Leila Lo Leggio (L Lo Leggio)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 46

Top Topics

Room Temperature

Staphylococcus Aureus

Crystal Structure

Top Venues

Applied and environmental microbiology

Acta crystallographica. Section F, Structural biology communications

The Journal of biological chemistry

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Andrea Seveso, Scott Mazurkewich, Sanchari Banerjee, Jens-Christian Navarro Poulsen, Leila Lo Leggio, Johan Larsbrink
Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Applied and environmental microbiology 90 (1) (2024)
Andrea Seveso, Scott Mazurkewich, Sanchari Banerjee, Jens-Christian Navarro Poulsen, Leila Lo Leggio, Johan Larsbrink
Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Applied and environmental microbiology 90 (1) (2024)
Andrea Seveso, Scott Mazurkewich, Sanchari Banerjee, Jens-Christian Navarro Poulsen, Leila Lo Leggio, Johan Larsbrink
Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Applied and environmental microbiology (2024)
Gonzalo Nahuel Bidart, David Teze, Charlotte Uldahl Jansen, Eleonora Pasutto, Natalia Putkaradze, Anna-Mamusu Sesay, Folmer Fredslund, Leila Lo Leggio, Olafur Ögmundarson, Sumesh Sukumara, Katrine M Qvortrup, Ditte Hededam Welner
Chemoenzymatic indican for light-driven denim dyeing. Nature communications 15 (1) (2024)
Andrea Seveso, Scott Mazurkewich, Sanchari Banerjee, Jens-Christian Navarro Poulsen, Leila Lo Leggio, Johan Larsbrink
Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Applied and environmental microbiology 90 (1) (2024)
Erna Katharina Wieduwilt, Leila Lo Leggio, Erik Donovan Hedegård
A frontier-orbital view of the initial steps of lytic polysaccharide monooxygenase reactions. Dalton transactions (Cambridge, England : 2003) 53 (13) (2024)
Andrea Seveso, Scott Mazurkewich, Sanchari Banerjee, Jens-Christian Navarro Poulsen, Leila Lo Leggio, Johan Larsbrink
Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Applied and environmental microbiology 90 (1) (2024)
Erna Katharina Wieduwilt, Leila Lo Leggio, Erik Donovan Hedegård
A frontier-orbital view of the initial steps of lytic polysaccharide monooxygenase reactions. Dalton transactions (Cambridge, England : 2003) 53 (13) (2024)
Erna Katharina Wieduwilt, Leila Lo Leggio, Erik Donovan Hedegård
A frontier-orbital view of the initial steps of lytic polysaccharide monooxygenase reactions. Dalton transactions (Cambridge, England : 2003) (2024)
Gonzalo Nahuel Bidart, David Teze, Charlotte Uldahl Jansen, Eleonora Pasutto, Natalia Putkaradze, Anna-Mamusu Sesay, Folmer Fredslund, Leila Lo Leggio, Olafur Ögmundarson, Sumesh Sukumara, Katrine M Qvortrup, Ditte Hededam Welner
Chemoenzymatic indican for light-driven denim dyeing. Nature communications 15 (1) (2024)
Gonzalo Nahuel Bidart, David Teze, Charlotte Uldahl Jansen, Eleonora Pasutto, Natalia Putkaradze, Anna-Mamusu Sesay, Folmer Fredslund, Leila Lo Leggio, Olafur Ögmundarson, Sumesh Sukumara, Katrine M Qvortrup, Ditte Hededam Welner
Chemoenzymatic indican for light-driven denim dyeing. Nature communications 15 (1) (2024)
Tobias Tandrup, Leila Lo Leggio, Flora Meilleur
Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature. Acta crystallographica. Section F, Structural biology communications 79 (Pt 1) (2023)
Scott Mazurkewich, Karoline C Scholzen, Rikke H Brusch, Jens-Christian Navarro Poulsen, Yusuf Theibich, Silvia Hüttner, Lisbeth Olsson, Johan Larsbrink, Leila Lo Leggio
Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans. Acta crystallographica. Section D, Structural biology (2023)
Tobias Tandrup, Leila Lo Leggio, Flora Meilleur
Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature. Acta crystallographica. Section F, Structural biology communications 79 (Pt 1) (2023)
Tobias Tandrup, Leila Lo Leggio, Flora Meilleur
Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature. Acta crystallographica. Section F, Structural biology communications 79 (Pt 1) (2023)
Johan Larsbrink, Leila Lo Leggio
Glucuronoyl esterases - enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass. Essays in biochemistry (2023)
Tobias Tandrup, Leila Lo Leggio, Flora Meilleur
Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature. Acta crystallographica. Section F, Structural biology communications 79 (Pt 1) (2023)
Peicheng Sun, Zhiyu Huang, Sanchari Banerjee, Marco A S Kadowaki, Romy J Veersma, Silvia Magri, Roelant Hilgers, Sebastian J Muderspach, Christophe V F P Laurent, Roland Ludwig, David Cannella, Leila Lo Leggio, Willem J H van Berkel, Mirjam A Kabel
AA16 Oxidoreductases Boost Cellulose-Active AA9 Lytic Polysaccharide Monooxygenases from Myceliophthora thermophila . ACS catalysis 13 (7) (2023)
Tobias Tandrup, Sebastian Jannick Muderspach, Sanchari Banerjee, Gianluca Santoni, Johan Ørskov Ipsen, Cristina Hernández-Rollán, Morten H H Nørholm, Katja Salomon Johansen, Flora Meilleur, Leila Lo Leggio
Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding. IUCrJ 9 (Pt 5) (2022)
Zhiyou Zong, Scott Mazurkewich, Caroline S Pereira, Haohao Fu, Wensheng Cai, Xueguang Shao, Munir S Skaf, Johan Larsbrink, Leila Lo Leggio
Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion. Nature communications 13 (1) (2022)
Sanchari Banerjee, Sebastian J Muderspach, Tobias Tandrup, Kristian Erik Høpfner Frandsen, Raushan K Singh, Johan Ørskov Ipsen, Cristina Hernández-Rollán, Morten H H Nørholm, Morten Jannik Bjerrum, Katja Salomon Johansen, Leila Lo Leggio
Protonation State of an Important Histidine from High Resolution Structures of Lytic Polysaccharide Monooxygenases. Biomolecules 12 (2) (2022)
Camilla S Kristensen, Anders K Varming, Helena A K Leinweber, Karin Hammer, Leila Lo Leggio, Hanne Ingmer, Mogens Kilstrup
Characterization of the genetic switch from phage ɸ13 important for Staphylococcus aureus colonization in humans. MicrobiologyOpen 10 (5) (2022)
Janina Sprenger, Catherine L Lawson, Claes von Wachenfeldt, Leila Lo Leggio, Jannette Carey
Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan. Acta crystallographica. Section F, Structural biology communications 77 (Pt 7) (2021)
Anders Kokkenborg Varming, Kim Krighaar Rasmussen, Zhiyou Zong, Peter Waaben Thulstrup, Mogens Kilstrup, Leila Lo Leggio
Flexible linker modulates the binding affinity of the TP901-1 CI phage repressor to DNA. The FEBS journal (2021)
Daniel Krska, Scott Mazurkewich, Haley A Brown, Yusuf Theibich, Jens-Christian N Poulsen, Adeline L Morris, Nicole M Koropatkin, Leila Lo Leggio, Johan Larsbrink
Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii. Biochemistry 60 (27) (2021)
Janina Sprenger, Jannette Carey, Alexander Schulz, Fleur Drouard, Catherine L Lawson, Claes von Wachenfeldt, Sara Linse, Leila Lo Leggio
Guest-protein incorporation into solvent channels of a protein host crystal (hostal). Acta crystallographica. Section D, Structural biology 77 (Pt 4) (2021)
