Tanja Kortemme

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 39

Top Venues

bioRxiv : the preprint server for biology

PLoS computational biology

Nature communications

Science (New York, N.Y.)

University of California San Francisco

EMBL Heidelberg (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California San Francisco

United States

Professor :: Bioengineering & Therapeutic Sciences

University of California San Francisco

United States

Associate Professor :: Bioengineering & Therapeutic Sciences

University of California San Francisco

United States

Assistant Professor :: Bioengineering & Therapeutic Sciences

University of Washington

United States

EMBO & HFSP Postdoctoral Fellow :: Biochemistry

EMBL Heidelberg

Germany

Postdoctoral Fellow (with Luis Serrano) :: Structural & Computational Biology

Education History

EMBL Heidelberg

Germany

PHD :: Biochemistry

University of Hannover

Germany

MSC :: Biophysical Chemistry

University of Hannover

Germany

BSC :: Chemistry / Physical Chemistry

Publications

Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. bioRxiv : the preprint server for biology (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. PLoS computational biology 20 (7) (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. bioRxiv : the preprint server for biology (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. PLoS computational biology 20 (7) (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. PLoS computational biology 20 (7) (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. PLoS computational biology 20 (7) (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. bioRxiv : the preprint server for biology (2024)
Amy B Guo, Deniz Akpinaroglu, Mark J S Kelly, Tanja Kortemme
Deep learning guided design of dynamic proteins. bioRxiv : the preprint server for biology (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. PLoS computational biology 20 (7) (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. bioRxiv : the preprint server for biology (2024)
Amy B Guo, Deniz Akpinaroglu, Mark J S Kelly, Tanja Kortemme
Deep learning guided design of dynamic proteins. bioRxiv : the preprint server for biology (2024)
Lu Hong, Tanja Kortemme
An integrative approach to protein sequence design through multiobjective optimization. bioRxiv : the preprint server for biology (2024)
Anum Azam Glasgow, Helen T Hobbs, Zion R Perry, Malcolm L Wells, Susan Marqusee, Tanja Kortemme
Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor. Nature communications 14 (1) (2023)
Simon Kretschmer, Nicholas T Perry, Yang Zhang, Tanja Kortemme
Multi-input drug-controlled switches of mammalian gene expression based on engineered nuclear hormone receptors. bioRxiv : the preprint server for biology (2023)
Anum Azam Glasgow, Helen T Hobbs, Zion R Perry, Malcolm L Wells, Susan Marqusee, Tanja Kortemme
Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor. Nature communications 14 (1) (2023)
Anum Azam Glasgow, Helen T Hobbs, Zion R Perry, Malcolm L Wells, Susan Marqusee, Tanja Kortemme
Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor. Nature communications 14 (1) (2023)
Simon Kretschmer, Nicholas Perry, Sunny Zhang, Tanja Kortemme
Multi-input Drug-Controlled Switches of Mammalian Gene Expression Based on Engineered Nuclear Hormone Receptors. ACS synthetic biology (2023)
Anum Azam Glasgow, Helen T Hobbs, Zion R Perry, Malcolm L Wells, Susan Marqusee, Tanja Kortemme
