Hiroaki Suga (H Suga)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 129

Top Venues

Journal of the American Chemical Society

Nucleic acids research

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

The University of Tokyo

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Tokyo Apr 01 2010

Japan

Professor :: Chemistry, School of Science

The University of Tokyo Apr 01 2003 - Mar 31 2010

Japan

Professor :: Research Center for Advanced Science and Technology

University at Buffalo - The State University of New York - Mar 31 2003

United States

Assistant/Associate Professor :: Chemistry

Massachusetts General Hospital Aug 01 1994 - Aug 01 1997

United States

Post-doctoral Fellow :: Molecular Biology

Education History

Massachusetts Institute of Technology Feb 01 1990 - Feb 20 1994

United States

PHD :: Chemistry

Publications

Maxwell Sigal, Satomi Matsumoto, Adam T Beattie, Takayuki Katoh, Hiroaki Suga
Engineering tRNAs for the Ribosomal Translation of Non-proteinogenic Monomers. Chemical reviews 124 (10) (2024)
Jarrett M Pelton, Joshua E Hochuli, Patric W Sadecki, Takayuki Katoh, Hiroaki Suga, Leslie M Hicks, Eugene N Muratov, Alexander Trospsha, Albert A Bowers
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products. Journal of the American Chemical Society 146 (12) (2024)
Jarrett M Pelton, Joshua E Hochuli, Patric W Sadecki, Takayuki Katoh, Hiroaki Suga, Leslie M Hicks, Eugene N Muratov, Alexander Trospsha, Albert A Bowers
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products. Journal of the American Chemical Society 146 (12) (2024)
Wei Lu, Naohiro Terasaka, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki, Hiroaki Suga
An anticodon-sensing T-boxzyme generates the elongator nonproteinogenic aminoacyl-tRNA in situ of a custom-made translation system for incorporation. Nucleic acids research (2024)
Mikio Imai, Kilian Colas, Hiroaki Suga
Protein Grafting Techniques: From Peptide Epitopes to Lasso-Grafted Neobiologics. ChemPlusChem 89 (8) (2024)
Maxwell Sigal, Satomi Matsumoto, Adam T Beattie, Takayuki Katoh, Hiroaki Suga
Engineering tRNAs for the Ribosomal Translation of Non-proteinogenic Monomers. Chemical reviews (2024)
Sumika Inoue, Dinh Thanh Nguyen, Keisuke Hamada, Rika Okuma, Chikako Okada, Masahiro Okada, Ikuro Abe, Toru Sengoku, Yuki Goto, Hiroaki Suga
De Novo Discovery of Pseudo-Natural Prenylated Macrocyclic Peptide Ligands. Angewandte Chemie (International ed. in English) (2024)
Alexander A Vinogradov, Yue Zhang, Keisuke Hamada, Shunsuke Kobayashi, Kazuhiro Ogata, Toru Sengoku, Yuki Goto, Hiroaki Suga
A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. Journal of the American Chemical Society (2024)
Wei Lu, Naohiro Terasaka, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki, Hiroaki Suga
An anticodon-sensing T-boxzyme generates the elongator nonproteinogenic aminoacyl-tRNA in situ of a custom-made translation system for incorporation. Nucleic acids research 52 (7) (2024)
Jarrett M Pelton, Joshua E Hochuli, Patric W Sadecki, Takayuki Katoh, Hiroaki Suga, Leslie M Hicks, Eugene N Muratov, Alexander Trospsha, Albert A Bowers
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products. Journal of the American Chemical Society (2024)
