Wolfgang Huber (W Huber)

Publication Activity (10 Years)

Years Active: 2013-2024
Publications (10 Years): 38

Top Topics

Mass Spectrometry

Binding Protein

Chronic Lymphocytic Leukemia

Histone Deacetylase

Top Venues

Nature cell biology

Nature communications

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Tobias Roider, Marc-Andrea Baertsch, Donnacha Fitzgerald, Harald Vöhringer, Berit J Brinkmann, Felix Czernilofsky, Mareike Knoll, Laura Llaó-Cid, Anna Mathioudaki, Bianca Faßbender, Maxime Herbon, Tobias Lautwein, Peter-Martin Bruch, Nora Liebers, Christian M Schürch, Verena Passerini, Marc Seifert, Alexander Brobeil, Gunhild Mechtersheimer, Carsten Muller-Tidow, Oliver Weigert, Martina Seiffert, Garry P Nolan, Wolfgang Huber, Sascha Dietrich
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities. Nature cell biology 26 (3) (2024)
Tobias Roider, Marc-Andrea Baertsch, Donnacha Fitzgerald, Harald Vöhringer, Berit J Brinkmann, Felix Czernilofsky, Mareike Knoll, Laura Llaó-Cid, Anna Mathioudaki, Bianca Faßbender, Maxime Herbon, Tobias Lautwein, Peter-Martin Bruch, Nora Liebers, Christian M Schürch, Verena Passerini, Marc Seifert, Alexander Brobeil, Gunhild Mechtersheimer, Carsten Muller-Tidow, Oliver Weigert, Martina Seiffert, Garry P Nolan, Wolfgang Huber, Sascha Dietrich
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities. Nature cell biology 26 (3) (2024)
Monika Pepelnjak, Britta Velten, Nicolas Näpflin, Tatjana von Rosen, Umberto Capasso Palmiero, Jeong Hoon Ko, Heather D Maynard, Paolo Arosio, Eilika Weber-Ban, Natalie de Souza, Wolfgang Huber, Paola Picotti
In situ analysis of osmolyte mechanisms of proteome thermal stabilization. Nature chemical biology 20 (8) (2024)
Tobias Roider, Marc-Andrea Baertsch, Donnacha Fitzgerald, Harald Vöhringer, Berit J Brinkmann, Felix Czernilofsky, Mareike Knoll, Laura Llaó-Cid, Anna Mathioudaki, Bianca Faßbender, Maxime Herbon, Tobias Lautwein, Peter-Martin Bruch, Nora Liebers, Christian M Schürch, Verena Passerini, Marc Seifert, Alexander Brobeil, Gunhild Mechtersheimer, Carsten Muller-Tidow, Oliver Weigert, Martina Seiffert, Garry P Nolan, Wolfgang Huber, Sascha Dietrich
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities. Nature cell biology 26 (3) (2024)
Tobias Roider, Marc-Andrea Baertsch, Donnacha Fitzgerald, Harald Vöhringer, Berit J Brinkmann, Felix Czernilofsky, Mareike Knoll, Laura Llaó-Cid, Anna Mathioudaki, Bianca Faßbender, Maxime Herbon, Tobias Lautwein, Peter-Martin Bruch, Nora Liebers, Christian M Schürch, Verena Passerini, Marc Seifert, Alexander Brobeil, Gunhild Mechtersheimer, Carsten Muller-Tidow, Oliver Weigert, Martina Seiffert, Garry P Nolan, Wolfgang Huber, Sascha Dietrich
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities. Nature cell biology 26 (3) (2024)
Tobias Roider, Marc-Andrea Baertsch, Donnacha Fitzgerald, Harald Vöhringer, Berit J Brinkmann, Felix Czernilofsky, Mareike Knoll, Laura Llaó-Cid, Anna Mathioudaki, Bianca Faßbender, Maxime Herbon, Tobias Lautwein, Peter-Martin Bruch, Nora Liebers, Christian M Schürch, Verena Passerini, Marc Seifert, Alexander Brobeil, Gunhild Mechtersheimer, Carsten Muller-Tidow, Oliver Weigert, Martina Seiffert, Garry P Nolan, Wolfgang Huber, Sascha Dietrich
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities. Nature cell biology (2024)
