Christina Curtis

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 34

Top Topics

Squamous Cell Carcinoma

Estrogen Receptor

Positive Breast Cancer

Top Venues

Nature communications

Nature genetics

Nature medicine

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Kathleen E Houlahan, Aziz Khan, Noah F Greenwald, Cristina Sotomayor Vivas, Robert B West, R Michael Angelo, Christina Curtis
Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity. Science (New York, N.Y.) 384 (6699) (2024)
Angelo Fortunato, Diego Mallo, Luis Cisneros, Lorraine M King, Aziz Khan, Christina Curtis, Marc D Ryser, Joseph Y Lo, Allison Hall, Jeffrey R Marks, E Shelley Hwang, Carlo C Maley
Evolutionary Measures Show that Recurrence of DCIS is Distinct from Progression to Breast Cancer. medRxiv : the preprint server for health sciences (2024)
Kathleen E Houlahan, Aziz Khan, Noah F Greenwald, Cristina Sotomayor Vivas, Robert B West, R Michael Angelo, Christina Curtis
Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity. Science (New York, N.Y.) 384 (6699) (2024)
Laksshman Sundaram, Arvind Kumar, Matthew Zatzman, Adriana Salcedo, Neal G Ravindra, Shadi Shams, Brian H Louie, S Tansu Bagdatli, Matthew A Myers, Shahab Sarmashghi, Hyo Young Choi, Won-Young Choi, Kathryn E Yost, Yanding Zhao, Jeffrey M Granja, Toshinori Hinoue, David Neil Hayes, Andrew D Cherniak, Ina Felau, Hani Choudhry, Jean Claude Zenklusen, Kyle Kai-How Farh, Andrew W McPherson, Christina Curtis, Peter W Laird, null null, M Ryan Corces, Howard Y Chang, William J Greenleaf, John A Demchok, Liming Yang, Roy Tarnuzzer, Samantha J Caesar-Johnson, Zhining Wang, Ashley S Doane, Ekta Khurana, Mauro A A Castro, Alexander J Lazar, Bradley M Broom, John N Weinstein, Rehan Akbani, Shwetha V Kumar, Benjamin J Raphael, Christopher K Wong, Joshua M Stuart, Rojin Safavi, Christopher C Benz, Benjamin K Johnson, Cindy Kyi, Hui Shen
Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers. Science (New York, N.Y.) 385 (6713) (2024)
Kathleen E Houlahan, Aziz Khan, Noah F Greenwald, Cristina Sotomayor Vivas, Robert B West, R Michael Angelo, Christina Curtis
Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity. Science (New York, N.Y.) 384 (6699) (2024)
Angelo Fortunato, Diego Mallo, Luis Cisneros, Lorraine M King, Aziz Khan, Christina Curtis, Marc D Ryser, Joseph Y Lo, Allison Hall, Jeffrey R Marks, E Shelley Hwang, Carlo C Maley
Evolutionary Measures Show that Recurrence of DCIS is Distinct from Progression to Breast Cancer. medRxiv : the preprint server for health sciences (2024)
Kasper Karlsson, Moritz Jakob Przybilla, Eran Kotler, Aziz Khan, Hang Xu, Kremena Karagyozova, Alexandra Sockell, Wing H Wong, Katherine Liu, Amanda Mah, Yuan-Hung Lo, Bingxin Lu, Kathleen E Houlahan, Zhicheng Ma, Carlos J Suarez, Christopher P Barnes, Calvin J Kuo, Christina Curtis
Deterministic evolution and stringent selection during preneoplasia. Nature (2023)
Courtney R Schott, Amanda L Koehne, Leanne C Sayles, Elizabeth P Young, Cuyler Luck, Katharine Yu, Alex G Lee, Marcus R Breese, Stanley G Leung, Hang Xu, Avanthi Tayi Shah, Heng-Yi Liu, Aviv Spillinger, Inge H Behroozfard, Kieren D Marini, Phuong T Dinh, Mar A V Pons Ventura, Emma N Vanderboon, Florette K Hazard, Soo-Jin Cho, Raffi S Avedian, David G Mohler, Melissa Zimel, Rosanna Wustrack, Christina Curtis, Marina Sirota, E Alejandro Sweet-Cordero
Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities. bioRxiv : the preprint server for biology (2023)
Albert M Li, Bo He, Dimitris Karagiannis, Yang Li, Haowen Jiang, Preethi Srinivasan, Yaniel Ramirez, Meng-Ning Zhou, Christina Curtis, Joshua J Gruber, Chao Lu, Erinn B Rankin, Jiangbin Ye
Serine starvation silences estrogen receptor signaling through histone hypoacetylation. Proceedings of the National Academy of Sciences of the United States of America 120 (38) (2023)