Jarrett M Pelton, Joshua E Hochuli, Patric W Sadecki, Takayuki Katoh, Hiroaki Suga, Leslie M Hicks, Eugene N Muratov, Alexander Trospsha, Albert A Bowers
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products. Journal of the American Chemical Society 146 (12) (2024)
Ayaka Hayashi, Yuki Goto, Yutaro Saito, Hiroaki Suga, Jumpei Morimoto, Shinsuke Sando
Oxidation-guided and collision-induced linearization assists de novo sequencing of thioether macrocyclic peptides. Chemical communications (Cambridge, England) 60 (70) (2024)
Harry R King, Mark Bycroft, Thanh-Binh Nguyen, Geoff Kelly, Alexander A Vinogradov, Pamela J E Rowling, Katherine Stott, David B Ascher, Hiroaki Suga, Laura S Itzhaki, Katerina Artavanis-Tsakonas
Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Jarrett M Pelton, Joshua E Hochuli, Patric W Sadecki, Takayuki Katoh, Hiroaki Suga, Leslie M Hicks, Eugene N Muratov, Alexander Trospsha, Albert A Bowers
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products. Journal of the American Chemical Society 146 (12) (2024)
Fabian Hink, Julen Aduriz-Arrizabalaga, Xabier Lopez, Hiroaki Suga, David de Sancho, Joseph M Rogers
Mixed Stereochemistry Macrocycle Acts as a Helix-Stabilizing Peptide N-Cap. Journal of the American Chemical Society (2024)
Mikio Imai, Kilian Colas, Hiroaki Suga
Protein Grafting Techniques: From Peptide Epitopes to Lasso-Grafted Neobiologics. ChemPlusChem (2024)
Ayaka Hayashi, Yuki Goto, Yutaro Saito, Hiroaki Suga, Jumpei Morimoto, Shinsuke Sando
Oxidation-guided and collision-induced linearization assists de novo sequencing of thioether macrocyclic peptides. Chemical communications (Cambridge, England) 60 (70) (2024)
Takayuki Katoh, Hiroaki Suga
Fine-tuning the tRNA anticodon arm for multiple/consecutive incorporations of β-amino acids and analogs. Nucleic acids research (2024)
Harry R King, Mark Bycroft, Thanh-Binh Nguyen, Geoff Kelly, Alexander A Vinogradov, Pamela J E Rowling, Katherine Stott, David B Ascher, Hiroaki Suga, Laura S Itzhaki, Katerina Artavanis-Tsakonas
Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Maxwell Sigal, Satomi Matsumoto, Adam T Beattie, Takayuki Katoh, Hiroaki Suga
Engineering tRNAs for the Ribosomal Translation of Non-proteinogenic Monomers. Chemical reviews 124 (10) (2024)
Harry R King, Mark Bycroft, Thanh-Binh Nguyen, Geoff Kelly, Alexander A Vinogradov, Pamela J E Rowling, Katherine Stott, David B Ascher, Hiroaki Suga, Laura S Itzhaki, Katerina Artavanis-Tsakonas
Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Takashi Miura, Kang Ju Lee, Takayuki Katoh, Hiroaki Suga
In Vitro Selection of Macrocyclic l-α/d-α/β/γ-Hybrid Peptides Targeting IFN-γ/IFNGR1 Protein-Protein Interaction. Journal of the American Chemical Society (2024)
Takayuki Katoh, Hiroaki Suga
Fine-tuning the tRNA anticodon arm for multiple/consecutive incorporations of β-amino acids and analogs. Nucleic acids research 52 (11) (2024)
Ayaka Hayashi, Yuki Goto, Yutaro Saito, Hiroaki Suga, Jumpei Morimoto, Shinsuke Sando
Oxidation-guided and collision-induced linearization assists de novo sequencing of thioether macrocyclic peptides. Chemical communications (Cambridge, England) (2024)