Monika Pepelnjak, Britta Velten, Nicolas Näpflin, Tatjana von Rosen, Umberto Capasso Palmiero, Jeong Hoon Ko, Heather D Maynard, Paolo Arosio, Eilika Weber-Ban, Natalie de Souza, Wolfgang Huber, Paola Picotti
In situ analysis of osmolyte mechanisms of proteome thermal stabilization. Nature chemical biology 20 (8) (2024)
Monika Pepelnjak, Britta Velten, Nicolas Näpflin, Tatjana von Rosen, Umberto Capasso Palmiero, Jeong Hoon Ko, Heather D Maynard, Paolo Arosio, Eilika Weber-Ban, Natalie de Souza, Wolfgang Huber, Paola Picotti
In situ analysis of osmolyte mechanisms of proteome thermal stabilization. Nature chemical biology 20 (8) (2024)
Luca Marconato, Giovanni Palla, Kevin A Yamauchi, Isaac Virshup, Elyas Heidari, Tim Treis, Wouter-Michiel Vierdag, Marcella Toth, Sonja Stockhaus, Rahul B Shrestha, Benjamin Rombaut, Lotte Pollaris, Laurens Lehner, Harald Vöhringer, Ilia Kats, Yvan Saeys, Sinem K Saka, Wolfgang Huber, Moritz Gerstung, Josh Moore, Fabian Joachim Theis, Oliver Stegle
SpatialData: an open and universal data framework for spatial omics. Nature methods (2024)
Tobias Roider, Marc-Andrea Baertsch, Donnacha Fitzgerald, Harald Vöhringer, Berit J Brinkmann, Felix Czernilofsky, Mareike Knoll, Laura Llaó-Cid, Anna Mathioudaki, Bianca Faßbender, Maxime Herbon, Tobias Lautwein, Peter-Martin Bruch, Nora Liebers, Christian M Schürch, Verena Passerini, Marc Seifert, Alexander Brobeil, Gunhild Mechtersheimer, Carsten Muller-Tidow, Oliver Weigert, Martina Seiffert, Garry P Nolan, Wolfgang Huber, Sascha Dietrich
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities. Nature cell biology 26 (3) (2024)
Monika Pepelnjak, Britta Velten, Nicolas Näpflin, Tatjana von Rosen, Umberto Capasso Palmiero, Jeong Hoon Ko, Heather D Maynard, Paolo Arosio, Eilika Weber-Ban, Natalie de Souza, Wolfgang Huber, Paola Picotti
In situ analysis of osmolyte mechanisms of proteome thermal stabilization. Nature chemical biology (2024)
JunYan Lu, Britta Velten, Bernd Klaus, Mauricio Ramm, Wolfgang Huber, Rachel Coulthard-Graf
The changing career paths of PhDs and postdocs trained at EMBL. eLife 12 (2023)
Nora Liebers, Peter-Martin Bruch, Tobias Terzer, Miguel Hernandez-Hernandez, Nagarajan Paramasivam, Donnacha Fitzgerald, Heidi Altmann, Tobias Roider, Carolin Kolb, Mareike Knoll, Angela Lenze, Uwe Platzbecker, Christoph Röllig, Claudia Dorothea Baldus, Hubert Serve, Martin Bornhäuser, Daniel Hübschmann, Carsten Muller-Tidow, Friedrich Stölzel, Wolfgang Huber, Axel Benner, Thorsten Zenz, Junyan Lu, Sascha Dietrich
Ex vivo drug response profiling for response and outcome prediction in hematologic malignancies: the prospective non-interventional SMARTrial. Nature cancer (2023)
Constantin Ahlmann-Eltze, Wolfgang Huber
Comparison of transformations for single-cell RNA-seq data. Nature methods (2023)
Thomas Schwarzl, Sudeep Sahadevan, Benjamin Lang, Milad Miladi, Rolf Backofen, Wolfgang Huber, Matthias W Hentze, Gian Gaetano Tartaglia
Improved discovery of RNA-binding protein binding sites in eCLIP data using DEWSeq. Nucleic acids research (2023)
Nils Kurzawa, Isabelle Rose Leo, Matthias Stahl, Elena Kunold, Isabelle Becher, Anastasia Audrey, Georgios Mermelekas, Wolfgang Huber, André Mateus, Mikhail M Savitski, Rozbeh Jafari
Deep thermal profiling for detection of functional proteoform groups. Nature chemical biology (2023)
