kreisel, Nathan O Stitziel, Chi-Ming Li, Rafael Kramann, Yongjian Liu, Brandon Ason
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis. Research square (2023)
Junedh M Amrute, Lulu Lai, Pan Ma, Andrew L Koenig, Kenji Kamimoto, Andrea L Bredemeyer, Thirupura S Shankar, Christoph Kuppe, Farid F Kadyrov, Linda J Schulte, Dylan Stoutenburg, Benjamin J Kopecky, Sutip Navankasattusas, Joseph R Visker, Samantha A Morris, Rafael Kramann, Florian Leuschner, Douglas L Mann, Stavros G Drakos, Kory J Lavine
Defining cardiac functional recovery in end-stage heart failure at single-cell resolution. Nature cardiovascular research 2 (4) (2023)
Julian Petersen, Lukas Englmaier, Artem V Artemov, Irina Poverennaya, Ruba Mahmoud, Thibault Bouderlique, Markéta Tesařová, Ruslan M Deviatiiarov, Anett Szilvásy-Szabó, Evgeny E Akkuratov, David Pajuelo Reguera, Hugo Zeberg, Marketa Kaucka, Maria Eleni Kastriti, Jan Krivanek, Tomasz W Radaszkiewicz, Kristína Gömöryová, Sarah Knauth, David Potesil, Zbynek Zdrahal, Ranjani Sri Ganji, Anna Grabowski, Eva Miriam Buhl, Tomas Zikmund, Michaela Kavkova, Håkan Axelson, David Lindgren, Rafael Kramann, Christoph Kuppe, Ferenc Erdélyi, Zoltán Máté, Gábor Szabó, Till Koehne, Tibor Harkany, Kaj Fried, Josef Kaiser, Peter Boor, Csaba Fekete, Jan Rozman, Petr Kasparek, Jan Prochazka, Radislav Sedlacek, Vitezslav Bryja, Oleg Gusev, Igor Adameyko
Author Correction: A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology. Nature communications 14 (1) (2023)
Zhijian Li, James S Nagai, Christoph Kuppe, Rafael Kramann, Ivan G Costa
scMEGA: single-cell multi-omic enhancer-based gene regulatory network inference. Bioinformatics advances 3 (1) (2023)
Kim van Kuijk, Ian R McCracken, Renée J H A Tillie, S E J Asselberghs, Dlzar A Kheder, S Muitjens, Han Jin, R S Taylor, R Wichers Schreur, Christoph Kuppe, Ross Dobie, Prakash Ramachandran, Marion J J Gijbels, Lieve Temmerman, Phoebe M Kirkwood, J Luyten, Yanming Li, Heidi Noels, Pieter G Goossens, John R Wilson-Kanamori, Leon J Schurgers, Y H Shen, Barend M E Mees, Erik A L Biessen, Neil Cowan Henderson, Rafael Kramann, Andrew H Baker, Judith C Sluimer
Human and murine fibroblast single cell transcriptomics reveals fibroblast clusters are differentially affected by ageing, and serum cholesterol. Cardiovascular research (2023)
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S H Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R Zecchini, Sabrina H Rossi, Charles E Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent J Gnanapragasam, Anne Y Warren, Grant D Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression. Nature communications 13 (1) (2022)
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S H Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R Zecchini, Sabrina H Rossi, Charles E Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent J Gnanapragasam, Anne Y Warren, Grant D Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression. Nature communications 13 (1) (2022)
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S H Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R Zecchini, Sabrina H Rossi, Charles E Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent J Gnanapragasam, Anne Y Warren, Grant D Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression. Nature communications 13 (1) (2022)
Yaoxian Xu, Christoph Kuppe, Javier Perales-Patón, Sikander Hayat, Jennifer Kranz, Ali T Abdallah, James Nagai, Zhijian Li, Fabian Peisker, Turgay Saritas, Maurice Halder, Sylvia Menzel, Konrad Hoeft, Annegien Kenter, Hyojin Kim, Claudia R C van Roeyen, Michael Lehrke, Julia Moellmann, Thimoteus Speer, Eva Miriam Buhl, Remco Hoogenboezem, Peter Boor, Jitske Jansen, Cordula Knopp, Ingo Kurth, Bart Smeets, Eric M J Bindels, Marlies E J Reinders, Carla Baan, Joost H Gribnau, Ewout J Hoorn, Joachim Steffens, Tobias B Huber, Ivan G Costa, Jürgen Floege, Rebekka K Schneider, Julio Saez-Rodriguez, Benjamin S Freedman, Rafael Kramann
Adult human kidney organoids originate from CD24 + cells and represent an advanced model for adult polycystic kidney disease. Nature genetics 54 (11) (2022)
