Oliver Werz

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 87

Top Topics

Cell Cycle Arrest

Inflammatory Response

Atopic Dermatitis

Top Venues

International journal of molecular sciences

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Pharmaceuticals (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Bodo Speckmann, Tanja Wagner, Paul M Jordan, Oliver Werz, Manfred Wilhelm, Heike Tom Dieck, Christiane Schön
Synbiotic Bacillus megaterium DSM 32963 and n-3 PUFA Salt Composition Elevates Pro-Resolving Lipid Mediator Levels in Healthy Subjects: A Randomized Controlled Study. Nutrients 16 (9) (2024)
Dávid Roman, Philippe Meisinger, Richard Guillonneau, Chia-Chi Peng, Lukas K Peltner, Paul M Jordan, Veit Haensch, Sebastian Götze, Oliver Werz, Christian Hertweck, Yin Chen, Christine Beemelmanns
Structure Revision of a Widespread Marine Sulfonolipid Class Based on Isolation and Total Synthesis. Angewandte Chemie (International ed. in English) 63 (23) (2024)
Jana Ismail, Lea C Klepsch, Philipp Dahlke, Ekaterina Tsarenko, Antje Vollrath, David Pretzel, Paul M Jordan, Kourosh Rezaei, Justyna A Czaplewska, Steffi Stumpf, Baerbel Beringer-Siemers, Ivo Nischang, Stephanie Hoeppener, Oliver Werz, Ulrich S Schubert
PEG-Lipid-PLGA Hybrid Particles for Targeted Delivery of Anti-Inflammatory Drugs. Pharmaceutics 16 (2) (2024)
Dávid Roman, Philippe Meisinger, Richard Guillonneau, Chia-Chi Peng, Lukas K Peltner, Paul M Jordan, Veit Haensch, Sebastian Götze, Oliver Werz, Christian Hertweck, Yin Chen, Christine Beemelmanns
Structure Revision of a Widespread Marine Sulfonolipid Class Based on Isolation and Total Synthesis. Angewandte Chemie (International ed. in English) (2024)
Bodo Speckmann, Tanja Wagner, Paul M Jordan, Oliver Werz, Manfred Wilhelm, Heike Tom Dieck, Christiane Schön
Synbiotic Bacillus megaterium DSM 32963 and n-3 PUFA Salt Composition Elevates Pro-Resolving Lipid Mediator Levels in Healthy Subjects: A Randomized Controlled Study. Nutrients 16 (9) (2024)
Paul Zahel, Vera Bruggink, Juliana Hülsmann, Frank Steiniger, Robert Klaus Hofstetter, Thorsten Heinzel, Uwe Beekmann, Oliver Werz, Dana Kralisch
Exploring Microemulsion Systems for the Incorporation of Glucocorticoids into Bacterial Cellulose: A Novel Approach for Anti-Inflammatory Wound Dressings. Pharmaceutics 16 (4) (2024)
Jana Ismail, Lea C Klepsch, Philipp Dahlke, Ekaterina Tsarenko, Antje Vollrath, David Pretzel, Paul M Jordan, Kourosh Rezaei, Justyna A Czaplewska, Steffi Stumpf, Baerbel Beringer-Siemers, Ivo Nischang, Stephanie Hoeppener, Oliver Werz, Ulrich S Schubert
PEG-Lipid-PLGA Hybrid Particles for Targeted Delivery of Anti-Inflammatory Drugs. Pharmaceutics 16 (2) (2024)
Samim Sharifi, Prerana Chaudhari, Asya Martirosyan, Alexander Otto Eberhardt, Finja Witt, André Gollowitzer, Lisa Lange, Yvonne Woitzat, Eberechukwu Maryann Okoli, Huahui Li, Norman Rahnis, Joanna Kirkpatrick, Oliver Werz, Alessandro Ori, Andreas Koeberle, Holger Bierhoff, Maria A Ermolaeva
Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans. Nature communications 15 (1) (2024)
Oliver Werz, Hans Stettler, Christoph Theurer, Jens Seibel
The 125th Anniversary of Aspirin-The Story Continues. Pharmaceuticals (Basel, Switzerland) 17 (4) (2024)
Samim Sharifi, Prerana Chaudhari, Asya Martirosyan, Alexander Otto Eberhardt, Finja Witt, André Gollowitzer, Lisa Lange, Yvonne Woitzat, Eberechukwu Maryann Okoli, Huahui Li, Norman Rahnis, Joanna Kirkpatrick, Oliver Werz, Alessandro Ori, Andreas Koeberle, Holger Bierhoff, Maria A Ermolaeva
Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans. Nature communications 15 (1) (2024)
Oliver Werz, Hans Stettler, Christoph Theurer, Jens Seibel
The 125th Anniversary of Aspirin-The Story Continues. Pharmaceuticals (Basel, Switzerland) 17 (4) (2024)
Samim Sharifi, Prerana Chaudhari, Asya Martirosyan, Alexander Otto Eberhardt, Finja Witt, André Gollowitzer, Lisa Lange, Yvonne Woitzat, Eberechukwu Maryann Okoli, Huahui Li, Norman Rahnis, Joanna Kirkpatrick, Oliver Werz, Alessandro Ori, Andreas Koeberle, Holger Bierhoff, Maria A Ermolaeva
Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans. Nature communications 15 (1) (2024)
Dávid Roman, Philippe Meisinger, Richard Guillonneau, Chia-Chi Peng, Lukas K Peltner, Paul M Jordan, Veit Haensch, Sebastian Götze, Oliver Werz, Christian Hertweck, Yin Chen, Christine Beemelmanns
Structure Revision of a Widespread Marine Sulfonolipid Class Based on Isolation and Total Synthesis. Angewandte Chemie (International ed. in English) 63 (23) (2024)
Bodo Speckmann, Tanja Wagner, Paul M Jordan, Oliver Werz, Manfred Wilhelm, Heike Tom Dieck, Christiane Schön
Synbiotic Bacillus megaterium DSM 32963 and n-3 PUFA Salt Composition Elevates Pro-Resolving Lipid Mediator Levels in Healthy Subjects: A Randomized Controlled Study. Nutrients 16 (9) (2024)
Kerstin Günther, Vivien Nischang, Zoltan Cseresnyés, Thomas Krüger, Dalia Sheta, Zahraa Abboud, Thorsten Heinekamp, Markus Werner, Olaf Kniemeyer, Andreas Beilhack, Marc Thilo Figge, Axel A Brakhage, Oliver Werz, Paul M Jordan
Aspergillus fumigatus-derived gliotoxin impacts innate immune cell activation through modulating lipid mediator production in macrophages. Immunology (2024)
Paul Zahel, Vera Bruggink, Juliana Hülsmann, Frank Steiniger, Robert Klaus Hofstetter, Thorsten Heinzel, Uwe Beekmann, Oliver Werz, Dana Kralisch
Exploring Microemulsion Systems for the Incorporation of Glucocorticoids into Bacterial Cellulose: A Novel Approach for Anti-Inflammatory Wound Dressings. Pharmaceutics 16 (4) (2024)
Max Naumann, Natalie Arend, Rustam R Guliev, Christian Kretzer, Ignacio Rubio, Oliver Werz, Ute Neugebauer
Label-Free Characterization of Macrophage Polarization Using Raman Spectroscopy. International journal of molecular sciences 24 (1) (2023)
Patrick Schädel, Mareike Wichmann-Costaganna, Anna Czapka, Nadja Gebert, Alessandro Ori, Oliver Werz
Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice. Nutrients 15 (16) (2023)
Sijia Liao, André Gollowitzer, Lisa Börmel, Charlotte Maier, Luisa Gottschalk, Oliver Werz, Maria Wallert, Andreas Koeberle, Stefan Lorkowski
α-Tocopherol-13'-Carboxychromanol Induces Cell Cycle Arrest and Cell Death by Inhibiting the SREBP1-SCD1 Axis and Causing Imbalance in Lipid Desaturation. International journal of molecular sciences 24 (11) (2023)
Sigitas Mikutis, Stefanie Lawrinowitz, Christian Kretzer, Lavinia Dunsmore, Laurynas Sketeris, Tiago Rodrigues, Oliver Werz, Gonçalo J L Bernardes
Machine Learning Uncovers Natural Product Modulators of the 5-Lipoxygenase Pathway and Facilitates the Elucidation of Their Biological Mechanisms. ACS chemical biology (2023)
Abdurrahman Olgac, İrfan Çapan, Philipp Dahlke, Paul M Jordan, Oliver Werz, Erden Banoglu
Substituted 1,2,4-Triazoles as Novel and Selective Inhibitors of Leukotriene Biosynthesis Targeting 5-Lipoxygenase-Activating Protein. ACS omega 8 (34) (2023)
