Prafulla C Gokhale

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 23

Top Topics

Small Cell Lung Cancer

Lipopolysaccharide Induced

Top Venues

Communications biology

Cancer discovery

Cancer research

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Caroline G Fahey, Keiichi Ota, Navin R Mahadevan, Yingxiao Shi, Shin Saito, Kei Mizuno, Tran C Thai, Nobunari Sasaki, Mizuki Homme, Choudhury Fabliha B Yusuf, Adam Kashishian, Jipsa Panchal, Min Wang, Benjamin J Wolf, Thanh U Barbie, Cloud P Paweletz, Prafulla C Gokhale, David R Liu, Ravindra Uppaluri, Shunsuke Kitajima, Jennifer Cain, David A Barbie
TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity. Cancer discovery (2024)
Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Caroline G Fahey, Keiichi Ota, Navin R Mahadevan, Yingxiao Shi, Shin Saito, Kei Mizuno, Tran C Thai, Nobunari Sasaki, Mizuki Homme, Choudhury Fabliha B Yusuf, Adam Kashishian, Jipsa Panchal, Min Wang, Benjamin J Wolf, Thanh U Barbie, Cloud P Paweletz, Prafulla C Gokhale, David R Liu, Ravindra Uppaluri, Shunsuke Kitajima, Jennifer Cain, David A Barbie
TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity. Cancer discovery (2024)
Jelena Levi, Caroline Guglielmetti, Timothy J Henrich, John C Yoon, Prafulla C Gokhale, David A Reardon, Juliet Packiasamy, Lyna Huynh, Hilda Cabrera, Marisa Ruzevich, Joseph Blecha, Michael J Peluso, Tony L Huynh, Sung-Min An, Mark Dornan, Anthony P Belanger, Quang-Dé Nguyen, Youngho Seo, Hong Song, Myriam M Chaumeil, Henry F VanBrocklin, Hee-Don Chae
[ 18 F]F-AraG imaging reveals association between neuroinflammation and brown- and bone marrow adipose tissue. Communications biology 7 (1) (2024)
Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Caroline G Fahey, Keiichi Ota, Navin R Mahadevan, Yingxiao Shi, Shin Saito, Kei Mizuno, Tran C Thai, Nobunari Sasaki, Mizuki Homme, Choudhury Fabliha B Yusuf, Adam Kashishian, Jipsa Panchal, Min Wang, Benjamin J Wolf, Thanh U Barbie, Cloud P Paweletz, Prafulla C Gokhale, David R Liu, Ravindra Uppaluri, Shunsuke Kitajima, Jennifer Cain, David A Barbie
TREX1 Inactivation Unleashes Cancer Cell STING-Interferon Signaling and Promotes Antitumor Immunity. Cancer discovery 14 (5) (2024)
Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Jelena Levi, Caroline Guglielmetti, Timothy J Henrich, John C Yoon, Prafulla C Gokhale, David A Reardon, Juliet Packiasamy, Lyna Huynh, Hilda Cabrera, Marisa Ruzevich, Joseph Blecha, Michael J Peluso, Tony L Huynh, Sung-Min An, Mark Dornan, Anthony P Belanger, Quang-Dé Nguyen, Youngho Seo, Hong Song, Myriam M Chaumeil, Henry F VanBrocklin, Hee-Don Chae
[ 18 F]F-AraG imaging reveals association between neuroinflammation and brown- and bone marrow adipose tissue. Communications biology 7 (1) (2024)
Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Caroline G Fahey, Keiichi Ota, Navin R Mahadevan, Yingxiao Shi, Shin Saito, Kei Mizuno, Tran C Thai, Nobunari Sasaki, Mizuki Homme, Choudhury Fabliha B Yusuf, Adam Kashishian, Jipsa Panchal, Min Wang, Benjamin J Wolf, Thanh U Barbie, Cloud P Paweletz, Prafulla C Gokhale, David R Liu, Ravindra Uppaluri, Shunsuke Kitajima, Jennifer Cain, David A Barbie
TREX1 Inactivation Unleashes Cancer Cell STING-Interferon Signaling and Promotes Antitumor Immunity. Cancer discovery 14 (5) (2024)
Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Caroline G Fahey, Keiichi Ota, Navin R Mahadevan, Yingxiao Shi, Shin Saito, Kei Mizuno, Tran C Thai, Nobunari Sasaki, Mizuki Homme, Choudhury Fabliha B Yusuf, Adam Kashishian, Jipsa Panchal, Min Wang, Benjamin J Wolf, Thanh U Barbie, Cloud P Paweletz, Prafulla C Gokhale, David R Liu, Ravindra Uppaluri, Shunsuke Kitajima, Jennifer Cain, David A Barbie
