Janet R Kumita (Janet Kumita)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 26

Top Topics

Molecular Dynamics Simulations

Colorectal Cancer Screening

Protein Protein

Top Venues

Science advances

Communications biology

This page only lists publications with an associated author ORCID identifier.

Publications

Greta Šneiderienė, Magdalena A Czekalska, Catherine K Xu, Akhila K Jayaram, Georg Krainer, William E Arter, Quentin A E Peter, Marta Castellana-Cruz, Kadi Liis Saar, Aviad Levin, Thomas Mueller, Sebastian Fiedler, Sean R A Devenish, Heike Fiegler, Janet R Kumita, Tuomas P J Knowles
α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes. ACS nano 18 (27) (2024)
Anupam Banerjee, Samuel Mathew, Mohsin M Naqvi, Sema Zeynep Yilmaz, Maria Zacharopoulou, Pemra Doruker, Janet R Kumita, Shang-Hua Yang, Mert Gür, Laura S Itzhaki, Reuven Gordon, Ivet Bahar
Influence of point mutations on PR65 conformational adaptability: Insights from molecular simulations and nanoaperture optical tweezers. Science advances 10 (22) (2024)
Anupam Banerjee, Samuel Mathew, Mohsin M Naqvi, Sema Zeynep Yilmaz, Maria Zacharopoulou, Pemra Doruker, Janet R Kumita, Shang-Hua Yang, Mert Gür, Laura S Itzhaki, Reuven Gordon, Ivet Bahar
Influence of point mutations on PR65 conformational adaptability: Insights from molecular simulations and nanoaperture optical tweezers. Science advances 10 (22) (2024)
Greta Šneiderienė, Magdalena A Czekalska, Catherine K Xu, Akhila K Jayaram, Georg Krainer, William E Arter, Quentin A E Peter, Marta Castellana-Cruz, Kadi Liis Saar, Aviad Levin, Thomas Mueller, Sebastian Fiedler, Sean R A Devenish, Heike Fiegler, Janet R Kumita, Tuomas P J Knowles
α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes. ACS nano 18 (27) (2024)
Anupam Banerjee, Samuel Mathew, Mohsin M Naqvi, Sema Zeynep Yilmaz, Maria Zacharopoulou, Pemra Doruker, Janet R Kumita, Shang-Hua Yang, Mert Gür, Laura S Itzhaki, Reuven Gordon, Ivet Bahar
Influence of point mutations on PR65 conformational adaptability: Insights from molecular simulations and nanoaperture optical tweezers. Science advances 10 (22) (2024)
Greta Šneiderienė, Magdalena A Czekalska, Catherine K Xu, Akhila K Jayaram, Georg Krainer, William E Arter, Quentin A E Peter, Marta Castellana-Cruz, Kadi Liis Saar, Aviad Levin, Thomas Mueller, Sebastian Fiedler, Sean R A Devenish, Heike Fiegler, Janet R Kumita, Tuomas P J Knowles
α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes. ACS nano 18 (27) (2024)
Anupam Banerjee, Samuel Mathew, Mohsin M Naqvi, Sema Zeynep Yilmaz, Maria Zacharopoulou, Pemra Doruker, Janet R Kumita, Shang-Hua Yang, Mert Gür, Laura S Itzhaki, Reuven Gordon, Ivet Bahar
Influence of point mutations on PR65 conformational adaptability: Insights from molecular simulations and nanoaperture optical tweezers. Science advances 10 (22) (2024)
Greta Šneiderienė, Magdalena A Czekalska, Catherine K Xu, Akhila K Jayaram, Georg Krainer, William E Arter, Quentin A E Peter, Marta Castellana-Cruz, Kadi Liis Saar, Aviad Levin, Thomas Mueller, Sebastian Fiedler, Sean R A Devenish, Heike Fiegler, Janet R Kumita, Tuomas P J Knowles
α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes. ACS nano (2024)
Ivet Bahar, Anupam Banerjee, Samuel Mathew, Mohsin M Naqvi, Sema Yilmaz, Maria Zachoropoulou, Pemra Doruker, Janet R Kumita, Shang-Hua Yang, Mert Gur, Laura S Itzhaki, Reuven Gordon
Influence of Point Mutations on PR65 Conformational Adaptability: Insights from Nanoaperture Optical Tweezer Experiments and Molecular Simulations. Research square (2023)
Catherine K Xu, Marta Castellana-Cruz, Serene W Chen, Zhen Du, Georg Meisl, Aviad Levin, Benedetta Mannini, Laura S Itzhaki, Tuomas P J Knowles, Christopher M Dobson, Nunilo Cremades, Janet R Kumita
The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity. Molecules (Basel, Switzerland) 27 (4) (2022)
Rosie Bell, Rebecca J Thrush, Marta Castellana-Cruz, Marc Oeller, Roxine Staats, Aishwarya Nene, Patrick Flagmeier, Catherine K Xu, Sandeep Satapathy, Céline Galvagnion, Mark R Wilson, Christopher M Dobson, Janet R Kumita, Christopher M Dobson
N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates. Biochemistry 61 (17) (2022)
Rodrigo Cataldi, Sean Chia, Katarina Pisani, Francesco Simone Ruggeri, Catherine K Xu, Tomas Šneideris, Michele Perni, Sunehera Sarwat, Priyanka Joshi, Janet R Kumita, Sara Linse, Johnny Habchi, Tuomas P J Knowles, Benedetta Mannini, Christopher M Dobson, Christopher M Dobson
Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers. Communications biology 4 (1) (2021)
Yiping Cao, Jozef Adamcik, Michael Diener, Janet R Kumita, Raffaele Mezzenga
