Morgan E Diolati (Morgan Diolaiti, Morgan E Diolaiti)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 25

Top Topics

Molecular Dynamics Simulations

Respiratory Syndrome Coronavirus

Capillary Electrophoresis

Top Venues

Science (New York, N.Y.)

Proceedings of the National Academy of Sciences of the United States of America

bioRxiv : the preprint server for biology

Molecular cancer therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

Daphne F Chen, Leah Tang Roe, Yuping Li, Adair L Borges, Jenny Y Zhang, Palak Babbar, Sourobh Maji, Maisie G V Stevens, Galen J Correy, Morgan E Diolati, Dominique H Smith, Alan Ashworth, Robert M Stroud, Mark J S Kelly, Joseph Bondy-Denomy, Brian K Shoichet
AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid. bioRxiv : the preprint server for biology (2024)
Rahul K Suryawanshi, Priyadarshini Jaishankar, Galen J Correy, Moira M Rachman, Patrick C O'Leary, Taha Y Taha, Francisco J Zapatero-Belinchón, Maria McCavitt-Malvido, Yagmur Umay Doruk, Maisie G V Stevens, Morgan E Diolati, Manasi P Jogalekar, Alicia L Richards, Mauricio Montano, Julia Rosecrans, Michael A Matthay, Takaya Togo, Ryan L Gonciarz, Saumya Gopalkrishnan, R Jeffrey Neitz, Nevan J Krogan, Danielle L Swaney, Brian K Shoichet, Melanie M Ott, Adam R Renslo, Alan Ashworth, Brian K Shoichet
The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2. bioRxiv : the preprint server for biology (2024)
Lei Lu, Xuxu Gou, Sophia K Tan, Samuel I Mann, Hyunjun Yang, Xiaofang Zhong, Dimitrios Gazgalis, Jesús Valdiviezo, Hyunil Jo, Yibing Wu, Morgan E Diolati, Alan Ashworth, Nicholas F Polizzi, William F DeGrado
De novo design of drug-binding proteins with predictable binding energy and specificity. Science (New York, N.Y.) 384 (6691) (2024)
Lei Lu, Xuxu Gou, Sophia K Tan, Samuel I Mann, Hyunjun Yang, Xiaofang Zhong, Dimitrios Gazgalis, Jesús Valdiviezo, Hyunil Jo, Yibing Wu, Morgan E Diolati, Alan Ashworth, Nicholas F Polizzi, William F DeGrado
De novo design of drug-binding proteins with predictable binding energy and specificity. Science (New York, N.Y.) 384 (6691) (2024)
Lei Lu, Xuxu Gou, Sophia K Tan, Samuel I Mann, Hyunjun Yang, Xiaofang Zhong, Dimitrios Gazgalis, Jesús Valdiviezo, Hyunil Jo, Yibing Wu, Morgan E Diolati, Alan Ashworth, Nicholas F Polizzi, William F DeGrado
De novo design of drug-binding proteins with predictable binding energy and specificity. Science (New York, N.Y.) 384 (6691) (2024)
Lei Lu, Xuxu Gou, Sophia K Tan, Samuel I Mann, Hyunjun Yang, Xiaofang Zhong, Dimitrios Gazgalis, Jesús Valdiviezo, Hyunil Jo, Yibing Wu, Morgan E Diolati, Alan Ashworth, Nicholas F Polizzi, William F DeGrado
De novo design of drug-binding proteins with predictable binding energy and specificity. Science (New York, N.Y.) 384 (6691) (2024)
Rahul K Suryawanshi, Priyadarshini Jaishankar, Galen J Correy, Moira M Rachman, Patrick C O'Leary, Taha Y Taha, Francisco J Zapatero-Belinchón, Maria McCavitt-Malvido, Yagmur Umay Doruk, Maisie G V Stevens, Morgan E Diolati, Manasi P Jogalekar, Alicia L Richards, Mauricio Montano, Julia Rosecrans, Michael A Matthay, Takaya Togo, Ryan L Gonciarz, Saumya Gopalkrishnan, R Jeffrey Neitz, Nevan J Krogan, Danielle L Swaney, Brian K Shoichet, Melanie M Ott, Adam R Renslo, Alan Ashworth, Brian K Shoichet
The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2. bioRxiv : the preprint server for biology (2024)
Lei Lu, Xuxu Gou, Sophia K Tan, Samuel I Mann, Hyunjun Yang, Xiaofang Zhong, Dimitrios Gazgalis, Jesús Valdiviezo, Hyunil Jo, Yibing Wu, Morgan E Diolati, Alan Ashworth, Nicholas F Polizzi, William F DeGrado
De novo design of drug-binding proteins with predictable binding energy and specificity. Science (New York, N.Y.) 384 (6691) (2024)