Tarvi Teder, Stefanie König, Rajkumar Singh, Bengt Samuelsson, Oliver Werz, Ulrike Garscha, Jesper Z Haeggström
Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase. International journal of molecular sciences 24 (8) (2023)
Sigitas Mikutis, Stefanie Lawrinowitz, Christian Kretzer, Lavinia Dunsmore, Laurynas Sketeris, Tiago Rodrigues, Oliver Werz, Gonçalo J L Bernardes
Machine Learning Uncovers Natural Product Modulators of the 5-Lipoxygenase Pathway and Facilitates the Elucidation of Their Biological Mechanisms. ACS chemical biology 19 (1) (2023)
Tuğçe Gür Maz, Beyzanur Koc, Paul M Jordan, Kubra Ibis, Burcu Çalışkan, Oliver Werz, Erden Banoglu
Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors. ACS omega 8 (2) (2023)
Sigitas Mikutis, Stefanie Lawrinowitz, Christian Kretzer, Lavinia Dunsmore, Laurynas Sketeris, Tiago Rodrigues, Oliver Werz, Gonçalo J L Bernardes
Machine Learning Uncovers Natural Product Modulators of the 5-Lipoxygenase Pathway and Facilitates the Elucidation of Their Biological Mechanisms. ACS chemical biology 19 (1) (2023)
Johann Röhrl, Maria-Riera Piqué-Borràs, Manuela Jaklin, Markus Werner, Oliver Werz, Heinke Josef, Hubert Hölz, Aldo Ammendola, Gerald Künstle
Anti-Inflammatory Activities of Arnica montana Planta Tota versus Flower Extracts: Analytical, In Vitro and In Vivo Mouse Paw Oedema Model Studies. Plants (Basel, Switzerland) 12 (6) (2023)
Sigitas Mikutis, Stefanie Lawrinowitz, Christian Kretzer, Lavinia Dunsmore, Laurynas Sketeris, Tiago Rodrigues, Oliver Werz, Gonçalo J L Bernardes
Machine Learning Uncovers Natural Product Modulators of the 5-Lipoxygenase Pathway and Facilitates the Elucidation of Their Biological Mechanisms. ACS chemical biology 19 (1) (2023)
Simona Musella, Danilo D'Avino, Lukas Klaus Peltner, Veronica Di Sarno, Ida Cerqua, Fabrizio Merciai, Vincenzo Vestuto, Tania Ciaglia, Gerardina Smaldone, Francesca Di Matteo, Simone Di Micco, Valeria Napolitano, Giuseppe Bifulco, Giacomo Pepe, Eduardo Maria Sommella, Manuela Giovanna Basilicata, Giovanna Aquino, Isabel Maria Gomez-Monterrey, Pietro Campiglia, Carmine Ostacolo, Fiorentina Roviezzo, Oliver Werz, Antonietta Rossi, Alessia Bertamino
Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis. Journal of medicinal chemistry (2023)
Tuğçe Gür Maz, Beyzanur Koc, Paul M Jordan, Kubra Ibis, Burcu Çalışkan, Oliver Werz, Erden Banoglu
Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors. ACS omega 8 (2) (2023)
Sigitas Mikutis, Stefanie Lawrinowitz, Christian Kretzer, Lavinia Dunsmore, Laurynas Sketeris, Tiago Rodrigues, Oliver Werz, Gonçalo J L Bernardes
Machine Learning Uncovers Natural Product Modulators of the 5-Lipoxygenase Pathway and Facilitates the Elucidation of Their Biological Mechanisms. ACS chemical biology 19 (1) (2023)
Johann Röhrl, Maria-Riera Piqué-Borràs, Manuela Jaklin, Markus Werner, Oliver Werz, Heinke Josef, Hubert Hölz, Aldo Ammendola, Gerald Künstle
Anti-Inflammatory Activities of Arnica montana Planta Tota versus Flower Extracts: Analytical, In Vitro and In Vivo Mouse Paw Oedema Model Studies. Plants (Basel, Switzerland) 12 (6) (2023)
Tarvi Teder, Stefanie König, Rajkumar Singh, Bengt Samuelsson, Oliver Werz, Ulrike Garscha, Jesper Z Haeggström
Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase. International journal of molecular sciences 24 (8) (2023)