Katharina Imkeller, Giulia Ambrosi, Nancy Klemm, Ainara Claveras Cabezudo, Luisa Henkel, Wolfgang Huber, Michael Boutros
Metabolic balance in colorectal cancer is maintained by optimal Wnt signaling levels. Molecular systems biology 18 (8) (2022)
Peter-Martin Bruch, Holly Ar Giles, Carolin Kolb, Sophie A Herbst, Tina Becirovic, Tobias Roider, Junyan Lu, Sebastian Scheinost, Lena Wagner, Jennifer Huellein, Ivan Berest, Mark Kriegsmann, Katharina Kriegsmann, Christiane Zgorzelski, Peter Dreger, Judith Barbara Zaugg, Carsten Müller-Tidow, Thorsten Zenz, Wolfgang Huber, Sascha Dietrich
Drug-microenvironment perturbations reveal resistance mechanisms and prognostic subgroups in CLL. Molecular systems biology 18 (8) (2022)
Alina Batzilla, JunYan Lu, Jarno Kivioja, Kerstin Putzker, Joe Lewis, Thorsten Zenz, Wolfgang Huber
Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling. PLoS computational biology 18 (8) (2022)
Tobias Roider, Berit J Brinkmann, Vladislav Kim, Mareike Knoll, Carolin Kolb, Philipp M Roessner, Marie Bordas, Peter Dreger, Carsten Muller-Tidow, Wolfgang Huber, Martina Seiffert, Sascha Dietrich
An autologous culture model of nodal B-cell lymphoma identifies ex vivo determinants of response to bispecific antibodies. Blood advances 5 (23) (2022)
Sophie A Herbst, Mattias Vesterlund, Alexander J Helmboldt, Rozbeh Jafari, Ioannis Siavelis, Matthias Stahl, Eva C Schitter, Nora Liebers, Berit J Brinkmann, Felix Czernilofsky, Tobias Roider, Peter-Martin Bruch, Murat Iskar, Adam Kittai, Ying Huang, JunYan Lu, Sarah Richter, Georgios Mermelekas, Husen Muhammad Umer, Mareike Knoll, Carolin Kolb, Angela Lenze, Xiaofang Cao, Cecilia Österholm, Linus Wahnschaffe, Carmen Herling, Sebastian Scheinost, Matthias Ganzinger, Larry Mansouri, Katharina Kriegsmann, Mark Kriegsmann, Simon Anders, Marc Zapatka, Giovanni Del Poeta, Antonella Zucchetto, Riccardo Bomben, Valter Gattei, Peter Dreger, Jennifer A Woyach, Marco Herling, Carsten Muller-Tidow, Richard Rosenquist, Stephan Stilgenbauer, Thorsten Zenz, Wolfgang Huber, Eugen Tausch, Janne Lehtiö, Sascha Dietrich
Proteogenomics refines the molecular classification of chronic lymphocytic leukemia. Nature communications 13 (1) (2022)
Nils Kurzawa, Isabelle Becher, Sindhuja Sridharan, Holger Franken, André Mateus, Simon Anders, Marcus Bantscheff, Wolfgang Huber, Mikhail M Savitski
Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles. Nature communications 12 (1) (2021)
Fabienne Meier-Abt, JunYan Lu, Ester Cannizzaro, Marcel F Pohly, Sandra Kummer, Sibylle Pfammatter, Laura Kunz, Ben C Collins, Ferran Nadeu, Kwang-Seok Lee, Peng Xue, Myriam Gwerder, Michael Roiss, Jennifer Hüllein, Sebastian Scheinost, Sascha Dietrich, Elias Campo, Wolfgang Huber, Ruedi Aebersold, Thorsten Zenz
The Protein Landscape of Chronic Lymphocytic Leukemia (CLL). Blood (2021)
Magdalena Zimoń, Yunfeng Huang, Anthi Trasta, Aliaksandr Halavatyi, Jimmy Z Liu, Chia-Yen Chen, Peter Blattmann, Bernd Klaus, Christopher D Whelan, David Sexton, Sally John, Wolfgang Huber, Ellen A Tsai, Rainer Pepperkok, Heiko Runz
Pairwise effects between lipid GWAS genes modulate lipid plasma levels and cellular uptake. Nature communications 12 (1) (2021)
Nils Kurzawa, Isabelle Becher, Sindhuja Sridharan, Holger Franken, André Mateus, Simon Anders, Marcus Bantscheff, Wolfgang Huber, Mikhail M Savitski
