Christopher R M Asquith

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 26

Top Topics

Oxide Nanoparticles

Structure Activity Relationship

Top Venues

Molecules (Basel, Switzerland)

bioRxiv : the preprint server for biology

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Andrew A Bieberich, Christopher R M Asquith
Utilization of Supervised Machine Learning to Understand Kinase Inhibitor Toxophore Profiles. International journal of molecular sciences 24 (6) (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Andrew A Bieberich, Christopher R M Asquith
Utilization of Supervised Machine Learning to Understand Kinase Inhibitor Toxophore Profiles. International journal of molecular sciences 24 (6) (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I Wells, Alison D Axtman, David Harold Drewry, Graham J Tizzard, Antti Poso, Timothy M Willson, Gary L Johnson
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships. bioRxiv : the preprint server for biology (2023)
Andrew A Bieberich, Christopher R M Asquith
Utilization of Supervised Machine Learning to Understand Kinase Inhibitor Toxophore Profiles. International journal of molecular sciences 24 (6) (2023)
Andreas S Kalogirou, Hans J Oh, Christopher R M Asquith
The Synthesis and Biological Applications of the 1,2,3-Dithiazole Scaffold. Molecules (Basel, Switzerland) 28 (7) (2023)
Christopher R M Asquith, Louisa Temme, Michael P East, Tuomo Laitinen, Julie E Pickett, Frank E Kwarcinski, Parvathi Sinha, Carrow I Wells, Gary L Johnson, Reena Zutshi, David Harold Drewry
Identification of 4-Anilinoquin(az)oline as a Cell-Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype. ChemMedChem 17 (12) (2022)
Nathan H Murray, Christopher R M Asquith, Zixiang Fang, Michael P East, Naomi Ptak, Robert W Smith, James D Vasta, Chad A Zimprich, Cesear R Corona, Matthew B Robers, Gary L Johnson, Craig A Bingman, David J Pagliarini
Small-molecule inhibition of the archetypal UbiB protein COQ8. Nature chemical biology (2022)
Benjamin J Eduful, Sean N O'Byrne, Louisa Temme, Christopher R M Asquith, Yi Liang, Alfredo Picado, Joseph R Pilotte, Mohammad Anwar Hossain, Carrow I Wells, William J Zuercher, Carolina M C Catta-Preta, Priscila Zonzini Ramos, André de S Santiago, Rafael M Couñago, Christopher G Langendorf, Kévin Nay, Jonathan S Oakhill, Thomas L Pulliam, Chenchu Lin, Dominik Awad, Timothy M Willson, Daniel E Frigo, John W Scott, David Harold Drewry
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes. Journal of medicinal chemistry 64 (15) (2021)
Carrow I Wells, Hassan Al-Ali, David M Andrews, Christopher R M Asquith, Alison D Axtman, Ivan Dikic, Daniel V Ebner, Peter Ettmayer, Christian Fischer, Mathias Frederiksen, Robert E Futrell, Nathanael S Gray, Stephanie B Hatch, Stefan Knapp, Ulrich Lücking, Michael Michaelides, Caitlin E Mills, Susanne Müller, Dafydd Owen, Alfredo Picado, Kumar S Saikatendu, Martin Schröder, Alexandra Stolz, Mariana Tellechea, Brandon J Turunen, Santiago Vilar, Jinhua Wang, William J Zuercher, Timothy M Willson, David Harold Drewry
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. International journal of molecular sciences 22 (2) (2021)
Pei-Tzu Huang, Sirle Saul, Shirit Einav, Christopher R M Asquith
Optimization of 4-Anilinoquinolines as Dengue Virus Inhibitors. Molecules (Basel, Switzerland) 26 (23) (2021)
Andreas S Kalogirou, Michael P East, Tuomo Laitinen, Chad D Torrice, Kaitlyn A Maffuid, David Harold Drewry, Panayiotis A Koutentis, Gary L Johnson, Daniel J Crona, Christopher R M Asquith
Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors. Molecules (Basel, Switzerland) 26 (19) (2021)
Christopher R M Asquith, Graham J Tizzard, James M Bennett, Carrow I Wells, Jonathan M Elkins, Timothy M Willson, Antti Poso, Tuomo Laitinen
Targeting the Water Network in Cyclin G-Associated Kinase (GAK) with 4-Anilino-quin(az)oline Inhibitors. ChemMedChem 15 (13) (2020)
Christopher R M Asquith, Tuomo Laitinen, Carrow I Wells, Graham J Tizzard, William J Zuercher
New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K). Molecules (Basel, Switzerland) 25 (7) (2020)
Christopher R M Asquith, Tuomo Laitinen, James M Bennett, Carrow I Wells, Jonathan M Elkins, William J Zuercher, Graham J Tizzard, Antti Poso
Design and Analysis of the 4-Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure-Activity Relationships. ChemMedChem 15 (1) (2019)
Christopher R M Asquith, Kaitlyn A Maffuid, Tuomo Laitinen, Chad D Torrice, Graham J Tizzard, Daniel J Crona, William J Zuercher
Targeting an EGFR Water Network with 4-Anilinoquin(az)oline Inhibitors for Chordoma. ChemMedChem 14 (19) (2019)
Christopher R M Asquith, Tuomo Laitinen, Lidia S Konstantinova, Graham Tizzard, Antti Poso, Oleg A Rakitin, Regina Hofmann-Lehmann, Stephen T Hilton
Investigation of the Pentathiepin Functionality as an Inhibitor of Feline Immunodeficiency Virus (FIV) via a Potential Zinc Ejection Mechanism, as a Model for HIV Infection. ChemMedChem 14 (4) (2019)
Christopher R M Asquith, Benedict-Tilman Berger, Jing Wan, James M Bennett, Stephen J Capuzzi, Daniel J Crona, David Harold Drewry, Michael P East, Jonathan M Elkins, Oleg Fedorov, Paulo H Godoi, Debra M Hunter, Stefan Knapp, Susanne Müller, Chad D Torrice, Carrow I Wells, H Shelton Earp, Timothy M Willson, William J Zuercher
SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK). Journal of medicinal chemistry 62 (5) (2019)
María Ayelén Carabajal, Christopher R M Asquith, Tuomo Laitinen, Graham J Tizzard, Lucía Yim, Analía Rial, José A Chabalgoity, William J Zuercher, Eleonora García Véscovi
Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System. Antimicrobial agents and chemotherapy 64 (1) (2019)
Christopher R M Asquith, James M Bennett, Lianyong Su, Tuomo Laitinen, Jonathan M Elkins, Julie E Pickett, Carrow I Wells, Zengbiao Li, Timothy M Willson, William J Zuercher
Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK). Molecules (Basel, Switzerland) 24 (22) (2019)
Christopher R M Asquith, Paulo H C Godoi, Rafael M Couñago, Tuomo Laitinen, John W Scott, Christopher G Langendorf, Jonathan S Oakhill, David H Drewry, William J Zuercher, Panayiotis A Koutentis, Timothy M Willson, Andreas S Kalogirou
1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors. Molecules (Basel, Switzerland) 23 (5) (2018)
Christopher R M Asquith, Tuomo Laitinen, James M Bennett, Paulo H Godoi, Michael P East, Graham J Tizzard, Lee M Graves, Gary L Johnson, Ronna E Dornsife, Carrow I Wells, Jonathan M Elkins, Timothy M Willson, William J Zuercher
Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem 13 (1) (2017)
Christopher R M Asquith, Lidia S Konstantinova, Tuomo Laitinen, Marina Luisa Meli, Antti Poso, Oleg A Rakitin, Regina Hofmann-Lehmann, Stephen T Hilton
Evaluation of Substituted 1,2,3-Dithiazoles as Inhibitors of the Feline Immunodeficiency Virus (FIV) Nucleocapsid Protein via a Proposed Zinc Ejection Mechanism. ChemMedChem 11 (19) (2016)