Sigitas Mikutis, Stefanie Lawrinowitz, Christian Kretzer, Lavinia Dunsmore, Laurynas Sketeris, Tiago Rodrigues, Oliver Werz, Gonçalo J L Bernardes
Machine Learning Uncovers Natural Product Modulators of the 5-Lipoxygenase Pathway and Facilitates the Elucidation of Their Biological Mechanisms. ACS chemical biology 19 (1) (2023)
Rebecca Riedl, Annika Kühn, Denise Rietz, Betty Hebecker, Karl-Gunther Glowalla, Lukas K Peltner, Paul M Jordan, Oliver Werz, Stefan Lorkowski, Cornelia Wiegand, Maria Wallert
Establishment and Characterization of Mild Atopic Dermatitis in the DNCB-Induced Mouse Model. International journal of molecular sciences 24 (15) (2023)
Max Naumann, Natalie Arend, Rustam R Guliev, Christian Kretzer, Ignacio Rubio, Oliver Werz, Ute Neugebauer
Label-Free Characterization of Macrophage Polarization Using Raman Spectroscopy. International journal of molecular sciences 24 (1) (2023)
Johann Röhrl, Maria-Riera Piqué-Borràs, Manuela Jaklin, Markus Werner, Oliver Werz, Heinke Josef, Hubert Hölz, Aldo Ammendola, Gerald Künstle
Anti-Inflammatory Activities of Arnica montana Planta Tota versus Flower Extracts: Analytical, In Vitro and In Vivo Mouse Paw Oedema Model Studies. Plants (Basel, Switzerland) 12 (6) (2023)
Max Naumann, Natalie Arend, Rustam R Guliev, Christian Kretzer, Ignacio Rubio, Oliver Werz, Ute Neugebauer
Label-Free Characterization of Macrophage Polarization Using Raman Spectroscopy. International journal of molecular sciences 24 (1) (2023)
Tarvi Teder, Stefanie König, Rajkumar Singh, Bengt Samuelsson, Oliver Werz, Ulrike Garscha, Jesper Z Haeggström
Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase. International journal of molecular sciences 24 (8) (2023)
Tarvi Teder, Stefanie König, Rajkumar Singh, Bengt Samuelsson, Oliver Werz, Ulrike Garscha, Jesper Z Haeggström
Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase. International journal of molecular sciences 24 (8) (2023)
Yuping Ning, Wenfei Wang, Paul M Jordan, Stefanie A Barth, Robert Klaus Hofstetter, Jinjin Xu, Ximeng Zhang, Yi Cai, Christian Menge, Xinchun Chen, Oliver Werz
Mycobacterium tuberculosis-Induced Prostaglandin J2 and 15-Deoxy-Prostaglandin J2 Inhibit Inflammatory Signals in Human M1 Macrophages via a Negative Feedback Loop. Journal of immunology (Baltimore, Md. : 1950) (2023)
Patrick Schädel, Anna Czapka, Nadja Gebert, Ilse Denise Jacobsen, Alessandro Ori, Oliver Werz
Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging. Aging cell (2023)
Bodo Speckmann, Jessica Kleinbölting, Friedemann Börner, Paul M Jordan, Oliver Werz, Stefan Pelzer, Heike Tom Dieck, Tanja Wagner, Christiane Schön
Synbiotic Compositions of Bacillus megaterium and Polyunsaturated Fatty Acid Salt Enable Self-Sufficient Production of Specialized Pro-Resolving Mediators. Nutrients 14 (11) (2022)
Mayuri Napagoda, Jana Gerstmeier, Hannah Butschek, Sybille Lorenz, Sudhara De Soyza, Mallique Qader, Ajith Nagahawatte, Weerasinghe Mudiyanselage Dilip Gaya Bandara Wijayaratne, Bernd Schneider, Aleš Svatoš, Lalith Jayasinghe, Andreas Koeberle, Oliver Werz
Plectranthus zeylanicus : A Rich Source of Secondary Metabolites with Antimicrobial, Disinfectant and Anti-Inflammatory Activities. Pharmaceuticals (Basel, Switzerland) 15 (4) (2022)
Anna Czapka, Christian Grune, Patrick Schädel, Vivien Bachmann, Karl Scheuer, Michael Dirauf, Christine Weber, Alexios-Leandros Skaltsounis, Klaus D Jandt, Ulrich S Schubert, Dagmar Fischer, Oliver Werz