Lei Lu, Xuxu Gou, Sophia K Tan, Samuel I Mann, Hyunjun Yang, Xiaofang Zhong, Dimitrios Gazgalis, Jesús Valdiviezo, Hyunil Jo, Yibing Wu, Morgan E Diolati, Alan Ashworth, Nicholas F Polizzi, William F DeGrado
De novo design of drug-binding proteins with predictable binding energy and specificity. Science (New York, N.Y.) 384 (6691) (2024)
Lei Lu, Xuxu Gou, Sophia K Tan, Samuel I Mann, Hyunjun Yang, Xiaofang Zhong, Dimitrios Gazgalis, Jesús Valdiviezo, Hyunil Jo, Yibing Wu, Morgan E Diolati, Alan Ashworth, Nicholas F Polizzi, William F DeGrado
De novo design of drug-binding proteins with predictable binding energy and specificity. Science (New York, N.Y.) 384 (6691) (2024)
Lei Lu, Xuxu Gou, Sophia K Tan, Samuel I Mann, Hyunjun Yang, Xiaofang Zhong, Dimitrios Gazgalis, Jesús Valdiviezo, Hyunil Jo, Yibing Wu, Morgan E Diolati, Alan Ashworth, Nicholas F Polizzi, William F DeGrado
De novo design of drug-binding proteins with predictable binding energy and specificity. Science (New York, N.Y.) 384 (6691) (2024)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Patrick C O'Leary, Hua-Dong Chen, Yagmur Umay Doruk, Tess Williamson, Benjamin J Polacco, Andrew S McNeal, Tanushree Shenoy, Nupura Kale, Julia Carnevale, Erica Stevenson, David A Quigley, Jonathan Chou, Felix Y Feng, Danielle L Swaney, Nevan J Krogan, Minkyu Kim, Morgan E Diolati, Alan Ashworth
Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2. Cancer research 82 (21) (2022)
Anish Thomas, Shaun D Fontaine, Morgan E Diolati, Parth Desai, Rajesh Kumar, Nobuyuki Takahashi, Linda Sciuto, Samantha Nichols, Alan Ashworth, Felix Y Feng, Gary W Ashley, Minh Nguyen, Yves Pommier, Daniel V Santi
PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM-Deficient Tumors and Potent Synergy With PARP Inhibitors. Molecular cancer therapeutics 21 (11) (2022)
Julia Carnevale, Eric Shifrut, Nupura Kale, William A Nyberg, Franziska Blaeschke, Yan Yi Chen, Zhongmei Li, Sagar P Bapat, Morgan E Diolati, Patrick C O'Leary, Shane Vedova, Julia A Belk, Bence Daniel, Theodore L Roth, Stefanie Bachl, Alejandro Allo Anido, Brooke Prinzing, Jorge Ibañez-Vega, Shannon Lange, Dalia Haydar, Marie Luetke-Eversloh, Maelys Born-Bony, Bindu Hegde, Scott C Kogan, Tobias Feuchtinger, Hideho Okada, Ansuman T Satpathy, Kevin Shannon, Stephen Gottschalk, Justin Eyquem, Giedre Krenciute, Alan Ashworth, Alexander Marson
RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature 609 (7925) (2022)
Hua-Dong Chen, Morgan E Diolati, Patrick C O'Leary, Ajda Rojc, Nevan J Krogan, Minkyu Kim, Alan Ashworth
A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor. Molecular cancer therapeutics 21 (7) (2022)
Stefan Gahbauer, Galen J Correy, Marion Schuller, Matteo P Ferla, Yagmur Umay Doruk, Moira M Rachman, Taiasean Wu, Morgan E Diolati, Siyi Wang, R Jeffrey Neitz, Daren Fearon, Dmytro S Radchenko, Yurii S Moroz, John J Irwin, Adam R Renslo, Jenny C Taylor, Jason E Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K Shoichet, Brian K Shoichet
Structure-based inhibitor optimization for the Nsp3 Macrodomain of SARS-CoV-2. bioRxiv : the preprint server for biology (2022)
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael J McGregor, Patrick C O'Leary, Denise Wolf, Erica Stevenson, Tzeh Keong Foo, Dominique C Mitchell, Kari A Herrington, Denise P Muñoz, Beril Tutuncuoglu, Kuei-Ho Chen, Fan Zheng, Jason F Kreisberg, Morgan E Diolati, John D Gordan, Jean-Philippe Coppé, Danielle L Swaney, Bing Xia, Laura van 't Veer, Alan Ashworth, Trey Ideker, Nevan J Krogan
A protein interaction landscape of breast cancer. Science (New York, N.Y.) 374 (6563) (2021)