Sumika Inoue, Dinh Thanh Nguyen, Keisuke Hamada, Rika Okuma, Chikako Okada, Masahiro Okada, Ikuro Abe, Toru Sengoku, Yuki Goto, Hiroaki Suga
De Novo Discovery of Pseudo-Natural Prenylated Macrocyclic Peptide Ligands. Angewandte Chemie (International ed. in English) 63 (36) (2024)
Takashi Miura, Tika R Malla, Lennart Brewitz, Anthony Tumber, Eidarus Salah, Kang Ju Lee, Naohiro Terasaka, C David Owen, Claire Strain-Damerell, Petra Lukacik, Martin A Walsh, Akane Kawamura, Christopher J Schofield, Takayuki Katoh, Hiroaki Suga
Cyclic β 2,3 -amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease. Bulletin of the Chemical Society of Japan 97 (5) (2024)
Takashi Miura, Tika R Malla, Lennart Brewitz, Anthony Tumber, Eidarus Salah, Kang Ju Lee, Naohiro Terasaka, C David Owen, Claire Strain-Damerell, Petra Lukacik, Martin A Walsh, Akane Kawamura, Christopher J Schofield, Takayuki Katoh, Hiroaki Suga
Cyclic β 2,3 -amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease. Bulletin of the Chemical Society of Japan 97 (5) (2024)
Alexander A Vinogradov, Yue Zhang, Keisuke Hamada, Shunsuke Kobayashi, Kazuhiro Ogata, Toru Sengoku, Yuki Goto, Hiroaki Suga
A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. Journal of the American Chemical Society 146 (12) (2024)
Takashi Miura, Tika R Malla, Lennart Brewitz, Anthony Tumber, Eidarus Salah, Kang Ju Lee, Naohiro Terasaka, C David Owen, Claire Strain-Damerell, Petra Lukacik, Martin A Walsh, Akane Kawamura, Christopher J Schofield, Takayuki Katoh, Hiroaki Suga
Cyclic β 2,3 -amino acids improve the serum stability of macrocyclic peptide inhibitors targeting the SARS-CoV-2 main protease. Bulletin of the Chemical Society of Japan 97 (5) (2024)
Maxwell Sigal, Satomi Matsumoto, Adam T Beattie, Takayuki Katoh, Hiroaki Suga
Engineering tRNAs for the Ribosomal Translation of Non-proteinogenic Monomers. Chemical reviews 124 (10) (2024)
Wei Lu, Naohiro Terasaka, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki, Hiroaki Suga
An anticodon-sensing T-boxzyme generates the elongator nonproteinogenic aminoacyl-tRNA in situ of a custom-made translation system for incorporation. Nucleic acids research 52 (7) (2024)
Jarrett M Pelton, Joshua E Hochuli, Patric W Sadecki, Takayuki Katoh, Hiroaki Suga, Leslie M Hicks, Eugene N Muratov, Alexander Trospsha, Albert A Bowers
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products. Journal of the American Chemical Society 146 (12) (2024)
Harry R King, Mark Bycroft, Thanh-Binh Nguyen, Geoff Kelly, Alexander A Vinogradov, Pamela J E Rowling, Katherine Stott, David B Ascher, Hiroaki Suga, Laura S Itzhaki, Katerina Artavanis-Tsakonas
Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Giulia Franzolin, Serena Brundu, Carina Florina Cojocaru, Aurora Curatolo, Matteo Ponzo, Roberta Mastrantonio, Emiko Mihara, Atsushi Kumanogoh, Hiroaki Suga, Junichi Takagi, Luca Tamagnone, Enrico Giraudo
PlexinB1 inactivation reprograms immune cells in the tumor microenvironment, inhibiting breast cancer growth and metastatic dissemination. Cancer immunology research (2024)
Takashi Miura, Kang Ju Lee, Takayuki Katoh, Hiroaki Suga