Drug delivery of 6-bromoindirubin-3'-glycerol-oxime ether employing poly(D,L-lactide-co-glycolide)-based nanoencapsulation techniques with sustainable solvents. Journal of nanobiotechnology 20 (1) (2022)
Kehong Zhang, Paul Mike Jordan, Simona Pace, Robert Klaus Hofstetter, Markus Werner, Xinchun Chen, Oliver Werz
Modulation of Inflammation-Related Lipid Mediator Pathways by Celastrol During Human Macrophage Polarization. Journal of inflammation research 15 (2022)
Friedemann Börner, Simona Pace, Paul M Jordan, Jana Gerstmeier, Mario Gomez, Antonietta Rossi, Nathaniel C Gilbert, Marcia E Newcomer, Oliver Werz
Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2022)
Paul Zahel, Uwe Beekmann, Thomas Eberlein, Michael Schmitz, Oliver Werz, Dana Kralisch
Bacterial Cellulose-Adaptation of a Nature-Identical Material to the Needs of Advanced Chronic Wound Care. Pharmaceuticals (Basel, Switzerland) 15 (6) (2022)
Friedemann Börner, Simona Pace, Paul M Jordan, Jana Gerstmeier, Mario Gomez, Antonietta Rossi, Nathaniel C Gilbert, Marcia E Newcomer, Oliver Werz
Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (6) (2022)
Marianna Potenza, Assunta Giordano, Maria G Chini, Anella Saviano, Christian Kretzer, Federica Raucci, Marina Russo, Gianluigi Lauro, Stefania Terracciano, Ines Bruno, Maria Iorizzi, Robert Klaus Hofstetter, Simona Pace, Francesco Maione, Oliver Werz, Giuseppe Bifulco
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E 2 and Leukotriene Biosynthesis Inhibitors. ACS medicinal chemistry letters 14 (1) (2022)
Friedemann Börner, Simona Pace, Paul M Jordan, Jana Gerstmeier, Mario Gomez, Antonietta Rossi, Nathaniel C Gilbert, Marcia E Newcomer, Oliver Werz
Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (6) (2022)
Christian Kretzer, Paul M Jordan, Rossella Bilancia, Antonietta Rossi, Tuğçe Gür Maz, Erden Banoglu, Ulrich S Schubert, Oliver Werz
Shifting the Biosynthesis of Leukotrienes Toward Specialized Pro-Resolving Mediators by the 5-Lipoxygenase-Activating Protein (FLAP) Antagonist BRP-201. Journal of inflammation research 15 (2022)
Anella Saviano, Simona De Vita, Maria Giovanna Chini, Noemi Marigliano, Gianluigi Lauro, Gian Marco Casillo, Federica Raucci, Maria Iorizzi, Robert Klaus Hofstetter, Katrin Fischer, Andreas Koeberle, Oliver Werz, Francesco Maione, Giuseppe Bifulco
In Silico, In Vitro, and In Vivo Analysis of Tanshinone IIA and Cryptotanshinone from Salvia miltiorrhiza as Modulators of Cyclooxygenase-2/mPGES-1/Endothelial Prostaglandin EP3 Pathway. Biomolecules 12 (1) (2022)
Ida Cerqua, Simona Musella, Lukas Klaus Peltner, Danilo D'Avino, Veronica Di Sarno, Elisabetta Granato, Vincenzo Vestuto, Rita Di Matteo, Simona Pace, Tania Ciaglia, Rossella Bilancia, Gerardina Smaldone, Francesca Di Matteo, Simone Di Micco, Giuseppe Bifulco, Giacomo Pepe, Manuela Giovanna Basilicata, Manuela Rodriquez, Isabel Maria Gomez-Monterrey, Pietro Campiglia, Carmine Ostacolo, Fiorentina Roviezzo, Oliver Werz, Antonietta Rossi, Alessia Bertamino
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization. Journal of medicinal chemistry 65 (21) (2022)
Erica Gazzillo, Stefania Terracciano, Dafne Ruggiero, Marianna Potenza, Maria Giovanna Chini, Gianluigi Lauro, Katrin Fischer, Robert Klaus Hofstetter, Assunta Giordano, Oliver Werz, Ines Bruno, Giuseppe Bifulco
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation. Molecules (Basel, Switzerland) 27 (12) (2022)