Sebastian J Muderspach, Folmer Fredslund, Verena Volf, Jens-Christian Navarro Poulsen, Thomas H Blicher, Mads Hartvig Clausen, Kim Krighaar Rasmussen, Kristian B R M Krogh, Kenneth Jensen, Leila Lo Leggio
Engineering the substrate binding site of the hyperthermostable archaeal endo-β-1,4-galactanase from Ignisphaera aggregans. Biotechnology for biofuels 14 (1) (2021)
Radina Tokin, Kristian Erik Høpfner Frandsen, Johan Ørskov Ipsen, Leila Lo Leggio, Mahesha M Poojary, Jean-Guy Berrin, Sacha Grisel, Søren Brander, Poul-Erik Jensen, Katja Salomon Johansen
Inhibition of lytic polysaccharide monooxygenase by natural plant extracts. The New phytologist 232 (3) (2021)
Margit Pedersen, Jesper Tvenge Neergaard, Johan Cassias, Kim Krighaar Rasmussen, Leila Lo Leggio, Kim Sneppen, Karin Hammer, Mogens Kilstrup
Repression of the lysogenic PR promoter in bacteriophage TP901-1 through binding of a CI-MOR complex to a composite OM-OR operator. Scientific reports 10 (1) (2020)
Kim Krighaar Rasmussen, Andrés Palencia, Anders K Varming, Habiba El-Wali, Elisabetta Boeri Erba, Martin Blackledge, Karin Hammer, Torsten Herrmann, Mogens Kilstrup, Leila Lo Leggio, Malene Ringkjøbing Jensen
Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage. Proceedings of the National Academy of Sciences of the United States of America 117 (34) (2020)
Sarela Garcia Santamarina, Corinna Probst, Richard A Festa, Chen Ding, Aaron D Smith, Steven E Conklin, Søren Brander, Lisa N Kinch, Nick V Grishin, Katherine J Franz, Pamela Riggs-Gelasco, Leila Lo Leggio, Katja Salomon Johansen, Dennis J Thiele
A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis. Nature chemical biology 16 (3) (2020)
Aurore Labourel, Kristian E H Frandsen, Feng Zhang, Nicolas Brouilly, Sacha Grisel, Mireille Haon, Luisa Ciano, David Ropartz, Mathieu Fanuel, Francis Martin, David Navarro, Marie-Noëlle Rosso, Tobias Tandrup, Bastien Bissaro, Katja S Johansen, Anastasia Zerva, Paul H Walton, Bernard Henrissat, Leila Lo Leggio, Jean-Guy Berrin
A fungal family of lytic polysaccharide monooxygenase-like copper proteins. Nature chemical biology 16 (3) (2020)
Tobias Tandrup, Theodora Tryfona, Kristian Erik Høpfner Frandsen, Katja Salomon Johansen, Paul Dupree, Leila Lo Leggio
Oligosaccharide Binding and Thermostability of Two Related AA9 Lytic Polysaccharide Monooxygenases. Biochemistry 59 (36) (2020)
Susan Andersen, Marie Sofie Møller, Jens-Christian Navarro Poulsen, Michael J Pichler, Birte Svensson, Leila Lo Leggio, Yong Jun Goh, Maher Abou Hachem
An 1,4-α-Glucosyltransferase Defines a New Maltodextrin Catabolism Scheme in Lactobacillus acidophilus. Applied and environmental microbiology 86 (15) (2020)
Mikiyasu Sakanaka, Morten Ejby Hansen, Aina Gotoh, Toshihiko Katoh, Keisuke Yoshida, Toshitaka Odamaki, Hiroyuki Yachi, Yuta Sugiyama, Shin Kurihara, Junko Hirose, Tadasu Urashima, Jin-Zhong Xiao, Motomitsu Kitaoka, Satoru Fukiya, Atsushi Yokota, Leila Lo Leggio, Maher Abou Hachem, Takane Katayama
Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis. Science advances 5 (8) (2019)
Mia Christine Theilmann, Folmer Fredslund, Birte Svensson, Leila Lo Leggio, Maher Abou Hachem
Substrate preference of an ABC importer corresponds to selective growth on β-(1,6)-galactosides in Bifidobacterium animalis subsp. lactis. The Journal of biological chemistry 294 (31) (2019)
Jenny Arnling Bååth, Scott Mazurkewich, Jens-Christian Navarro Poulsen, Lisbeth Olsson, Leila Lo Leggio, Johan Larsbrink