Courtney R Schott, Amanda L Koehne, Leanne C Sayles, Elizabeth P Young, Cuyler Luck, Katherine Yu, Alex G Lee, Marcus R Breese, Stanley G Leung, Hang Xu, Avanthi Tayi Shah, Heng-Yi Liu, Aviv Spillinger, Inge H Behroozfard, Kieren D Marini, Phuong T Dinh, María V Pons Ventura, Emma N Vanderboon, Florette K Hazard, Soo-Jin Cho, Raffi S Avedian, David G Mohler, Melissa N Zimel, Rosanna L Wustrack, Christina Curtis, Marina Sirota, E Alejandro Sweet-Cordero
Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Kun Wang, Liangzhen Hou, Xin Wang, Xiangwei Zhai, Zhaolian Lu, Zhike Zi, Weiwei Zhai, XiongLei He, Christina Curtis, Da Zhou, Zheng Hu
PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes. Nature biotechnology (2023)
Susanne Tilk, Svyatoslav Tkachenko, Christina Curtis, Dmitri A Petrov, Christopher D McFarland
Most cancers carry a substantial deleterious load due to Hill-Robertson interference. eLife 11 (2022)
Brittany M Flowers, Hang Xu, Abigail S Mulligan, Kathryn J Hanson, José A Seoane, Hannes Vogel, Christina Curtis, Laura D Wood, Laura D Attardi
Cell of Origin Influences Pancreatic Cancer Subtype. Cancer discovery 11 (3) (2022)
Jennifer L Caswell-Jin, Christina Curtis
Androgen receptor agonists as breast cancer therapeutics. Nature medicine 27 (2) (2021)
Katherine L McNamara, Jennifer L Caswell-Jin, Rohan P Joshi, Zhicheng Ma, Eran Kotler, Gregory R Bean, Michelle Kriner, Zoey Zhou, Margaret L Hoang, Joseph Beechem, Jason Zoeller, Michael F Press, Dennis J Slamon, Sara A Hurvitz, Christina Curtis
Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response. Nature cancer 2 (4) (2021)
Emily Golden, Rabab Rashwan, Eleanor A Woodward, Agustin Sgro, Edina Wang, Anabel Sorolla, Charlene Waryah, Wan Jun Tie, Elisabet Cuyàs, Magdalena Ratajska, Iwona Kardaś, Kozłowski Piotr, Elizabeth K M Johnstone, Heng B See, Ciara Duffy, Jeremy Parry, Kim A Lagerborg, Piotr Czapiewski, Javier A Menendez, Adam Gorczyński, Bartosz Wasag, Kevin D G Pfleger, Christina Curtis, Bum-Kyu Lee, Jonghwan Kim, Joseph Cursons, Nathan J Pavlos, Wojciech Biernat, Mohit Jain, Andrew J Woo, Andrew Redfern, Pilar Blancafort
The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer. Nature communications 12 (1) (2021)
Andrea C Chaikovsky, Chuan Li, Edwin E Jeng, Samuel Loebell, Myung Chang Lee, Christopher W Murray, Ran Cheng, Janos Demeter, Danielle L Swaney, Si-Han Chen, Billy W Newton, Jeffrey R Johnson, Alexandros P Drainas, Yan Ting Shue, José A Seoane, Preethi Srinivasan, Andy He, Akihiro Yoshida, Susan Q Hipkins, Edel McCrea, Carson D Poltorack, Nevan J Krogan, J Alan Diehl, Christina Kong, Peter K Jackson, Christina Curtis, Dmitri A Petrov, Michael C Bassik, Monte M Winslow, Julien Sage
The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D. Nature 592 (7856) (2021)
Iris Nederlof, Hugo Mark Horlings, Christina Curtis, Marleen Kok
A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer. Cancers 13 (2) (2021)
Yuan-Hung Lo, Kevin S Kolahi, Yuhong Du, Chiung-Ying Chang, Andrey Krokhotin, Bindu Nair, Walter D Sobba, Kasper Karlsson, Sunny J Jones, Teri A Longacre, Amanda T Mah, Bahar Tercan, Alexandra Sockell, Hang Xu, José A Seoane, Jin Chen, Ilya Shmulevich, Jonathan S Weissman, Christina Curtis, Andrea Califano, Haian Fu, Gerald R Crabtree, Calvin J Kuo
A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation. Cancer discovery 11 (6) (2021)
Zheng Hu, Zan Li, Zhicheng Ma, Christina Curtis
Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases. Nature genetics 52 (7) (2020)
Sara A Hurvitz, Jennifer L Caswell-Jin, Katherine L McNamara, Jason J Zoeller, Gregory R Bean, Robert Dichmann, Alejandra Perez, Ravindranath Patel, Lee Zehngebot, Heather Allen, Linda Bosserman, Brian DiCarlo, April Kennedy, Armando Giuliano, Carmen Calfa, David Molthrop, Aruna Mani, Hsiao-Wang Chen, Judy Dering, Brad Adams, Eran Kotler, Michael F Press, Joan S Brugge, Christina Curtis, Dennis J Slamon
Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07). Nature communications 11 (1) (2020)
Zheng Hu, Christina Curtis
Looking backward in time to define the chronology of metastasis. Nature communications 11 (1) (2020)
Yiren Xiao, Kaushik N Thakkar, Hongjuan Zhao, James Broughton, Yang Li, José A Seoane, Anh N Diep, Thomas J Metzner, Rie von Eyben, David L Dill, James D Brooks, Christina Curtis, John T Leppert, Jiangbin Ye, Donna M Peehl, Amato J Giaccia, Subarna Sinha, Erinn B Rankin
The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America 117 (35) (2020)
Nastaran Zahir, Ruping Sun, Daniel Gallahan, Robert A Gatenby, Christina Curtis
Characterizing the ecological and evolutionary dynamics of cancer. Nature genetics 52 (8) (2020)
Kyuho Han, Sarah E Pierce, Amy Li, Kaitlyn Spees, Grace R Anderson, José A Seoane, Yuan-Hung Lo, Michael Dubreuil, Micah Olivas, Roarke A Kamber, Michael Wainberg, Kaja Kostyrko, Marcus R Kelly, Maryam Yousefi, Scott W Simpkins, David Yao, Keonil Lee, Calvin J Kuo, Peter K Jackson, E Alejandro Sweet-Cordero, Anshul Kundaje, Andrew J Gentles, Christina Curtis, Monte M Winslow, Michael C Bassik
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities. Nature 580 (7801) (2020)
José A Seoane, Jacob G Kirkland, Jennifer L Caswell-Jin, Gerald R Crabtree, Christina Curtis
Chromatin regulators mediate anthracycline sensitivity in breast cancer. Nature medicine 25 (11) (2019)
Jennifer L Caswell-Jin, Katherine L McNamara, Johannes G Reiter, Ruping Sun, Zheng Hu, Zhicheng Ma, Jie Ding, Carlos J Suarez, Susanne Tilk, Akshara Raghavendra, Victoria Forte, Suet-Feung Chin, Helen Bardwell, Elena Provenzano, Carlos Caldas, Julie E Lang, Robert West, Debasish Tripathy, Michael F Press, Christina Curtis
Publisher Correction: Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy. Nature communications 10 (1) (2019)
Christopher Probert, Christina Curtis
A role for chromatin regulatory dynamics in breast cancer evolution. Nature medicine 24 (9) (2019)
Kathryn E Yost, Ansuman T Satpathy, Daniel K Wells, Yanyan Qi, Chunlin Wang, Robin Kageyama, Katherine L McNamara, Jeffrey M Granja, Kavita Y Sarin, Ryanne A Brown, Rohit K Gupta, Christina Curtis, Samantha L Bucktrout, Mark M Davis, Anne Lynn S Chang, Howard Y Chang
Clonal replacement of tumor-specific T cells following PD-1 blockade. Nature medicine 25 (8) (2019)
Jennifer L Caswell-Jin, Katherine L McNamara, Johannes G Reiter, Ruping Sun, Zheng Hu, Zhicheng Ma, Jie Ding, Carlos J Suarez, Susanne Tilk, Akshara Raghavendra, Victoria Forte, Suet-Feung Chin, Helen Bardwell, Elena Provenzano, Carlos Caldas, Julie E Lang, Robert West, Debasish Tripathy, Michael F Press, Christina Curtis
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy. Nature communications 10 (1) (2019)
Zheng Hu, Jie Ding, Zhicheng Ma, Ruping Sun, José A Seoane, J Scott Shaffer, Carlos J Suarez, Anna S Berghoff, Chiara Cremolini, Alfredo Falcone, Fotios Loupakis, Peter Birner, Matthias Preusser, Heinz-Josef Lenz, Christina Curtis
Quantitative evidence for early metastatic seeding in colorectal cancer. Nature genetics 51 (7) (2019)
Ami S Bhatt, Christina Curtis
AGBT meeting report. Genome biology 19 (1) (2018)
Zoë N Rogers, Christopher D McFarland, Ian P Winters, Jose A Seoane, Jennifer J Brady, Stephanie Yoon, Christina Curtis, Dmitri A Petrov, Monte M Winslow
Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice. Nature genetics 50 (4) (2018)
Marc J Williams, Benjamin Werner, Timon Heide, Christina Curtis, Christopher P Barnes, Andrea Sottoriva, Trevor A Graham
Quantification of subclonal selection in cancer from bulk sequencing data. Nature genetics 50 (6) (2018)