Laura Miek, Paul M Jordan, Kerstin Günther, Simona Pace, Timo Beyer, David Kowalak, Verena Hoerr, Bettina Löffler, Lorena Tuchscherr, Charles N Serhan, Jana Gerstmeier, Oliver Werz
Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid. Immunology 166 (1) (2022)
Friedemann Börner, Simona Pace, Paul M Jordan, Jana Gerstmeier, Mario Gomez, Antonietta Rossi, Nathaniel C Gilbert, Marcia E Newcomer, Oliver Werz
Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (6) (2022)
Lavinia Dunsmore, Claudio D Navo, Julie Becher, Enrique Gil de Montes, Ana Guerreiro, Emily A Hoyt, Libby Brown, Viviane Zelenay, Sigitas Mikutis, Jonathan Cooper, Isaia Barbieri, Stefanie Lawrinowitz, Elise Siouve, Esther Martin, Pedro R Ruivo, Tiago Rodrigues, Filipa P da Cruz, Oliver Werz, George S Vassiliou, Peter Ravn, Gonzalo Jiménez-Osés, Gonçalo J L Bernardes
Controlled masking and targeted release of redox-cycling ortho-quinones via a C-C bond-cleaving 1,6-elimination. Nature chemistry 14 (7) (2022)
Aneliya Knauthe, Sonnhild Mittag, Laura Bloch, Kai Frederik Albring, Martin Schmidt, Oliver Werz, Otmar Huber
Hyperforin and Myrtucommulone Derivatives Act as Natural Modulators of Wnt/β-Catenin Signaling in HCT116 Colon Cancer Cells. International journal of molecular sciences 23 (6) (2022)
Jacob M Wurlitzer, Aleksa Stanišić, Sebastian Ziethe, Paul M Jordan, Kerstin Günther, Oliver Werz, Hajo Kries, Markus Gressler
Macrophage-targeting oligopeptides from Mortierella alpina . Chemical science 13 (31) (2022)
Sümeyye Turanlı, Azize Gizem Ergül, Paul M Jordan, Abdurrahman Olğaç, Burcu Çalışkan, Oliver Werz, Erden Banoglu
Quinazoline-4(3 H )-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition. ACS omega 7 (41) (2022)
Friedemann Börner, Simona Pace, Paul M Jordan, Jana Gerstmeier, Mario Gomez, Antonietta Rossi, Nathaniel C Gilbert, Marcia E Newcomer, Oliver Werz
Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (6) (2022)
Robert Eckenstaler, Anne Ripperger, Michael Hauke, Markus Petermann, Sandra A Hemkemeyer, Edzard Schwedhelm, Süleyman Ergün, Maike Frye, Oliver Werz, Andreas Koeberle, Heike Braun, Ralf A Benndorf
A Thromboxane A 2 Receptor-Driven COX-2-Dependent Feedback Loop That Affects Endothelial Homeostasis and Angiogenesis. Arteriosclerosis, thrombosis, and vascular biology 42 (4) (2022)
Friedemann Börner, Simona Pace, Paul M Jordan, Jana Gerstmeier, Mario Gomez, Antonietta Rossi, Nathaniel C Gilbert, Marcia E Newcomer, Oliver Werz
Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (6) (2022)
Marianna Potenza, Assunta Giordano, Maria G Chini, Anella Saviano, Christian Kretzer, Federica Raucci, Marina Russo, Gianluigi Lauro, Stefania Terracciano, Ines Bruno, Maria Iorizzi, Robert Klaus Hofstetter, Simona Pace, Francesco Maione, Oliver Werz, Giuseppe Bifulco
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E 2 and Leukotriene Biosynthesis Inhibitors. ACS medicinal chemistry letters 14 (1) (2022)
Friedemann Börner, Simona Pace, Paul M Jordan, Jana Gerstmeier, Mario Gomez, Antonietta Rossi, Nathaniel C Gilbert, Marcia E Newcomer, Oliver Werz
Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (6) (2022)
Theresa Wolfram, Leonie M Weidenbach, Johanna Adolf, Maria Schwarz, Patrick Schädel, André Gollowitzer, Oliver Werz, Andreas Koeberle, Anna Patricia Kipp, Solveigh C Koeberle
The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages. International journal of molecular sciences 22 (20) (2021)
Hans Jagusch, Markus Werner, Duco Koenis, Jesmond Dalli, Oliver Werz, Georg Pohnert