Different Folding States from the Same Protein Sequence Determine Reversible vs Irreversible Amyloid Fate. Journal of the American Chemical Society 143 (30) (2021)
Rodrigo Cataldi, Sean Chia, Katarina Pisani, Francesco Simone Ruggeri, Catherine K Xu, Tomas Šneideris, Michele Perni, Sunehera Sarwat, Priyanka Joshi, Janet R Kumita, Sara Linse, Johnny Habchi, Tuomas P J Knowles, Benedetta Mannini, Christopher M Dobson, Christopher M Dobson
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers. Communications biology 4 (1) (2021)
Ryan Limbocker, Benedetta Mannini, Rodrigo Cataldi, Shianne Chhangur, Aidan K Wright, Ryan P Kreiser, J Alex Albright, Sean Chia, Johnny Habchi, Pietro Sormanni, Janet R Kumita, Francesco Simone Ruggeri, Christopher M Dobson, Fabrizio Chiti, Francesco Antonio Aprile, Christopher M Dobson
Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers. International journal of molecular sciences 21 (12) (2020)
Magdalena Chrabąszczewska, Adam K Sieradzan, Sylwia Rodziewicz-Motowidło, Anders Grubb, Christopher M Dobson, Janet R Kumita, Maciej Kozak
Structural Characterization of Covalently Stabilized Human Cystatin C Oligomers. International journal of molecular sciences 21 (16) (2020)
Jae-Hoon Jung, Antonio D Barbosa, Stephanie Hutin, Janet R Kumita, Mingjun Gao, Dorothee Derwort, Catarina S Silva, Xuelei Lai, Elodie Pierre, Feng Geng, Sol-Bi Kim, Sujeong Baek, Chloe Zubieta, Katja E Jaeger, Philip A Wigge
A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis. Nature 585 (7824) (2020)
William E Arter, Catherine K Xu, Marta Castellana-Cruz, Therese W Herling, Georg Krainer, Kadi Liis Saar, Janet R Kumita, Christopher M Dobson, Tuomas P J Knowles
Rapid Structural, Kinetic, and Immunochemical Analysis of Alpha-Synuclein Oligomers in Solution. Nano letters 20 (11) (2020)
Aurora Diamante, Piyush K Chaturbedy, Pamela J E Rowling, Janet R Kumita, Rohan S Eapen, Stephen H McLaughlin, Marc de la Roche, Albert Perez-Riba, Laura S Itzhaki
Engineering mono- and multi-valent inhibitors on a modular scaffold. Chemical science 12 (3) (2020)
Ryan Limbocker, Benedetta Mannini, Francesco Simone Ruggeri, Roberta Cascella, Catherine K Xu, Michele Perni, Sean Chia, Serene W Chen, Johnny Habchi, Alessandra Bigi, Ryan P Kreiser, Aidan K Wright, J Alex Albright, Tadas Kartanas, Janet R Kumita, Nunilo Cremades, Michael Zasloff, Cristina Cecchi, Tuomas P J Knowles, Fabrizio Chiti, Christopher M Dobson, Christopher M Dobson
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism. Communications biology 3 (1) (2020)
Francesco Simone Ruggeri, Patrick Flagmeier, Janet R Kumita, Georg Meisl, Dimitri Y Chirgadze, Marie N Bongiovanni, Tuomas P J Knowles, Christopher M Dobson
The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils. ACS nano 14 (5) (2020)
Ryan Limbocker, Sean Chia, Francesco S Ruggeri, Michele Perni, Roberta Cascella, Gabriella T Heller, Georg Meisl, Benedetta Mannini, Johnny Habchi, Thomas C T Michaels, Pavan K Challa, Minkoo Ahn, Samuel T Casford, Nilumi Fernando, Catherine K Xu, Nina D Kloss, Samuel I A Cohen, Janet R Kumita, Cristina Cecchi, Michael Zasloff, Sara Linse, Tuomas P J Knowles, Fabrizio Chiti, Michele Vendruscolo, Christopher M Dobson
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes. Nature communications 10 (1) (2019)
Janice S W Ng, Maya A Hanspal, Naunehal S Matharu, Teresa P Barros, Elin K Esbjörner, Mark R Wilson, Justin J Yerbury, Christopher M Dobson, Janet R Kumita
Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis. Biochemistry 58 (39) (2019)
Michele Perni, Patrick Flagmeier, Ryan Limbocker, Roberta Cascella, Francesco Antonio Aprile, Céline Galvagnion, Gabriella T Heller, Georg Meisl, Serene W Chen, Janet R Kumita, Pavan Kumar Challa, Julius B Kirkegaard, Samuel I A Cohen, Benedetta Mannini, Denise Barbut, Ellen A A Nollen, Cristina Cecchi, Nunilo Cremades, Tuomas P J Knowles, Fabrizio Chiti, Michael Zasloff, Christopher M Dobson, Christopher M Dobson
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine. ACS chemical biology 13 (8) (2018)
Karen Stroobants, Janet R Kumita, Nicola J Harris, Dimitri Y Chirgadze, Christopher M Dobson, Paula J Booth, Christopher M Dobson
Amyloid-like Fibrils from an α-Helical Transmembrane Protein. Biochemistry 56 (25) (2017)
Minkoo Ahn, Christopher A Waudby, Ana Bernardo-Gancedo, Erwin De Genst, Anne Dhulesia, Xavier Salvatella, John Christodoulou, Christopher M Dobson, Janet R Kumita
Application of Lysine-specific Labeling to Detect Transient Interactions Present During Human Lysozyme Amyloid Fibril Formation. Scientific reports 7 (1) (2017)