Author Correction: Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor. Nature communications 14 (1) (2023)
Simon Kretschmer, Nicholas T Perry, Yang Zhang, Tanja Kortemme
Multi-input drug-controlled switches of mammalian gene expression based on engineered nuclear hormone receptors. bioRxiv : the preprint server for biology (2023)
Anum Azam Glasgow, Helen T Hobbs, Zion R Perry, Malcolm L Wells, Susan Marqusee, Tanja Kortemme
Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor. Nature communications 14 (1) (2023)
Simon Kretschmer, Nicholas T Perry, Yang Zhang, Tanja Kortemme
Multi-input drug-controlled switches of mammalian gene expression based on engineered nuclear hormone receptors. bioRxiv : the preprint server for biology (2023)
Simon Kretschmer, Tanja Kortemme
Advances in the Computational Design of Small-Molecule-Controlled Protein-Based Circuits for Synthetic Biology. Proceedings of the IEEE. Institute of Electrical and Electronics Engineers 110 (5) (2022)
Cody Krivacic, Kale Kundert, Xingjie Pan, Roland A Pache, Lin Liu, Shane O Conchúir, Jeliazko R Jeliazkov, Jeffrey J Gray, Michael C Thompson, Brian K Shoichet, Tanja Kortemme
Accurate positioning of functional residues with robotics-inspired computational protein design. Proceedings of the National Academy of Sciences of the United States of America 119 (11) (2022)
Simon Kretschmer, Tanja Kortemme
Advances in the Computational Design of Small-Molecule-Controlled Protein-Based Circuits for Synthetic Biology. Proceedings of the IEEE. Institute of Electrical and Electronics Engineers 110 (5) (2022)
Simon Kretschmer, Tanja Kortemme
Advances in the Computational Design of Small-Molecule-Controlled Protein-Based Circuits for Synthetic Biology. Proceedings of the IEEE. Institute of Electrical and Electronics Engineers 110 (5) (2022)
Kliment Verba, Meghna Gupta, Caleigh Azumaya, Michelle Moritz, Sergei Pourmal, Amy Diallo, Gregory Merz, Gwendolyn Jang, Mehdi Bouhaddou, Andrea Fossati, Axel Brilot, Devan Diwanji, Evelyn Hernandez, Nadia Herrera, Huong Kratochvil, Victor Lam, Fei Li, Yang Li, Henry C Nguyen, Carlos Nowotny, Tristan Owens, Jessica Peters, Alexandrea N Rizo, Ursula Schulze-Gahmen, Amber Smith, Iris Young, Zanlin Yu, Daniel Asarnow, Christian Billesbølle, Melody G Campbell, Jen Chen, Kuei-Ho Chen, Un Seng Chio, Miles Sasha Dickinson, Loan Doan, Mingliang Jin, Kate Kim, Junrui Li, Yen-Li Li, Edmond Linossi, Yanxin Liu, Megan Lo, Jocelyne Lopez, Kyle Lopez, Adamo Mancino, Frank Moss Iii, Michael Paul, Komal Pawar, Adrian Pelin, Thomas Pospiech, Cristina Puchades, Soumya Remesh, Maliheh Safari, Kaitlin Schaefer, Ming Sun, Mariano Tabios, Aye Thwin, Erron W Titus, Raphael Trenker, Eric Tse, Tsz Kin Martin Tsui, Feng Feng, Kaihua Zhang, Yang Zhang, Jianhua Zhao, Fengbo Zhou, Yuan Zhou, Lorena Zuliani-Alvarez, David A Agard, Yifan Cheng, James Fraser, Natalia Jura, Tanja Kortemme, Aashish Manglik, Daniel R Southworth, Robert M Stroud, Danielle Swaney, Nevan J Krogan, Adam Frost, Oren S Rosenberg
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. Research square (2021)