Jitske Jansen, Bartholomeus T van den Berge, Martijn van den Broek, Rutger J Maas, Deniz Daviran, Brigith Willemsen, Rona Roverts, Marit van der Kruit, Christoph Kuppe, Katharina C Reimer, Gianluca Di Giovanni, Fieke Mooren, Quincy Nlandu, Helmer Mudde, Roy Wetzels, Dirk den Braanker, Naomi Parr, James S Nagai, Vedran Drenic, Ivan G Costa, Eric Steenbergen, Tom Nijenhuis, Henry B Dijkman, Nicole Endlich, Nicole C A J van de Kar, Rebekka K Schneider, Jack F M Wetzels, Anat Akiva, Johan van der Vlag, Rafael Kramann, Michiel F Schreuder, Bart Smeets
Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling. Development (Cambridge, England) 149 (9) (2022)
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S H Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R Zecchini, Sabrina H Rossi, Charles E Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent J Gnanapragasam, Anne Y Warren, Grant D Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression. Nature communications 13 (1) (2022)
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S H Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R Zecchini, Sabrina H Rossi, Charles E Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent J Gnanapragasam, Anne Y Warren, Grant D Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression. Nature communications 13 (1) (2022)
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S H Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R Zecchini, Sabrina H Rossi, Charles E Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent J Gnanapragasam, Anne Y Warren, Grant D Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression. Nature communications 13 (1) (2022)
Fabian Peisker, Maurice Halder, James S Nagai, Susanne Ziegler, Nadine Kaesler, Konrad Hoeft, Ronghui Li, Eric M J Bindels, Christoph Kuppe, Julia Moellmann, Michael Lehrke, Christian Stoppe, Michael T Schaub, Rebekka K Schneider, Ivan G Costa, Rafael Kramann
Mapping the cardiac vascular niche in heart failure. Nature communications 13 (1) (2022)
Marco Sciacovelli, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S H Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt, Dylan Gerard Ryan, Timothy Young, Vincent R Zecchini, Sabrina H Rossi, Charles E Massie, Caroline Lohoff, Maria Masid, Vassily Hatzimanikatis, Christoph Kuppe, Alex Von Kriegsheim, Rafael Kramann, Vincent J Gnanapragasam, Anne Y Warren, Grant D Stewart, Ayelet Erez, Sakari Vanharanta, Julio Saez-Rodriguez, Christian Frezza
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression. Nature communications 13 (1) (2022)
Christoph Kuppe, Ricardo Omar Ramirez Flores, Zhijian Li, Sikander Hayat, Rebecca T Levinson, Xian Liao, Monica T Hannani, Jovan Tanevski, Florian Wünnemann, James S Nagai, Maurice Halder, David Schumacher, Sylvia Menzel, Gideon Schäfer, Konrad Hoeft, Mingbo Cheng, Susanne Ziegler, Xiaoting Zhang, Fabian Peisker, Nadine Kaesler, Turgay Saritas, Yaoxian Xu, Astrid Kassner, Jan Gummert, Michiel Morshuis, Junedh M Amrute, Rogier J A Veltrop, Peter Boor, Karin Klingel, Linda W Van Laake, Aryan Vink, Remco M Hoogenboezem, Eric M J Bindels, Leon J Schurgers, Susanne Sattler, Denis Schapiro, Rebekka K Schneider, Kory J Lavine, Hendrik Milting, Ivan G Costa, Julio Saez-Rodriguez, Rafael Kramann
Spatial multi-omic map of human myocardial infarction. Nature 608 (7924) (2022)
Aurélien J F Dugourd, Christoph Kuppe, Marco Sciacovelli, Enio Gjerga, Attila Gabor, Kristina B Emdal, Vitor Vieira, Dorte B Bekker-Jensen, Jennifer Kranz, Eric M J Bindels, Ana S H Costa, Abel Sousa, Pedro Beltrao, Miguel Rocha, Jesper Velgaard Olsen, Christian Frezza, Rafael Kramann, Julio Saez-Rodriguez
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses. Molecular systems biology 17 (1) (2021)
Zhijian Li, Christoph Kuppe, Susanne Ziegler, Mingbo Cheng, Nazanin Kabgani, Sylvia Menzel, Martin Zenke, Rafael Kramann, Ivan G Costa
Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen. Nature communications 12 (1) (2021)
Christoph Kuppe, Mahmoud M Ibrahim, Jennifer Kranz, Xiaoting Zhang, Susanne Ziegler, Javier Perales-Patón, Jitske Jansen, Katharina C Reimer, James R Smith, Ross Dobie, John R Wilson-Kanamori, Maurice Halder, Yaoxian Xu, Nazanin Kabgani, Nadine Kaesler, Martin Klaus, Lukas Gernhold, Victor G Puelles, Tobias B Huber, Peter Boor, Sylvia Menzel, Remco M Hoogenboezem, Eric M J Bindels, Joachim Steffens, Jürgen Floege, Rebekka K Schneider, Julio Saez-Rodriguez, Neil Cowan Henderson, Rafael Kramann
Decoding myofibroblast origins in human kidney fibrosis. Nature 589 (7841) (2020)