In Vitro Selection of Macrocyclic l-α/d-α/β/γ-Hybrid Peptides Targeting IFN-γ/IFNGR1 Protein-Protein Interaction. Journal of the American Chemical Society 146 (26) (2024)
Takashi Miura, Kang Ju Lee, Takayuki Katoh, Hiroaki Suga
In Vitro Selection of Macrocyclic l-α/d-α/β/γ-Hybrid Peptides Targeting IFN-γ/IFNGR1 Protein-Protein Interaction. Journal of the American Chemical Society 146 (26) (2024)
Giulia Franzolin, Serena Brundu, Carina Florina Cojocaru, Aurora Curatolo, Matteo Ponzo, Roberta Mastrantonio, Emiko Mihara, Atsushi Kumanogoh, Hiroaki Suga, Junichi Takagi, Luca Tamagnone, Enrico Giraudo
PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination. Cancer immunology research 12 (9) (2024)
Maxwell Sigal, Satomi Matsumoto, Adam T Beattie, Takayuki Katoh, Hiroaki Suga
Engineering tRNAs for the Ribosomal Translation of Non-proteinogenic Monomers. Chemical reviews 124 (10) (2024)
Alexander A Vinogradov, Yue Zhang, Keisuke Hamada, Shunsuke Kobayashi, Kazuhiro Ogata, Toru Sengoku, Yuki Goto, Hiroaki Suga
A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. Journal of the American Chemical Society 146 (12) (2024)
Takashi Miura, Kang Ju Lee, Takayuki Katoh, Hiroaki Suga
In Vitro Selection of Macrocyclic l-α/d-α/β/γ-Hybrid Peptides Targeting IFN-γ/IFNGR1 Protein-Protein Interaction. Journal of the American Chemical Society 146 (26) (2024)
Wei Lu, Naohiro Terasaka, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki, Hiroaki Suga
An anticodon-sensing T-boxzyme generates the elongator nonproteinogenic aminoacyl-tRNA in situ of a custom-made translation system for incorporation. Nucleic acids research 52 (7) (2024)
Jarrett M Pelton, Joshua E Hochuli, Patric W Sadecki, Takayuki Katoh, Hiroaki Suga, Leslie M Hicks, Eugene N Muratov, Alexander Trospsha, Albert A Bowers
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products. Journal of the American Chemical Society 146 (12) (2024)
Alexander A Vinogradov, Yue Zhang, Keisuke Hamada, Shunsuke Kobayashi, Kazuhiro Ogata, Toru Sengoku, Yuki Goto, Hiroaki Suga
A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. Journal of the American Chemical Society 146 (12) (2024)
Jarrett M Pelton, Joshua E Hochuli, Patric W Sadecki, Takayuki Katoh, Hiroaki Suga, Leslie M Hicks, Eugene N Muratov, Alexander Trospsha, Albert A Bowers
Cheminformatics-Guided Cell-Free Exploration of Peptide Natural Products. Journal of the American Chemical Society 146 (12) (2024)
Alexander A Vinogradov, Yue Zhang, Keisuke Hamada, Shunsuke Kobayashi, Kazuhiro Ogata, Toru Sengoku, Yuki Goto, Hiroaki Suga
A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. Journal of the American Chemical Society 146 (12) (2024)
Alexander A Vinogradov, Yue Zhang, Keisuke Hamada, Shunsuke Kobayashi, Kazuhiro Ogata, Toru Sengoku, Yuki Goto, Hiroaki Suga
A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides. Journal of the American Chemical Society 146 (12) (2024)
Takayuki Katoh, Hiroaki Suga
Fine-tuning the tRNA anticodon arm for multiple/consecutive incorporations of β-amino acids and analogs. Nucleic acids research 52 (11) (2024)
Takayuki Katoh, Hiroaki Suga
Ribosomal incorporation of negatively charged d-α- and N -methyl-l-α-amino acids enhanced by EF-Sep. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Takayuki Katoh, Hiroaki Suga