Meghna Gupta, Caleigh M Azumaya, Michelle Moritz, Sergei Pourmal, Amy Diallo, Gregory E Merz, Gwendolyn M Jang, Mehdi Bouhaddou, Andrea Fossati, Axel F Brilot, Devan Diwanji, Evelyn Hernandez, Nadia Herrera, Huong T Kratochvil, Victor L Lam, Fei Li, Yang Li, Henry C Nguyen, Carlos A Nowotny, Tristan W Owens, Jessica K Peters, Alexandrea N Rizo, Ursula Schulze-Gahmen, Amber M Smith, Iris D Young, Zanlin Yu, Daniel E Asarnow, Christian B Billesbølle, Melody G Campbell, Jen Chen, Kuei-Ho Chen, Un Seng Chio, Miles Sasha Dickinson, Loan Doan, Mingliang Jin, Sun Kyung Kim, Junrui Li, Grant J Jensen, Edmond M Linossi, Yanxin Liu, Megan Lo, Jocelyne Lopez, Kyle E Lopez, Adamo S Mancino, Frank R Moss, Michael D Paul, Komal Ishwar Pawar, Adrian Pelin, Thomas H Pospiech, Cristina Puchades, Soumya Govinda Remesh, Maliheh Safari, Kaitlin Schaefer, Ming Sun, Mariano C Tabios, Aye C Thwin, Erron W Titus, Raphael Trenker, Eric Tse, Tsz Kin Martin Tsui, Feng Wang, Kaihua Zhang, Sunny Zhang, Jianhua Zhao, Fengbo Zhou, Yuan Zhou, Lorena Zuliani-Alvarez, null null, David A Agard, Yifan Cheng, Brian K Shoichet, Natalia Jura, Tanja Kortemme, Aashish Manglik, Daniel R Southworth, Robert M Stroud, Danielle L Swaney, Nevan J Krogan, Adam Frost, Oren S Rosenberg, Kliment A Verba
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. bioRxiv : the preprint server for biology (2021)
Tina Perica, Christopher J P Mathy, Jiewei Xu, Gwendolyn Μ Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L Swaney, David G Lambright, Mark J S Kelly, Nevan J Krogan, Tanja Kortemme
Systems-level effects of allosteric perturbations to a model molecular switch. Nature 599 (7883) (2021)
Xingjie Pan, Tanja Kortemme
De novo protein fold families expand the designable ligand binding site space. PLoS computational biology 17 (11) (2021)
Julia Koehler Leman, Brian D Weitzner, Steven M Lewis, Jared Adolf-Bryfogle, Nawsad Alam, Rebecca F Alford, Melanie Aprahamian, Julien S Baker, Kyle A Barlow, Patrick Barth, Benjamin Basanta, Brian J Bender, Kristin Blacklock, Jaume Bonet, Scott E Boyken, Philip G Bradley, Chris Bystroff, Patrick Conway, Seth Cooper, Bruno E Correia, Brian Coventry, Rachel J Hagey, René M De Jong, Frank DiMaio, Lorna Dsilva, Roland L Dunbrack, Alexander S Ford, Brandon Frenz, Darwin Y Fu, Caleb Geniesse, Lukasz Goldschmidt, Ragul Gowthaman, Jeffrey J Gray, Dominik Gront, Sharon Guffy, Scott Horowitz, Po-Ssu Huang, Thomas Huber, Tim M Jacobs, Jeliazko R Jeliazkov, David K Johnson, Kalli Kappel, John Karanicolas, Hamed Khakzad, Karen R Khar, Sagar D Khare, Firas Khatib, Alisa Khramushin, Indigo C King, Robert Kleffner, Brian Koepnick, Tanja Kortemme, Georg Kuenze, Brian Kuhlman, Daisuke Kuroda, Jason W Labonte, Jason K Lai, Gideon Lapidoth, Andrew Leaver-Fay, Steffen Lindert, Thomas Linsky, Nir London, Joseph H Lubin, Sergey Lyskov, Jack Maguire, Lars Malmström, Enrique Marcos, Orly Marcu, Nicholas A Marze, Jens Meiler, Rocco Moretti, Vikram Khipple Mulligan, Santrupti Nerli, Christoffer Norn, Shane Ó'Conchúir, Noah Ollikainen, Sergey Ovchinnikov, Michael S Pacella, Xingjie Pan, Hahnbeom Park, Ryan E Pavlovicz, Manasi Pethe, Brian G Pierce, Kala Bharath Pilla, Barak Raveh, P Douglas Renfrew, Shourya S Roy Burman, Aliza Rubenstein, Marion F Sauer, Andreas Scheck, William R Schief, Ora Schueler-Furman, Yuval Sedan, Alexander M Sevy, Nikolaos G Sgourakis, Lei Shi, Justin B Siegel, Daniel-Adriano Silva, Shannon Smith, Yifan Song, Amelie Stein, Maria Szegedy, Frank D Teets, Summer B Thyme, Ray Yu-Ruei Wang, Andrew Watkins, Lior Zimmerman, Richard A Bonneau
Macromolecular modeling and design in Rosetta: recent methods and frameworks. Nature methods 17 (7) (2020)
James E Lucas, Tanja Kortemme
New computational protein design methods for de novo small molecule binding sites. PLoS computational biology 16 (10) (2020)