Structure-function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds. The Journal of biological chemistry 294 (16) (2019)
Kristian Erik Høpfner Frandsen, Morten Tovborg, Christian I Jørgensen, Nikolaj Spodsberg, Marie-Noëlle Rosso, Glyn R Hemsworth, Elspeth F Garman, Geoffrey W Grime, Jens-Christian Navarro Poulsen, Tanveer S Batth, Shingo Miyauchi, Anna Lipzen, Chris Daum, Igor V Grigoriev, Katja S Johansen, Bernard Henrissat, Jean-Guy Berrin, Leila Lo Leggio
Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases. The Journal of biological chemistry 294 (45) (2019)
Søs Torpenholt, Jens-Christian Navarro Poulsen, Sebastian Jannick Muderspach, Leonardo De Maria, Leila Lo Leggio
Structure of Aspergillus aculeatus β-1,4-galactanase in complex with galactobiose. Acta crystallographica. Section F, Structural biology communications 75 (Pt 6) (2019)
Scott Mazurkewich, Jens-Christian Navarro Poulsen, Leila Lo Leggio, Johan Larsbrink
Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components. The Journal of biological chemistry 294 (52) (2019)
Kim Krighaar Rasmussen, Maria Hansen Falkesgaard, Malene Winther, Nikolaj Kulahin Roed, Christine Louise Quistgaard, Marie Nygaard Teisen, Sofie Marie Edslev, David Leander Petersen, Ali Aljubouri, Claus Christensen, Peter Waaben Thulstrup, Leila Lo Leggio, Kaare Teilum, Peter Schledermann Walmod
NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor. Scientific reports 8 (1) (2018)
Tobias Tandrup, Kristian Erik Høpfner Frandsen, Katja S Johansen, Jean-Guy Berrin, Leila Lo Leggio
Recent insights into lytic polysaccharide monooxygenases (LPMOs). Biochemical Society transactions 46 (6) (2018)
Andriy Kryshtafovych, Reinhard Albrecht, Arnaud Baslé, Pedro Bule, Alessandro T Caputo, Ana Luísa Carvalho, Kinlin L Chao, Ron Diskin, Krzysztof Fidelis, Carlos M G A Fontes, Folmer Fredslund, Harry J Gilbert, Celia W Goulding, Marcus D Hartmann, Christopher S Hayes, Osnat Herzberg, Johan C Hill, Andrzej Joachimiak, Gert-Wieland Kohring, Roman I Koning, Leila Lo Leggio, Marco Mangiagalli, Karolina Michalska, John Moult, Shabir Najmudin, Marco Nardini, Valentina Nardone, Didier Ndeh, Thanh-Hong Nguyen, Guido Pintacuda, Sandra Postel, Mark J van Raaij, Pietro Roversi, Amir Shimon, Abhimanyu K Singh, Eric John Sundberg, Kaspars Tars, Nicole Zitzmann, Torsten Schwede
Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016). Proteins (2017)
Alexander Holm Viborg, Takane Katayama, Takatoshi Arakawa, Maher Abou Hachem, Leila Lo Leggio, Motomitsu Kitaoka, Birte Svensson, Shinya Fushinobu
Discovery of α-l-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42. The Journal of biological chemistry 292 (51) (2017)
T J Simmons, Kristian Erik Høpfner Frandsen, Luisa Ciano, T Tryfona, N Lenfant, J C Poulsen, Louis F L Wilson, T Tandrup, M Tovborg, K Schnorr, K S Johansen, B Henrissat, Paul H Walton, Leila Lo Leggio, Paul Dupree
Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates. Nature communications 8 (1) (2017)
Kristian E H Frandsen, Thomas J Simmons, Paul Dupree, Jens-Christian N Poulsen, Glyn R Hemsworth, Luisa Ciano, Esther M Johnston, Morten Tovborg, Katja S Johansen, Pernille von Freiesleben, Laurence Marmuse, Sébastien Fort, Sylvain Cottaz, Hugues Driguez, Bernard Henrissat, Nicolas Lenfant, Floriana Tuna, Amgalanbaatar Baldansuren, Gideon J Davies, Leila Lo Leggio, Paul H Walton
The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases. Nature chemical biology 12 (4) (2016)