A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles. Nature communications 11 (1) (2020)
Katharina Imkeller, Giulia Ambrosi, Michael Boutros, Wolfgang Huber
gscreend: modelling asymmetric count ratios in CRISPR screens to decrease experiment size and improve phenotype detection. Genome biology 21 (1) (2020)
Tobias Roider, Julian Seufert, Alexey Uvarovskii, Felix Frauhammer, Marie Bordas, Nima Abedpour, Marta Stolarczyk, Jan Philipp Mallm, Sophie A Herbst, Peter-Martin Bruch, Hyatt Balke-Want, Michael Hundemer, Karsten Rippe, Benjamin Goeppert, Martina Seiffert, Benedikt Brors, Gunhild Mechtersheimer, Thorsten Zenz, Martin Peifer, Björn Chapuy, Matthias Schlesner, Carsten Muller-Tidow, Stefan Fröhling, Wolfgang Huber, Simon Anders, Sascha Dietrich
Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels. Nature cell biology 22 (7) (2020)
Benjamin Haibe-Kains, George Alexandru Adam, Ahmed Hosny, Farnoosh Khodakarami, null null, Levi Waldron, Bo Wang, Chris McIntosh, Anna Goldenberg, Anshul Kundaje, Casey S Greene, Tamara Broderick, Michael M Hoffman, Jeffrey T Leek, Keegan Korthauer, Wolfgang Huber, Alvis Brazma, Joelle Pineau, Robert Tibshirani, Trevor Hastie, John P A Ioannidis, John Quackenbush, Hugo J W L Aerts
Transparency and reproducibility in artificial intelligence. Nature 586 (7829) (2020)
Mary J Goldman, Junjun Zhang, Nuno A Fonseca, Isidro Cortes-Ciriano, Linda Xiang, Brian Craft, Elena Piñeiro-Yañez, Brian D O'Connor, Wojciech Bazant, Elisabet Barrera, Alfonso Muñoz-Pomer, Robert Petryszak, Anja Füllgrabe, Fátima Al-Shahrour, Maria Keays, David Haussler, John N Weinstein, Wolfgang Huber, Alfonso Valencia, Peter J Park, Irene Papatheodorou, Jingchun Zhu, Vincent Ferretti, Miguel Vazquez
A user guide for the online exploration and visualization of PCAWG data. Nature communications 11 (1) (2020)
Arne H Smits, Frederik Ziebell, Gerard Joberty, Nico Zinn, William F Mueller, Sandra Clauder-Münster, Dirk Eberhard, Maria Fälth Savitski, Paola Grandi, Petra Jakob, Anne-Marie Michon, Hanice Sun, Karen Tessmer, Tilmann Bürckstümmer, Marcus Bantscheff, Lars M Steinmetz, Gerard Drewes, Wolfgang Huber
Biological plasticity rescues target activity in CRISPR knock outs. Nature methods 16 (11) (2019)
Alexander Jethwa, Mikołaj Słabicki, Jennifer Hüllein, Marius Jentzsch, Vineet Dalal, Sophie Rabe, Lena Wagner, Tatjana Walther, Wolfram Klapper, null null, Hanibal Bohnenberger, Mandy Rettel, JunYan Lu, Arne H Smits, Frank Stein, Mikhail M Savitski, Wolfgang Huber, Yael Aylon, Moshe Oren, Thorsten Zenz
TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma. Blood 131 (25) (2018)
Xiaofei Zhang, Arne H Smits, Gabrielle Ba van Tilburg, Huib Ovaa, Wolfgang Huber, Michiel Vermeulen
Proteome-wide identification of ubiquitin interactions using UbIA-MS. Nature protocols 13 (3) (2018)
Ricard Argelaguet, Britta Velten, Damien Arnol, Sascha Dietrich, Thorsten Zenz, John C Marioni, Florian Buettner, Wolfgang Huber, Oliver Stegle
Multi-Omics Factor Analysis-a framework for unsupervised integration of multi-omics data sets. Molecular systems biology 14 (6) (2018)
Wolfgang Huber
A clash of cultures in discussions of the P value. Nature methods 13 (8) (2018)
Lars Velten, Simon F Haas, Simon Raffel, Sandra Blaszkiewicz, Saiful Islam, Bianca P Hennig, Christoph Hirche, Christoph Lutz, Eike C Buss, Daniel Nowak, Tobias Boch, Wolf-Karsten Hofmann, Anthony D Ho, Wolfgang Huber, Andreas Trumpp, Marieke A G Essers, Lars M Steinmetz