Anum Azam Glasgow, Yao-Ming Huang, Daniel J Mandell, Michael C Thompson, Ryan Ritterson, Amanda L Loshbaugh, Jenna Pellegrino, Cody Krivacic, Roland A Pache, Kyle A Barlow, Noah Ollikainen, Deborah Jeon, Mark J S Kelly, Brian K Shoichet, Tanja Kortemme
Computational design of a modular protein sense-response system. Science (New York, N.Y.) 366 (6468) (2020)
David E Gordon, Gwendolyn M Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M White, Matthew J O'Meara, Veronica V Rezelj, Jeffrey Z Guo, Danielle L Swaney, Tia A Tummino, Ruth Hüttenhain, Robyn M Kaake, Alicia L Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J Polacco, Hannes Braberg, Jacqueline M Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J Bennett, Merve Cakir, Michael J McGregor, Qiongyu Li, Bjoern Meyer, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, Ilsa T Kirby, James E Melnyk, John S Chorba, Kevin Lou, Shizhong A Dai, Inigo Barrio-Hernandez, Danish Memon, Claudia Hernandez-Armenta, Jiankun Lyu, Christopher J P Mathy, Tina Perica, Kala Bharath Pilla, Sai J Ganesan, Daniel J Saltzberg, Ramachandran Rakesh, Xi Liu, Sara Brin Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, José M Liboy-Lugo, Yizhu Lin, Xi-Ping Huang, YongFeng Liu, Stephanie A Wankowicz, Markus Bohn, Maliheh Safari, Fatima S Ugur, Cassandra Koh, Nastaran Sadat Savar, Quang Dinh Tran, Djoshkun Shengjuler, Sabrina J Fletcher, Michael C O'Neal, Yiming Cai, Jason C J Chang, David J Broadhurst, Saker Klippsten, Phillip P Sharp, Nicole A Wenzell, Duygu Kuzuoglu-Ozturk, Hao-Yuan Wang, Raphael Trenker, Janet M Young, Devin A Cavero, Joseph Hiatt, Theodore L Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Robert M Stroud, Alan D Frankel, Oren S Rosenberg, Kliment A Verba, David A Agard, Melanie Ott, Michael Emerman, Natalia Jura, Mark Von Zastrow, Eric Verdin, Alan Ashworth, Olivier Schwartz, Christophe D'Enfert, Shaeri Mukherjee, Matthew P Jacobson, Harmit Singh Malik, Danica G Fujimori, Trey Ideker, Charles S Craik, Stephen N Floor, Brian K Shoichet, John D Gross, Andrej Sali, Bryan L Roth, Davide Ruggero, Jack Taunton, Tanja Kortemme, Pedro Beltrao, Marco Vignuzzi, Adolfo García-Sastre, Kevan M Shokat, Brian K Shoichet, Nevan J Krogan
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature 583 (7816) (2020)
Xingjie Pan, Michael C Thompson, Sunny Zhang, Lin Liu, Brian K Shoichet, Mark J S Kelly, Tanja Kortemme
Expanding the space of protein geometries by computational design of de novo fold families. Science (New York, N.Y.) 369 (6507) (2020)
David E Gordon, Joseph Hiatt, Mehdi Bouhaddou, Veronica V Rezelj, Svenja Ulferts, Hannes Braberg, Alexander S Jureka, Kirsten Obernier, Jeffrey Z Guo, Jyoti Batra, Robyn M Kaake, Andrew R Weckstein, Tristan W Owens, Meghna Gupta, Sergei Pourmal, Erron W Titus, Merve Cakir, Margaret Soucheray, Michael J McGregor, Zeynep Cakir, Gwendolyn M Jang, Matthew J O'Meara, Tia A Tummino, Ziyang Zhang, Helene Foussard, Ajda Rojc, Yuan Zhou, Dmitry Kuchenov, Ruth Hüttenhain, Jiewei Xu, Manon Eckhardt, Danielle L Swaney, Jacqueline M Fabius, Manisha Ummadi, Beril Tutuncuoglu, Ujjwal Rathore, Maya Modak, Paige Haas, Kelsey M Haas, Zun Zar Chi Naing, Ernst H Pulido, Ying Shi, Inigo Barrio-Hernandez, Danish Memon, Eirini Petsalaki, Alistair S Dunham, Miguel Correa Marrero, David Francis Burke, Cassandra Koh, Thomas Vallet, Jesus A Silvas, Caleigh M Azumaya, Christian B