A comprehensive analysis of translational misdecoding pattern and its implication on genetic code evolution. Nucleic acids research (2023)
Takayuki Katoh, Hiroaki Suga
Ribosomal incorporation of negatively charged d-α- and N -methyl-l-α-amino acids enhanced by EF-Sep. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Hongxue Chen, Takayuki Katoh, Hiroaki Suga
Macrocyclic Peptides Closed by a Thioether-Bipyridyl Unit That Grants Cell Membrane Permeability. ACS bio & med chem Au 3 (5) (2023)
Abhishek Saha, Hiroaki Suga, Ashraf Brik
Combining Chemical Protein Synthesis and Random Nonstandard Peptides Integrated Discovery for Modulating Biological Processes. Accounts of chemical research (2023)
Betsegaw Lemma, Di Zhang, Ganga B Vamisetti, Bryan G Wentz, Hiroaki Suga, Ashraf Brik, Jacek Lubkowski, David Fushman
Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation. Nature communications 14 (1) (2023)
Takayuki Katoh, Hiroaki Suga
Translation initiation with exotic amino acids using EF-P-responsive artificial initiator tRNA. Nucleic acids research (2023)
Yuchen Zhang, Keisuke Hamada, Masayuki Satake, Toru Sengoku, Yuki Goto, Hiroaki Suga
Switching Prenyl Donor Specificities of Cyanobactin Prenyltransferases. Journal of the American Chemical Society (2023)
Xiao Ma, Marina Bakhtina, Irina Shulgina, William A Cantara, Alexandra B Kuzmishin Nagy, Yuki Goto, Hiroaki Suga, Mark P Foster, Karin Musier-Forsyth
Structural basis of tRNAPro acceptor stem recognition by a bacterial trans-editing domain. Nucleic acids research (2023)
Shota Warashina, Hiroki Sato, Maki Zouda, Maiko Takahashi, Yasuhiro Wada, Toby Passioura, Hiroaki Suga, Yasuyoshi Watanabe, Kunio Matsumoto, Hidefumi Mukai
Two-Chain Mature Hepatocyte Growth Factor-Specific Positron Emission Tomography Imaging in Tumors Using 64 Cu-Labeled HiP-8, a Nonstandard Macrocyclic Peptide Probe. Molecular pharmaceutics (2023)
Takashi Miura, Tika R Malla, C David Owen, Anthony Tumber, Lennart Brewitz, Michael A McDonough, Eidarus Salah, Naohiro Terasaka, Takayuki Katoh, Petra Lukacik, Claire Strain-Damerell, Halina Mikolajek, Martin Austin Walsh, Akane Kawamura, Christopher J Schofield, Hiroaki Suga
In vitro selection of macrocyclic peptide inhibitors containing cyclic γ 2,4 -amino acids targeting the SARS-CoV-2 main protease. Nature chemistry (2023)
Takayuki Katoh, Hiroaki Suga
Ribosomal incorporation of negatively charged d-α- and N -methyl-l-α-amino acids enhanced by EF-Sep. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Jun Shi Chang, Alexander A Vinogradov, Yue Zhang, Yuki Goto, Hiroaki Suga
Deep Learning-Driven Library Design for the De Novo Discovery of Bioactive Thiopeptides. ACS central science 9 (11) (2023)
Takayuki Katoh, Hiroaki Suga
Drop-off-reinitiation at the N-termini of nascent peptides and its regulation by IF3, EF-G, and RRF. RNA (New York, N.Y.) (2023)
Takayuki Katoh, Hiroaki Suga
Ribosomal incorporation of negatively charged d-α- and N -methyl-l-α-amino acids enhanced by EF-Sep. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 378 (1871) (2023)
Tatsuya Ikenoue, Miki Oono, Masatomo So, Hodaka Yamakado, Toshiaki Arata, Ryosuke Takahashi, Yasushi Kawata, Hiroaki Suga