TREX1 Inactivation Unleashes Cancer Cell STING-Interferon Signaling and Promotes Antitumor Immunity. Cancer discovery 14 (5) (2024)
Mubin Tarannum, Khanhlinh Dinh, Juliana Vergara Cadavid, Grace Birch, Yasmin Z Abdulhamid, Isabel E Kaplan, Oyku Ay, Andreia Maia, Owen Beaver, Michal Sheffer, Roman Shapiro, Alaa Kassim Ali, Han Dong, James Dongjoo Ham, Eden Bobilev, Sydney James, Amy B Cameron, Quang-De Nguyen, Suthakar Ganapathy, Chayapatou Chayawatto, John Koreth, Cloud P Paweletz, Prafulla C Gokhale, David A Barbie, Ursula A Matulonis, Robert J Soiffer, Jerome Ritz, Rebecca L Porter, Jianzhu Chen, Rizwan Romee
CAR memory-like NK cells targeting the membrane proximal domain of mesothelin demonstrate promising activity in ovarian cancer. Science advances 10 (28) (2024)
Jelena Levi, Caroline Guglielmetti, Timothy J Henrich, John C Yoon, Prafulla C Gokhale, David A Reardon, Juliet Packiasamy, Lyna Huynh, Hilda Cabrera, Marisa Ruzevich, Joseph Blecha, Michael J Peluso, Tony L Huynh, Sung-Min An, Mark Dornan, Anthony P Belanger, Quang-Dé Nguyen, Youngho Seo, Hong Song, Myriam M Chaumeil, Henry F VanBrocklin, Hee-Don Chae
[ 18 F]F-AraG imaging reveals association between neuroinflammation and brown- and bone marrow adipose tissue. Communications biology 7 (1) (2024)
Mubin Tarannum, Khanhlinh Dinh, Juliana Vergara Cadavid, Grace Birch, Yasmin Z Abdulhamid, Isabel E Kaplan, Oyku Ay, Andreia Maia, Owen Beaver, Michal Sheffer, Roman Shapiro, Alaa Kassim Ali, Han Dong, James Dongjoo Ham, Eden Bobilev, Sydney James, Amy B Cameron, Quang-De Nguyen, Suthakar Ganapathy, Chayapatou Chayawatto, John Koreth, Cloud P Paweletz, Prafulla C Gokhale, David A Barbie, Ursula A Matulonis, Robert J Soiffer, Jerome Ritz, Rebecca L Porter, Jianzhu Chen, Rizwan Romee
CAR memory-like NK cells targeting the membrane proximal domain of mesothelin demonstrate promising activity in ovarian cancer. Science advances 10 (28) (2024)
Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Caroline G Fahey, Keiichi Ota, Navin R Mahadevan, Yingxiao Shi, Shin Saito, Kei Mizuno, Tran C Thai, Nobunari Sasaki, Mizuki Homme, Choudhury Fabliha B Yusuf, Adam Kashishian, Jipsa Panchal, Min Wang, Benjamin J Wolf, Thanh U Barbie, Cloud P Paweletz, Prafulla C Gokhale, David R Liu, Ravindra Uppaluri, Shunsuke Kitajima, Jennifer Cain, David A Barbie
TREX1 Inactivation Unleashes Cancer Cell STING-Interferon Signaling and Promotes Antitumor Immunity. Cancer discovery 14 (5) (2024)
Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Jelena Levi, Caroline Guglielmetti, Timothy J Henrich, John C Yoon, Prafulla C Gokhale, David A Reardon, Juliet Packiasamy, Lyna Huynh, Hilda Cabrera, Marisa Ruzevich, Joseph Blecha, Michael J Peluso, Tony L Huynh, Sung-Min An, Mark Dornan, Anthony P Belanger, Quang-Dé Nguyen, Youngho Seo, Hong Song, Myriam M Chaumeil, Henry F VanBrocklin, Hee-Don Chae
[ 18 F]F-AraG imaging reveals association between neuroinflammation and brown- and bone marrow adipose tissue. Communications biology 7 (1) (2024)
Yeying Huang, R Taylor Durall, Nhi M Luong, Hans J Hertzler, Julianna Huang, Prafulla C Gokhale, Brittaney A Leeper, Nicole S Persky, David E Root, Praju Vikas Anekal, Paula Montero Llopis, Clement N David, Jeffery L Kutok, Alejandra Raimondi, Karan Saluja, Jia Luo, Cynthia A Zahnow, Biniam Adane, Kimberly Stegmaier, Catherine E Hawkins, Christopher Ponne, Quan Le, Geoffrey I Shapiro, Madeleine E Lemieux, Kyle P Eagen, Christopher A French
EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes. Cancer research (2023)
R Taylor Durall, Julianna Huang, Luke Wojenski, Yeying Huang, Prafulla C Gokhale, Brittaney A Leeper, Joshua O Nash, Pedro L Ballester, Scott Davidson, Adam Shlien, Emmanuel Sotirakis, Fabien Bertaux, Vincent Dubus, Jia Luo, Catherine J Wu, Derin B Keskin, Kyle P Eagen, Geoffrey I Shapiro, Christopher A French
The BRD4-NUT fusion alone drives malignant transformation of NUT carcinoma. Cancer research (2023)
Adrian Mariño-Enriquez, Jan Philipp Novotny, Doga C Gulhan, Isabella Klooster, Antuan V Tran, Macy Kasbo, Meijun Z Lundberg, Wen-Bin Ou, Derrick L Tao, Daniel F Pilco-Janeta, Victor Y Mao, Frank T Zenke, Brittaney A Leeper, Prafulla C Gokhale, Glenn S Cowley, Laurence H Baker, Karla V Ballman, David E Root, Joachim Albers, Peter J Park, Suzanne George, Jonathan A Fletcher
Hyper-Dependence on NHEJ Enables Synergy Between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Yoshihisa Kobayashi, Chhayheng Chhoeu, Jiaqi Li, Kristin S Price, Lesli A Kiedrowski, Jamie L Hutchins, Aaron I Hardin, Zihan Wei, Fangxin Hong, Magda Bahcall, Prafulla C Gokhale, Pasi A Janne
Silent mutations reveal therapeutic vulnerability in RAS Q61 cancers. Nature 603 (7900) (2022)
Ciric To, Tyler S Beyett, Jaebong Jang, William W Feng, Magda Bahcall, Heidi M Haikala, Bo H Shin, David E Heppner, Jaimin K Rana, Brittaney A Leeper, Kara M Soroko, Michael J Poitras, Prafulla C Gokhale, Yoshihisa Kobayashi, Kamal Wahid, Kari J Kurppa, Thomas W Gero, Michael D Cameron, Atsuko Ogino, Mierzhati Mushajiang, Chunxiao Xu, Yanxi Zhang, David A Scott, Michael J Eck, Nathanael S Gray, Pasi A Janne
An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer. Nature cancer 3 (4) (2022)
Ryohei Yoshida, Maria Saigí, Tetsuo Tani, Benjamin F Springer, Hirofumi Shibata, Shunsuke Kitajima, Navin R Mahadevan, Marco Campisi, Jong Wook Kim, Yoshihisa Kobayashi, Tran C Thai, Koji Haratani, Yurie Yamamoto, Shriram K Sundararaman, Erik H Knelson, Amir Vajdi, Israel Cañadas, Ravindra Uppaluri, Cloud P Paweletz, Juan J Miret, Patrick H Lizotte, Prafulla C Gokhale, Pasi A Janne, David A Barbie
MET-Induced CD73 Restrains STING-Mediated Immunogenicity of EGFR-Mutant Lung Cancer. Cancer research 82 (21) (2022)
Pınar Özden Eser, Raymond M Paranal, Jieun Son, Elena Ivanova, Yanan Kuang, Heidi M Haikala, Ciric To, Jeffrey J Okoro, Kshiti H Dholakia, Jihyun Choi, Yoonji Eum, Atsuko Ogino, Pavlos Missios, Dalia Ercan, Man Xu, Michael J Poitras, Stephen Wang, Kenneth H Ngo, Michael Dills, Masahiko Yanagita, Timothy Lopez, Mika Lin, Jeanelle Tsai, Nicolas Floch, Emily S Chambers, Jennifer Heng, Rana Anjum, Alison D Santucci, Kesi S Michael, Alwin G Schuller, Darren Ae Cross, Paul D Smith, Geoffrey R Oxnard, David A Barbie, Lynette M Sholl, Magda Bahcall, Sangeetha Palakurthi, Prafulla C Gokhale, Cloud P Paweletz, George Q Daley, Pasi A Janne
Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer. Science translational medicine 13 (609) (2021)
Panagiotis A Konstantinopoulos, Su-Chun Cheng, Jeffrey G Supko, Madeline Polak, Andrea E Wahner-Hendrickson, S Percy Ivy, Brittany Bowes, Hannah Sawyer, Patrice Basada, Martin Hayes, Jennifer Curtis, Neil Horowitz, Alexi A Wright, Susana M Campos, Elena V Ivanova, Cloud P Paweletz, Sangeetha Palakurthi, Joyce F Liu, Alan D' Andrea, Prafulla C Gokhale, Dipanjan Chowdhury, Ursula A Matulonis, Geoffrey I Shapiro
Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours. British journal of cancer (2021)