Billesbølle, Axel F Brilot, Melody G Campbell, Amy Diallo, Miles Sasha Dickinson, Devan Diwanji, Nadia Herrera, Nicholas Hoppe, Huong T Kratochvil, Yanxin Liu, Gregory E Merz, Michelle Moritz, Henry C Nguyen, Carlos A Nowotny, Cristina Puchades, Alexandrea N Rizo, Ursula Schulze-Gahmen, Amber M Smith, Ming Sun, Iris D Young, Jianhua Zhao, Daniel Asarnow, Justin T Biel, Alisa Bowen, Julian R Braxton, Jen Chen, Cynthia M Chio, Un Seng Chio, Ishan Deshpande, Loan Doan, Bryan Faust, Sebastian Flores, Mingliang Jin, Sun Kyung Kim, Victor L Lam, Fei Li, Junrui Li, Grant J Jensen, Yang Li, Xi Liu, Megan Lo, Kyle E Lopez, Arthur A Melo, Frank R Moss, Phuong Nguyen, Joana Paulino, Komal Ishwar Pawar, Jessica K Peters, Thomas H Pospiech, Maliheh Safari, Smriti Sangwan, Kaitlin Schaefer, Paul V Thomas, Aye C Thwin, Raphael Trenker, Eric Tse, Tsz Kin Martin Tsui, Feng Wang, Natalie Whitis, Zanlin Yu, Kaihua Zhang, Sunny Zhang, Fengbo Zhou, Daniel J Saltzberg, null null, Anthony J Hodder, Amber S Shun-Shion, Daniel M Williams, Kris M White, Romel Rosales, Thomas Kehrer, Lisa Miorin, Elena Moreno, Arvind H Patel, Suzannah J Rihn, Mir Mubashir Khalid, Albert Vallejo-Gracia, Parinaz Fozouni, Camille R Simoneau, Theodore L Roth, David Wu, Mohd Anisul Karim, Maya Ghoussaini, Ian Dunham, Francesco Berardi, Sebastian Weigang, Maxime Chazal, Jisoo Park, James P Logue, Marisa E McGrath, Stuart M Weston, Robert E Haupt, C James Hastie, Matthew Elliott, Fiona Brown, Kerry A Burness, Elaine Reid, Mark Dorward, Clare Johnson, Stuart G Wilkinson, Anna Geyer, Daniel M Giesel, Carla Baillie, Samantha Raggett, Hannah Leech, Rachel Toth, Nicola Goodman, Kathleen C Keough, Abigail L Lind, null null, Reyna J Klesh, Kafi R Hemphill, Jared Carlson-Stevermer, Jennifer Oki, Kevin Holden, Travis Maures, Katherine S Pollard, Andrej Sali, David A Agard, Yifan Cheng, Brian K Shoichet, Adam Frost, Natalia Jura, Tanja Kortemme, Aashish Manglik, Daniel R Southworth, Robert M Stroud, Dario R Alessi, Paul Davies, Matthew B Friemann, Trey Ideker, Carmen Abate, Nolwenn Jouvenet, Georg Kochs, Brian K Shoichet, Melanie M Ott, Massimo Palmarini, Kevan M Shokat, Adolfo García-Sastre, Jeremy A Rassen, Robert Grosse, Oren S Rosenberg, Kliment A Verba, Christopher F Basler, Marco Vignuzzi, Andrew A Peden, Pedro Beltrao, Nevan J Krogan
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science (New York, N.Y.) 370 (6521) (2020)
Samuel Thompson, Yang Zhang, Christine Ingle, Kimberly A Reynolds, Tanja Kortemme
Altered expression of a quality control protease in E. coli reshapes the in vivo mutational landscape of a model enzyme. eLife 9 (2020)
Amanda L Loshbaugh, Tanja Kortemme
Comparison of Rosetta flexible-backbone computational protein design methods on binding interactions. Proteins 88 (1) (2019)
Kale Kundert, James E Lucas, Kyle E Watters, Christof Fellmann, Andrew H Ng, Benjamin M Heineike, Christina M Fitzsimmons, Benjamin L Oakes, Jiuxin Qu, Neha Prasad, Oren S Rosenberg, David F Savage, Hana El-Samad, Jennifer A Doudna, Tanja Kortemme
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs. Nature communications 10 (1) (2019)
Kyle A Barlow, Shane Ó Conchúir, Samuel Thompson, Pooja Suresh, James E Lucas, Markus Heinonen, Tanja Kortemme
Flex ddG: Rosetta Ensemble-Based Estimation of Changes in Protein-Protein Binding Affinity upon Mutation. The journal of physical chemistry. B 122 (21) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Tanja Kortemme