Joshua M Dempster (Joshua Dempster)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 21

Top Topics

Dna Methylation

Top Venues

Nature communications

Cancer discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Alessandro Vinceti, Raffaele M Iannuzzi, Isabella Boyle, Lucia Trastulla, Catarina D Campbell, Francisca Vazquez, Joshua M Dempster, Francesco Iorio
A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data. Genome biology 25 (1) (2024)
Alessandro Vinceti, Raffaele M Iannuzzi, Isabella Boyle, Lucia Trastulla, Catarina D Campbell, Francisca Vazquez, Joshua M Dempster, Francesco Iorio
A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data. Genome biology 25 (1) (2024)
Alessandro Vinceti, Raffaele M Iannuzzi, Isabella Boyle, Lucia Trastulla, Catarina D Campbell, Francisca Vazquez, Joshua M Dempster, Francesco Iorio
A benchmark of computational methods for correcting biases of established and unknown origin in CRISPR-Cas9 screening data. Genome biology 25 (1) (2024)
Sean A Misek, Aaron Fultineer, Jérémie Kalfon, Javad Noorbakhsh, Isabella Boyle, Priyanka Roy, Joshua M Dempster, Lia Petronio, Katherine Huang, Alham Saadat, Thomas Green, Adam Brown, John G Doench, David E Root, James M McFarland, Rameen Beroukhim, Jesse S Boehm
Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries. Nature communications 15 (1) (2024)
Sean A Misek, Aaron Fultineer, Jérémie Kalfon, Javad Noorbakhsh, Isabella Boyle, Priyanka Roy, Joshua M Dempster, Lia Petronio, Katherine Huang, Alham Saadat, Thomas Green, Adam Brown, John G Doench, David E Root, James M McFarland, Rameen Beroukhim, Jesse S Boehm
Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries. Nature communications 15 (1) (2024)
Sean A Misek, Aaron Fultineer, Jérémie Kalfon, Javad Noorbakhsh, Isabella Boyle, Priyanka Roy, Joshua M Dempster, Lia Petronio, Katherine Huang, Alham Saadat, Thomas Green, Adam Brown, John G Doench, David E Root, James M McFarland, Rameen Beroukhim, Jesse S Boehm
Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries. Nature communications 15 (1) (2024)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L Downey-Kopyscinski, Geoffrey M Matthews, Benjamin G Barwick, Vilas A Gupta, Daphné Dupéré-Richer, Shizuka Yamano, Yiguo Hu, Michal Sheffer, Eugen Dhimolea, Olga Dashevsky, Sara Gandolfi, Kazuya Ishiguro, Robin M Meyers, Jordan G Bryan, Neekesh V Dharia, Paul J Hengeveld, Johanna B Brüggenthies, Huihui Tang, Andrew J Aguirre, Quinlan L Sievers, Benjamin L Ebert, Brian J Glassner, Christopher J Ott, James E Bradner, Nicholas P Kwiatkowski, Daniel Auclair, Joan Levy, Jonathan J Keats, Richard W J Groen, Nathanael S Gray, Aedin C Culhane, James M McFarland, Joshua M Dempster, Jonathan D Licht, Lawrence H Boise, William C Hahn, Francisca Vazquez, Aviad Tsherniak, Constantine S Mitsiades
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature cancer 4 (5) (2023)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Tanaz Sharifnia, Mathias J Wawer, Amy Goodale, Yenarae Lee, Mariya Kazachkova, Joshua M Dempster, Sandrine Muller, Joan Levy, Daniel M Freed, Josh Sommer, Jérémie Kalfon, Francisca Vazquez, William C Hahn, David E Root, Paul A Clemons, Stuart L Schreiber
Mapping the landscape of genetic dependencies in chordoma. Nature communications 14 (1) (2023)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A ubiquitination cascade regulating the integrated stress response and survival in carcinomas. Cancer discovery (2022)
Kenneth Eagle, Taku Harada, Jérémie Kalfon, Monika W Perez, Yaser Heshmati, Jazmin Ewers, Jošt Vrabič Koren, Joshua M Dempster, Guillaume Kugener, Vikram R Paralkar, Charles Y Lin, Neekesh V Dharia, Kimberly Stegmaier, Stuart H Orkin, Maxim Pimkin
Transcriptional Plasticity Drives Leukemia Immune Escape. Blood cancer discovery 3 (5) (2022)