14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae. ACS pharmacology & translational science 4 (3) (2021)
Friedemann Börner, Markus Werner, Johannes Ertelt, Jürgen Meins, Mona Abdel-Tawab, Oliver Werz
Analysis of Boswellic Acid Contents and Related Pharmacological Activities of Frankincense-Based Remedies That Modulate Inflammation. Pharmaceuticals (Basel, Switzerland) 14 (7) (2021)
Kehong Zhang, Simona Pace, Paul M Jordan, Lukas K Peltner, Alexander Weber, Dagmar Fischer, Robert K Hofstetter, Xinchun Chen, Oliver Werz
Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides. Biomolecules 11 (5) (2021)
Antje Vollrath, Christian Kretzer, Baerbel Beringer-Siemers, Blerina Shkodra, Justyna A Czaplewska, Damiano Bandelli, Steffi Stumpf, Stephanie Hoeppener, Christine Weber, Oliver Werz, Ulrich S Schubert
Effect of Crystallinity on the Properties of Polycaprolactone Nanoparticles Containing the Dual FLAP/mPEGS-1 Inhibitor BRP-187. Polymers 13 (15) (2021)
Paul M Jordan, Emeline van Goethem, Andrea M Müller, Kathrin Hemmer, Virginie Gavioli, Vincent Baillif, Yvonne Burmeister, Natascha Krömmelbein, Marc Dubourdeau, Bernd Seilheimer, Oliver Werz
The Natural Combination Medicine Traumeel (Tr14) Improves Resolution of Inflammation by Promoting the Biosynthesis of Specialized Pro-Resolving Mediators. Pharmaceuticals (Basel, Switzerland) 14 (11) (2021)
Jana Fischer, Mark S Gresnigt, Oliver Werz, Bernhard Hube, Ulrike Garscha
Candida albicans-induced leukotriene biosynthesis in neutrophils is restricted to the hyphal morphology. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35 (10) (2021)
Paul M Jordan, Oliver Werz
Specialized pro-resolving mediators: biosynthesis and biological role in bacterial infections. The FEBS journal (2021)
Jessica Hoff, Berit Karl, Jana Gerstmeier, Uwe Beekmann, Lisa Schmölz, Friedemann Börner, Dana Kralisch, Michael Bauer, Oliver Werz, Dagmar Fischer, Stefan Lorkowski, Adrian Tibor Press
Controlled Release of the α-Tocopherol-Derived Metabolite α-13'-Carboxychromanol from Bacterial Nanocellulose Wound Cover Improves Wound Healing. Nanomaterials (Basel, Switzerland) 11 (8) (2021)
Anke Katharina Müller, Franziska Albrecht, Carsten Rohrer, Andreas Koeberle, Oliver Werz, Wiebke Schlörmann, Michael Glei, Stefan Lorkowski, Maria Wallert
Olive Oil Extracts and Oleic Acid Attenuate the LPS-Induced Inflammatory Response in Murine RAW264.7 Macrophages but Induce the Release of Prostaglandin E2. Nutrients 13 (12) (2021)
Christian Kretzer, Blerina Shkodra, Paul Klemm, Paul M Jordan, Daniel Schröder, Gizem Cinar, Antje Vollrath, Stephanie Schubert, Ivo Nischang, Stephanie Hoeppener, Steffi Stumpf, Erden Banoglu, Frederike Gladigau, Rossella Bilancia, Antonietta Rossi, Christian Eggeling, Ute Neugebauer, Ulrich Sigmar Schubert, Oliver Werz
Ethoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist in human leukocytes and blood. Cellular and molecular life sciences : CMLS 79 (1) (2021)
Konstantin Neukirch, Khaled Alsabil, Chau-Phi Dinh, Rossella Bilancia, Martin Raasch, Alexia Ville, Ida Cerqua, Guillaume Viault, Dimitri Bréard, Simona Pace, Veronika Temml, Elena Brunner, Paul M Jordan, Marta C Marques, Konstantin Loeser, André Gollowitzer, Stephan Permann, Jana Gerstmeier, Stefan Lorkowski, Hermann Stuppner, Ulrike Garscha, Tiago Rodrigues, Gonçalo J L Bernardes, Daniela Schuster, Denis Séraphin, Pascal Richomme, Antonietta Rossi, Alexander S Mosig, Fiorentina Roviezzo, Oliver Werz, Jean-Jacques Helesbeux, Andreas Koeberle
Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation. Journal of medicinal chemistry 64 (15) (2021)
Klarissa Hanja Stürner, Oliver Werz, Andreas Koeberle, Markus Otto, Ole Pless, Frank Leypoldt, Friedemann Paul, Christoph Heesen
Lipid Mediator Profiles Predict Response to Therapy with an Oral Frankincense Extract in Relapsing-Remitting Multiple Sclerosis. Scientific reports 10 (1) (2020)
Mira Behnke, Antje Vollrath, Lea Klepsch, Baerbel Beringer-Siemers, Steffi Stumpf, Justyna A Czaplewska, Stephanie Hoeppener, Oliver Werz, Ulrich S Schubert
Optimized Encapsulation of the FLAP/PGES-1 Inhibitor BRP-187 in PVA-Stabilized PLGA Nanoparticles Using Microfluidics. Polymers 12 (11) (2020)
Fabian Mayr, Gabriele Möller, Ulrike Garscha, Jana Fischer, Patricia Rodríguez Castaño, Silvia G Inderbinen, Veronika Temml, Birgit Waltenberger, Stefan Schwaiger, Rolf W Hartmann, Christian Gege, Stefan Martens, Alex Odermatt, Amit V Pandey, Oliver Werz, Jerzy Adamski, Hermann Stuppner, Daniela Schuster
Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction. International journal of molecular sciences 21 (19) (2020)
Lília Espada, Alexander Dakhovnik, Prerana Chaudhari, Asya Martirosyan, Laura Miek, Tetiana Poliezhaieva, Yvonne Schaub, Ashish Nair, Nadia Döring, Norman Rahnis, Oliver Werz, Andreas Koeberle, Joanna Kirkpatrick, Alessandro Ori, Maria A Ermolaeva
Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans. Nature metabolism 2 (11) (2020)
Thomas Hanke, Sun-Yee Cheung, Whitney Kilu, Jan Heering, Xiaomin Ni, Viktoria Planz, Simone Schierle, Giuseppe Faudone, Marius Friedrich, Marek Wanior, Oliver Werz, Maike Windbergs, Ewgenij Proschak, Manfred Schubert-Zsilavecz, Apirat Chaikuad, Stefan Knapp, Daniel Merk
A Selective Modulator of Peroxisome Proliferator-Activated Receptor γ with an Unprecedented Binding Mode. Journal of medicinal chemistry 63 (9) (2020)
Nathaniel C Gilbert, Jana Gerstmeier, Erin E Schexnaydre, Friedemann Börner, Ulrike Garscha, David B Neau, Oliver Werz, Marcia E Newcomer
Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products. Nature chemical biology 16 (7) (2020)
Anja Traeger, Susanna Voelker, Blerina Shkodra-Pula, Christian Kretzer, Stephanie Schubert, Michael Gottschaldt, Ulrich Sigmar Schubert, Oliver Werz
Improved Bioactivity of the Natural Product 5-Lipoxygenase Inhibitor Hyperforin by Encapsulation into Polymeric Nanoparticles. Molecular pharmaceutics 17 (3) (2020)
Markus Werner, Simona Pace, Anna Czapka, Paul M Jordan, Jana Gerstmeier, Andreas Koeberle, Oliver Werz
Communication between human macrophages and epithelial cancer cell lines dictates lipid mediator biosynthesis. Cellular and molecular life sciences : CMLS 77 (21) (2020)
Uwe Beekmann, Paul Zahel, Berit Karl, Lisa Schmölz, Friedemann Börner, Jana Gerstmeier, Oliver Werz, Stefan Lorkowski, Cornelia Wiegand, Dagmar Fischer, Dana Kralisch
Modified Bacterial Cellulose Dressings to Treat Inflammatory Wounds. Nanomaterials (Basel, Switzerland) 10 (12) (2020)
Abdurrahman Olgac, Andrea Carotti, Christian Kretzer, Stephanie Zergiebel, Andreas Seeling, Ulrike Garscha, Oliver Werz, Antonio Macchiarulo, Erden Banoglu
Discovery of Novel 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors by Exploiting a Multistep Virtual Screening Protocol. Journal of chemical information and modeling 60 (3) (2020)