A RaPID Macrocyclic Peptide That Inhibits the Formation of α-Synuclein Amyloid Fibrils. Chembiochem : a European journal of chemical biology (2023)
Alexander A Vinogradov, Yue Zhang, Keisuke Hamada, Jun Shi Chang, Chikako Okada, Hirotaka Nishimura, Naohiro Terasaka, Yuki Goto, Kazuhiro Ogata, Toru Sengoku, Hiroyasu Onaka, Hiroaki Suga
De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors. Journal of the American Chemical Society 144 (44) (2022)
Renier H P van Neer, P K Dranchak, L Liu, M Aitha, B Queme, H Kimura, Takayuki Katoh, K P Battaile, S Lovell, James Inglese, Hiroaki Suga
Serum-Stable and Selective Backbone-N-Methylated Cyclic Peptides That Inhibit Prokaryotic Glycolytic Mutases. ACS chemical biology 17 (8) (2022)
Minglong Liu, Miha Sovrovic, Hiroaki Suga, Seino A K Jongkees
Phosphine addition to dehydroalanine for peptide modification. Organic & biomolecular chemistry 20 (15) (2022)
Alexander A Vinogradov, Jun Shi Chang, Hiroyasu Onaka, Yuki Goto, Hiroaki Suga
Accurate Models of Substrate Preferences of Post-Translational Modification Enzymes from a Combination of mRNA Display and Deep Learning. ACS central science 8 (6) (2022)
Masanobu Nagano, Satoshi Ishida, Hiroaki Suga
Inner residues of macrothiolactone in autoinducer peptides I/IV circumvent spontaneous S -to- O acyl transfer to the upstream serine residue. RSC chemical biology 3 (3) (2022)
Takahiro Ono, Kazuhito V Tabata, Yuki Goto, Yutaro Saito, Hiroaki Suga, Hiroyuki Noji, Jumpei Morimoto, Shinsuke Sando
Label-free quantification of passive membrane permeability of cyclic peptides across lipid bilayers: penetration speed of cyclosporin A across lipid bilayers. Chemical science 14 (2) (2022)
Kenya Tajima, Takayuki Katoh, Hiroaki Suga
Drop-off-reinitiation triggered by EF-G-driven mistranslocation and its alleviation by EF-P. Nucleic acids research 50 (5) (2022)
Yue Zhang, Alexander A Vinogradov, Jun Shi Chang, Yuki Goto, Hiroaki Suga
Solid-Phase-Based Synthesis of Lactazole-Like Thiopeptides. Organic letters 24 (43) (2022)
Tomohiro Kuroda, Yichao Huang, Soichiro Nishio, Yuki Goto, Hiroaki Suga
Post-translational backbone-acyl shift yields natural product-like peptides bearing hydroxyhydrocarbon units. Nature chemistry (2022)
Risa Wakabayashi, Marina Kawai, Takayuki Katoh, Hiroaki Suga
In Vitro Selection of Macrocyclic α/β 3 -Peptides against Human EGFR. Journal of the American Chemical Society 144 (40) (2022)
Katsuya Sakai, Nozomi Sugano-Nakamura, Emiko Mihara, Rojas-Chaverra N Marcela, Sayako Watanabe, Hiroki Sato, Ryu Imamura, Dominic Chih-Cheng Voon, Itsuki Sakai, Chihiro Yamasaki, Chise Tateno, Mikihiro Shibata, Hiroaki Suga, Junichi Takagi, Kunio Matsumoto
Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions. Nature biomedical engineering (2022)
Takahiro Ono, Kazuhito V Tabata, Yuki Goto, Yutaro Saito, Hiroaki Suga, Hiroyuki Noji, Jumpei Morimoto, Shinsuke Sando
Label-free quantification of passive membrane permeability of cyclic peptides across lipid bilayers: penetration speed of cyclosporin A across lipid bilayers. Chemical science 14 (2) (2022)
Takayuki Katoh, Hiroaki Suga
In Vitro Selection of Foldamer-Like Macrocyclic Peptides Containing 2-Aminobenzoic Acid and 3-Aminothiophene-2-Carboxylic Acid. Journal of the American Chemical Society 144 (5) (2022)