Ruitong Li, Olaf Klingbeil, Davide Monducci, Michael J Young, Diego J Rodriguez, Zaid Bayyat, Joshua M Dempster, Devishi Kesar, Xiaoping Yang, Mahdi Zamanighomi, Christopher R Vakoc, Takahiro Ito, William R Sellers
Comparative optimization of combinatorial CRISPR screens. Nature communications 13 (1) (2022)
Eshini Panditharatna, Joana G Marques, Tingjian Wang, Maria C Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V Dharia, Deyao Li, Samantha E Hoffman, Guillaume Kugener, McKenzie L Shaw, Hafsa M Mire, Olivia A Hack, Joshua M Dempster, Caleb A Lareau, Lingling Dai, Logan H Sigua, Michael A Quezada, Ann-Catherine J Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Frederica Piccioni, John G Doench, David E Root, Jamie N Anastas, Kristen L Jones, Amy Saur Conway, Sylwia A Stopka, Michael S Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P Jerome, Nathan D Mathewson, Sirano Dhe-Paganon, Mario L Suvà, Angel Montero Carcaboso, Cinzia Lavarino, Jaume Catala-Mora, Quang-De Nguyen, Keith L Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y R Agar, Kimberly Stegmaier, Charles D Stiles, Michelle Monje, Todd R Golub, Jun Qi, Mariella G Filbin
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma. Cancer discovery 12 (12) (2022)
Daniel P Bondeson, Brenton R Paolella, Adhana Asfaw, Michael V Rothberg, Thomas A Skipper, Carly Langan, Gabriel Mesa, Alfredo Gonzalez, Lauren E Surface, Kentaro Ito, Mariya Kazachkova, William N Colgan, Allison Warren, Joshua M Dempster, John Michael Krill-Burger, Maria Ericsson, Andrew A Tang, Iris Fung, Emily S Chambers, Mai Abdusamad, Nancy Dumont, John G Doench, Federica Piccioni, David E Root, Jesse S Boehm, William C Hahn, Michael Mannstadt, James M McFarland, Francisca Vazquez, Todd R Golub
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. Nature cancer 3 (6) (2022)
Joshua M Dempster, Isabella Boyle, Francisca Vazquez, David E Root, Jesse S Boehm, William C Hahn, Aviad Tsherniak, James M McFarland
Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects. Genome biology 22 (1) (2021)
Clare F Malone, Neekesh V Dharia, Guillaume Kugener, Alexandra B Forman, Michael V Rothberg, Mai Abdusamad, Alfredo Gonzalez, Miljan Kuljanin, Amanda L Robichaud, Amy Saur Conway, Joshua M Dempster, Brenton R Paolella, Nancy Dumont, Volker Hovestadt, Joseph D Mancias, Scott T Younger, David E Root, Todd R Golub, Francisca Vazquez, Kimberly Stegmaier
Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer. Cancer discovery 11 (9) (2021)
Clare Pacini, Joshua M Dempster, Isabella Boyle, Emanuel Gonçalves, Hanna Najgebauer, Emre Karakoc, Dieudonne van der Meer, Andrew Barthorpe, Howard Lightfoot, Patricia Jaaks, James M McFarland, Mathew J Garnett, Aviad Tsherniak, Francesco Iorio
Integrated cross-study datasets of genetic dependencies in cancer. Nature communications 12 (1) (2021)
Neekesh V Dharia, Guillaume Kugener, Lillian M Guenther, Clare F Malone, Adam D Durbin, Andrew L Hong, Thomas P Howard, Pratiti Bandopadhayay, Caroline S Wechsler, Iris Fung, Allison C Warren, Joshua M Dempster, John Michael Krill-Burger, Brenton R Paolella, Phoebe Moh, Nishant Jha, Andrew Tang, Phillip G Montgomery, Jesse S Boehm, William C Hahn, Charles W M Roberts, James M McFarland, Aviad Tsherniak, Todd R Golub, Francisca Vazquez, Kimberly Stegmaier
A first-generation pediatric cancer dependency map. Nature genetics 53 (4) (2021)
Joshua M Dempster, Clare Pacini, Sasha Pantel, Fiona M Behan, Thomas Green, John Michael Krill-Burger, Charlotte M Beaver, Scott T Younger, Victor Zhivich, Hanna Najgebauer, Felicity Allen, Emanuel Gonçalves, Rebecca Shepherd, John G Doench, Kosuke Yusa, Francisca Vazquez, Leopold Parts, Jesse S Boehm, Todd R Golub, William C Hahn, David E Root, Mathew J Garnett, Aviad Tsherniak, Francesco Iorio
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets. Nature communications 10 (1) (2019)