Human haematopoietic stem cell lineage commitment is a continuous process. Nature cell biology 19 (4) (2017)
E I Andersson, S Pützer, B Yadav, O Dufva, S Khan, L He, Leopold Sellner, A Schrader, G Crispatzu, M Oleś, H Zhang, S Adnan-Awad, S Lagström, D Bellanger, J P Mpindi, Samuli Eldfors, T Pemovska, P Pietarinen, A Lauhio, K Tomska, C Cuesta-Mateos, E Faber, S Koschmieder, T H Brümmendorf, S Kytölä, E-R Savolainen, T Siitonen, P Ellonen, Olli Kallioniemi, K Wennerberg, W Ding, M-H Stern, Wolfgang Huber, Emma I Andersson, J Tang, T Aittokallio, T Zenz, M Herling, S Mustjoki
Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling. Leukemia 32 (3) (2017)
M Słabicki, K S Lee, A Jethwa, Leopold Sellner, Francesca Sacco, T Walther, J Hüllein, S Dietrich, B Wu, D B Lipka, C C Oakes, S Mamidi, B Pyrzyńska, M Winiarska, M Oleś, M Seifert, C Plass, M Kirschfink, M Boettcher, J Gołąb, Wolfgang Huber, S Fröhling, T Zenz
Dissection of CD20 regulation in lymphoma using RNAi. Leukemia 30 (12) (2016)
Nikolaos Ignatiadis, Bernd Klaus, Judith B Zaugg, Wolfgang Huber
Data-driven hypothesis weighting increases detection power in genome-scale multiple testing. Nature methods 13 (7) (2016)
Benedikt M Beckmann, Rastislav Horos, Bernd Fischer, Alfredo Castello, Katrin Eichelbaum, Anne-Marie Alleaume, Thomas Schwarzl, Tomaž Curk, Sophia Foehr, Wolfgang Huber, Jeroen Krijgsveld, Matthias W Hentze
The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs. Nature communications 6 (2015)
Holger Franken, Toby Mathieson, Dorothee Childs, Gavain M A Sweetman, Thilo Werner, Ina Tögel, Carola Doce, Stephan Gade, Marcus Bantscheff, Gerard Drewes, Friedrich B M Reinhard, Wolfgang Huber, Mikhail M Savitski
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry. Nature protocols 10 (10) (2015)
Friedrich B M Reinhard, Dirk Eberhard, Thilo Werner, Holger Franken, Dorothee Childs, Carola Doce, Maria Fälth Savitski, Wolfgang Huber, Marcus Bantscheff, Mikhail M Savitski, Gerard Drewes
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins. Nature methods 12 (12) (2015)
Wolfgang Huber, Vincent J Carey, Robert Gentleman, Simon Anders, Marc Carlson, Benilton S Carvalho, Hector Corrada Bravo, Sean Davis, Laurent Gatto, Thomas Girke, Raphael Gottardo, Florian Hahne, Kasper D Hansen, Rafael A Irizarry, Michael Lawrence, Michael I Love, James MacDonald, Valerie Obenchain, Andrzej K Oleś, Hervé Pagès, Alejandro Reyes, Paul Shannon, Gordon K Smyth, Dan Tenenbaum, Levi Waldron, Martin Morgan
Orchestrating high-throughput genomic analysis with Bioconductor. Nature methods 12 (2) (2015)
Philip Brennecke, Alejandro Reyes, Sheena Pinto, Kristin Rattay, Michelle Nguyen, Rita Küchler, Wolfgang Huber, Bruno Kyewski, Lars M Steinmetz
Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells. Nature immunology 16 (9) (2015)
Christina Laufer, Bernd Fischer, Wolfgang Huber, Michael Boutros
Measuring genetic interactions in human cells by RNAi and imaging. Nature protocols 9 (10) (2014)
Yusuke Ohnishi, Wolfgang Huber, Akiko Tsumura, Minjung Kang, Panagiotis Xenopoulos, Kazuki Kurimoto, Andrzej K Oleś, Marcos J Araúzo-Bravo, Mitinori Saitou, Anna-Katerina Hadjantonakis, Takashi Hiiragi
Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages. Nature cell biology 16 (1) (2013)