Ganga B Vamisetti, Abhishek Saha, Yichao J Huang, Rajeshwer Vanjari, Guy Mann, Julia Gutbrod, Nabieh Ayoub, Hiroaki Suga, Ashraf Brik
Selective macrocyclic peptide modulators of Lys63-linked ubiquitin chains disrupt DNA damage repair. Nature communications 13 (1) (2022)
Sayaka Imanishi, Takayuki Katoh, Yizhen Yin, Mituhiro Yamada, Marina Kawai, Hiroaki Suga
In Vitro Selection of Macrocyclic d/l-Hybrid Peptides against Human EGFR. Journal of the American Chemical Society 143 (15) (2021)
Victoria A Haberman, Steven R Fleming, Tina M Leisner, Ana C Puhl, Emerald Feng, Ling Xie, Xian Chen, Yuki Goto, Hiroaki Suga, Leslie V Parise, Dmitri B Kireev, Kenneth H Pearce, Albert A Bowers
Discovery and Development of Cyclic Peptide Inhibitors of CIB1. ACS medicinal chemistry letters 12 (11) (2021)
Emiko Mihara, Satoshi Watanabe, Nasir K Bashiruddin, Nozomi Nakamura, Kyoko Matoba, Yumi Sano, Rumit Maini, Yizhen Yin, Katsuya Sakai, Takao Arimori, Kunio Matsumoto, Hiroaki Suga, Junichi Takagi
Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins. Nature communications 12 (1) (2021)
Alexander A Vinogradov, Masanobu Nagano, Yuki Goto, Hiroaki Suga
Site-Specific Nonenzymatic Peptide S/O-Glutamylation Reveals the Extent of Substrate Promiscuity in Glutamate Elimination Domains. Journal of the American Chemical Society 143 (33) (2021)
Hiroaki Suga
The first year of RSC Chemical Biology - a new journal was born. RSC chemical biology 2 (1) (2021)
Daniel J Ford, Nisharnthi M Duggan, Sarah E Fry, Jorge Ripoll-Rozada, Stijn M Agten, Wenyu Liu, Leo Corcilius, Tilman M Hackeng, Rene van Oerle, Henri M H Spronk, Anneliese S Ashhurst, Vishnu Mini Sasi, Joe A Kaczmarski, Colin J Jackson, Pedro José Barbosa Pereira, Toby Passioura, Hiroaki Suga, Richard J Payne
Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming. Journal of medicinal chemistry 64 (11) (2021)
Wenyu Liu, Simon J de Veer, Yen-Hua Huang, Toru Sengoku, Chikako Okada, Kazuhiro Ogata, Christina N Zdenek, Bryan G Fry, Joakim E Swedberg, Toby Passioura, David J Craik, Hiroaki Suga
An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β-Factor XIIa in a Cyclotide Scaffold. Journal of the American Chemical Society 143 (44) (2021)
Takayuki Katoh, Hiroaki Suga
Consecutive Ribosomal Incorporation of α-Aminoxy/α-Hydrazino Acids with l/d-Configurations into Nascent Peptide Chains. Journal of the American Chemical Society 143 (45) (2021)
Leonardo Puppulin, Daiki Kanayama, Naohiro Terasaka, Katsuya Sakai, Noriyuki Kodera, Kenichi Umeda, Ayumi Sumino, Arin Marchesi, Wei Weilin, Hideo Tanaka, Takeshi Fukuma, Hiroaki Suga, Kunio Matsumoto, Mikihiro Shibata
Macrocyclic Peptide-Conjugated Tip for Fast and Selective Molecular Recognition Imaging by High-Speed Atomic Force Microscopy. ACS applied materials & interfaces 13 (46) (2021)
Makoto Saito, Yasushi Itoh, Fumihiko Yasui, Tsubasa Munakata, Daisuke Yamane, Makoto Ozawa, Risa Ito, Takayuki Katoh, Hirohito Ishigaki, Misako Nakayama, Shintaro Shichinohe, Kenzaburo Yamaji, Naoki Yamamoto, Ai Ikejiri, Tomoko Honda, Takahiro Sanada, Yoshihiro Sakoda, Hiroshi Kida, Thi Quynh Mai Le, Yoshihiro Kawaoka, Kazumasa Ogasawara, Kyoko Tsukiyama-Kohara, Hiroaki Suga, Michinori Kohara
Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models. Nature communications 12 (1) (2021)
Yoshihiko Iwane, Hiroyuki Kimura, Takayuki Katoh, Hiroaki Suga
Uniform affinity-tuning of N-methyl-aminoacyl-tRNAs to EF-Tu enhances their multiple incorporation. Nucleic acids research 49 (19) (2021)
Yuki Goto, Hiroaki Suga
The RaPID Platform for the Discovery of Pseudo-Natural Macrocyclic Peptides. Accounts of chemical research 54 (18) (2021)
Qian Xie, Mareike M Wiedmann, Aishan Zhao, Ivelisse R Pagan, Richard P Novick, Hiroaki Suga, Tom W Muir
Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the Staphylococcus aureus receptor histidine kinase, AgrC. Chemical communications (Cambridge, England) 56 (76) (2021)
Masanobu Nagano, Yichao Huang, Richard Obexer, Hiroaki Suga
One-Pot In Vitro Ribosomal Synthesis of Macrocyclic Depsipeptides. Journal of the American Chemical Society 143 (12) (2021)
Haruka Tsutsumi, Tomohiro Kuroda, Hiroyuki Kimura, Yuki Goto, Hiroaki Suga
Posttranslational chemical installation of azoles into translated peptides. Nature communications 12 (1) (2021)
Kota Koike, Masanobu Nagano, Masahiro Ebihara, Tasuku Hirayama, Mieko Tsuji, Hiroaki Suga, Hideko Nagasawa
Design, Synthesis, and Conformation-Activity Study of Unnatural Bridged Bicyclic Depsipeptides as Highly Potent Hypoxia Inducible Factor-1 Inhibitors and Antitumor Agents. Journal of medicinal chemistry 63 (8) (2020)
Takayuki Katoh, Toru Sengoku, Kunio Hirata, Kazuhiro Ogata, Hiroaki Suga
Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic β-amino acids. Nature chemistry 12 (11) (2020)
Takayuki Katoh, Hiroaki Suga
Ribosomal Elongation of Cyclic γ-Amino Acids using a Reprogrammed Genetic Code. Journal of the American Chemical Society 142 (11) (2020)
Steven R Fleming, Paul M Himes, Swapnil V Ghodge, Yuki Goto, Hiroaki Suga, Albert A Bowers
Exploring the Post-translational Enzymology of PaaA by mRNA Display. Journal of the American Chemical Society 142 (11) (2020)
Satoshi Ishida, Naohiro Terasaka, Takayuki Katoh, Hiroaki Suga
An aminoacylation ribozyme evolved from a natural tRNA-sensing T-box riboswitch. Nature chemical biology 16 (6) (2020)
Christos Tsiamantas, Sunbum Kwon, Joseph M Rogers, Céline Douat, Ivan Huc, Hiroaki Suga
Ribosomal Incorporation of Aromatic Oligoamides as Peptide Sidechain Appendages. Angewandte Chemie (International ed. in English) 59 (12) (2020)
Yichao Huang, Mickal Nawatha, Ido Livneh, Joseph M Rogers, Hao Sun, Sumeet K Singh, Aaron Ciechanover, Ashraf Brik, Hiroaki Suga
Affinity Maturation of Macrocyclic Peptide Modulators of Lys48-Linked Diubiquitin by a Twofold Strategy. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (36) (2020)
Yu Sakurai, Wataru Mizumura, Kenichiro Ito, Kazuhiro Iwasaki, Takayuki Katoh, Yuki Goto, Hiroaki Suga, Hideyoshi Harashima
Improved Stability of siRNA-Loaded Lipid Nanoparticles Prepared with a PEG-Monoacyl Fatty Acid Facilitates Ligand-Mediated siRNA Delivery. Molecular pharmaceutics 17 (4) (2020)

Hiroaki Suga.css-eqlu8i{font-size:small;padding-left:4px;} (H Suga)

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Hiroaki Suga (H Suga)